Generic Name Classification Dose/ Route/ Modes of Action Indication Adverse Nursing

(Brand Name) Frequency/ Reaction Consideration

Stock Dose
Hyoscine-n- PC: IV: HBB > To relieve pain CNS: dizziness, >Be alert for
Butylbromide ↓ during labor and headache, adverse
Anticholinergic 1 mg/ml
(Buscopan) Inhibits promotes restlessness, reactions and
muscarinic contraction that disorientation, drug
TC: aids in the
actions of irritability, fever interactions.
antimuscarinic, effacement of
acetylcholine in >Encourage pt.
antiemetic, the cervix.
the GI: constipation, to void
antivertigo drug,
ANS dry mouth,
antiparkinsonism >Monitor BP for
↓ nausea,
Affecting neural vomiting possible
pathway hypotension.
↓ CV: palpitations, >Monitor
Relieves tachycardia, cervical
spasticity, flushing effacement and
nausea and dilatation.
vomiting; EENT: dilated
reduces pupils, blurred
secretions; and vision,
blocks cardiac photophobia,
vagal reflexes. dysphagia
↓ GU: urinary
Promotes hesitancy,
cervical urinary
effacement retention
Skin: rash,
dryness
 Generic Name Classification Dose/ Route/ Modes of Action Indication Adverse Nursing
(Brand Name) Frequency/ Reaction Consideration
Stock Dose
Oxytocin PC: Exogenous I.V.: 10-40 units Oxytocin Indication: CV: > Monitor and
(Pitocin) by I.V. infusion ↓ Induction of hypertension; record
Agent
in 1000 mL of Causes potent labor increased heart uterine
TC: oxytocic,
intravenous fluid and at term; control rate, contractions,
lactation
at a rate selective of systemic venous heart rate, BP,
stimulant
sufficient to stimulation of postpartum return, and intrauterine
control uterine uterine and bleeding; cardiac pressure,
atony. mammary gland adjunctive output, and fetal heart rate,
smooth muscles therapy in arrhythmias and
↓ management of blood loss q15.
producing abortion CNS: seizures,
sustained coma from >Be alert for
contractions water
↓ adverse
intoxication
Induces labor Reaction
and GI:
milk ejection Nausea, >Monitor I/O.
and vomiting, Antidiuretic
reduces post effect may
partum GU: titanic lead to fluid
bleeding uterine overload,
contractions, seizures, and
abruption coma
placentae,
impaired >never give
uterine blood oxytocin
flow, simultaneously
pelvic by more
hematoma than one route.

Hematologic: >have 20%

Afibrinogenemia solution
magnesium
sulfate
Respi: available for
anoxia, asphyxia relaxation
of the
myometrium.

>If contractions
are less
than 2 minutes
apart, if
they’re above
50mm Hg
,or if they last
90seconds
or longer, stop
infusion,
and turn patient
on her
side, and notify
prescriber
 Generic Name Classification Dose/ Route/ Modes of Indication Adverse Nursing
(Brand Name) Frequency/ Action Reaction Consideration
Stock Dose
Promethazine Chemical: I.V./ I.M.: Promethazine > Preoperative,   CNS: >Monitor BP,
HCl Phenothiazine HCl postoperative, pulse
25 – 50 mg, neuroleptic
(Phenergan) derivative ↓ or obstetric and respirator
single dose Blocks receptor sedation. malignant y rate
Therapeutic: sites within the syndrome, frequently.
Sedative- CNS confusion,
Hypnotic, ↓ >Assess level
disorientation,
Antihistamine, Directly reducing of sedation
stimuli to the sedation, after admin-
Antiemetic.
brain dizziness, istration
↓ extrapyramidal
Sedation >Assess
reaction, fatigue,
patient for
insomnia, nausea and
nervousness; vomiting
before and
EENT: blurred after admin-
istration.
vision, diplopia,
tinnitus; >Administer
each 25mg
CV: bradycardia, slowly over at
least 1 hr.
hypertension,
hypotension, >Do not give
tachycardia; rectal supp or
tabs to
children
GI: constipation,
younger than
drug-induced
2 years old
hepatitis, dry
because of
mouth; risk of
fetal respirato
Derm: rydepressions
photosensitivity,
>Give IM
rashes; injections
deep into
Hemat: blood muscle
dyscrasias
>Do not
administer
SQ, tissue
necrosis may
occur

>Arteriospas
ms and
gangrene of
artery may
occur when
administered
intra-
arterially.

>Reduce
dosage of
barbiturates
given
concurrently
within
promethazine
by least half.
 Generic Name Classification Dose/ Route/ Modes of Action Indication Adverse Nursing
(Brand Name) Frequency/ Reaction Consideration
Stock Dose
Butorphanol Chemical: I.V.: Butorphanol >To manage CNS: >Use cautiously
Tartrate Opioid 0.5-2mg q3/ Tartrate pain. Anxiety, in patients with
(Stadol) PRN ↓ Confusion, depression ,
Therapeutic: Binds with >As adjunct to Difficulty suicidal
Anestehsia specific CNS provide speaking, tendency,
adjunct, Narcotic Receptors anesthesia euphoria history of
analgesic ↓ floating feeling, hepatic or renal
Alters headache. dysfunction.
perception and
emotional CV: >Butorphanol
response to pain Chest Pain, can increase
hypotension, cardiac
palpitations, workload. Use it
tachycardia, cautiously in
vasodilation patients with
M.I., Vnetricular
EENT: dysfunction or
Blurred vision, coronary
dry mouth, ear insufficiency.
pain, epistaxis
>Be aware that
GI: the drug has the
Anorexia, high potential
constipation, for abuse.
epigastric pain
>Frequently
RESP: monitor Blood
Apnea, pressure.
bronchitis,
cough, dyspnea, >Asses
shallow respiratory
breathing status closely
because drug
SKIN: causes
Clammy skin, respiratory
pruritus depression.
 Generic Name Classification Dose/ Route/ Modes of Action Indication Adverse Nursing
(Brand Name) Frequency/ Reaction Consideration
Stock Dose
Vitamin K Fat soluble 0.5-1mg within 1 The mechanism >To prevent CV: >Be aware that
(Phytonadione) vitamins, hour after birth. of action of hemorrhagic Cardiac Arrest some Vitamin K
(Aquamephyton) Antifibrinolytic vitamin K is disease in Respi: solutions have
agents discussed in neonates. benzyl alcohol.
Respiratory
terms of a new Don’t adminster
carbanion model Arrest
these solutions
that mimics the to neonates or
proton Others: immature
abstraction from infants because
Anaphylaxis,
the gamma of high risk of
position of Shock
fatal toxic
protein-bound syndrome,
glutamate. This which may
is the essential
include CNS,
step leading to
respiratory,
carboxylation
circulatory and
and activation of
renal
the blood-
impairment and
clotting proteins.
metabolic
The model
comprises an acidosis.
oxygenation that
is coupled to >Be aware that
carbon-carbon Vitamin K is light
bond formation, sensitive.
as is the
oxygenation of
vitamin K
hydroquinone to
vitamin K oxide.
The model
hypothesis is
also supported
by the
mechanism of
inhibition of the
carboxylase by
HCN, which acts
as an acid-base
inhibitor rather
than a metal-
complexing
inhibitor. The
new model
postulates a
dioxetane
intermediate
that explains the
presence of a
second atom of
18O (from 18O2)
incorporated
into vitamin K
oxide in the
course of the
enzymatic
carboxylation.
Finally, the
chemistry
developed here
has been used to
define the active
site of vitamin K
hydroquinone as
the carbon-
carbon bond
adjacent to the
methyl group