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DEFINING EVIDENCE, IMPLEMENTATION, being learned and technology offers momentum.

ANDTRANSLATIONAL SCIENCES Struggling with what it takes to apply evidence


in ways that promo lasting, safe, cost-
EBP adds action to the use effective, and high quality care is gradually
of evidence. leading to measurable outcome improvements.
EBP provides processes for TOOLS USED FOR SUPPORTING TRANSLATION
using evidence to generate OF DATA TO INFORMATION TO KNOWLEDGE
knowledge. It is a widely TO WISDOM
used term that is easier to
define than to Nursing is an information-based discipline (Graves&
operationalize. Corcoran, 1989). Nursing informatics unites nursing
sScience, computer science, and information science
in ways that transform what this means.
The evolution of nursing as an information-based
EBP is a "problem solving approach to clinical decision- discipline changes how data, information, and
making that involves the Conscientious use of the best knowledge are managed in nursing practice (Staggers
available evidence (including a systematic search for & Thompson, 2002)
and critical appraisal of the most relevant evidence) to
answer a clinical question with one's own clinical What is learned through research, evaluation, quality
expertise along with patient values and preferences to improvenmenty and safety activities contributes to
improve outcomes for individuals, groups, communities wisdom.
and systems" (2011).
Once wisdom achieved, feedback contributes to
- Melnyk & Fineout-Overholt ongoing improve and to generate new hypotheses

Implementation science- is the study of methods to


promote the integration of research findings and .EVOLUTION OF EVIDENCE
evidence into healthcare policy and practice (National How Evidence ls Generated
Institutes of Health Fogarty International Center,
2013). Research results can be used to address important
clinical questions after being accepted as part of the
evidence base for a clinical question.
Implementation science is relevant to nurses and
others who work directly with patients because it
Research results become part of the evidence base for
focuses on what is needed to improve outcomes.
a disease or condition only after going through rigorous
and explicit processes designed to find, Compare, and
EBP is also central to what Titler and Everett (2001)
combine data. Reviews of research findings involve
define as "translational research” which tests the
critical appraisal using explicit and objective inclusion
effect of interventions to facilitate the rate and extent
and exclusion criteria.
to which evidence-based practices are adopted (2001).
 Such criteria identifies studies to be considered
Although defined in different ways, Ttranslation
when trying to answer a clinical question, such
emphasizes processes such as dissemination and
as which nursing interventions for reducing
implementation of empirical, patient-centered findings
pain are the most effective and scientifically
that have been rigorously tested in broad populations
grounded. An organized approach is used to
and sub-groups before deemed ready for
identify valid and reliable peer reviewed
implementation in clinical practice. Feedback and
publications to be considered further.
evaluation often follow implementation.
 Rigorous methods determine the efficacy of
specific interventions and their effectiveness
As evidence moves through dissemination,
when used with real patients outside of tightly
implementation, evaluation, and other stages,
controlled conditions.
evidence-driven care is fostered through
 Advanced statistical analysis, using Bayesian or
iterative and interactive processes (Harrison &
other methods, helps understand how best to
Graham, 2012). Although there is growing
combine findings.
awareness of the importance of evidence
uptake, we are in the early stages of knowing
how to systematically operationalize translation Through these techniques, systematic reviews pull
and sustain improvements after satety and together what is known about the benefits and harms
quality related interventions end. But much is of the interventions surrounding a clinical question.
It also helps reveal the trade-offs associated with key manage healthy choices and gain online support.
treatment, diagnostic, or prevention interventions.
 E-mail, evidence, and twitter alert systems
The Origins of Evidence-Based Practice - involve voluntary registration based on clinical
interest in order to receive alerts or updates related
The term EBP became popular after 1992 when first to interventions.
used by Gordon Guyatt and a group he led at
McMaster University (Guyatt,2002). - Ideal for receiving information about new
evidence or to send alerts about a safety concern,
David L. Sackett described EBP as the best use of such as spreading information that a medication
current best evidence in making decision about the care has been found dangerous.
of individual patients.
Alerts - are often linked to resources that allow access
EBP came to describe a systematic approach to to the scientific literature matched to a specific clinical
organizing, collecting and using research findings in interest.
ways that contribute to the best possible outcomes. - Alerts also deliver information that has
already been rated.
INFORMATICS TOOLS THAT PROMOTE AND
FACILITATE KNOWLEDGE GENERATION OF Technology platform
EVIDENCE - Provide assessments and interventions.
- Allow for tracking and feedback about the
Nurses help themselves, their students, patients, patient's use of the tool to a nurse or other
professional nursing groups, and their clinical team clinician.
understand whether the information commonly - Some of these tools are interactive and Web-
downloaded about a specific condition or disease is based or may be
accurate (valid and reliable) while pointing out potential run from a DVD,
benefits and harms. local computer, or
Caution may be needed if information is being used flash-drive.
without critical review.
Mobile tools - such as
A nurse can generate (and regularly update) lists of phones and tablets, are
credible online evidence-based resources to suggest to also used.
patients, families, and other providers.
Nurses help by addressing
Because evidence becomes outdated, nurses can what is lost (in terms of non-verbal interactions, cues,
monitor to be sure that their teams and patients have and physical assistance) versus what is gained (through
current information, including understanding any legal access and convenience) when a technology-based
and ethical concerns or privacy issues. intervention works with other non-nursing clinicians.
Nurses can then tailor these tools to the needs of
Criteria to evaluate health-related information found specific patients.
online has been developed and disseminated by several
organizations including HON Code, American Medical MODELS AND THEORETICAL FRAMEWORKS
Association, Internet Health Care Coalition, Hi-Ethics, CONNECTING CRITICAL THINKING TO PROCESS
and Med Certain (Berland, Elliott, & Morales, 2001). THAT SUPPORT THE USE OF EVIDENCE IN
NURSING PRACTICE
Criterias designed for evaluating health and medical
information, and increasingly the rest of us are using Models and frameworks help link critical thinking step-
mobile and portable devices, including tablets, portable wise processes that promote the use of evidence
computers, and smart phones to seek the evidence and ,including accounting for factors that lead to safe and
engage with actual automated interventions (such as lasting outcome and organizational improvements.
online counselling).
Theories help nurses critically examine the contextual
 Web-based screening, prevention, outreach, and factors, assumptions, and influences surrounding
intervention tools implementation.
- help patients access valid and reliable
evidence about fundamental public health issues, such Using models and frameworks helps nurses prepare a
as obesity, stress management, and tobacco cessation, cogent plan for translation within complicated
while also helping patients track, reinforce, and situations, such as the implementation of an EBP when
change and disruption are anticipated.
Namusoko, Waiswa, and Wallinn (2012) who used
Contributed to theories : PARIHS as a framework for knowledge translation in
Ugenda
Donabedian's (1980) structure, process, and
outcomes framework, which focus on problem Rycroft-Malone et al. (2012) and McCormack
solving. et al. (2013)
Realist review and synthesis -focuses on
Rogers Diffusion of Innovations model, the Funk Model, understanding the mechanisms by which an
the PRECEDE Model, the Chronic Care Model, the intervention works or does not work.
PARiHS Model, the Stetler Model, the lowa Model and
Translation Research Model, Russworm's and Hynes, Whittier, and Owens (2013)
Larrabee's Model, the ARCC Model, Kitson's Framework, QUERI model - demonstrate how HIT
Melnyk and Fineout-Overholt's Model of EBP, the Lean approaches could be characterized as facilitators or
Framework, the PICOT Model, the QUERI model, barriers to implementation. Two pathways were found
Rossworm and Larrabee's Model, and the Institute for to contribute to translation:
Healthcare Improvement's breakthrough model.
(1) compliance and collaboration with information
Specific contributions: technology policies and procedures;
(2) operating within organizational policies and building
Roger's understanding of "attributes" (including collaborations with end users, clinicians, and
complexity) and Alison Kitson's emphasis on administrators; and obtaining and maintaining research
understanding the environment, including the resources and ovals.
importance of a clearly articulated collaborative
Knowledge Translation (KT approach that can be Harrison. Graham, van den Hoek, Dogherty,Carley, and
embedded into the research design (Kitson, Powell, Angus (2013)
Hoon, Newbury, Wilson, & Beilby, 2013). CAN-IMPLEMENT- refer to the importance of
CAN planning support in development of a framework

The Promoting Action on Research INFORMATICS TOOLS THAT PROMOTE THE USE
Implementation Health Services (PARIHS) OF EVIDENCE AND APPLY KNOWLEDGE TO
framework helps define and measure key factors PRACTICE
leading to successful implementation and has been
widely used, including by Squires et al (2012) who  Adoption of evidence is now providing access
designed strategies to implement resear based policies to a single clinical practice guideline or
and procedures. Webinar.
 Shifted to understanding the conditions that
Dr. Marita Titler foster ongoing and lasting change once the
Leadership for AHRQ's TRIP initiatives and evidence is found and introduced, often using
has also studied the context in which EBPs are multiple implementation strategies.
translated. Important influences found include:  Implementation strategies being used to apply
the evidence are also grounded in science.
(1) tne nature of the innovation strength of evidence)
and What will facilitate implementation and what will be the
(2) the manner it is communicated to nurses and barriers? Under what conditions is successful
physician (Herr et al 2012; Titler 2010; Titler 2011). implementation anticipated?

Dr. Carole Estabrooks describe the importance of  Collecting data was challenging during this
considering the significant needs found in complex care study because the patients did not want to be
environments, such as nursing homes (Estabrooks com critical. But sustained improvement depended
et al., 2013). upon understanding patient perspectives about
the benefits and challenges of care
Dr. Cheryl Stetler coordination and home telehealth.
Stetler Model of Evidence-Based
shaped the evolution of EBP and also synthesized Understanding the influence of patient perceptions
literature on use PARIHS framework, including assured that expectations could be met. This facilitated
development of a companion guide to assist translation.
researchers using PARIHS
The PARIHS framework is widely used
internationally, including Bergström, Peterson,
The information explosion presents challenges to  HIT supports EBP by making it easier to access
healthcare providers who seek new evidence on an and use evidence and evidence-based tools,
ongoing basis. such as automated reminders.

 Evidence-based clinical or point-of-care "Meaningful use” Affordable Care Act (ACA)


resources, especially literature reviews, make it promote the use of evidence to
easier to access information. drive improved outcomes, quality,
 Easy access helps nurses avoid making and safety.
decisions based on experience alone or on the
advice of a colleague or teacher.  Carefully planned use of HIT
 Evidence-based tools help by organizing contributes to new and
evidence and aiding cognition in evidence restructured systems that
selection, interpretation, implementation, and address the over-use,
evaluation. When coupled with technology, underuse, and misuse of
evidence-based tools become central to healthcare (Doebbling and
practice. Flanagan, 2011).
 Nurses are challenged to create, find, test,  Understanding the context in which HIT and
implement, and evaluate the right evidence- EBP merge means studying what works and
based tools. Such tools include complex does not work during translation.
tecnnology new to some nurses, including
innovate support using mobile health-based. The Use of Electronic Health Records (EHRs).
Decision support includes integrating
experience with the evidence. Automated tools are often linked to computerized
health records, such as:
 Evidence-based tools are not "cookbooks"
when implementing a clinical intervention using Electronic Health Record (EHR)
an automated evidence-based tool, clinical - refers to
judgment is needed because translation and patient records collected
decision support overlap, each is inherently across settings, ideally
multi-disciplinary. to support care along
the continuum of an
 Nursing joins public health medicine, and other individual's lifespan.
health disciplines in seeking better
understanding of the conditions needed to - provides a
successfully apply evidence to decisions vehicle to transmit
support in real situation, then measure the evidence by embedding
impact and feed data back after evaluation. evidence-based tools
 Computer-literate nurses brings to their teams into routine nursing
knowledge of how to identify and then critically functions.
appraise the best available evidence or use the - Can be especially powerful if the data are
evidence-based tool(s) to support decisions. standardized and copied into data warehouses or
datamarts where data can be easily exchanged for
 Explaining evidence includes understanding the follow-up purposes.
unintended consequences that accompany
translation and dealing with uncertainty when Because EHR promotes meaningful use of technology
evidence is incomplete, misleading, or and enhances information exchange, it plays a growing
contradictory role in the translation of evidence into practice.

For some patients or sub-groups, multiple evidence-  Later, these data may become part of the body
based tools may need to be translated at the same time of evidence used to update the next version of
or specific interventions from different evidence-based a clinical practice guideline.
tools tried together.
 Poe, Abbott, and Pronovost (2011) used peer
 Models help nurses create a cogent plan that coaches to build and sustain competencies
pulls these interventions together. needed by nurses using EHR in clinical settings.
 Decision support now occurs within the context
of change.
 Both satisfaction and confidence increased It includes automated templates for orders and
through the use of an evidence-based coach referral that link to reminders or other forms evidence.
intervention.
Computerized pathways, flow charts, algortihms, and
 Ongoing diligence is needed to assure the critical paths are CDS tools that facilitate
timeliness of updates, the accuracy of input as implementation in ways that reduce errors and
well as the usefulness and safety of output promoter compliance.

Automated reminders are a form of decision support


Applying Evidence in Informatics to Improve used in “real time” or at the point of patient contact.
Safety and Quality of Care
Clinical practice guidelines (CPGs)
Nurses seeking to improve the safety and quality of
care can often find literature review, systematic "systematically developed statements to assist
reviews, meta-analyses, or evidence based tools that practitioners and patient decisions about appropriate
address their specific goals or are relevant to their health care for specific circumstances".
areas of practice.
Guidelines are designed to support the decision-making
Technology-based tools - used within an organization in processes in patient care.
ways that makes it easier and faster to implement
evidence-based tools while also making it harder to The content of a guideline is based on a systematic
harm a patient. review of clinical evidence - the main source for
evidence-based care.
Electronic tools – used to promote quality and safety
offer a promising approach. The impacts should need
Purposes of guidelines
to be evaluated prior to, during, and after
implementation.
 To describe appropriate care based on the best
A dynamic high functioning quality and safety culture available scientific evidence and broad
required nurses continually examine the conditions consensus;
needed to foster ongoing learning.  To reduce inappropriate variation in practice;
 To provide a more rational basis for referral;
Performance, quality, and safety do not come through  To provide a focus for continuing education;
the technology alone but are influenced by those who  To promote efficient use of resources;
implement, monitor, and use the technology.  To Act as focus for quality control, including
audit;
Innovation and progress are impeded by fear.  To highlight shortcomings of existing literature
and suggest appropriate future research.
The tools associated with implementing bar-coded
patient wrist bracelets that match automated records to Clinical protocols can be seen as more specific than
prevent patients from receiving wrong medication or guidelines, defined in greater detail.
surveillance systems designed to detect healthcare-
acquaired infections are only useful when safely Protocols provide "a comprehensive set of rigid criteria
implemented and maintained. outlining the management steps for a single clinical
condition or aspects of organization"
EVIDENCE EMBEDDED INTO CLINICAL
DECISION SUPPORT Computerized guidelines
TOOLS (CDS)
Computerized guidelines encode evidence-based
Evidence is often recommendations for and can automatically generate
embedded in Clinical recommendations about what medical procedures to
Decision Support (CDS) perform tailored for an individual patient.
tools. Computerized guidelines offer benefits over and
above those offered by paper-based guidelines:
CDS – captures the
processes used to enhance  They offer a readily accessible reference,
health-related decision and actions with pertinent, providing selective access to guideline
organized clinical knowledge and patient information, to knowledge.
improve health and healthcare delivery.
 They help reveal errors in the content of a results. Variables that affect the adoption of guidelines
guideline; include qualities of the guidelines, characteristics of the
 They help improve the clarity of a guideline, health care professional, characteristics of the practice
e.g. in decision criteria and clinical setting, incentives, regulation and patient factors. The
recommendations; interventions were shown to be weak (didactic,
 They help offer better descriptions of patient traditional continuing medical education and mailings),
states; moderately effective (audit and feedback, especially
 They can automatically propose timely, patient- concurrent, targeted to specific providers and delivered
specific decision support and reminders. by peers or opinion leaders) and relatively strong
(reminder systems, academic detailing and multiple
Guideline Implementation (Translating interventions).
guidelines into practice)
CONCLUSIONS: The evidence shows serious
1. Wollersheim H, Burgers J, Grol R. Clinical guidelines deficiencies in the adoption of CPGs in practice. Future
to improve patient care. Neth J Med. 2005 implementation strategies must overcome this failure
Jun;63(6):188-92. through an understanding of the forces and variables
influencing practice and through the use of methods
that are practice- and community-based rather than
"The aim of clinical guidelines is to improve quality of
didactic "
care by translating new research findings into practice.
There is evidence that the following characteristics
3. Entwistle M and Shiffman RN. Turning Guidelines
contribute to their use: inclusion of specific
into Practice: Making It Happen With Standards.
recommendations, sufficient supporting evidence, a
Health Care and Informatics Review Online
clear structure and an attractive lay out. In the process
[HCRO]. March 2005.
of formulating recommendations, implicit norms of the
target users should be taken into account. Guidelines "Successful delivery of the knowledge incorporated into
should be developed within a structured and guidelines requires a systemic approach which
coordinated program by a credible central organization. integrates knowledge with workflow using existing
To promote their implementation, guidelines could be clinical information systems. Electronic clinical decision
used as a template for local protocols, clinical pathways support (ECDS) systems are the means through which
and interprofessional agreements. " the knowledge embedded in guidelines can be
2. Davis DA, Taylor-Vaisey A. Translating guidelines managed and delivered effectively.
into practice. A systematic review of theoretic
concepts, practical experience and research Barriers to the success of guideline-based ECDS are
evidence in the adoption of clinical practice multiple and include: guideline-related obstacles, both
guidelines. CMAJ. 1997 Aug 15;157(4):408-16. extrinsic to the guideline (organizational and provider
specific obstacles) and intrinsic to the guideline (such
"OBJECTIVE: To recommend effective strategies for as failure to meet adequate standards in guideline
implementing clinical practice guidelines (CPGs). development and format, identification and summary of
evidence, and formulation of recommendations)
DATA SOURCES: The Research and Development electronic decision support issues which include such
Resource Base in Continuing Medical Education, factors as: the extreme complexity of integrated
maintained by the University of Toronto, was searched, decision support systems; poor alignment of the goals
as was MEDLINE from January 1990 to June 1996, of different players; complex technical requirements;
inclusive, with the use of the MeSH heading "practice complex content requirements. Initiatives with the goal
guidelines" and relevant text words. of "improving the guidelines" include the AGREE[ b ]
instrument for guideline quality appraisal, the GuideLine
STUDY SELECTION: Studies of CPG implementation Implementability Appraisal (GLIA) instrument which
strategies and reviews of such studies were selected. predicts barriers to implementation and the COGS
Randomized controlled trials and trials that objectively (Conference on Guideline Standardization) checklist of
measured physicians' performance or health care necessary components of practice guidelines.
outcomes were emphasized.
Numerous projects in "guideline translation" have taken
DATA EXTRACTION: Articles were reviewed to place worldwide, each using different approaches in
determine the effect of various factors on the adoption guideline representation architecture and
of guidelines. implementation. These attempts have advanced the
process of transforming clinical knowledge expressed in
DATA SYNTHESIS: The articles showed that CPG a guideline to a computable format but the absence of
dissemination or implementation processes have mixed commonly agreed standards has created major
difficulties for guideline implementers and decision- PRACTICAL, FIVE-STAGE FRAMEWORK:
support systems designers. Standards are now seen as It includes development of a concrete proposal for
essential to improvements in the process of "guideline change; analysis of the target setting and group to
transformation" for ECDS and underpin a further critical identify obstacles to change; linking interventions to
requirement – the need for ECDS, which has typically needs, facilitators, and obstacles to change;
been viewed as a software application, to be development of an implementation plan; and
considered from a wider systems perspective. ... " monitoring progress with implementation. "
4. Grol R, Grimshaw J. Evidence-based 5. Thomson R, Lavender M, Madhok R. How to ensure
implementation of evidence-based medicine. Jt that guidelines are effective. BMJ. 1995 Jul
Comm J Qual Improv. 1999 Oct;25(10):503-13. 22;311(6999):237-42.

" BACKGROUND: The slow and haphazard process of Summary points: "Guidelines are a way to support
translating research findings into clinical practice effective clinical practice; There is a growing body of
compromises the potential benefits of clinical research. literature on the factors that influence the effectiveness
Most quality improvement (QI) initiatives are based on of guidelines; Reference to these factors will enhance
the beliefs of decision makers rather than on the the likelihood of achieving the objectives of guidelines;
growing theoretical and empirical knowledge about The use of this series of reflective questions rooted in
organizational and provider behavior change. If future this literature will support the effective development,
QI activities are to improve the translation of evidence dissemination, implementation, and review of
into practice, they should be based on an guidelines. "
understanding of the different models and strategies
for implementing research evidence and the evidence Conclusion: "McKeown states: "Medicine must be
base supporting their use. Evidence-based medicine prepared to face the tests which are inescapable in
should be complemented by evidence-based private enterprise and which it is almost unique among
implementation. public activities in having evaded hitherto: Is our work
well done? Is it worth doing? and Does it pay its
THE EVIDENCE FOR DIFFERENT STRATEGIES OF way"40 The process that leads from selecting a topic to
IMPLEMENTING CHANGE: having an impact on patient care is complex and full of
A general framework for changing practice based on potential pitfalls. None the less, there is a growing body
theoretical perspectives and research evidence of research evidence on appropriate approaches. We
considers a variety of theoretical approaches and their have reviewed this literature and produced a series of
contribution to an understanding of provider behavior reflective questions to help incorporate this knowledge
change. The framework summarizes evidence from into practice. We believe that the potential for
systematic reviews of provider behavior change, which guidelines to influence the quality of patient care is
suggest the potential of several dissemination and considerable, particularly when aligned with the process
implementation strategies that are effective under of audit and quality assurance, in the setting of the
certain conditions. Passive dissemination approaches purchaser-provider interaction, and within an overall
are largely ineffective; specific strategies to implement culture of continuous quality improvement. "
research-based recommendations appear to be 6. Haynes RB. Using informatics principles and tools
necessary to ensure practice change. Multifaceted to harness research evidence for patient care:
interventions that address specific barriers to change evidence-based informatics. Medinfo. 1998;9 Pt
are more likely to lead to changes in practice. 1:suppl 33-6.
" Many potentially remediable factors streamlined methods of critical
are responsible for this dilemma in appraisal of research and by
research transfer, including defective centralization of these procedures for
continuing education for health the development of current awareness
professionals and patients; publications and cumulative "best
increasingly complex medical evidence" databases. The Cochrane
regimens; diminishing resources for Collaboration has revolutionized the
health care; and inadequate evidence summarization (systematic review) of
management. The principles and evidence. The internet has provided
procedures of health informatics can access to patients, practitioners, and
help overcome some of these barriers policy makers, alike. Direct-from-
to research transfer, particularly such patient automated data collection
evidence management tasks as promises to move the connection
retrieving, processing, summarizing, between evidence and practice to a
disseminating and applying evidence higher level. In all of these
for clinical care. Evidence retrieval has innovations, health care practice is
been improved by better indexing and most likely to be enhanced by
electronic search engines, by intertwining best evidence with best
improved access from clinical and informatics techniques. "
other settings, and by integration of
evidence into clinical decision support Michie S, Johnston M. Changing
systems. Evidence processing has clinical
been greatly accelerated by
behaviour by making guidelines interventions often involved
specific. BMJ. 2004 Feb complicated procedures and were
7;328(7435):343-5. always an addition to the provision of
guidelines. None of the studies used
"The problems of getting people to act the simplest intervention—that is,
on evidence based guidelines are changing the wording of the
widely recognized. An overview of 41 guidelines. We examine the
systematic reviews found that the importance of precise behavioural
most promising approach was to use a recommendations and suggest how
variety of interventions including audit some current guidelines could be
and feedback, reminders, and improved. ... "
educational outreach. The effective
TRANSLATION OF EVIDENCE
INTO NURSING PRACTICE,

EVIDENCE CLINICAL
PRACTICE GUIDELINES

AND
AUTOMATED
IMPLEMENTATION TOOLS

(IN NURSING INFROMATICS)


Submitted by:

JEVANETTE A. VELACRUZ
JULIE ANN VILLAFLORES MARCIAL N.
MESIAS DE V, RN, MAN

CLINICAL INSTRUCTOR

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