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Immuno Assignment
Immuno Assignment
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What are the differences between endosomal and endogenous pathways of antigen presentation
5
Q.2 What role does preTCR and preBCR have in lymphocyte maturation
The pre-BCR comprises a functionally rearranged IgM heavy chain that pairs with non-polymorphic λ5
and VpreB (also known as VPREB1 or the immunoglobulin ι-chain) components. Pre-BCR signalling
promotes the generation of a large pool of precursor cells that can undergo light-chain gene
rearrangement.