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CHAPTER 10
Study Guide Section 1: Mendelian Genetics

In your textbook, read about how genetics began and the inheritance of traits.
Write the term or phrase that best completes each statement. Use these choices:

cross-pollination dominant gametes inherited

recessive self-fertilization trait

1. Mendel was the first person to succeed in predicting how traits are
from generation to generation.
2. In peas, both male and female sex cells, which are called , are in the
same flower.
3. occurs when a male gamete fuses with a female gamete in the
same flower.
4. Mendel used the technique called to breed one plant with another.
5. Mendel studied only one at a time and analyzed his data
mathematically.
6. In individuals with a heterozygous genotype, the allele of a trait is
hidden by the expression of the other phenotype.
7. In individuals with a heterozygous genotype, the allele of a trait is
visible in the phenotype.
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In your textbook, read about Punnett squares.

Complete the Punnett square by filling in the missing information.

A student crossed true-breeding pea plants that had purple Possible

flowers (P) with true-breeding pea plants that had white gametes 8. p
flowers (p). All of the offspring had purple flowers. Then 10. 11.
the student crossed two plants from the F1 generation. The
student’s Punnett square is shown at right. What information 9.
should the student put in each blank? Remember, the
dominant allele is always written first.
12.
Pp
p

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Study Guide, Section 1: Mendelian Genetics continued

In your textbook, read about the inheritance of traits and Punnett squares.
Use each of the terms below only once to complete the passage.

dihybrid gene genotypes monohybrid phenotypic ratio

A cross between plants that involves one characteristic is called a (13)

cross. Mendel also performed (14) crosses, which involve two
(15) pairs, with pea plants. When he crossed two pea plants that
were heterozygous for both seed shape (Rr) and for seed color (Yy), he observed a 9:3:3:1
(16) among the seeds of the offspring. A Punnett square shows
the possible phenotypes and (17) of the offspring.

Complete the Punnett square by filling in the missing information.

Possible Ry rY
RY ry
gametes
18. 19.
RY RRYY RrYy
round, yellow round, yellow

20. 21. 22. 23.

Ry

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24. 25. 26.
rY RrYy
round, yellow

27. 28. 29. 30.

ry

In your textbook, read about probability.

Refer to the Punnett square above. Respond to the following statement.

31. Find the probability that a wrinkled, green seed will result.

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CHAPTER 10
Study Guide Section 2: Genetic Recombination and Gene Linkage

In your textbook, read about genetic recombination and gene linkage.

Match the definition in Column A with the term in Column B.
Column A Column B

1. genes that are located on the same chromosome A. chromosome map

2. shows the location of several genes B. genetic recombination

3. Drosophila melanogaster C. linked genes

4. an outcome of independent assortment D. fruit fly

For each statement below, write true or false.

5. Crossing over occurs more frequently between genes that are close
together on a chromosome.

6. Gene linkage was first studied by using garden peas.

7. Scientists call a drawing like the one shown above a chromosome map.

8. Chromosome map percentages represent actual chromosome distances.

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In your textbook, read about polyploidy.

Respond to each statement.

9. Recall the name for the occurrence of one or more extra sets of all the chromosomes
in an organism’s cells.

10. State the term for an organism with the chromosome designation 3n.

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CHAPTER 10

Study Guide Section 3: Applied Genetics

In your textbook, read about selective breeding.
Match the definition in Column A with the term in Column B.

Column A Column B

1. the process in which two closely related organisms A. test cross

are bred to produce desired traits and eliminate B. selective breeding
undesired ones in future generations
C. inbreeding
2. the process by which desired traits in an organism
are selected and passed on to their future generations

3. the method for determining the genotype of an organism

In your textbook, read about hybridization.

Complete the graphic organizer about hybridization.

Hybridization
4. Definition:

5. Used by:

6. Advantages of Hybridization: 7. Disadvantages of Hybridization:

Copyright © McGraw-Hill Education

In your textbook, read about inbreeding.
Use each of the terms or phrases below only once to complete the passage.

Clydesdale harmful recessive traits pure breeds recessive allele

Inbreeding may be used to produce (8) . The

(9) horse is a good example of inbreeding. One disadvantage
of inbreeding is that it can lead to (10) . Harmful traits can be
passed on to future generations if both parents carry the (11) .
16 Introduction to Genetics and Patterns of Inheritance CHAPTER 10 Unit 3
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CHAPTER 10
Study Guide Section 4: Basic Patterns of Human Inheritance
In your textbook, read about basic patterns of human inheritance.
Use the terms below to complete the passage. These terms may be used more than once.

albinism alleles cystic fibrosis dominant

heterozygous homozygous pedigree recessive

A (1) shows the inheritance of a particular trait over

several generations. An organism with two of the same (2) for
a particular trait is said to be (3) for that trait. An organism
with two different (4) for a particular trait is heterozygous for
that trait. When alleles are present in the (5) state, the
(6) trait will be observable. An individual who is heterozygous
for a (7) disorder is called a carrier. Examples of recessive
genetic disorders in humans are (8) and
(9) .

In your textbook, read about recessive and dominant genetic disorders.

Complete the table by writing the disease name for each description.

albinism achondroplasia cystic fibrosis

galactosemia Huntington’s disease Tay-Sachs disease

Disease Description
Copyright © McGraw-Hill Education

caused by altered genes; results in lack of skin pigment

10.

recessive genetic disorder; characterized by body’s inability to

tolerate galactose
11.

recessive genetic disorder; gene found on chromosome 15;

characterized by lack of enzyme that breaks down fatty acids
12.
recessive genetic disorder; affects mucus-producing glands,
digestive enzymes, sweat glands
13.
dominant genetic disorder; affects the nervous system
14.
autosomal dominant genetic condition; affects height and
body size
15.

Unit 3 CHAPTER 10 Introduction to Genetics and Patterns of Inheritance 17

Study Guide, Section 4: Basic Patterns of Human Inheritance continued

In your textbook, read about patterns of inheritance.

For each statement below, write true or false.

16. A scientist uses a pedigree to study family history.

17. A pedigree traces the inheritance of a particular trait through only two
generations.

18. In a pedigree, one who does not express the trait is represented by a darkened
square or circle.

19. In a pedigree, a horizontal line between two symbols shows that these indi-
viduals are the parents of the offspring.

20. Individual II1, as shown below, is in generation II.

Refer to the pedigree above. Respond to each statement.

21. Recall if the trait is recessive or dominant based on the following information:
In the pedigree, individuals I1 and I2 are unaffected but have an affected child.

22. Specify if parents II1 and II2, who have an affected child, are carriers of the trait.

Copyright © McGraw-Hill Education

23. Tell whether there is a dominant gene in the genotype of II4.

18 Introduction to Genetics and Patterns of Inheritance CHAPTER 10 Unit 3

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CHAPTER 11
Study Guide Section 5: Complex Patterns of Inheritance

In your textbook, read about incomplete dominance.

Complete the table by checking the correct column(s) for each description.
Reminder: R is dominant (normal red blood cells).
R’ is recessive (sickle-shaped red blood cells).

1. R’R’

2. RR’

3. RR

In your textbook, read about sex-linked traits.

Refer to the Punnett square. Respond to each statement.

XB Y

XB XBXB XBY
Copyright © McGraw-Hill Education

Xb XBXb XbY

Reminder: A female has 2 X chromosomes.

A male has an X and a Y chromosome.
B is dominant (normal color vision).
b is recessive (color blindness).

4. Tell if the father has color blindness.

5. Specify if the father has a recessive allele.

6. State whether the only child that could have color blindness is male or female.

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CHAPTER 11
Study Guide Section 1: DNA: The Genetic Material

In your textbook, read about nucleotides.

Label the diagrams of DNA nucleotides and bases. Use these choices:

cytosine guanine phosphate purine pyrimidine sugar

1.

2.

3.

4.

5.

6.

In your textbook, read about DNA structure.

Write the term or phrase that best completes each statement. Use these choices:

adenine (A) chromosome cytosine double helix

double-ring genetic material nitrogenous bases nucleic acids
nucleotides purine single-ring
Copyright © McGraw-Hill Education

7. , guanine (G), cytosine (C), and thymine (T)

are the four in DNA.

8. In DNA, always forms hydrogen bonds with

guanine (G).
9. The sequence of carries the genetic information
of an organism.
10. Chargaff’s data states that the number of bases
equals the number of pyrimidine bases in DNA.
11. The twisted ladder shape of DNA is called a .
12. DNA is the of all organisms.
13. The pyrimidine bases have a structure.
14. The purine bases have a structure.
15. DNA and RNA are the two found in living cells.
16. DNA supercoils to make up the structure known as a .

Unit 3 CHAPTER 11 Molecular Genetics 85

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CHAPTER 11
Study Guide Section 2: Replication of DNA

In your textbook, read about semiconservative replication.

Match the description in Column A with the term in Column B.
Column A Column B

1. unwinds in multiple areas as DNA is replicated A. semiconservative replication

2. parental strands separate and serve as templates B. DNA helicase

for new strands of DNA
C. single-stranded binding
3. the DNA of prokaryotes proteins

4. keep the strands of DNA separate during D. leading strand

replication
E. eukaryotic DNA
5. elongates as DNA unwinds and is replicated
continuously F. circular DNA

6. unwinds the double helix

In your textbook, read about base pairing.

Label the diagram showing DNA replication. Use these choices:

DNA ligase DNA polymerase leading strand Okazaki fragments parental DNA

Copyright © McGraw-Hill Education

7. 10.
8. 11.
9. 12.

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CHAPTER 11
Study Guide Section 3: DNA, RNA, and Protein

In your textbook, read about the central dogma of biology.

For each statement below, write true or false.

1. The central dogma of biology, or the mechanism of reading and

expressing genes in all living things, can be expressed as follows:
DNA → RNA → proteins.

2. The process of the synthesis of mRNA from DNA is called translation.

In your textbook, read about the code.

Refer to the figure. Respond to each statement.

3. Express the following sequence of DNA nucleotides as compli-

mentary mRNA codons.
TACCGATTAACAACT

4. Write the specific amino acid or code that each mRNA codon
from statement 3 above represents.

5. Identify the start and stop mRNA codons.

Copyright © McGraw-Hill Education

In your textbook, read about translation and the role of the ribosome.
Use each of the terms below only once to complete the passage.

anticodon cytoplasm mRNA protein

ribosome start codon translation tRNA

Once the (6) is synthesized, it leaves the nucleus and

enters the (7) . The 5' end of the mRNA connects to the
(8) , where the code is read and translated to make a(n)
(9) in a process called (10) . In
translation, (11) interprets the mRNA codon sequence. Once the mRNA
is associated with the ribosome, a tRNA with the (12) CAU will bind to
the mRNA (13) AUG.

Unit 3 CHAPTER 11 Molecular Genetics 87

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CHAPTER 11
Study Guide Cellular Reproduction and Sexual Reproduction
Study Guide Section 4: Gene Regulation and Mutations

In your textbook, read about prokaryote and eukaryote gene regulation.

If the statement is true, write true. If the statement is false, replace the italicized term or
phrase to make it true.
1. Gene regulation is the ability of an organism to control which genes are transcribed.

2. A chromosome contains the genes for the proteins needed for a specific metabolic
pathway.

3. An operator is a segment of DNA that acts as an on/off switch for translation.

4. Eukaryotes can control gene expression using transcription factors.

5. Hox genes play an important role in determining the gender of an organism.

In your textbook, read about mutations.

Refer to the figure below. Respond to the following statement.

Copyright © McGraw-Hill Education

6. Record the mRNA codon sequence that would result from a substitution mutation
of A instead of G in the amino acid alanine (Ala) in the above protein.

Complete the table by filling in the missing information. Use these choices:

frameshift substitution

mRNA Sequence Mutation Sequence Type of Mutation

7. UGU-CCG-GAA-CGA UGC-CGG-GAA-CGA

8. GAA-CGU-AGC-GGU GAU-CGU-AGC-GGU

9. UGU-UUC-CCU-UAA
Chapter ResourcesUGU-UCC-CUU-AA*
• Cellular Reproduction and Sexual Reproduction
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Study Guide Cellular Reproduction and Sexual Reproduction

In your textbook, read about the cell cycle.
Draw the cell cycle in the space below. Include the following labels:
cytokinesis, G1, G2, interphase, mitosis, S.
1.

Match the definition in Column A with the term in Column B.

Column A Column B
2. stage in which the cell divides into two daughter cells with A. S phase
identical nuclei
B. cytokinesis
3. substage of interphase immediately after a cell divides
C. G1
4. substage of interphase in which the cell copies its DNA
in preparation for cell division
D. G2
5. stage in which the cell’s nuclear material divides and separates
E. interphase
6. main stage in which the cell grows, carries out normal functions,
and duplicates its DNA F. mitosis

7. substage in which the cell prepares for nuclear division and a

protein that makes microtubles for cell division is synthesized

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Study Guide Cellular Reproduction and Sexual Reproduction

In your textbook, read about the stages of mitosis.

For each statement below, write true or false.
1. The nuclear membrane disintegrates during prophase.
2. Microtubules move chromatids to the poles of the cell during anaphase.
3. Chromosomes reach the poles of the cell during metaphase.
4. The cell’s chromatin condenses into chromosomes during prophase.
5. The nuclear envelope re-forms during anaphase.
6. Chromosomes attach to spindle fibers and line up along the equator of the
cell during metaphase.
7. The nucleus reappears during prophase.
8. Centrioles migrate to the poles of the cell during telophase.
9. Chromatids are pulled apart during anaphase.
10. The first stage of mitosis is telophase.
11. The chromosomes decondense or unwind during telophase.
12. One of the shortest stages of mitosis is metaphase.

Label the diagram of the stages of mitosis using lines 13–16. Use these choices:

anaphase metaphase prophase telophase

Label the diagrams above using lines 17–20. Use these choices:

centrioles centromere sister chromatids spindle fibers

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Study Guide Cellular Reproduction and Sexual Reproduction

In your textbook, read about the abnormal cell cycle and cancer.
Complete the graphic organizer about the causes and prevention of cancer. These terms may be
used more than once: carcinogens, cell cycle, cells, DNA damage, genetic changes, spindle
fiber failure, the Sun’s ultraviolet rays, tobacco.

Cancer

is the uncontrolled
growth and division of
1.

that is often prevented by that is caused by

cell-cycle checkpoints unrepaired exposure to

2.
that monitor for

3.
or 4. 5.

and stop the such as

6. 7. 8.

before
excessive X rays
cytokinesis

Complete the table by checking the correct column for each description.
Description Apoptosis Stem Cells
9. After a sperm fertilizes an egg, the resulting mass of cells divides until
there are about 100 to 150 cells.
10. Some cells go through a programmed death.
11. Embryonic cells shrivel and die, resulting in the formation of fingers and
toes.
12. Unspecialized cells are either embryonic or adult.
13. This event occurs in cells that are damaged beyond repair.

Chapter Resources • Cellular Reproduction and Sexual Reproduction

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Study Guide Cellular Reproduction and Sexual Reproduction

In your textbook, read about meiosis I and meiosis II.

Label the diagrams below. Use these choices:

anaphase I anaphase II interphase metaphase I metaphase II

prophase I prophase II telophase I telophase II

1. 2. 3. 4. 5.

6. 7. 8. 9.

Complete the table by checking the correct column(s) for each description.

Description Mitosis Meiosis

10. Involved in the production of gametes

11. Involved in growth and repair

12. Promotes genetic variation in organisms

13. Consists of one nuclear division

14. Produces daughter cells that are genetically identical

15. Involves two sets of nuclear divisions

16. Produces daughter cells that are not identical

17. Involves the synapsis of homologous chromosomes

18. Occurs during asexual reproduction

19. Results in four haploid gametes

20. Also called reduction division

Chapter Resources • Cellular Reproduction and Sexual Reproduction

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Study Guide Cellular Reproduction and Sexual Reproduction

In your textbook, read about chromosomes and human heredity.

Match the definition in Column A with the term in Column B.
Column A Column B
1. micrograph of chromosomes A. karyotype

2. abnormal number of chromosomes B. Down syndrome

3. extra chromosome 21 C. telomere

4. protective cap at the end of a chromosome D. nondisjunction

In your textbook, read about Down syndrome.

Draw the indicated parts of a karyotype of a child born with Down
syndrome and respond to each statement.

5. Chromosome 20 6. Chromosome 21 7. Chromosome

22
9. Tell why this karyotype is called “trisomy.”

10. Recall the term for the sister chromosomes failing to separate during cell division.

11. State whether the risk of having a child with Down

syndrome is higher in mothers who are younger or older.

Chapter Resources • Cellular Reproduction and Sexual Reproduction

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