Name Mechanism of Action Indication Side Effects Nursing Considerations

Trimetazidine inhibits β-oxidation This drug is recommended in Dizziness, headache, abdominal  Check for doctor’s
Generic Name: of fatty acids through inhibition of long term treatment of coronary pain, dyspepsia, diarrhoea, order
Trimetazidine long-chain 3-ketoacyl-CoA insufficiency; Angina Pectoris nausea, vomiting, pruritus, rash,  2 Monitor blood
thiolase, which enhances glucose urticaria, asthenia pressure and pulse
Bnd Name: oxidation. It ensures proper rate before and
Vastarel functioning of ionic pumps and after giving the meds.
transmembrane Na-K flow by Contraindications
 Notify prescribing
Classification: preventing decrease in
Anti Angina intracellular ATP levels. Parkinson's disease, Adverse Effects signs of heart failure
parkinsonian symptoms, tremors, such as swelling
Dosage: 35 mg restless leg syndrome and other of hands and feet or
movement related disorders. Tachycardia, palpitations, SOB.
Frequency: BID Severe renal impairment (CrCl extrasystoles, orthostatic  Advise patient of the
<30 mL/min). Lactation. hypotension, arterial hypotension, adverse effects of the
Route: Po flushing.. drug.