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AJPH RESEARCH

Culturally Responsive Adolescent Pregnancy and


Sexually Transmitted Infection Prevention
Program for Middle School Students in Hawai‘i
Yasuyo Abe, PhD, Linda Toms Barker, MA, Vincent Chan, BA, and Jasmine Eucogco, MPP, MPH

Objectives. To evaluate the effectiveness of Pono Choices, a culturally responsive curriculum. (See Appendix A, available as a
adolescent pregnancy and sexually transmitted infection (STI) prevention program supplement to the online version of this article
targeting middle school youths in Hawai‘i. at http://www.ajph.org, for information on
Methods. We conducted a cluster randomized controlled trial with the school as the unit how the intervention reflects Hawaiian culture.)
of random assignment over 3 semesters between 2012 and 2013. The sample consisted of
Research has suggested that indigenous culture–
based educational strategies can be an effective
36 middle schools and 2203 students. We administered student surveys to collect baseline
alternative to mainstream strategies in addressing
outcomes, student demographic data, and outcomes at 12 months after baseline.
the needs of non-White students.6–8 A study of
Results. We found statistically significant effects for the knowledge assessment, which
high school students in Hawai‘i, 73% of
focused on basic understanding of adolescent pregnancy and STI prevention. The av- whom are non-White, linked their academic
erage percentage of correct responses was 73.6 for the treatment group and 60.4 for the outcomes to the use of culturally responsive
control group (P < .001). We did not find statistically significant effects on behavioral education.9 Another study suggested that
outcomes (initiation of sexual activity or engagement in high-risk sexual behavior) or on Hawaiian students taught with an emphasis on
other nonbehavioral outcomes (attitudes, skills, intentions). native culture had a strengthened sense of
Conclusions. Pono Choices had a statistically significant impact on knowledge of connection to ancestors and an increased desire
adolescent pregnancy and STI prevention among middle school students at 12 months to learn.10 These studies support Pono Choices’
after baseline, though it did not lead to detectable changes in behavioral outcomes focus on Hawaiian culture as a promising
within the 1-year observation period. These results call for an exploration of longer-term approach to engaging youths in the state.
outcomes to assess effects on knowledge retention and behavioral changes. (Am J Public In addition to being culturally responsive,
Pono Choices was designed as a middle school
Health. 2016;106:S110–S116. doi:10.2105/AJPH.2016.303395)
intervention. Research has indicated that sexual
health interventions should start in early ado-
See editorials, p. S5–S31. lescence, particularly for youths from disadvan-
taged or dysfunctional families.11 Research has

H awaiian high school students had the developed the Pono Choices curriculum, also suggested that the best way to prevent the
lowest rate of condom use in the which seeks to provide adolescents with the high-risk behaviors that often precede sexual
United States in 2011 (43.9%, compared medically accurate knowledge, attitudes, activity is to work with young adolescents.11,12
with 60.2% nationwide)1 and the 10th The theory of change underpinning this
and skills necessary to reduce the risk of
highest adolescent pregnancy rate in 2010 study predicts that youths exposed to Pono
sexually transmitted infection (STI) and
(6.5%, compared with 5.7% nationwide).2 Choices will improve their knowledge,
unintended pregnancy. Pono Choices was
Furthermore, in this racially diverse state,3 attitudes, skills, and intentions toward pregnancy
designed exclusively for youths in Hawai‘i, and STI prevention, which will then lead to
female minorities are at disproportionately emphasizing the values and practices of the host delayed initiation of sex and fewer risky be-
high risk for adolescent births (29 per 1000 culture to promote pono (right) choices. For haviors in later years. To assess the impact of
among Asian/Pacific Islanders aged 15 to 19
example, it uses native language and indigenous Pono Choices, we conducted a cluster ran-
years, compared with 22 per 1000 among
stories and emphasizes the active involvement domized controlled trial. Because the ultimate
their White counterparts in 2012).4 The
of family in discussing key components of the goal of the intervention was to affect youths’
state’s chlamydia rate has consistently been
higher than the national average over the
previous decade (2001–2010) and only re- ABOUT THE AUTHORS
Yasuyo Abe, Linda Toms Barker, and Vincent Chan are with IMPAQ International, LLC, Oakland, CA. Jasmine Eucogco is
cently improved.5 Responding to the need with athenahealth, Inc., Watertown, MA.
for effective sexual health education cur- Correspondence should be sent to Yasuyo Abe, IMPAQ International, LLC, 1333 Broadway, Suite 300, Oakland, CA 94612
(e-mail: yabe@impaqint.com). Reprints can be ordered at http://www.ajph.org by clicking the “Reprints” link.
ricula in the state, the University of Hawai9i This article was accepted July 16, 2016.
at Manoa, with Hawai‘i-based partners, doi: 10.2105/AJPH.2016.303395

S110 Research Peer Reviewed Abe et al. AJPH Supplement 1, 2016, Vol 106, No. S1
AJPH RESEARCH

sexual activity, we assessed impacts on 2 be- however, because we found that the planned returning the forms. In addition to parental
havioral outcomes—initiation of sex and en- timing did not necessarily translate to the actual consent, we obtained student assent at the
gagement in high-risk sexual behaviors—even timing of the health curriculum. time of baseline data collection.
though observable changes in these outcomes Random assignment was carried out using Overall, 2203 students (1383 intervention
were expected to be small among middle computer-programmed protocols based on students, 820 control students) in the 34
schoolers because of their young age. We also randomized sequencing and allocation of participating schools were enrolled in
explored nonbehavioral outcomes on which we schools. A methodologist on the evaluation study-eligible health classes during the
expected the intervention would have more team oversaw the process, witnessed by an- implementation period. The smaller size of
immediate effects among young adolescents. All other senior researcher not associated with the control group is attributable to random-
our questions focused on measures of impact the project. The assignment yielded 18 in- ization, which resulted in intervention
among youths at 12 months after baseline, tervention and 18 control schools. Immedi- schools, on average, having larger class sizes
namely, what was the impact of Pono Choices on ately after randomization, however, 1 public and offering more health classes. Of 2203
charter intervention school and 1 regular study-eligible students, we obtained parental
d initiation of sexual activity? public control school—despite prior com- consent for 81%, or 1783 students (1158
d engagement in high-risk sexual behaviors? mitment to participate—dropped out, de- intervention students, 625 control students).
d knowledge of pregnancy and STI clined any further contact, and provided no We administered the student baseline
prevention? additional information. The impact analyses survey on the first day of the sexual health
d attitudes toward healthy sexual behaviors? were based on the data collected from stu- instruction and the follow-up survey at 12
d skills in managing relationships and dents in the remaining 34 schools. months after baseline at participating schools.
choices? The implementation period for round 1 Both surveys included items on students’
d intentions about future sexual activity? schools covered 3 semesters (which we refer sexual behaviors, knowledge, skills, attitudes,
to as 3 semester cohorts of students) from and intentions. The baseline survey also col-
spring 2012 to spring 2013. For round 2 lected information on students’ demographic
schools, only 2 semester cohorts were backgrounds. The paper-and-pencil surveys
METHODS included—fall 2012 and spring 2013. The were collected in person in group adminis-
Middle schools in Hawai‘i implementing schools offered sexual health instruction as trations. When students could not participate
the state sexual health standards for seventh and part of a semester-long health class, but not all in group administration, individual surveys
eighth grade were eligible to participate in the schools offered a health class every semester. were administered by mail with telephone,
study. Participation required that the school All seventh and eighth graders enrolled in e-mail, and repeat mail follow-ups. Of the
commit to random assignment to either the a health class taught by a participating health 1783 students with parental consent, 1735
intervention or the control group and identify education teacher during the implementation (1135 intervention students, 600 control stu-
1 health education teacher who agreed to period were eligible to participate in the dents) took the baseline survey and 1548 (997
cooperate in the study. Schools were recruited study if they had prior parental consent. If intervention students, 551 controls) took the
in 2 rounds—in fall 2011 and in spring 2012— a teacher instructed more than 2 health classes follow-up survey (Figure A, available as
from the islands of O‘ahu, Hawai‘i Maui, in a semester, the first 2 classes in which the a supplement to the online version of this
Moloka‘i and Kaua‘i. Overall, 36 schools were sexual health curriculum was taught were article). Table 1 summarizes the characteristics
recruited (19 in round 1 and 17 in round 2), selected for the study. Depending on when the of the students participating in the study.
including 21 regular public schools, 14 public school was recruited and how often it offered In addition to collecting student data, we
charter schools, and 1 private school. a sexual health class, classes from as many as 3 conducted classroom observations of randomly
Round 1 schools recruited during fall 2011 semesters per school were included in the selected Pono Choices lessons (22% of total
were randomly assigned in November 2011, study. The schools were assigned once, and lessons delivered) to assess the implementation
before the start of the spring 2012 semester students were exposed to either Pono Choices of the intervention. These observations were
when the implementation period began. or business-as-usual sexual health instruction conducted by trained members of our
Round 2 schools were recruited during spring according to their school’s initial assignment. evaluation team. We also obtained information
2012 and randomly assigned in May 2012, Parental consent was collected for students on the sexual health curricula implemented in
before implementation in the fall 2012 se- enrolled in all study classes in intervention and the control group from teacher interviews
mester. Schools were blocked in terms of island control schools at the start of each semester. conducted by the implementation team.
(O‘ahu, which has a large urban area with 75% To eliminate potential influence of the as-
of the state’s population, vs neighbor islands) signment on parents’ decision, we obtained
and type of school (regular public vs public their consent before they were informed Intervention and Control
charter or private). In addition, timing of about the curriculum used in their child’s Conditions
planned implementation of the health cur- class. The consent form made no reference to Pono Choices focused on developing the
riculum (early vs later in the semester) was used the specific curriculum. When teachers knowledge, attitudes, and skills of middle
to block schools in round 1. The timing of hosted a parent meeting to explain the cur- schoolers. Knowledge development empha-
implementation was not used in round 2, riculum, they did so after the due date for sized information on reproductive health and

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TABLE 1—Student Characteristics at Baseline: Hawai‘i, 2012-2013

Characteristic No. Observationsa Intervention, Mean (SD) Control, Mean (SD) Difference in Group Mean
Age, y 1455 12.27 (0.64) 12.28 (0.60) –0.01
Seventh grader 1473 0.90 (0.30) 0.86 (0.35) 0.04
Female 1464 0.53 (0.50) 0.55 (0.50) –0.02
Bisexual or homosexual 1448 0.03 (0.16) 0.02 (0.14) 0.01
Student uses non-English language at home 1484 0.26 (0.44) 0.39 (0.49) –0.12**
Parent does not speak English 1470 0.02 (0.13) 0.02 (0.14) –0.01
Received mostly As and Bs for grade 1393 0.72 (0.45) 0.71 (0.45) 0.01
b
Native Hawaiian 1467 0.42 (0.49) 0.49 (0.50) –0.08
Asianc 1467 0.71 (0.45) 0.74 (0.44) –0.03*

Note. Test of significance takes into account clustering effects. All characteristic indicators are binary, except for age, which is measured in years.
a
Non-missing responses.
b
Includes those who reported to be Native Hawaiian, irrespective of other reported race/ethnicity.
c
Includes those who reported to be Asian, irrespective of other reported race/ethnicity.
*Significant at the .05 level.
**Significant at the .01 level.

pregnancy prevention methods and on the approved curricula. Schools could choose term. For the estimation of continuous out-
causes, transmission, and prevention of STIs. which and how much of the material they comes, we applied the restricted maximum-
Attitude development addressed beliefs and used and who would teach it. likelihood method assuming the normal
opinions about abstinence, STIs, and preg- distribution for an individual error term.
nancy. Skills development focused on nego- Besides study design controls (blocking and
Outcome Measures semester cohort) and the baseline outcome, the
tiation and refusal skills, correct condom use,
Table 2 describes student outcome mea-
and improved self-efficacy. All content was estimated model included the following
sures constructed from the survey. A psy-
delivered with an emphasis on Hawaiian covariates measured at baseline: percentage of
chometric evaluation was conducted to
cultural values and using Hawaiian language, students in the school eligible for free or
review items on knowledge, attitudes, and
stories, and practices. The curriculum included reduced-price meal; student age, gender, race
skills to ensure that the composite scales met
9.5 hours of content divided into 10 sequential (self-identifying as Asian and as Native Ha-
or exceeded the reliability (Cronbach’s alpha)
modules. The basic delivery model assumed waiian), and academic performance; and an
of 0.50 for internal consistency. Because
10 continuous sessions (1 module per session) indicator of whether the student did not speak
the composite scale for intention did not meet
over part of a semester, but the contents could English at home. Covariates were used to
the threshold, the 2 intention items were
be delivered in fewer or more sessions. improve impact estimates and were not
analyzed as separate measures.
Pono Choices was designed as a scripted assessed for their effects. We chose the cova-
curriculum to accommodate varying teacher riates from a list of available indicators po-
knowledge and skill levels. All intervention tentially correlated with the behavioral
Impact Estimation Models
group teachers were trained in a 2-day work- outcomes if they empirically explained the
For each outcome, the program impact was
shop to use the instructional manual and pro- variation in the outcome or if the baseline
estimated as the group difference at 12 months
gram kit. In addition, all intervention group equivalence was not established. We applied
after baseline. The impact was estimated as
teachers received ongoing support, including the listwise deletion method to handle missing
intent-to-treat effects, including all study-
observation and feedback from instructional outcome data and used the dummy variable
eligible students with data, regardless of the
coaches and a 1-day refresher training each adjustment method for missing covariate data
level of participation. (Appendix B, available as
semester. Additional information on the in- (missing data were replaced by a constant value
a supplement to the online version of this ar-
tervention is provided in the final study report.13 and flagged by a dummy indicator).
ticle, provides details on the estimation models.)
The control condition was business- To account for the effects of clustering
as-usual sexual health instruction in regular of individuals within each school and to
seventh- and eighth-grade health classes. The improve the precision of impact estimates, we
state had not adopted a standard health cur- specified a mixed-level model. For the esti- RESULTS
riculum across schools but required sexual mation of binary outcomes, we applied the The implementation data indicate that
health instruction that was age appropriate maximum-likelihood method assuming Pono Choices was delivered with high ad-
and medically accurate and provided a list of the logit distribution for an individual error herence to the intended intervention model.

S112 Research Peer Reviewed Abe et al. AJPH Supplement 1, 2016, Vol 106, No. S1
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TABLE 2—Behavioral and Nonbehavioral Outcome Measures

Outcome Description of Outcome


Behavioral outcome
Initiation of sexual activity Responded “yes” to the question “Have you ever had sexual intercourse?”
Engagement in high-risk sexual behaviors Responded “yes” to both of the following questions:
d In the past 3 months have you had sexual intercourse without a condom?
d In the past 3 months have you had sexual intercourse without an effective method of birth control—including condoms, birth
control pills, the shot (Depo Provera), the patch, the ring (NuvaRing), IUD (Mirena or Paragard), implant (Implanon)?
Nonbehavioral outcomes
Knowledge of pregnancy and STI prevention Weighted average of the following:
d Percentage of 9 multiple-choice questions that respondents answered correctly regarding pregnancy and STI prevention topics
(excluding knowledge of condom use): (1) effective ways to prevent pregnancy, (2) behaviors associated with high risk of HIV,
(3) definition of viral STIs, (4) signs of STI in another person, (5) process of reproduction, (6) prevention methods for STIs,
(7) refusal skills, (8) transmission mechanism of HIV, and (9) types of birth control.
d Percentage of 9 multiple-choice questions that respondents answered correctly regarding knowledge of condom use: (1)
condom usage, (2) wearing 2 condoms, (3) how far unrolled, (4) no space at tip of condom, (5) unrolling wrong way, (6)
expiration date, (7) removal of condom, (8) lubricants, and (9) wallet as storage.
Attitudes toward healthy sexual behaviors Average rating of 10 items on 4-point scale (ranging from 1 = not important to 4 = very important) on the importance of healthy
sexual behaviors.
d The 10 items are (1) not having sex until ready, (2) avoiding risky sexual behavior, (3) preventing unwanted pregnancy as an
adolescent, (4) knowing what birth control methods can be used to prevent an unwanted pregnancy, (5) taking personal
responsibility for sexual health, (6) communicating openly about sexual intent with a partner, (7) knowing multiple ways to
prevent STIs and unwanted pregnancy, (8) using condoms to prevent STIs and unwanted pregnancy, (9) using alternative ways
to show affection other than having sex, and (10) understanding changes that happen during puberty.
d The reliability score was a = .86 at baseline and a = .88 at 12 months after baseline.
Skills in managing relationships and choices Average rating of 5 items on a 4-point scale (ranging from 1 = very difficult to 4 = very easy) on difficulty of skills relate to
managing relationship and choices.
d The 5 items are (1) effectively communicating with my partner about my intentions and wishes about sexual activity, (2)
refusing unwanted and/or unprotected sex, (3) identifying if a relationship is healthy or unhealthy, (4) following the steps for
correct condom use, and (5) getting/buying condoms or other birth control.
d The reliability score was a = .66 at baseline and a = .66 at 12 months after baseline.
Intention to have sex Response on 4-point scale (ranging from 1 = definite intention to 4 = no intention) to the question “Do you intend to have sexual
intercourse in the next 12 months?”
Intention to use condom during intercourse Response on 4-point scale (ranging from 1 = no intention to 4 = definite intention) to the question “If you were to have sexual
intercourse in the next 12 mo, would you intend to use (or have your partner use) a condom?”

Note. IUD = intrauterine device; STI = sexually transmitted infection.

Teachers completed 98% of planned activities The contents of the sexual health cur- sessions of sexual health instruction; others
across all 3 semesters. From attendance ricula in control schools overlapped with provided as many as 10. Only 2 control
records, we estimated that 94% of students Pono Choices to a varying degree. Each of schools fully implemented an approved sexual
completed at least 75% of the curriculum. 4 key topics covered by Pono Choices— health curriculum.
The classroom observation data that our reproductive anatomy, pregnancy pre-
evaluation team members collected also vention, STI prevention, and refusal skills—
suggest that the quality of the activities was included in the majority (9–12 of 17) Baseline Equivalence of Analytic
completed was high: The average observer of control group sexual health programs. Samples
ratings for quality of delivery and student However, the fifth key component, the We report impact findings based on 2
engagement were 4.3 and 4.6, re- condom demonstration, was included at only analytic samples: 1 used for behavioral out-
spectively, on a scale ranging from 1 to 5, 5 of the 17 control schools. The imple- come analyses, consisting of students with no
with 5 being excellent (Table A, available mentation of control group curricula was less missing behavioral outcome data (955 in-
as a supplement to the online version of extensive and uniform than Pono Choices. tervention students, 529 control students),
this article). Some control schools provided only 1 or 2 and 1 used for nonbehavioral outcome

Supplement 1, 2016, Vol 106, No. S1 AJPH Abe et al. Peer Reviewed Research S113
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analyses, consisting of students with no nonbehavioral outcomes. The intervention covariate specifications, and alternative
missing nonbehavioral outcome data had no statistically significant effects on be- estimation methods. In addition, to check
(819 intervention students, 381 control havioral outcomes at 12 months after baseline. for potential bias resulting from school at-
students). We evaluated whether these ana- The estimated probability of engaging in trition, we conducted impact analyses
lytic samples were equivalent across the high-risk sexual behaviors was 1.5% for the based on an alternative sample excluding all
groups with respect to baseline outcome intervention group and 2.2% for the control schools that were in the same assignment
measures and other school and student char- group. The difference—the estimated impact blocks as the 2 dropped schools. This alternative
acteristics (Table B, available as a supplement to of Pono Choices—was not statistically signif- sample of 31 schools was balanced across the
the online version of this article). The icant (P = .42). Similarly, the estimated prob- assignment conditions regarding observable
student-level group difference was evaluated ability of ever having had sex at 12 months after criteria used to block the schools. The analyses
using the same statistical model used to esti- baseline was 9.6% for both the intervention yielded consistent results, showing no statisti-
mate the impacts, except only assignment group and the control group (for unadjusted cally significant effects on any outcomes except
group and blocking variables were used as outcomes, see Table C, available as a supple- the knowledge measures (Table D, available
controls. Outcomes measured at baseline were ment to the online version of this article). as a supplement to the online version of this
equivalent across the groups except for dif- The intervention had a statistically significant article). Sensitivity analyses conducted on the
ferences in attitudes toward healthy sexual impact on student knowledge at 12 months after knowledge measures showed that the result was
behaviors and intent to use condoms in the baseline. On average, the intervention group robust across alternative technical specifications
future (Table 3). Additional equivalence tests students answered 73.6% of knowledge ques- and estimation methods as well as with the
(not shown) found that indicators for whether tions correctly, and the control group answered 31-school alternative sample.
the student spoke English at home and iden- 60.4% correctly. The difference between the
tified as Asian were not equivalent. The groups (13.2 percentage points) was statistically
nonequivalent indicators were included as significant (P < .001). By contrast, we did not
covariates in the impact estimation. find statistically significant impacts on measures DISCUSSION
of attitudes, skills, or intentions. The purpose of the study was to evaluate
To check the robustness of the results, the effectiveness of Pono Choices, a culturally
Impact Findings we conducted sensitivity analyses, including responsive adolescent pregnancy and STI
Table 4 reports the regression-adjusted the application of an alternative method prevention program targeting middle-school
estimated effects for behavioral and to address missing covariates, alternative youths in Hawai‘i. The study focused on the

TABLE 3—Summary Statistics for Baseline Outcomes: Hawai‘i, 2012-2013

Baseline Outcome Intervention, Mean (SD) Control, Mean (SD) Difference P for Difference No.
Behavioral outcomes
a
Initiation of sexual activity 0.064 (0.246) 0.071 (0.256) –0.006 .95 1262
Engagement in high-risk sexual behaviorsb 0.007 (0.084) 0.002 (0.047) 0.005 .21 1287
Nonbehavioral outcomes
Knowledge of pregnancy and STI preventionc 62.9 (18.9) 61.4 (20.6) 1.5 .54 1173
d
Attitudes toward healthy sexual behaviors 3.45 (0.49) 3.38 (0.56) 0.06 .028 1172
e
Skills in managing relationships and choices 2.79 (0.56) 2.81 (0.58) –0.02 .86 1157
Intention to have sexf 3.38 (0.81) 3.36 (0.84) 0.03 .75 1136
Intention to use condom during intercourseg 3.60 (0.76) 3.50 (0.89) 0.09 .011 1122

Note. Test of significance takes into account clustering effects. The size of the behavioral analytic sample was 1484, and the size of the nonbehavioral analytic
sample was 1200. Equivalence tests were conducted using nonmissing observations of baseline variables. Assignment group and blocking variables were
included as controls. In the impact estimation, the dummy variable adjustment method was used for missing baseline variables as covariates.
a
A binary indicator (1 = ever had sexual intercourse and 0 = otherwise).
b
A binary indicator (1 = used neither condom nor birth control when having sex and 0 = otherwise).
c
Weighted average of percentage of correct responses to 9 questions regarding pregnancy and STI prevention topics and percentage of correct responses to
9 questions regarding condom use.
d
Average rating of 10 items on 4-point scale (ranging from 1 = not important to 4 = very important) on the importance of healthy sexual behaviors.
e
Average rating of 5 items on a 4-point scale (ranging from 1 = very difficult to 4 = very easy) on difficulty of skills related to managing relationship and choices.
f
Response on 4-point scale (ranging from 1 = definite intention to 4 = no intention) to the question “Do you intend to have sexual intercourse in the next
12 months?”
g
Response on 4-point scale (ranging from 1 = no intention to 4 = definite intention) to the question “If you were to have sexual intercourse in the next
12 months, would you intend to use (or have your partner use) a condom?”

S114 Research Peer Reviewed Abe et al. AJPH Supplement 1, 2016, Vol 106, No. S1
AJPH RESEARCH

impact at 12 months after baseline to in- ever had sex by eighth grade.14 In our partly attributable to measurement limita-
vestigate early responses among youths to the sample, the unadjusted percentage of tions. These nonbehavioral measures—the
intervention. Impact analyses found mixed control group students having ever had sex average of 4-point scale ratings—may not
results across measures, with no impacts on increased by just 2 percentage points, from have been adequate to capture the group
behavioral measures and most nonbehavioral 9% at baseline to 11% at 12 months after difference. The unadjusted control group
measures, but with a sizable and statistically baseline, which underscores the challenge means of the average ratings on attitudes, skills,
significant impact on student knowledge. of detecting a program impact that is likely and intentions at baseline ranged from 3.0 to
Given the implementation findings, the to be small. 3.7, with 4.0 being the highest, leaving little
failure to observe impacts on most outcomes On the other hand, we found a statistically room for the rating to improve.
was unlikely to have been driven by poor significant impact on student knowledge, which The study has several important limitations,
implementation of the intervention. Al- covered topics such as effective pregnancy including that its findings cannot be general-
though the failure to detect impacts across prevention methods and mechanisms of STI ized because the schools were purposively
behavioral outcome measures may indicate transmission. Given the constraint on detecting selected on the basis of their willingness to
that Pono Choices was not effective, it may impacts on behavioral outcomes, observed participate and administrative support for the
also be attributable to the short follow-up impacts on knowledge provide an important study. Another limitation arises from the de-
period. Because of the relatively young indication of the intervention’s potential effects. sign. As with most studies in school settings,
average age (12 years) of the students at Previous studies have identified or suggested randomization for this study was done before
baseline, we anticipated that the follow-up that knowledge is a protective or mediating we could identify study-eligible students. To
at 12 months after baseline might be too factor leading to behavior changes.15–23 make individual-level inferences, we assumed
early to observe changes in sexual behav- Thus our finding of a positive impact on that enrollment in study schools was in-
iors, because most students were not yet knowledge, which was considered to be dependent of assignment and that parents
sexually active. Impacts on behavioral a proximal outcome, is not inconsistent with consented without knowledge of assignment
outcomes, if any, were expected to be small. finding no impact on more distal behavioral status. These assumptions, however, are not
For example, the Centers for Disease outcomes. verifiable. The study also had attrition at both
Control and Prevention reported that in Failure to detect effects on nonbehavioral school and student levels, which could lead to
2013, only 10% of youths in Hawai‘i had outcomes other than knowledge may be bias in the impact estimates. Although sensitivity

TABLE 4—Estimated Impacts of Pono Choices on Behavioral and Nonbehavioral Measures at 12 Months After Baseline: Hawai‘i, 2013-2014

Outcome Intervention Group, Mean Control Group, Mean Difference (SE) P for Difference
Behavioral outcomes (n = 1484)
Engagement in high-risk sexual behaviorsa 0.015 0.022 –0.007 (0.0091) .42
b
Initiation of sexual activity 0.096 0.096 0.000 (0.0167) .99
Nonbehavioral outcomes (n = 1200)
Knowledge of pregnancy and STI preventionc 73.6 60.4 13.2 (2.07) < .001
Attitudes toward healthy sexual behaviorsd 3.61 3.61 0.00 (0.037) .99
e
Skills in managing relationships and choices 3.00 2.97 0.03 (0.039) .42
f
Intention to have sex 3.30 3.25 0.05 (0.091) .56
Intention to use condom during intercourseg 3.71 3.73 –0.02 (0.043) .56

Note. STI = sexually transmitted infection. The knowledge measure was statistically significant after adjusting for multiple comparisons. The measure remained
statistically significant using either the Benjamini and Hochberg method or the Bonferroni method to adjust for 5 comparisons under the nonbehavioral
outcome domain. The measure also remained statistically significant using either method to adjust for 7 comparisons across behavioral and nonbehavioral
outcome domains.
a
A binary indicator (1 = ever had sexual intercourse and 0 = otherwise).
b
A binary indicator (1 = used neither condom nor birth control when having sex and 0 = otherwise).
c
Weighted average of percentage of correct responses to 9 questions regarding pregnancy and STI prevention topics and percentage of correct responses to
9 questions regarding condom use.
d
Average rating of 10 items on 4-point scale (ranging from 1 = not important to 4 = very important) on the importance of healthy sexual behaviors.
e
Average rating of 5 items on a 4-point scale (ranging from 1 = very difficult to 4 = very easy) on difficulty of skills relate to managing relationship and
choices.
f
Response on 4-point scale (ranging from 1 = definite intention to 4 = no intention) to the question “Do you intend to have sexual intercourse in the next
12 months?”
g
Response on 4-point scale (ranging from 1 = no intention to 4 = definite intention) to the question “If you were to have sexual intercourse in the next
12 months, would you intend to use (or have your partner use) a condom?”

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analyses based on the alternative sample ex- processing and analyses, and oversaw the analysis team. 8. Kana9iaupuni S. A Brief Overview of Culture-Based
L. Toms Barker served as the overall project director of Education. Honolulu, HI: Kamehameha Schools Research
cluding the assignment blocks with the dropped the study and as the lead researcher for the implementation & Evaluation Division; 2007.
schools confirmed that findings were consistent study, developed the implementation analysis plan, led 9. Kana9iaupuni S, Ledward B, Jensen U. Culture-Based Ed-
and we controlled for observable characteristics the analyses, and provided the oversight of field data ucation and Its Relationship to Student Outcomes. Honolulu, HI:
collection activities. V. Chan contributed to the data Kamehameha Schools Research & Evaluation Division; 2007.
that differed at baseline, it is still possible that management and analyses; provided oversight for
potential bias resulting from overall and differ- processing baseline and follow-up data; assisted with 10. Kaiwi MK, Kahumoku W. Makawalu: Standards,
creating analysis indicators, the impact estimation, and Curriculum, and Assessment for Literature Through an In-
ential attrition across the conditions may remain. digenous Perspective. Vol. 3. Honolulu, HI: Kamehameha
writing up the results; and contributed to the discussion
To summarize, Pono Choices, a culturally section. J. Eucogco contributed to the data analyses Schools; 2006.
responsive intervention targeting early ado- and writing and to the background literature review and 11. Moore KA, Sugland BW. Next Steps and Best Bets:
lescents, did not lead to detectable behavioral the interpretation of the results and assisted with the Approaches to Preventing Adolescent Childbearing. New York,
impact estimation and drafting of the results. NY: Child Trends; 2001. Available at: http://eric.ed.
changes at 12 months after baseline. The gov/?id=ED414555. Accessed August 27, 2015.
program, however, did have a statistically ACKNOWLEDGMENTS 12. Hawkins JD, Catalano RF, Kosterman R, Abbott R,
significant impact on knowledge regarding This article is based on a study funded by a Teen Hill KG. Preventing adolescent health-risk behaviors
adolescent pregnancy and STI prevention. Pregnancy Prevention Research and Demonstration by strengthening protection during childhood. Arch
Program (Tier 2) grant (TP2AH000017) from the Office Pediatr Adolesc Med. 1999;153(3):226–234.
Because of the curriculum’s cultural focus, we on Adolescent Health (OAH), US Department of Health 13. Abe Y, Toms Barker L, Chan V, Eucogco J. The Final
conducted additional exploratory analyses for and Human Services (HHS). The study was conducted Impact Evaluation Report: Evaluation of the Pono Choices
the subsample of Native Hawaiian students: by IMPAQ International, LLC, an independent evaluator Program—A Culturally-Responsive Teen Pregnancy and
contractedbythegrantee,theUniversityofHawai9i at Manoa. Sexually Transmitted Infection Prevention Program for Middle
Additional subgroup analyses suggested that The full report from the study on which this article is based is School Youth in Hawai9i. IMPAQ International. Available
the effects for the Native Hawaiian subsample located on OAH’s Web site at: http://www.hhs.gov/ash/ at: http://www.hhs.gov/ash/oah/oah-initiatives/
tended to be larger, albeit not statistically oah/oah-initiatives/evaluation/grantee-led-evaluation/ evaluation/grantee-led-evaluation/grantees-2010-2014.
grantees-2010-2014.html. The study was registered with html. Accessed September 30, 2016.
significant except for the knowledge measure ClinicalTrials.gov (trial no. NCT02612324).
(Table E, available as a supplement to the online We thank the University of Hawai9i team—especially 14. Centers for Disease Control and Prevention. Youth
Kelly Roberts, Tammy Tom, and Holly Manaseri—for online. Available at: https://nccd.cdc.gov/youthonline/
version of this article). Further analysis also App/Default.aspx. Accessed August 27, 2015.
their support of the evaluation and their sharing of
found that the difference in knowledge results key implementation data. We are also grateful to 15. Kirby D, Lepore G. Sexual Risk and Protective Factors:
between Native Hawaiian and other students Futoshi Yumoto, a former IMPAQ staff member, for Factors Affecting Teen Sexual Behavior, Pregnancy, Childbearing,
was not statistically significant. One implication his contribution to psychometric analyses; Colleen and Sexually Transmitted Disease: Which Are Important? Which
McLelland for her contribution in leading field Can You Change? Washington, DC: National Campaign
worth exploring further is the potential for data collection and providing project assistance; to Prevent Teen and Unplanned Pregnancy; 2007.
culturally responsive interventions to bridge the and Ward Research staff for invaluable data collection 16. Kirby D. Emerging Answers 2007: Research Findings on
support. Furthermore, we thank the principals,
gap in student outcomes between the targeted Programs to Reduce Teen Pregnancy and Sexually Transmitted
teachers, and students who participated in the data Diseases. Washington, DC: National Campaign to Pre-
groups and the broader population. collection for their cooperation with vent Teen and Unplanned Pregnancy; 2007.
These early results indicate that further and contributions to this study.
17. Kirby D, Short L, Collin J, et al. School-based pro-
research could reveal whether and how grams to reduce sexual risk behaviors: a review of ef-
HUMAN PARTICIPANT PROTECTION
a culturally responsive curriculum might ef- The study was approved by the University of Hawai9i at
fectiveness. Public Health Rep. 1994;109(3):339–360.
fectively support a population known to be at Manoa institutional review board. Informed consent was 18. Terzian M, Andrews KM, Moore KA. Preventing
higher risk for adolescent pregnancy and STIs. obtained from students’ parents. Multiple Risky Behaviors: An Updated Framework for Policy
and Practice. Washington, DC: Child Trends; 2011.
Further research could also show whether
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CONTRIBUTORS 6. Castagno AE, Brayboy BMJ. Culturally responsive ated with characteristics of high-risk youth. Eval Program
Y. Abe and L. Toms Barker drafted, reviewed, and revised schooling for indigenous youth: a review of the literature. Plann. 1997;20(1):27–45.
the submitted article. Y. Abe served as the lead meth- Rev Educ Res. 2008;78(4):941–993.
odologist for the study, led the outcome evaluation, 7. Cornelius C. Iroquois Corn in a Culture-Based Curriculum.
developed the impact analysis plan, led outcome data Albany: State University of New York Press; 1998.

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