Athens Insomnia Scale-Validation of An Instrument Based On ICD-10 Criteria PDF

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Journal of Psychosomatic Research 48 (2000) 555 ± 560

Athens Insomnia Scale: validation of an instrument


based on ICD-10 criteria
Constantin R. Soldatos*, Dimitris G. Dikeos, Thomas J. Paparrigopoulos
Sleep Research Unit, Department of Psychiatry, Athens University Medical School, Athens, Greece
Received 21 June 1999

Abstract

Objectives: To describe and validate the Athens Insomnia sistency, for both versions of the scale, the Cronbach's a was
Scale (AIS). Methods: The AIS is a self-assessment psychometric around 0.90 and the mean item ± total correlation coefficient was
instrument designed for quantifying sleep difficulty based on the about 0.70. Moreover, in the factor analysis, the scale emerged as
ICD-10 criteria. It consists of eight items: the first five pertain to a sole component. The test ± retest reliability correlation coeffi-
sleep induction, awakenings during the night, final awakening, cient was found almost 0.90 at a 1-week interval. As far as
total sleep duration, and sleep quality; while the last three refer to external validity is concerned, the correlations of the AIS-8 and
well-being, functioning capacity, and sleepiness during the day. AIS-5 with the Sleep Problems Scale were 0.90 and 0.85,
Either the entire eight-item scale (AIS-8) or the brief five-item respectively. Conclusion: The high measures of consistency,
version (AIS-5), which contains only the first five items, can be reliability, and validity of the AIS make it an invaluable tool in
utilized. The validation of the AIS was based on its administration sleep research and clinical practice. D 2000 Elsevier Science Inc.
to 299 subjects: 105 primary insomniacs, 144 psychiatric patients All rights reserved.
and 50 non-patient controls. Results: Regarding internal con-

Keywords: Scale; Validation; Insomnia; Sleep disorders; ICD-10

Introduction Problems Scale [13], the Pittsburgh Sleep Quality Index


[14], and the Karolinska Sleep Diary [15,16].
Problems with poor sleep are quite frequent in the The evolution of diagnostic concepts regarding insomnia
general population; their prevalence ranges from 10% to is reflected in the various classification systems, which have
30% [1 ± 5] and it is much higher among patients with been in use over the last two decades [17 ± 21]. The
psychiatric disorders [5 ±8]. In most studies assessing sub- classification published in 1979 by the Association of Sleep
jective sleep difficulties, self-devised questionnaires and Disorders Centers required a sleep laboratory based criterion
sleep diaries are utilized. Such instruments may be adequate of reduced sleep quantity for the diagnosis of insomnia [17].
for the purposes of a given study allowing comparisons In drafting the DSM-III-R, the clinical approach prevailed,
between conditions or groups of individuals, but they are according to which the diagnosis of insomnia is based on
usually not standardized or uniform Ð making the integra- the patient's subjective perception of unsatisfactory sleep
tion of results from various studies impossible. Some quantity and/or quality [18]. Ever since, for the diagnosis of
standardized instruments, however, have been developed insomnia impaired sleep quality is given equal importance
for the measurement of sleep difficulties in clinical settings: as that of reduced sleep quantity and the patient's subjective
the Leeds Sleep Evaluation Questionnaire [9,10], the St. assessment is not discarded [19 ± 21].
Mary's Hospital Sleep Questionnaire [11,12], the Sleep Following the publication of the ICD-10 diagnostic
criteria for insomnia [20], the need arose to develop a scale
as a tool to assist clinicians in assessing the severity of
* Corresponding author. Eginition Hospital, 72-74 Vas. Sophias Ave., insomnia based on these globally accepted criteria. The
11528 Athens, Greece. Tel.: +30-301-7289324; fax: +30-301-7251312. rationale for the development of such a tool, the Athens
E-mail address: egslelabath@hol.gr (C.R. Soldatos). Insomnia Scale (AIS), has been presented previously [22].

0022-3999/00/$ ± see front matter D 2000 Elsevier Science Inc. All rights reserved.
PII: S 0 0 2 2 - 3 9 9 9 ( 0 0 ) 0 0 0 9 5 - 7
556 C.R. Soldatos et al. / Journal of Psychosomatic Research 48 (2000) 555±560

The purpose of the present paper is to provide a detailed its simple and straightforward format, which would be
description of the AIS and documentation of its validation. expected to pose no major problems for the translation.
Then, one of the authors (D.G.D.) translated the scale into
Greek. The Greek translation was examined by the bilingual
Methods group as well as by a three-member unilingual group, who
proposed only a few minor modifications of the Greek
Description of the scale wording. The modified Greek text was back-translated into
English by the third author (T.J.P.). Finally, the back-
The AIS is a self-administered psychometric instrument translation was carefully examined by the bilingual group,
consisting of eight items (Appendix A). The first five items who decided that the Greek translation of the AIS Ð as had
of the AIS (assessing difficulty with sleep induction, awa- been amended by the unilingual group Ðwas equivalent to
kenings during the night, early morning awakening, total the original English text.
sleep time, and overall quality of sleep) correspond to
criterion A for the diagnosis of insomnia according to Sample characteristics
ICD-10, while the requirements of a minimum frequency
(at least three times a week) and duration (1 month) of any Following the approval of the project by the institutional
complaint correspond to criterion B of the ICD-10 [20]. The review committee, the AIS was given to 105 primary health
ICD-10 requirements of marked distress caused by the sleep care patients presenting with a complaint of insomnia not
problem and/or interference with ordinary activities of daily attributed to any obvious underlying cause (primary insom-
living (criterion C) are covered through the strictly sub- nia), 100 psychiatric outpatients, 44 psychiatric inpatients,
jective nature of the response options for every item of the and 50 non-patient controls. Thus, the total sample consisted
scale as well as through the content of the last three items of 299 subjects. As Table 1 shows, 42% of the subjects were
pertaining to the next day consequences of insomnia (pro- males and 58% females with a similar sex ratio across the
blems with sense of well-being, functioning, and sleepiness four subgroups of subjects. The age distribution differed
during the day). somewhat among these subgroups; primary insomniacs were
Each item of the AIS can be rated 0 ± 3, (with 0 the oldest and psychiatric inpatients the youngest (Table 1).
corresponding to ``no problem at all'' and 3 ``very serious All subjects were informed on the research nature of the
problem''). The responders are requested to rate positive if project and all agreed to participate. Primary health care
they had experienced the sleep difficulty described in each patients were recruited through general practitioners and
item at least three times a week during the last month or other non-psychiatric physicians functioning in out-patient
some other period of time, whose length depends on the services of the Hellenic National Health System or in
purpose of a given study. private medical practice settings. Psychiatric patients were
Two versions of the scale can be used. Either the entire those attending the facilities of the Department of Psy-
eight-item scale (AIS-8) Ð with a total score ranging from 0 chiatry of the University of Athens. Finally, non-patient
(denoting absence of any sleep-related problem) to 24 controls were recruited from among the researchers'
(representing the most severe degree of insomnia) Ð or friends and acquaintances.
the brief five-item version (AIS-5), which is limited to the
first five items Ð with a total score ranging from 0 to 15. Assessment procedures
The AIS-8 is intended for use in a fully developed clinical
setting, while the AIS-5 is mainly used when there is a need The subjects were asked to record on the AIS their
to focus just on difficulty with sleep quantity and quality. estimate of any sleep difficulty they might have experienced
The last three items of the AIS-8 refer to daytime symptoms
that often emerge as a consequence of nocturnal sleep
Table 1
disturbance in insomniac patients. However, these symp-
Characteristics of the sample in terms of sex and age
toms may be also caused by sleep disorders other than
Age
insomnia, such as narcolepsy and obstructive sleep apnea.
The AIS was first developed in English by the senior Male Female Mean ‹ S.D. Range
author (C.R.S.), who was the expert responsible for drafting Primary insomniacs 43 62 58.9 ‹ 10.2 21 ± 79
the original diagnostic criteria for the sleep disorders section (n = 105) (41.0%) (59.0%)
Psychiatric outpatients 41 59 43.0 ‹ 13.3 19 ± 78
of ICD-10 [20]. For the purposes of the present study,
(n = 100) (41.0%) (59.0%)
however, the AIS had to be translated in Greek. Thus, in Psychiatric inpatients 20 24 32.3 ‹ 14.2 18 ± 70
order to secure equivalence of the Greek translation to the (n = 44) (45.5%) (54.5%)
original English text the guidelines of the World Health Non-patient controls 23 27 37.2 ‹ 10.5 22 ± 63
Organization were followed [23]. According to these guide- (n = 50) (46.0%) (54.0%)
Total sample (n = 299) 127 172 46.0 ‹ 15.7 18 ± 79
lines, a bilingual group of three experts examined and
(42.4%) (57.6%)
approved the conceptual structure of the English text, noting
C.R. Soldatos et al. / Journal of Psychosomatic Research 48 (2000) 555±560 557

Table 2 Table 4
Internal consistency of the AIS (Cronbach's a) Test ± retest reliability (Pearson's correlation coefficients)
AIS-8 AIS-5 AIS-8 total score 0.89
AIS-5 total score 0.88
All subjects (n = 299) 0.89 0.87
Primary insomniac patients (n = 105) 0.90 0.85
Single items
Psychiatric outpatients (n = 100) 0.86 0.81
Sleep induction 0.86
Psychiatric inpatients (n = 44) 0.85 0.86
Awakenings during the night 0.80
Controls (n = 50) 0.75 0.75
Final awakening 0.80
Total sleep duration 0.82
Sleep quality 0.70
during the period of the last month. To evaluate test ±retest Well-being during the day 0.85
reliability, all psychiatric patients and the controls (N = 194) Functioning capacity during the day 0.79
were assessed through the AIS at two time points a week Sleepiness during the day 0.77
apart from each other. The controls and psychiatric inpati-
p < 0.001 for each one of the above correlations.
ents (N = 94) were also administered the Sleep Problems
Scale [13] as an external validator.
remained practically unchanged when any one of the items
Data analysis was removed from the calculation (a if item deleted ranging
from 0.83 to 0.89). Also, the mean item ±total correlation
The internal consistency of the scale was measured based coefficients were high (0.67 for AIS-8 and 0.69 for AIS-5),
on Cronbach's a [24] for the whole scale, as well as for all- with individual item values ranging from 0.53 to 0.75 ( p <
but-one items if any one was deleted (``a if item deleted''). 0.001 for each one of the correlations). For both versions of
The correlation of each item score to the total scale score the AIS, the factor analysis demonstrated that the entire
(``item ± total correlation'') was also measured through Pear- scale emerged as a sole component (i.e., only one compo-
son's correlation coefficients. Additionally, the scale was nent had an eigenvalue greater than 1.0) with high percen-
subjected to factor analysis; in the extraction method of the tages of variance explained and all items contributing
principal component analysis, the eigenvalue threshold was practically equally to the component either in the case of
set at 1.0. Pearson's correlation coefficients were computed AIS-8 or in that of the AIS-5 (Table 3).
for the evaluation of test ± retest reliability and for the The correlations of either the AIS-8 or the AIS-5 score
external validation of the AIS against the Sleep Problems with the Sleep Problems Scale score were found to be very
Scale [13]; the respective correlations pertained to total scale strong, with Pearson's correlation coefficients of 0.90 and
scores as well as to single-item ratings. All assessments 0.85, respectively ( p < 0.001 in either case). Finally, the
were performed for both the AIS-8 and the AIS-5 and were test ± retest reliabilities for both the AIS-8 and AIS-5 total
executed through the use of the Statistical Package for scores, as well as for every individual item, were also found
Social Sciences (SPSS-8.0). to be very satisfactory (Table 4).

Results Discussion

The internal consistency measures of AIS-8 and AIS-5, The rationale for the development of the AIS, a scale for
based on Cronbach's a, are quite high for the total group the assessment of insomnia according to ICD-10 principles,
and each subgroup of subjects (Table 2). Cronbach's a is based on the necessity to give appropriate importance to
subjective sleep difficulty and to specify a time-frame as
Table 3 well as a minimum frequency for various sleep related
Factor analysis: eigenvalue, variance explained, and factor loadings problems [22]. In this paper, we present the validation of
AIS-8 AIS-5 the AIS, based on a large sample of subjects including many
users of health services with frequent sleep problems. The
Eigenvalue 4.56 3.29
Percentage of variance explained 56.9% 65.8% administration and assessment of AIS showed that this scale
is very reliable, practical, and easy to use. Its utilization
Factor loadings of the individual scale items provides a reliable measure of the intensity of insomnia.
Sleep induction 0.74 0.78 Moreover, the consistency, reliability, and validity of the
Awakenings during the night 0.71 0.78
scale were found to be very satisfactory.
Final awakening 0.81 0.85
Total sleep duration 0.79 0.85
Sleep quality 0.82 0.80 Consistency of the AIS
Well-being during the day 0.78
Functioning capacity during the day 0.75 The internal consistency of the AIS, either in the AIS-8
Sleepiness during the day 0.62
version or the AIS-5 version, was found to be very
558 C.R. Soldatos et al. / Journal of Psychosomatic Research 48 (2000) 555±560

satisfactory (Cronbach's a: 0.89 and 0.87, respectively). performance of the AIS in patient samples different than
This demonstrates the very high degree of homogeneity of those utilized in the present study.
the AIS, which is further supported by the finding that a
does not practically change if any one of the items is Reliability of the AIS
deleted and by the high correlation coefficients of the
item ±total correlations. As expected, the lowest internal The test ±retest reliability of the AIS was very satisfac-
consistency measures for both AIS-8 and AIS-5 were tory both for the whole scale in its two versions (0.89 for the
found for the subgroup of healthy controls. Even then, AIS-8 and 0.88 for the AIS-5) and for each individual item
however, the Cronbach's a values were quite high (0.75 (ranging from 0.70 to 0.86). The test ± retest correlation
for either the AIS-8 or the AIS-5). coefficient of the total score of the Pittsburgh Sleep Quality
The internal consistency of the AIS is very satisfactory Index (0.85) and the range of single-item coefficients of the
not only by itself, but also in comparison to other standar- St. Mary's Hospital Sleep Questionnaire (from 0.70 to 0.96)
dized scales for the measurement of sleep difficulty in were similarly high [12,14]. The total score test ± retest
clinical settings. Indeed, the Cronbach's a for the AIS is coefficients for the Sleep Problems Scale were much lower
higher than that for the Pittsburgh Sleep Quality Index (0.59 at the 3-month retest and 0.42 at the 6-month retest),
[14,25], the Sleep Problems Scale [13], and the Karolinska but the reexamination was performed at a much later time
Sleep Diary's sleep quality index component [26]. The compared to the other scales [13].
mean item ± total correlation coefficient of the AIS was
found to be 0.67 for the AIS-8, and 0.69 for the AIS-5, Validity of the AIS
while the mean component ± total correlation coefficient of
the Pittsburgh Sleep Quality Index was 0.58 [14]. The mean The external validity of the AIS was measured against
item ±total correlation of the Sleep Problems Scale (0.79) the total score of the Sleep Problems Scale [13]. The
was somewhat higher than that of the AIS, but the calcula- correlation with that scale was very high, with coefficients
tion for the Sleep Problems Scale was based on a homo- being 0.90 and 0.85 for the AIS-8 and AIS-5, respectively.
geneous sample of air-traffic controllers to whom a shorter The Sleep Problems Scale is similar to the AIS in that it is
form of the scale, which included only four items closely comparatively simple and contains about the same items,
related to sleep difficulty, was administered [13]. although for its rating, it is based on frequency of occur-
The factor analysis provided further evidence for the rence, rather than severity, of the sleep problems [13]. To
homogeneity of the AIS. From this analysis, the whole our knowledge, the AIS is the only scale that has been
scale emerged as only one component; the eigenvalue was correlated with another sleep scale. The Sleep Problems
4.6 for AIS-8 with nearly 60% of the variance explained Scale was correlated with psychopathology scales not spe-
and all item loadings being equally high. Similarly cifically pertaining to sleep [13]. Polysomnographic mea-
satisfactory were the eigenvalue, percentage of variance sures have been used for the external validation of the
explained, and the item loadings for the AIS-5. Three Karolinska Sleep Diary and the Pittsburgh Sleep Quality
other sleep scales have been subjected to factor analysis: Index; the correlations of the Karolinska Sleep Diary scores
the Karolinska Sleep Diary, the St. Mary's Hospital Sleep with the polysomnographic measures were satisfactory [26],
Questionnaire, and the Leeds Sleep Evaluation Question- while those of the Pittsburgh Sleep Quality Index were not
naire. The Karolinska Sleep Diary was found to consist of [14]. Another important measure of external validity of a
two well-defined components that explained the 68% of given scale is its sensitivity to the change of severity of the
the total variance with eigenvalues 2.9 and 1.8 [26]. The condition it assesses. For example, the effects of a hypnotic
St. Mary's Hospital Sleep Questionnaire was also found therapy should be detected through a significant change in
to consist of two components (eigenvalues 4.6 and 1.4), the scale score. Such an external validity measure is
which actually could not be clearly defined [27]. The obtained for AIS, based on a study in which a hypnotic
Leeds Sleep Evaluation Questionnaire was found to be drug of known potency is used (publication in preparation).
even less compact, having four separate components that
pertain to sleep latency, quality of sleep, awakening from Applicability of the AIS
sleep, and behavior following wakefulness [28]. Thus, the
AIS emerges as more compact than all previously pub- The AIS can be utilized in clinical practice to measure
lished scales. However, the high degree of homogeneity reliably the intensity of perceived sleep-related problems by
of the AIS shown in the present study may be due to the a given patient. More specifically, the first five items
fact that the patients presented either with primary in- provide a measure of difficulty with sleep quantity and
somnia or with psychogenic sleep difficulties. It is quite quality, while a measure of the daytime consequences of
possible that a lower degree of homogeneity of the AIS insomnia is provided by the last three items. Besides its use
could have been found among patients suffering from a in clinical practice, the AIS can be also utilized as a research
variety of other sleep disorders, such as narcolepsy, sleep tool. The usual time-frame of assessment according to ICD-
apnea, etc. In this context, it would be useful to test the 10, is 1 month. However, when the scale is used for specific
C.R. Soldatos et al. / Journal of Psychosomatic Research 48 (2000) 555±560 559

research purposes, this period can be modified according to Index, the AIS is much simpler and easier to use. The
the needs of the specific research project. Pittsburgh Sleep Quality Index has 18 questions to be
The AIS is devised to measure purely subjective esti- answered by the subject, plus an additional six by a room-
mates of sleep difficulty. Should the need arise for the AIS mate [14]. To score the Pittsburgh Sleep Quality Index,
to be rated by an interviewer (e.g., when dealing with many relatively complex calculations are needed, which
illiterate or sight-impaired subjects), the rater must always make it rather cumbersome for clinicians and could sub-
bear in mind that only the subjective feelings of the stantially increase the time and cost of any investigation in
interviewee are considered for the rating. Thus, the severity which it is utilized.
of the interviewee's sleep difficulty as estimated by the In conclusion, the AIS is a scale for use in a large variety
interviewer (based on his/her own evaluation of any addi- of clinical and research settings where the quantification of
tional information, e.g. number of hours of sleep or approx- sleep problems is required. The AIS compares favorably
imate duration of sleep onset latency, etc.) should not be against other scales regarding all measures of consistency,
taken into account since it may actually be at variance with reliability, and validity. These properties, of the AIS together
the interviewee's subjective assessment. with its simplicity, make it an invaluable psychometric
The Leeds Sleep Evaluation Questionnaire, the St. instrument in sleep research and clinical practice.
Mary's Hospital Sleep Questionnaire, and the Karolinska
Sleep Diary [9± 12,15,16] are relatively simple in their use,
but they are designed to evaluate mainly the sleep of the Acknowledgments
previous night and their purpose is not to assess sleep
difficulties over periods of time comparable to those re- The authors wish to express their appreciation to the
quired in most diagnostic classification systems in use [18 ± members of the bilingual group of experts (Drs. V. Mavreas,
21]. Similarly to the AIS, the Sleep Problems Scale and the G. Papadimitriou and P. Sakkas) and those of the unilingual
Pittsburgh Sleep Quality Index have wide applications, group (Drs. D. Pappa, A. Politis and C. Psarros) for their
including their use in a variety of clinical and research assistance in the establishment of the equivalence of the
settings [13,14]. Compared to the Pittsburgh Sleep Quality Greek translation of the AIS to its original English text.

Appendix A.
Athens Insomnia Scale
ID:__________ Age:_________ Sex:_________ Date:________

Instructions: This scale is intended to record your own assessment of any sleep difficulty you might have experienced. Please, check (by circling the
appropriate number) the items below to indicate your estimate of any difficulty, provided that it occurred at least three times per week during the
last montha

Sleep induction (time it takes you to fall asleep after turning-off the lights)
0: No problem 1: Slightly delayed 2: Markedly delayed 3: Very delayed or did not sleep at all

Awakenings during the night


0: No problem 1: Minor problem 2: Considerable problem 3: Serious problem or did not sleep at all

Final awakening earlier than desired


0: Not earlier 1: A little earlier 2: Markedly earlier 3: Much earlier or did not sleep at all

Total sleep duration


0: Sufficient 1: Slightly insufficient 2: Markedly insufficient 3: Very insufficient or did not sleep at all

Overall quality of sleep (no matter how long you slept)


0: Satisfactory 1: Slightly unsatisfactory 2: Markedly unsatisfactory 3: Very unsatisfactory or did not sleep at all

Sense of well-being during the day


0: Normal 1: Slightly decreased 2: Markedly decreased 3: Very decreased

Functioning (physical and mental) during the day


0: Normal 1: Slightly decreased 2: Markedly decreased 3: Very decreased

Sleepiness during the day


0: None 1: Mild 2: Considerable 3: Intense
a
The period of the self-assessment may vary, depending on the design of a given study. Whenever the self-assessment pertains to a period other than that of
the last month, the second sentence of the instructions should be rephrased accordingly.
560 C.R. Soldatos et al. / Journal of Psychosomatic Research 48 (2000) 555±560

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