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Cleft Lip and Palate Seminar Ed PDF
Cleft Lip and Palate Seminar Ed PDF
PALATE
Presenter : Dr CHARISMA THIMMAIAH
Guided by : DR MADHUSUDHAN
CONTENTS
• Introduction
• Definition
• Embryology and development of palate
• Pathogenesis of clefting
• Aetiology of cleft lip and palate
• Classification of cleft and palate
• Management of cleft lip and palate
•Multidisciplinary sequencing of treatment
•Role of pedodontist
•Pre surgical orthopedics
Nasoalveolar molding appliance
Pre maxillary retraction
•Prosthodontic approach
•Orthodontic approach
•Surgical approach
•Conclusion
•References
INTRODUCTION
• Clefts of the lip and palate are the most common congenital deformities
involving the orofacial region.
– Primary palate
– Secondary palate
• The critical period of development is from the end of 6 th week till the
beginning of the 9th week.
DEVELOPMENT OF PALATE
Primary palate
• a secondary nasal septum grows down from the roof of the stomodeum
behind the primary nasal septum, dividing the nasal part of the oronasal
cavity into two.
• During 7th week of development the oral part of the oronasal cavity
becomes completely filled by the developing tongue
• Growth of the palatal shelves continues and they come to lie vertically.
• During 8th week, stomodeum enlarges, tongue drops down and vertically
inclined palatal shelves become horizontal.
• Palatal shelves contact each other in the midline to form the definitive or
secondary palate
• Medial edge epithelia of the 2 shelves fuse to form the midline epithelial
seam.
Most clefts of the lip and palate generally are related to multifactorial inheritance .
1. Nutritional deficiency:-
• Van der woude syndrome (lip pits with cleft lip/ palate)
• EEC syndrome (ectrodactyl, ectodermal dysplasia and clefting)
• Larsen syndrome (originally thought to be reessive)
Autosomal recessive
• Chondrodysplasia punctata (conradi syndrome)
• Meckel syndrome
• Orofacial digital syndrome, type II
• Fryns syndrome
X linked
• Orofaciodigital syndrome, type I
• Isolated X linked cleft palate with ankylooglossia
Chromosomal
• Trisomy 13
• Trisomy 18
Non mendelian
• Pierre robin sequence
• Clefting with congenital heart disease.
CLASSIFICATION OF CLEFT LIP AND
PALATE
Submucous
cleft
VEAU CLASSIFICATION (1931)
CLEFT LIP
• Class I : U/L notching of vermillion border, not extending into the lip.
• Class II : cleft extending into the lip, but not including the floor of the nose.
• Class IV: any b/l cleft of the lip, whether incomplete or complete.
• CLEFT PALATE
• Group 1:- Defects of the soft palate only.
I. Cleft of prepalate:
• “Y” logo are each divided into three sections, representing the lip, the
alveolus and the hard palate as far back as the incisive foramen.
• The stem of the “Y” is also divided into three parts, representing varying
degrees of clefting of the hard and soft palates
MILLARDS MODIFICATION OF STRIPED Y
• The inverted triangles represent the nasal arch the upright triangles
represent the nasal floor.
PROBLEMS ASSOCIATED WITH
CLEFT LIP & PALATE
DENTAL
Crossbites
Taurodontism, dilacerations
SKELETAL
Maxillary deficiency
Mandibular prognathism
Concave profile
HEARING AND SPEECH PATHOLOGY
• Otitis media
• Speech problems
Mc donald and Avery’s Dentistry for the child and adolescent: 9th edition
STAGE III: LATE PRIMARY/MIXED DENTITION STAGE(6 to 11 years)
• Ectopic eruption permanent central and lateral incisor
• Cross bite correction
• Maxillary expansion
Mc donald and Avery’s Dentistry for the child and adolescent: 9th edition
ROLE OF PEDIATRIC DENTISTS
• To create a proper plan of care for oral health and overall nutrition .
• Neonates with a cleft palate have difficulty in eating, which may lead to
failure to thrive.
The most important people associated at this stage are the parents.
a long-standing relationship between the cleft team and the affected family
must be established.
FEEDING MANAGEMENT
• Feeding problems often associated with cleft anomalies, make it difficult for
the infant to maintain adequate nutrition.
Hiremath V, Ashwini B, Rayannavar SL, Kumari N (2016) J Dent Health Oral Disord Ther 2016,
INFANT ORTHOPEDICS
• Brophy (1927) -passing of a silver wire through both the ends of the cleft
alveolus, and then progressively tightened the wire to approximate the ends of
the alveolus before lip repair.
• Hotz (1987) – premaxilla is normally placed, by age 10, face grows downward
and forward into balance with premaxilla
Grayson BH, Shetye PR. Presurgical nasoalveolar moulding treatment in cleft lip and palate
patients. Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of
HISTORY
• Grayson (1993) – first technique to correct the alveolus, lip and nose in
cleft infants
• Grayson (1999) adapted the addition of nasal stent to extend from the
anterior flange of an intraoral molding plate. This new technique was
named Nasoalveolar molding”
Grayson BH, Shetye PR. Presurgical nasoalveolar moulding treatment in cleft lip and palate
patients. Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of
1999:Grayson in his article listed four benefits of PNAM:
Grayson BH, Shetye PR. Presurgical nasoalveolar moulding treatment in cleft lip and palate
patients. Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of
NASOALVEOLAR MOULDING
Grayson BH, Shetye PR. Presurgical nasoalveolar moulding treatment in cleft lip and palate
patients. Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of
Objectives:
NASOALVEOLAR MOULDING
• Reduce severity of initial cleft deformity
• Reduction in the width of the alveolar cleft segments until passive contact of
the gingival tissues is achieved.
Protocol used in pre surgical NAM therapy
PROCEDURE
IMPRESSION MATERIALS
Nasoalveolar Molding for Infants Born with Clefts of the Lip, Alveolus, and Palate Barry
H. Grayson, D.D.S.1,2 and Deirdre Maull, D.M.D.2005
IMPRESSION TECHNIQUE
• Dubey (2011) made impression of the cleft region upper arch using ice cream
stick and impression compound.
•A number of positions have been adopted for cleft palate impression making in
infants including face down, upright Prone and even upside down
FABRICATION OF NAM APPLIANCE
• The retention arm’s vertical position should be at the intersection of the upper
and lower lip
• while retention button with the aid of elastics and extra-oral tapes secures the
molding plate in the oral cavity.
• The elastic on the surgical tape is looped on the retention arm of the
molding plate and the tape is secured to the cheeks.
• Elastics used are 0.25 inch and it should be stretched about two times the
diameter for activation force of about 2 Oz
Nasoalveolar Molding for Infants Born with Clefts of the Lip, Alveolus, and Palate Barry
ADJUSTMENT OF THE APPLIANCE
• Adjustments are made by selectively removing the hard acrylic and adding
the soft denture base material to the molding plate.
• The alveolar segments should be directed to its final and optimal position.
•Care must be taken to prevent the soft denture material from building up on
the height of the alveolar crest as this will prevent complete seating of the
moulding plate.
• The nasal stent is added to the intraoral molding plate when the cleft
alveolar gap is reduced to 5mm or less
• Stent – 0.036-in gauge round stainless steel wire and takes the shape of a
swan neck
• The intranasal portion is formed from hard acrylic, covered with a thin layer
of soft spongy acrylic denture liner
FIGUEROA’S TECHNIQUE,
• Rubber bands are connected to the acrylic plate for gentle retraction of the
premaxilla backward.
• A soft resin ball attaching to the acrylic plate across the prolabium is
sometimes used to maintain the nasolabial angle
• The top portion contains a soft resin molding bulb that fits underneath the
nasal cartilages for nasal molding.
• In this method also, nasal and alveolar molding was done simultaneously.
• In bilateral cases, there is a need for two retention arms as well as two nasal
stents which are similar in shape to the unilateral stent.
• After adding the nasal stents in the bilateral cleft, the attention is focused
on non-surgical lengthening of the columella.
• a horizontal band of the denture material is added to join the left &
right lower lobes of the nasal Stent, spanning the base of the columella
• This band sits at the nasolabial junction and defines this angle as the nasal tip
continues to be lifted and projected forward.
• The tape is adhered to the prolabium underneath the horizontal lip tape and
stretches downward to engage the retention arm with elastics.
• This vertical pull provides a counter stretch to the upward force applied to the
nasal tip of the nasal stent.
• Long-term:
• change in nasal shape is stable
• Shetty V et al (2017) - improves arch symmetry and stability, and thus may
prevent arch collapse in the long term
Complications and disadvantages:
• The premaxilla was retracted and the cleft gap was reduced with the use of
this active alveolar molding appliance within 3 months.
• This enabled better esthetic results after surgery by reducing tissue tension
and scar formation.
PREMAXILLARY RETRACTION
•In cases of bilateral cleft lip and palate, premaxillary segment may be
positioned severely anterior to the maxillary arch.
• Soft elastic tape (Microfoam Tape) can also be used for retraction.
• Bonnet and strap appliance is worn 24 hrs a day and is removed only for
feeding. Desired repositioning is accomplished within 6-8 weeks.
In case of laterally deviated premaxilla in an infant with a bilateral cleft lip
and palate, a straight extraoral force would not place premaxilla in facial
midline.
[Grayson et al 2001]
PROSTHODONTIC APPROACH
• The maxillary obturator is an intra oral prosthetic device that fills the
palatal cleft and thus provides a false roofing against which the child can
suckle.
• It also provides maxillary cross arch stability preventing the arch from
collapsing.
REQUISITES OF A CLEFT PALATE PROSTHESIS
Simple, easy
Regulate
Restore basic Worn by the to construct
efficiently the
function of patient with special
function of
respiration without attention to
speech,
phonation and discomfort retention,
breathing and
deglutition and damage occlusion and
swallowing
cosmetics
DESIGNS OF FEEDING OBTURATORS
Different Designs of Feeding Aids for Cleft Palatal Defects. J Health Edu Res Dev 4: 180. J
Health Edu Res Dev 4 Chugh A, Dahiya D, Thukral H, Verma S, Ahlawat A, et al. 2016
Technique Of Fabrication Of Obturators
Chacko, et al.: Simplified feeding appliance for a cleft palate infant Oct-Dec 2014 | Vol 32|
Technique Of Fabrication Of Obturators
Chacko, et al.: Simplified feeding appliance for a cleft palate infant Oct-Dec 2014 | Vol 32| Issue
An Alternative Impression Technique for an
Infant with Cleft Palate-Case report 2015
•A 3-day-old male infant with cleft palate
•Intra-oral examination revealed a cleft involving the uvula and soft palate exclusively
Modified tea-spoon
impression tray
Preliminary impression of Feeding plate
the infant
Canan Akay1, Duygu Karakis, Suat Yalug, Int Dent Res 2015;5(2):38-41)
Possible complications
Difficulty in removal of impression due to engagement of undercuts.
MANGEMENT
Back Blows
Chest Thrusts
Finger Sweeps
V.P Sabrinath et al. Caring for cleft lip and palate infants: impression procedures and appliances
Different designs of feeding obturators
1. Passive plate
Fig 1 fig 2
Fig 1 and fig 2 - obturator of autopolymerising resin attaching two orthodontic wire
and elastics or head bands
used when it is not feasible to close fistula in palate surgically, and removable
appliance is also not possible.
Different Designs of Feeding Aids for Cleft Palatal Defects. J Health Edu Res Dev 4: 180. J
Health Edu Res Dev 4 Chugh A, Dahiya D, Thukral H, Verma S, Ahlawat A, et al. 2016
a) Active appliances
Different Designs of Feeding Aids for Cleft Palatal Defects. J Health Edu Res Dev 4: 180. J
Health Edu Res Dev 4 Chugh A, Dahiya D, Thukral H, Verma S, Ahlawat A, et al. 2016
Velopharyngeal function & Speech
Considerations
• Adequate velopharyngeal closure prevents the passage of air from the
oropharynx into the nasopharynx during function.
• As a consequence, air and sound energy are transmitted into and through
the nasal cavity during speech.
• A prosthesis with a pharyngeal extension constructed for such patients so
that adequate valving for speech purposes can be developed
• They need to be remade periodically to account for growth and eruption of the
permanent dentition.
E.M Bispo et al (2011). Speech therapy for compensatory articulations and velopharyngeal
function: A case report. Journal of applied oral science : revista FOB. 19. 679-84. 1
ROLE OF ORTHODONTIST
• Orthodontists play a significant role in the treatment of a child with cleft lip
and palate there are four distinct processes.
• The first process begins from 0 to 7 years, after the initial treatment
plan is devised with the craniofacial team.
• The orthodontist will confer with the pediatric dentist and oral maxillofacial
surgeon that care for a child with cleft lip and palate .
Cleft lip and palate. Diagnosis & management. Samuel Berkowitz, 2 nd edition.
PRIMARY DENTITION TREATMENT
Palatal expanders
W-Arch expander Arnold Expander
MIXED DENTITION TREATMENT
•Minor crossbite correction by expansion of the maxilla with full time
retention.
•Alveolar bone grafting is done just before eruption of canine, thus space is
created for them to erupt.
Cleft lip and palate. Diagnosis & management. Samuel Berkowitz, 2 nd edition.
PERMANENT DENTITION TREATMENT
Cleft lip and palate. Diagnosis & management. Samuel Berkowitz, 2 nd edition.
SURGICAL APPROACH
LIP REPAIR
• The reconstruction of the lip should restore the faulty formation and the
defective development.
Blair, Brown, and McDowell introduced the design of a flap just above
the vermilion and a system of measurements to achieve reasonable
symmetry.
Cleft lip and palate. Diagnosis & management. Samuel Berkowitz, 2 nd edition.
MILLARD’S ROTATION ADVANCEMENT
OPERATION
• The incision is located at the philtrum column just below the columella,
often with a “cutback” incision on the non cleft side.
• The whole central flap is then rotated down to a normal position and the
defect just below the nostril floor is closed with a triangular flap from the
lateral cleft margin.
This was first described by Dr. Ralph Millard Jr. and was presented at the First
International Congress on Plastic Surgery in Stockholm in 1955.
TENNISON RANDALL REPAIR
• A triangular flap is created in the lateral side of the cleft to fit into the
triangular defect produced on the medial side of the cleft.
In this method vermillion flap from either lateral side is brought down over the
prolabium to augment the vermilion in the centre of upper lip.
PALATE REPAIR
• Early closure – Better speech and swallowing patterns develop early which
cant be corrected later.
PRINCIPLES OF PALATOPLASTY
• Minimal or no raw area should be left on the nasal side or the oral surface.
• Tension-free suturing.
• Two-layer closure in the hard palate region and a three-layer closure of the
soft palate.
• Veau-wardill-kilner Palatoplasty
A history of the repair of cleft lip and palate in Britain before World War II.Wallace AF
Ann Plast Surg. 1987 Sep; 19(3):266-75.
COMPLICATIONS OF CLEFT PALATE
SURGERY
IMMEDIATE COMPLICATIONS
• Haemorrhage
• Respiratory obstruction
• Hanging Palate
• Dehiscence of the repair
• Oronasal fistula formation
LATE COMPLICATIONS
• Bifid uvula
• Velopharyngeal Incompetence
• Abnormal speech
• Maxillary hypoplasia
• Dental malpositioning and malalignment
• Otitis media
CONCLUSION
97
REFERENCES
• Samuel Berkowitz. Celft Lip and Palate. 2006. 2nd edition Page number 451-8.
• Mc donald and Avery’s Dentistry for the child and adolescent: 9th edition
• Neelima Malik
• Graber Vanarsdall and Vig. Orthodontics: Current Principles and Techniques.
Elsevier 2012
• Inderbir Singh. Human embryology. Macmillan India. Seventh edition 2001.
• Sommerland BC. Management of cleft lip and palate. Current Paediatrics 1994
• Reddy S et al. Incidence of cleft Lip and palate in the
state of Andhra Pradesh, South India. Indian J Plast Surg. 2010
Jul-Dec; 43(2): 184–9.
• Allori AC et al. Cleft lip and palate classification: Thenand
Now.Cleft Palate–Craniofacial Journal 2016;53(1)
• John B. Thornton, Sue Nim Paul S. Howard. The incidence, classification,
etiology and embryology of oral clefts. Semin Orthod 1996;2:162-168
• Peter Mosby et al. Cleft Lip and Palate. Lancet 2009; 374: 1773–85
REFERENCES
• Jamal GA et al. Prevalence of Dental Anomalies in a Population of Cleft Lip and Palate
Patients. Cleft Palate–Craniofacial Journal, 2010;47(4):413-20
• Ana Paula Ramos Bernardes da Silva, Beatriz Costa, Cleide Felício de Carvalho Carrara,
Dental Anomalies of Number in The Permanent Dentition of Patients With Bilateral Cleft
Lip: Radiographic Study, The Cleft Palate-Craniofacial Journal. 2008;45(5):473-476.
• Berkowitz S. A Comparison of Treatment Results in Complete Bilateral Cleft Lip and
Palate Using a Conservative Approach Versus Millard-Latham PSOT Procedure. Semin
Orthod 1996;2:169-184
• Peterson S. The Relationship Between Timing of Cleft Palate Surgery and Speech
Outcome: What Have We Learned, and Where Do We Stand in the 1990s? Semin Orthod
1996;2:185-191
• Vlachos C. Orthodontic Treatment for the Cleft Palate Patient. Semin Orthod 1996;2:197-
204
• Posnick J. Orthognathic Surgery for the Cleft Lip and Palate Patient.Semin
Orthod 1996;2:205-14
• Gardener LK, Parr GR. Prosthetic Rehabilitation of the Cleft Palate Patient. Semin Orthod
1996;2:215-19
• Dalston R.Velopharyngeal Impairment in the orthodontic patients.Semin Orthod
1996;2:220-7.
Thank you