BARBOZA, SHERILYN B.

BSN2-NBA

DRUG STUDY

NAME OF THE MODE OF INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING

DRUG ACTION EFFECTS CONSIDERATION
GENERIC NAME: - May exert - To treat - Breast- CNS: Aphasia, ● Follow
- Methotrexat immunosupp severe feeding , cerebral facility
e ressive psoriasi hypersensitivit thrombosis, policy for
effects by s y to chills, preparing
BRAND NAME: inhibiting unrespon methotrexate or dizziness, and handling
- Rheumatrex replicatio sive to its components, drowsiness, drug;
n and other pregnancy fatigue parenteral
CLASS AND function therapy form poses a
CATEGORY: of T and CV: Chest pain, risk of
Chemical Class: possibly B deep vein carcinogenic
Folic acid lymphocyte thrombosis, ity,
analogue s. hypotension, mutagenicity
pericardial and
Therapeutic effusion teratogenici
Class: ty. Avoid
Antipsoriatic, ENDO: skin contact
Antirheumatic Gynecomastia ● Monitor
results of
EENT: Blurred CBC, chest
vision, X-ray, liver
Conjunctivitis, and renal
gingivitis, function
glossitis, tests, and
pharyngitis urinalysis
 before and
GI: Abdominal during
pain, anorexia, treatment
cirrhosis, ● Unless
diarrhea, contraindica
elevated liver ted,
function test increase
results patient’s
fluid intake
GU: Cystitis, to 2 to 3 L
hematuria, daily to
infertility, reduce the
menstrual risk of
dysfunction, adverse GU
nephropathy reactions
● Assess
HEME: Anemia, patient for
aplastic anemia, bleeding and
leukopenia, infection
neutropenia, ● Be aware
pancytopenia, that high
thrombocytopenia doses of
methotrexate
MS: Arthralgia, can impair
dysarthria, renal
myalgia, stress elimination
fracture by forming
crystals
RESP: Dry that
nonproductive obstruct
cough, dyspnea, urine flow.
interstitial To prevent
pneumonitis, drug
pneumonia,pulmon precipitatio
ary fibrosis or n,
 failure alkalinize
patient’s
SKIN: Acne, urine with
alopecia, sodium
altered skin bicarbonate
pigmentation, tablets, as
ecchymosis, ordered
erythema
multiforme

NAME OF THE MODE OF INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING

DRUG ACTION EFFECTS CONSIDERATION
GENERIC NAME: - Binds to - To treat - Fungal CNS: Ataxia, ● Use
- Methylpred intracellu ulcerati infection, behavioral cautiously
nisolone lar ve hypersensitivit changes, in patients
glucocorti colitis y to depression, with
BRAND NAME: coid - To treat methylprednisol dizziness, congestive
- Medrol receptors adrenal one or its euphoria, heart
and hyperpla components, fatigue, failure or
CLASS AND suppresses sia idiopathic headache renal
CATEGORY: inflammato - To treat thrombocytopeni insufficienc
Chemical Class: ry and a wide c purpura CV: Arrhythmias y because
Synthetic immune range of (from sodium
glucocorticoid responses immune hypokalemia), retention
by and cardiac arrest, and edema
Therapeutic inhibiting inflamma edema, fat can occur in
Class: accumulati tory embolism, heart patients
Anti- on of disorder failure, taking a
inflammatory, neutrophil , hypertension, corticostero
immunosuppressan s and includin hypertrophic ids
t monocytes g cardiomyopathy ● Give
at allergic (premature methylpredni
inflammati rhinitis infants),hypoten solone
on , sion tablets with
sites,stab asthma, food to
ilizing Crohn’s EENT: minimize
lysosomal disease, exophthalmos, indigestion
membranes, and glaucoma, and GI
suppressin systemic increased irritation
g the lupus intraocular ● Discard
antigen erythema pressure, parenteral
response tosus nystagmus, products
of posterior that are
macrophage subcapsular discolored
s and cataracts or contain
helper T particles
cells, and ENDO: Adrenal ● Inject I.M.
inhibiting insufficiency, form deep
the cushingoid into gluteal
synthesis symptoms (moon muscle.
of face, buffalo Avoid
inflammato hump, central injecting
ry obesity, into deltoid
response supraclavicular muscle
mediators, fat pad because of
such as enlargement), risk of
cytokines, diabetes subcutaneous
interleuki mellitus, growth atrophy
nes, and suppression in ● Arrange for
prostaglan children low-sodium
dins diet with
GI: Abdominal added
distention, potassium,
elevated liver as
enzymes, prescribed
hepatomegaly, ● Protect
hiccups, patient from
increased falling,
appetite, especially
melena, nausea, elderly
pancreatitis,pep patient at
tic ulcer risk for
GU: Amenorrhea, fractures
glycosuria, from
menstrual osteoporosis
irregularities,
perineal burning
or tingling

HEME: Easy
bruising,
leukocytosis

MS: Arthralgia,
aseptic necrosis
of femoral and
humeral heads,
Charcot-like
arthropathy,
compression
fractures,muscle
arthropathy,
twitching or
weakness

RESP: Pulmonary
edema

SKIN: Acne,
Allergic
dermatitis,
altered skin
pigmentation,
angioedema,
hypernatremia
 NAME OF THE MODE OF INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING
DRUG ACTION EFFECTS CONSIDERATION
GENERIC NAME: - Binds to - To treat - Hypersensitivit CNS: Euphoria, ● Administer
- Prednisone intracellu adrenal y to prednisone headache, once-daily
lar insuffic or its insomnia, doses of
BRAND NAME: glucocorti iency components, nervousness, prednisone
- Apo - coid and systemic fungal psychosis, in the
Prednisone receptors acute infection restlessness, morning to
and and seizures, match body’s
CLASS AND suppresses chronic vertigo normal
CATEGORY: inflammato inflamma cortisol
Chemical Class: ry and tory and CV: Edema, secretion
Glucocorticoid immune immunosu heart failure, schedule
responses ppressiv hypertension ● Because
Therapeutic by: e prednisone
Class: >Inhibiting disorder EENT: can produce
Anti- neutrophil and s Cataracts, many adverse
inflammatory, monocyte - To treat exophthalmos, reactions,
immunosuppressan accumulation at adrenoge glaucoma, assess
t inflammation nital increased regularly
site and syndrome ocular pressure for signs
suppressing - To treat and symptoms
their acute ENDO: Adrenal of such
phagocytic and exacerba insufficiency, reactions as
bactericidal tions of Cushing’s heart
activity multiple syndrome, failure and
sclerosi growth hypertension
> stabilizing s suppression in ● Monitor
lysosomal children, growth
membranes hyperglycemia pattern in
> suppressing children
antigen GI: Anorexia, ● Be aware
response of GI bleeding and that
macrophages and ulceration, prolonged
helper T cells increased use of
appetite, prednisone
> inhibiting indigestion may cause
synthesis of hypothalamic
inflammatory GU: Menstrual -pituitary-
response irregularities adrenal
mediators, such suppression
as cytokines, MS: Avascular
interleukins necrosis of
and joints, bone
prostaglandins fractures,
muscle atrophy
or weakness,
myalgia,

SKIN: Acne,
diaphoresis,
ecchymosis,
flushing,
petechiae,
striae, thin,
fragile skin