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The main way of spreading the SARS-CoV 2, also known as COVID-19 or Corona Virus is through
the droplet infection; when people cough, then the person will touch their face, eyes, or mouth. The
virus will travel inside the body with its path leading to intestines, spleen, or the lungs where billions of
epithelial cells are located. The Spike Protein (S protein) of the SARS-CoV 2 is a large type I
transmembrane protein ranging from 1,160 amino acids for avian infectious bronchitis virus and up to
1,400 amino acids for feline coronavirus which will bind with the recombinant ACE2 protein and inject
its genetic material. The membrane protein and the envelope protein are involved in the virus assembly.
The Nucleocapsid protein is a basic RNA-binding protein where the genetic material of the virus is
located. The genetic material is then injected to a cell which will begin its replication process. The cell
will be overloaded with copies of this virus until it reaches a critical point where it will self-destruct,
releasing the newly created virus and infect other cell on the body. When the immune cells kick in to
fight the virus, some of these immune cells gets infected and creates confusion, sends way more
immune cells to fight off infected cells, and attack its own cells, wasting resources and destroying
healthy cells.

Kurzgesagt - In a Nutshell. (2020, March 20). the coronavirus explained & what you should do [Video].
YouTube. https://www.youtube.com/watch?v=BtN-goy9VOY

Spike Protein / S Protein. (n.d.). Sinobiological (Protein|Antibody|ELISA Kit|cDNA Clone).


https://www.sinobiological.com/research/virus/hcov-spike-protein-overview

Structure, Function, and Evolution of Coronavirus Spike Proteins. (29, September). PubMed Central
(PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457962/

Nucleocapsid Protein. (n.d.). ScienceDirect.com | Science, health and medical journals, full text articles
and books. https://www.sciencedirect.com/topics/medicine-and-dentistry/nucleocapsid-protein

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