B2 QUESTIONS AND ANSWERS

1. Define the following common physical forms:

 Dusts
 Mist
 Fume

2. Identify the four main types of particle shape.

3. Explain what is meant by the term `effective spherical diameter’.

4. (i) What does ‘CHIP’ stand for

(ii) Outline the requirements under these regulations?

5. Explain what is meant by the following terms:

(i) Risk phrase

(ii) Safety phrase

6. Outline the purpose of a safety data sheet.

7. Outline the circumstances under which you do not need to provide a safety data
sheet (SDS) .

8. List the information that needs to be provided on a safety data sheet.

9. Explain what is meant by the acronym `GHS’.

10. Outline the purpose of `The Purple Book’.

11. With reference to substances dangerous for supply, outline the requirements for
the labelling of receptacles and other packaging.

12. Draw the British Medical Research Council (BMRC) penetration curve for
respirable particles.

13. Explain the BMRC penetration curve for respirable particles.

14. With reference to the measurement of concentrations of airborne dust, explain

what is meant by `the breathing zone’ of a worker.

15. With reference to the body’s defence mechanisms, give two examples that will
serve to illustrate the types of defence cell which are important in occupational health
and hygiene.

16. Define `phagocyte’.

17. With reference to inhalation and respiratory defences, explain what happens to the
following sized particles:
(i) larger than 10 µm
(ii) between 7 and 10 µm
(iii) 0.5 and 7 µm

18. Explain what happens to substances which pass through the alveolar membrane.

19. Explain what is meant by the term `inflammatory response’.

20. In addition to the classical disposal of antigens, outline the two other types of
immune response:
(i) Surveillance
(ii) Self-disposal

21. With reference to tumours, explain the following two types:

(i) Benign
(ii) Malignant

22. Describe the four main types of dermatitis.

23. Define ‘carcinogen’

24. Identify the three broad categories of harm under which dangerous health effects
could be categorised.

25. With reference to toxicology, explain what is meant by the `dose-response

relationship’.

26. In the dose/response relationship, outline what is meant by:

(i) Dose
(ii) Response

27. Explain how a dose-response relationship can be defined.

28. With reference to the dose/response curve, explain the significance of LD50.

29. Define the following:

 LD90
 TD50
 ED50

30. What is the NOAEL and why is it important for setting exposure limits.

31. Outline the three main types of toxicity tests.

(i)Acute toxicity tests
(ii)Subacute toxicity tests
(iii)Chronic toxicity tests

.
32. Define epidemiology.

33. Outline the following types of epidemiological studies:

 Cross-sectional studies
 Longitudinal studies

34. Identify the different types of data sources used in epidemiological studies.