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COVID-19 Management Protocol

AIIMS , New Delhi


th
20 March 2020

COVID-19 Suspect Any patient with acute respiratory illness (fever with at least one of
the following- cough or shortness of breath) with:
 History of travel to high-risk COVID-19 affected countries in the
last 14 days, or
 Close contact with a laboratory confirmed case of COVID-19 in
the 14 days, or
 Health care personnel (HCP) managing respiratory distress/
severe acute respiratory illness cases
Asymptomatic
traveller/close contact On developing symptoms
 Home quarantine
 Contact & droplet
precautions
Any one of:
1. Respiratory rate > 30 /min
2. SpO2 < 92% in room air
Mild case Moderate to severe case
3. Confusion/drowsiness
Low-grade fever, cough, 4. Systolic BP < 90 mmHg or
Admit & test
malaise, rhinorrhea, sore diastolic BP < 60 mmHg
throat without
shortness of breath

Treatment Test positive


Tab oseltamivir 75mg BD (for Test negative
 Oxygen supplementation to maintain
high risk influenza suspects)
Manage according to SpO2>94%
Antibiotics if needed
existing protocol  Antipyretics, antitussives, antibiotics as
(azithromycin+ amoxicillin
indicated
/clavulanate)
Tab Paracetamol 500 mg SOS  MDI preferred over nebulization
 Hydroxychloroquine (400 mg BD x 1 day f/b
200 mg BD x 5 days) may be considered
Call helpline
 Lopinavir/ritonavir(200 mg 2 tab BD) may be
011- 23978046 considered on case-to-case basis (with in 10
days of symptom-onset)
Test negative Test positive  Do not combine Hydroxychloroquine+
Lopinavir in view of drug interactions
Symptomatic  Home isolation (>72 hrs afebrile  Corticosteroids to be avoided
management or 7 days after symptom onset
whichever is longer)/two
negative samples 24 hours apart  Respiratory failure
 Hypotension After clinical &
 Paracetamol & symptomatic
 Worsening mental status radiological improvement
 Contact & droplet precautions  MODS
 Danger signs explained
Discharge
 High-risk individuals* may be
if two negative
considered for admission based
on clinical judgement Shift to ICU samples at least
24 hours apart

*High-risk for severe disease


 Age > 60 years
 NIV/HFNC to be used carefully in view of
 Cardiovascular disease including hypertension
risk of aerosol generation Improving
 DM, immunocompromised states
 Ventilator management as per ARDS
 Chronic lung/kidney/liver disease
protocol
 Conservative fluid management (if no
ICMR inclusion criteria for Lopinavir ritonavir
shock)
 High risk groups
 Standard care for ventilated patient
 Resp. rate >22/mt, SpO2<94%
 Closed suction and HME filters
 Lung infiltrates on Xray/CT
 Prone ventilation, ECMO for refractory
 New onset organ dysfunction
hypoxemia.

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