BUNGA ASRI IBRAHIM

442416038

KIMIA B

1. Metode ionisasi kimia (chemical ionization, CI)

 Spectrum
Sumber : (Pellegrini et al., 2002)

 Fragmentasi
 m/z: 150.13 (100.0%)
CH3
CH3
-
NH
HN
H
H

CH3 CH3

m/z: 119.09 (100.0%)

CH3 m/z: 91,05

NH
H

CH3

m/z: 59,07

sumber (M. Pellegrini, 2001)

2. Metode ionisasi kimia langsung (direct chemical ionization,DCI)

 Spektrum, sumber : (Argia, Yu and Miyatake, 1984)

 Fregmentasi
 H3CO H3CO
CH2 CH2
OCH3
O O
OCH3
O O CH2CH C C CH(CH2)12CH3
H H
OCH3
NCH3

C O
OCH3 OCH3
C23H47
H3C
O

OCH3
O HC
OCH3
HC OCH3
H3C C N O COOCH3

H2C CH2CH C C CH(CH2)12CH3

CH3 H H
OCH3
NCH3

C O

C23H47
H3CO H3CO m/z : 660,67
CH2 CH2

O O
OCH3
O O

OCH3

OCH3 OCH3

OCH3

COCH3
O H

HCOCH3 COOCH3
H3C C N O

H2COCH3
CH3

m/z: 1066,69

sumber (Toshio Argia, 1984)

3. Metode ionisasi semprotan elektron (electronspray ionization, ESI)

 Spektrum, sumber : (Steckel and Schlosser, 2019)
 Fregmentasi

N N
OH
NH
NH2

S
N
m/z: 144.05 (100.0%)
OH
S

m/z: 265.11 (100.0%)

N N

NH2

CH2

m/z: 122.07 (100.0%)

sumber (Arnold Steckel, 2019)

4. Metode pengeboman atom cepat (fast atom bombardment, FAB)
 Spektrum, sumber : (Sinha and Dua, 2004)
  Fregmentasi
CH3 H H
H2 H2 H2
N C C C C NH2 N
H

N CH3
H2 H2
N C C C C NH2 O
H H2 H2 H2
O NH C C C C NH2
CH3
H H2 H2 H2
CH3 NH C C C C NH2 CH3

CH3
m/z: 262.19 (100.0%)

m/z: 358.26 (100.0%) H

H H N

O CH3 H2N C CH2

H
H H2 m/z: 201.10 (100.0%)
CH3 HN C C C CH2
H

CH3

m/z: 243.15 (100.0%)

H
H H HOCH3
N
N

O
H2N
CH3 H2N
m/z: 144.07 (100.0%)
m/z: 175.09 (100.0%)

sumber (Sukesh N. Sinha,2003)

5. Metode desorpsi medan (field desorption, FD)
 Spektrum, sumber : (Heinen, Giessmann and Röllgen, 1977)
  Fregmentasi

NH O

H2N C NH(CH2)3 CH C

NH2 OH

m/z: 174.11 (100.0%)

sumber (H. J. Heinen,1977)

6. Metode ionisasi kinetic medan (field ionization kinetic, FIK)

 Spektrum, sumber : (Fenselau, Wang and Brown, 1970)
 Fregmentasi
O O

HN NH

O N N O
H H
m/z: 252.09 (100.0%) O

HN
-
O N
NH H
-

O
O

NH

O O
N O
H

NH m/z: 126,04

HN N O
H
m/z: 209,08

sumber (C. FENSELAU, 1970)

7. Metode ionisasi
 Spektrum, sumber : (Robb, Covey and Bruins, 2000)

 Fregmentasi
O

F
NH

N O
H
m/z: 130.02 (100.0%)
sumber (Damon B. Robb, 2000)
 8. GC-MS
 Spektrum, sumber : (Tseng and Lin, 2002)

 Fragmentasi

H2C COOH H2C COO H2C COO

ESI -CO2
HOOC C OH HOOC C OH H C OH
-H
H2C COOH H2C COOH H2C COOH

m/z: 191.02 (100.0%)

O
O
HC COO
C -CHCH HC C
H2O
H C
HC O O
HC
C H2C COOH
C C
H
m/z: 129.02 (100.0%)
O O

m/z: 84.99 (100.0%) m/z: 111.01 (100.0%)

sumber (MU-CHANG,2001)

DAFTAR PUSTAKA

Argia, T., Yu, R. K. And Miyatake, T. (1984) ‘Characterization Of Gangliosides By Direct Inlet
 Chemical Ionization Mass Spectrometry’, Journal Of Lipid Research, 25(10), Pp. 1096–
1101.
Fenselau, C., Wang, S. Y. And Brown, P. (1970) ‘Field Ionization Mass Spectra Of
Photopolymers Of Thymine’, Tetrahedron, 26(24), Pp. 5923–5927. Doi: 10.1016/0040-
4020(70)80029-1.
Heinen, H. J., Giessmann, U. And Röllgen, F. W. (1977) ‘Field Desorption Of Electrolytic
Solutions Using Untreated Wire Emitters’, Organic Mass Spectrometry, 12(11), Pp. 710–
715. Doi: 10.1002/Oms.1210121112.
Pellegrini, M. Et Al. (2002) ‘Rapid Screening Method For Determination Of Ecstasy And
Amphetamines In Urine Samples Using Gas Chromatography-Chemical Ionisation Mass
Spectrometry’, Journal Of Chromatography B: Analytical Technologies In The
Biomedical And Life Sciences, 769(2), Pp. 243–251. Doi: 10.1016/S1570-
0232(01)00586-4.
Robb, D. B., Covey, T. R. And Bruins, A. P. (2000) ‘Atmospheric Pressure Photoionization: An
Ionization Method For Liquid Chromatography-Mass Spectrometry’, Analytical
Chemistry, 72(15), Pp. 3653–3659. Doi: 10.1021/Ac0001636.
Sinha, S. N. And Dua, V. K. (2004) ‘Fast Atom Bombardment Mass Spectral Analysis Of Three
New Oxidative Products Of Primaquine’, International Journal Of Mass Spectrometry,
232(2), Pp. 151–163. Doi: 10.1016/J.Ijms.2003.11.013.
Steckel, A. And Schlosser, G. (2019) ‘An Organic Chemist’s Guide To Electrospray Mass
Spectrometric Structure Elucidation’, Molecules, 24(3), Pp. 1–11. Doi:
10.3390/Molecules24030611.
Tseng, M. C. And Lin, J. H. (2002) ‘Determination Of Sildenafil Citrate Adulterated In A
Dietary Supplement Capsule By LC/MS/MS’, Journal Of Food And Drug Analysis,
10(2), Pp. 112–119.