This study explored using the blood protein biomarkers GFAP and UCH-L1 for early diagnosis of traumatic brain injury (TBI) during the first week after injury. Proteomic analyses of GFAP and UCH-L1 levels were conducted on study participants and correlated with clinical and imaging findings. The study found that GFAP is a specific blood biomarker for astroglial injury while UCH-L1 is involved in ubiquitin protein processing in the brain. Elevated levels of these biomarkers were associated with CT abnormalities indicating brain injury.
This study explored using the blood protein biomarkers GFAP and UCH-L1 for early diagnosis of traumatic brain injury (TBI) during the first week after injury. Proteomic analyses of GFAP and UCH-L1 levels were conducted on study participants and correlated with clinical and imaging findings. The study found that GFAP is a specific blood biomarker for astroglial injury while UCH-L1 is involved in ubiquitin protein processing in the brain. Elevated levels of these biomarkers were associated with CT abnormalities indicating brain injury.
This study explored using the blood protein biomarkers GFAP and UCH-L1 for early diagnosis of traumatic brain injury (TBI) during the first week after injury. Proteomic analyses of GFAP and UCH-L1 levels were conducted on study participants and correlated with clinical and imaging findings. The study found that GFAP is a specific blood biomarker for astroglial injury while UCH-L1 is involved in ubiquitin protein processing in the brain. Elevated levels of these biomarkers were associated with CT abnormalities indicating brain injury.
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Judul : Ubiquitin C-Terminal Hydrolase-L1 During the First Week After a Traumatic Brain Injury: Correlations With Clinical and Imaging Findings