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Cuidados Preoperatorios en Ginecologia
Cuidados Preoperatorios en Ginecologia
Cuidados Preoperatorios en Ginecologia
OBSTETRICS, GYNAECOLOGY AND REPRODUCTIVE MEDICINE 22:2 38 Ó 2011 Elsevier Ltd. All rights reserved.
REVIEW
Consent
Obtaining consent could be performed in the gynaecological American society of anaesthesiologists (ASA) physical
outpatient clinic at the decision for certain procedure. A more status classification
appropriate time for this would be at the preassessment C A normal healthy patient
appointment, when the patient has had time to weigh her C A patient with mild systemic disease
options, collate the provided information in outpatient clinic C A patient with severe systemic disease
such as written materials and DVDs, and discuss with family, C A patient with severe systemic disease that is a constant threat
friends and GP. This gives opportunity for questions or uncer- to life
tainties to be addressed and ensures that through a process of C A moribund patient who is not expected to survive without the
informed and shared decision making, the patient has been fully operation
informed and understands the potential risks, benefits, alterna- C A declared brain-dead patient whose organs are being removed
tive treatments and recovery paths. for donor purposes
The Royal College of Obstetricians and Gynaecologists has
issued guidance on the process of consent. The risks and likeli- Table 2
hood of complications with the proposed procedure should be
portrayed in a way that is easy to be understood. Risk should be
Plain chest X-ray
ideally quantified as a frequency with the use of numerical aids
Resting electrocardiogram (ECG)
rather than percentages (Table 1).
Full blood count
The consent should include any further procedure that might
Haemostasis e including prothrombin time, activated
be necessary in event of complications such as laparotomy for
partial thromboplastin time and international normalized
visceral or vascular damage that occurs during laparoscopy.
ratio (INR)
Any procedure that the patient would object to needs to be
Renal function (including tests for potassium, sodium,
specifically and clearly documented.
creatinine and/or urea levels)
Consent for treatment prior to surgery, including the benefits,
Random blood glucose
potential risks and management of intraoperative complications
Urine analysis (urine dipstick test e test for pH, protein,
should be taken by someone, capable of performing the proce-
glucose, ketones, blood/haemoglobin)
dure or has good experience of the procedure. The operating or
Blood gases e for ASA grades 2 and 3 only
supervising surgeon should confirm this on the day of operation.
Lung function (peak expiratory flow rate, forced vital
Preoperative test capacity and forced expiratory volume) e for ASA grades 2
and 3 only.
Preoperative tests should be considered only after the assessment Prior to surgery, women of childbearing age should have
of the patient. Performing unnecessary and expensive investiga- a pregnancy test performed with woman’s consent as certain
tions for healthy, asymptomatic patients should be avoided, as this procedures carry anaesthetic and surgical risk to the fetus.
could potentially add to the anxiety levels and increase the cost,
without having positive effect on the management of the patient. MRSA screening
According to the National Institute for Clinical Excellence Methicillin-resistant Staphylococcus aureus (MRSA) is resistant to
(NICE) preoperative tests should be undertaken with the commonly used anti-staphylococcal antibiotics such as penicillins,
consideration of patient’s age, physical American Society of
Anaesthesiologists (ASA) status (Table 2), the grade and extent
of the surgery (Table 3) and the presence of co-morbidity.
The abridged version of the NICE guidance presents the
Classification of surgical interventions in different
different combinations of these four parameters and the appro-
intensity (and risk) categories
priate tests needed.
The preoperative investigation that might be required and Grade 1 (minor) Excision of lesion of skin; drainage of breast
considered by NICE include: abscess; carpal tunnel release; nasal septum correction
Grade 2 (intermediate) Primary repair of inguinal hernia; excision of
varicose vein(s) of leg; tonsillectomy/adenotonsillectomy; knee
arthroscopy; endoscopic bladder procedure; eye lens substitution
Presenting information on risk Grade 3 (major) Total abdominal hysterectomy; endoscopic resec-
tion of prostate; lumbar discectomy; thyroidectomy; diaphragmatic
Very common 1/1e1/10 A person in family
hernia repair; operations on trachea; prosthetic femoral head
Common 1/10e1/100 A person in street
replacement
Uncommon 1/100e1/1000 A person in village
Grade 4 (majorþ) Total joint replacement; lung operations; radical
Rare 1/1000e1/10,000 A person in small town
neck dissections; organ transplantations
Very rare <1/10,000 A person in large town
Neurosurgery
Royal College of Obstetricians and Gynaecologists Cardiovascular surgery
Table 1 Table 3
OBSTETRICS, GYNAECOLOGY AND REPRODUCTIVE MEDICINE 22:2 39 Ó 2011 Elsevier Ltd. All rights reserved.
REVIEW
cephalosporins, erythromycin and ciprofloxacin. MRSA potentially commonly used are Aspirin and Clopidogrel both of which
could cause sepsis, endocarditis, and pneumonia, particularly in inhibit platelet aggregation and increase the perioperative
elderly and immuno-compromised patients. bleeding risk. This risk increases to around 1% with their
In accordance with the policy issued by the Department of simultaneous application/dual regimen.
Health (DH) and Regional Strategic Health Authority (SHA), all Both Aspirin and Clopidogrel can be continued through the
patients admitted for elective surgery, including day case operative period if the risk of bleeding does not exceed the
admissions should have MRSA status checked. Usually this is benefits.
performed at the preassessment appointment. It is the clinician’s However in gynaecological surgery usually these agents are
responsibility to follow up this result prior to proceeding with the stopped 5e7 days prior to the day of operation, which corre-
surgical intervention. spond to the platelet half-life.
If a patient is found to be MRSA positive, treatment should be In cases of significant haemorrhage, pooled platelet trans-
started and the patient’s GP notified. fusion or antifibrinolytic agent such as tranexamic acid could be
The decision to proceed with the operation would depend on considered.
the clinical urgency, the type and extent of surgery and the
potential risk of MRSA infection. Oral contraceptive pill and hormone replacement therapy
If surgery is necessary in an MRSA positive patient, precau- (HRT)
tions are undertaken such as theatres need to be informed, the It is generally advised that the combined oral contraceptive pill
patient should be last on the operative list and there should be should be stopped 4e6 weeks prior to major surgery, as this
a side room available for the care of the patient in the post- increases the risk of venous thromboembolism. Alternative
operative period. methods of contraception need to be put in place. The risks of
pregnancy need to be balanced with the risk of venous throm-
Venous thromboembolism (VTE) assessment boembolism prior to discontinuing oral contraception.
Following gynaecological surgery there is 16% incidence of deep It is not necessary to discontinue oral contraception for minor
venous thrombosis (DVT) and 1% of symptomatic pulmonary surgery, as the risk of venous thromboembolism is low with
embolism (PE) without thromboprophylaxis. It is a mandatory early mobilization and appropriate hydration. The progesterone
requirement now in the UK that all patients undergo venous only pill increases minimally the risk for VTE; therefore this does
thromboembolism risk assessment prior to surgery and hospital not need to be stopped prior to an operation.
admission. Depending on the calculated risk, patients receive HRT equally adds minimally to the risk of venous thrombo-
gradual compression thromboembolitic stockings or low molec- embolism. The age group taking HRT will likely require
ular weight heparin (LMWH) either alone or in combination. prophylactic thromboprophylaxis; therefore it is not necessary to
LMWH (Enoxaparin, Tinzaparin) have wide application in view stop the HRT prior to surgery.
of their relatively short half-life, easy administration and lack of
need for close therapeutic monitoring. Cardiovascular disease drugs
The general recommendation is for all anti-hypertensive, anti-
Drug history and current medications arrhythmic and diuretic agents for the treatment of cardiovas-
Careful evaluation of patient’s current medications should be cular disease to be continued as usual in the perioperative period,
undertaken, as some medications need to be reconsidered or including the day of surgery.
stopped prior to surgery. Patients should be advised on which
medication to omit or take on the day of surgery. Respiratory disease drugs
Same principles apply for anti-asthmatic and chronic obstructive
Anticoagulant therapy pulmonary disease (COPD) agents. Discontinuing these medica-
Considering surgery on patients on oral anticoagulants is a risk- tions would increase the risk of exacerbation of the chronic
benefit balance. The major concerns are of haemorrhage versus condition; therefore their use is advocated throughout the peri-
the risk of thromboembolism. operative period.
Prior to major surgery in most cases, patients on long-term
oral anticoagulant therapy will need to be converted to low Anti-epileptic medications
molecular weight heparin (LMWH), aiming for the international There is increased risk of seizures in the perioperative period in
normalized ratio (INR) to be <1.5 on the day of the procedure. patients with seizure disorders. All anti-epileptic agents should
Following the operation, when the risk of bleeding is low, the be continued throughout, including the day of surgery.
oral anticoagulant needs to be re-introduced together with the
low molecular weight heparin (LMWH), until the INR reaches Diabetes
therapeutic range. Patients with diabetes should ideally be planned to be first on the
This process could contribute to delayed discharge, therefore operating list to decrease the nil by mouth period and minimize
it is important to have preoperative plans in place and close the glucose metabolism disruption.
collaboration with GP and anticoagulant clinic. In patients with type 1 insulin-dependant diabetes, undergoing
major surgery, their usual insulin is omitted on the day of surgery
Antiplatelet medications and an intravenous ‘sliding scale’ insulin regimen started.
Vast majority of patients receive antiplatelet agents as a part of In the postoperative period the usual insulin regimen is
a prophylaxis or treatment for cardiovascular disease. Most restarted once oral feeding is re-established.
OBSTETRICS, GYNAECOLOGY AND REPRODUCTIVE MEDICINE 22:2 40 Ó 2011 Elsevier Ltd. All rights reserved.
REVIEW
In type 2 non-insulin dependant diabetes, the oral hypo- When this is not feasible, transverse suprapubic incision is the
glycaemic medications are omitted on the day of surgery. Insulin norm unless suspected/diagnosed ovarian cancer or difficult
sliding scale is considered in cases of major surgery, capillary surgery is anticipated, when midline incision is used.
blood glucose level of more than 12 mmol/l, ketonuria or if delay
in establishing enteral feeding following the operation is Drains: the routine use of drains is not practiced, as this does not
anticipated. reduce the postoperative morbidity. On the contrary they
increase the risk of infection, decrease patient’s mobility and
Day-case surgery prolong hospital admission.
They have a role to play in certain high risk and complex
Day surgery is the admission of selected patients to hospital for procedures and should be dictated by clinical need.
a planned surgical procedure and discharge home on the same
day. The day surgery programme has been a key stand of the Antibiotic prophylaxis: it is commonly used in gynaecological
NHS modernization for the last 10 years. The NHS aims for 75% surgery as part of the aim to reduce postoperative infection rate.
of all elective procedures to be performed as day cases (Day The decision for antibiotic administration depends on the
surgery: Operation guide. Department of Health, 15 August patient’s co-morbidities, allergy status, extent of the procedure,
2002). local antimicrobial policy and surgeon’s preference.
With the appropriate patients’ selection, the benefits of day- The World Health Organization (WHO) Safer Surgery check-
case surgery are: list recommends, to achieve maximum antibiotic tissue concen-
Faster recovery at the patient’s own home tration, antimicrobial prophylaxis should be given 60 min or less
Reduced risk of cancellations due bed shortage before “knife to skin”.
Reduced risk of hospital acquired infections Minor procedures involving instrumentation of the uterus
Reduction in waiting lists (hysteroscopy, insertion of intra-uterine device) do not require
In-patients bed availability for major cases the routine use of antibiotics, however in the high-risk group of
Cost-effective health care. sexually transmitted infection (age < 20, nulliparity, multiple
The aim to use more and more minimally invasive surgical sexual partners), screening should be offered prior to surgery. If
techniques, as part of the enhanced recovery programme, has the results are not known, postoperative Chlamydia prophylaxis
added to the goal of performing day-case surgery. In gynaeco- with doxycycline or azithromycin should be given. Similar
logical surgery many of the procedures can be performed lapa- principles apply for surgical termination of pregnancy with the
roscopically if appropriate. Laparoscopy has the benefits of less addition of oral metronidazole.
surgical trauma, small incision, less postoperative pain, faster
recovery. Patients undergoing laparoscopic surgery have shorter Hypothermia: body temperature should be maintained above
hospital stay, are able to return sooner to their normal activities 36.5 C to decrease postoperative complications. Routine moni-
and have higher satisfaction from the overall care. toring of patient’s temperature in theatre, the use of air-warming
system and intravenous fluid warmers can prevent hypothermia.
Intraoperative care Information and education of the patients regarding hypo-
Anaesthetic factors thermia, encouraging them to bring extra clothing to hospital and
Meticulous intraoperative fluid balance and optimal analgesia are to report feeling cold to staff adds to prevent hypothermia in the
keys for smooth postoperative recovery and shorter hospital stay. pre- and postoperative period.
Regional anaesthetic techniques and nerve blocks have been
recommended over the use of long-acting opiates. Postoperative period
For postoperative pain control in particular in open abdominal
In the postoperative period the emphasis is on the patients
surgery the use of epidural analgesia or when not appropriate
receiving optimal care to aid with the recovery.
patient-controlled analgesia (PCA) seems to have good effect on
convalescence.
Pain management
The use of regular paracetamol and non-steroidal anti-
Optimizing pain relief in the postoperative period aids signifi-
inflammatory agents can be effective and decreases the use of
cantly with the recovery process, early nutrition and rehabilita-
opiates.
tion. In most hospitals there are Trust-established guidelines on
Nausea and vomiting postoperative pain management and the use of step-down
Intraoperative anti-emetics could be considered as appropriate, analgesia.
however their routine use is not practiced. In major abdominal surgery, especially with midline lapa-
Anti-emetics as first line or “as required” should be prescribed rotomy, combined regimen of analgesia for the first 24e48 h is
on the patient’s drug chart and administered at first symptoms. preferred with either a thoracic epidural, spinal or patient-
controlled analgesia. Mobile epidural could be considered to
Surgical factors allow early mobilization. Spinal analgesia has advantages of
Incision: as mentioned previously the aim should be at per- lower insertion rate failure, lower risk of complications and not
forming surgery with minimal access techniques when possible, affecting patient’s mobility on the morning following surgery.
to reduce the surgical trauma to the patients and aid their faster Step-down analgesia is contemplated as part of the recovery
recovery. process with combination of regular paracetamol, a non-steroidal
OBSTETRICS, GYNAECOLOGY AND REPRODUCTIVE MEDICINE 22:2 41 Ó 2011 Elsevier Ltd. All rights reserved.
REVIEW
anti-inflammatory medication and mild opioid such as codeine 4e6 Units of blood considered. Initial fluid replacement is per-
sulphate, unless contraindicated. For breakthrough pain stronger formed with the use of crystalloids as they have good effect on the
opioid such as oramorph or oxycodone could be used. extra-cellular compartment, and colloids to replace intravascular
Anti-emetics and stool softeners should be prescribed to volume. Blood transfusion should be commenced as soon as
minimize side effects. possible in cases of significant blood loss. Early haematology
involvement is recommended in case of major haemorrhage, as
Nutrition there is increased risk of consumptive coagulopathy.
Early postoperative nutrition is encouraged as this has been
shown to reduce the postoperative hospital stay with no effect on Postoperative infection
the incidence of ileus or vomiting. This can be started with sips of Single episode of raised temperature of 37.6 C and above in the
water and built up as tolerated by the patient. In addition, energy immediate postoperative period usually resolves spontaneously.
drinks could be used in the immediate postoperative period. However if the pyrexia persists on consecutive assessments
Where there is delay in feeding or previous malnutrition, the and beyond 24 h of surgery, site of infection should be sought.
input of dietician is important to consider further supplements or Review of the history and full clinical assessment should take
parenteral feeding in severe cases. place including examination of chest, heart sounds, abdomen,
wound appearance and legs/calves to look for signs of DVT.
Early rehabilitation FBC, U&E, LFTs and CRP should be requested for evaluation
Early mobilization aids with decreasing the risk of venous of inflammatory markers, look for anaemia and exclude renal or
thromboembolism, abdominal distension secondary to gas liver function compromise.
entrapment and promotes gut function. This also empowers the Blood cultures, mid-stream urine or catheter specimen,
patients and actively involves them in the process of enhanced wound swabs or sputum for culture if indicated should be sent
recovery. The physiotherapists play a major role in the reducing for culture and sensitivity.
hospital stay and improving patient’s satisfaction and shortening If wound infection is suspected antibiotic of choice is Flu-
the period of returning to normality. Chest physiotherapy in the cloxacillin or a macrolide in case of Penicillin allergy such as
postoperative period significantly reduces the incidence of chest Clarithromycin.
infection in particular in elderly patients undergoing major Initially if no source of infection is identified, empiric broad-
gynaecological surgery. spectrum intravenous antibiotic could be started. As soon as
Patients could be encouraged once able to change in to their culture sensitivity results are available, the choice of antibiotic
usual clothes to aid mobilization by reducing the feeling of should be reviewed to ensure the most appropriate treatment is
discomfort of the hospital environment. administered. Close collaboration with microbiology sometimes
is essential in the correct management of postoperative pyrexia.
Bladder care
Imaging techniques such as chest X-ray, USS or CT scan could
Depending on the type of surgery and anaesthesia used, an
aid in identifying localized source of infection such as pelvic
indwelling catheter is sited to monitor urine output and aid with
collection, abscess, pneumonia, atelectasis etc.
the bladder emptying in the immediate postoperative period
without the need to mobilize. In recent practice the aim is to
Injury to internal organs
remove catheters as soon as possible after surgery to help with the
Bowel: bowel injury occurs rarely in gynaecological surgery with
early rehabilitation and reduce the risk of urinary tract infection.
incidence between 0.3% and 0.8%. Risk factors include major
Catheter removal after major surgery requires calculating residual
gynaecological oncology surgery, the presence of endometriosis,
bladder volumes to ensure complete voiding. Residuals higher
previous pelvic inflammatory disease, abdominal or pelvic
that 150 ml may require recatheterization and discharge of the
radiotherapy.
patient with indwelling catheter and a leg bag. Plan for review in
Suspicion for this is raised in cases of persistent nausea,
7e10 days for a trial without a catheter is adopted and if this fails
vomiting, abdominal distension and commonly with the absence
then intermittent self-catheterization is taught.
of bowel sounds.
CT imaging usually helps with the diagnosis and initial
Postoperative complications
management is of stabilizing the patient by rehydration, insertion
Bleeding of naso-gastric tube and starting broad-spectrum antibiotics.
Intra-abdominal bleeding in the immediate postoperative period Multidisciplinary team involvement is necessary for consid-
is a recognized complication of abdominal surgery, despite eration of re-exploration.
meticulous surgical technique and careful intraoperative atten-
tion to haemostasis. Injury to urinary tract
Sudden drop in the blood pressure associated with marked This includes injury to the urinary bladder and ureters and is
tachycardia and deterioration in the patient’s condition should a recognized complication of hysterectomy. The incidence of
raise the suspicion of postoperative bleeding and medical review bladder injury ranges between 0.2% and 1.8% and that of
should be performed as a matter of emergency. ureteric injury between 0.03% and 1.5%.
Assessment should be performed using ABC approach with the Common sites of ureteric injury are at the level of the
aim to initially stabilize the patient and consider re-exploration. infundibulo-pelvic ligament, the uterosacral ligament where the
The decision for the latter is taken at a senior level. Large bore ureter crosses under the uterine artery and at ureteric insertion
intravenous access should be obtained and FBC and cross match of into the bladder.
OBSTETRICS, GYNAECOLOGY AND REPRODUCTIVE MEDICINE 22:2 42 Ó 2011 Elsevier Ltd. All rights reserved.
REVIEW
Many of these injuries are not recognized until the post- Delivering enhanced recovery: helping patients to get better sooner after
operative period. surgery. Department of Health, March 2010.
Ureteric injury usually presents with loin pain, pyrexia, Douketis JD, Berger PB, Dunn AS, et al. The perioperative management of
raising creatinine and urea levels, reduced or absent urine output antithrombotic therapy: American College of Chest Physicians
in case of bilateral ureteric transection. Evidence-Based Clinical Practice Guidelines (8th edn). Chest Jun 2008;
133(6 suppl): 299Se339.
Thromboembolism MRSA screening e operational guidance. Department of Health, July
The incidence of postoperative venous thromboembolism has 2008.
significantly decreased after the implementation of mandatory National Institute for Clinical Excellence. Clinical guidance: CG3. Preop-
VTE risk assessment and thromboprophylaxis. erative tests. The use of routine preoperative tests for elective
However if suspicion of DVT or PE is raised in the post- surgery; NICE, August 2003. http://www.nice.org.uk/pdf/PreopTests_
operative period, careful assessment and further investigations Apps.pdf Association of Anaesthetists of Great Britain and Ireland.
will be necessary. Doppler ultrasound will help in the diagnosis Pre-operative assessment. The role of the anaesthetist; 2001.
of a DVT (sensitivity of 97%). However in cases with high National Institute for Clinical Excellence. Clinical guidance: CG46. Venous
suspicion and negative venous ultrasound, therapeutic dose of thromboembolism: reducing the risk of venous thromboembolism
LMWH should be continued and USS repeated in 1 week’s time. (deep vein thrombosis and pulmonary embolism) in patients under-
Computerized tomography pulmonary angiogram (CTPA) is going surgery. London: NICE, April 2007.
the recommended modality in the investigation of suspected National Institute for Clinical Excellence. Clinical guidance: CG65.
pulmonary embolism. VQ-scan could be considered in cases of Management of perioperative hypothermia in adults. London: NICE,
a normal chest X-ray and the absence of cardiopulmonary disease. April 2008.
If PE is confirmed then therapeutic dose of LMWH should be Royal College of Obstetricians and Gynaecologists. Clinical governance
started and converted to oral anticoagulant (Warfarin) once the advice no.6. Obtaining valid consent. London: RCOG, December 2008.
risk of postoperative bleeding is low. Anticoagulant clinic referral Royal College of Obstetricians and Gynaecologists. Clinical guidance no.
should be made for continuation of therapy for 3e6 months and 19. Hormone replacement therapy and thromboembolism. London:
further follow. RCOG, May 2011.
Discharge
In accordance with the overall tendency of reducing hospital
stay, a planned discharge date or expected hospital stay should
Practice points
be discussed with the patient at the preadmission assessment.
This would help the patient to make relevant arrangements and C Preoperative assessment is based mainly on history and
also highlight social problems prior to admission, which could
examination with avoidance of routine preoperative tests for
inevitably delay discharge. It is important that patients are dis-
healthy individuals
charged when this is clinically appropriate and they feel that they C The presence of concurrent disease will require liaison with
could safely cope at home and have the necessary support.
anaesthetist and other specialists
A clear discharge summary should be provided with infor- C Choice of best procedure, adequate access, use of minimally
mation on the perioperative events, immediate management,
invasive techniques where possible, minimizing use of drains,
analgesia and follow up.
routine antibiotic prophylaxis and avoiding hypothermia are
Patients should be given information and contact numbers in
widely practiced
case of an emergency arising from their surgery. A C Adequate pain control, early nutrition and early rehabilitation
aid with fast recovery
C Daily reviews for early identification of potential postoperative
FURTHER READING complications and their prompt management
American Society of Anesthesiologists; ASA relative value guide, http:// C Patients should receive postoperative advice on expected
www.asahq.org/clinical/physicalstatus.htm; 2002. recovery rates, levels of discomfort, activities
Day surgery: operation guide. Department of Health, August 2002.
OBSTETRICS, GYNAECOLOGY AND REPRODUCTIVE MEDICINE 22:2 43 Ó 2011 Elsevier Ltd. All rights reserved.