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Drug Study Amoxicillin PDF
Drug Study Amoxicillin PDF
Name of Patient Anding, Jessica Donaire Age 5 yrs. 5 months Height 105.5 cm
Diagnosis R/O conjunctivitis secondary Sex Female Weight 17 kg
to trauma
Doctor Dr. Tipgos Date of Admission Not yet admitted Body Build sthenic
Drug Data Classification Mechanism of Action Indication Contraindications Adverse Reaction Nursing Responsibilities
^c eneric Name Therapeutic: ^c Pharmacokinetics ^c eneral Hypersensitivity CNS: Agitation, ^ cBefore
Antibiotic A Indications to amoxicillin or anxiety, behavior Patients with
amoxicillin trihydrate Well absorbed from To treat ear, nose, its com- changes, mononucleosis
(amoxycillin) Pharmacologic duodenum (75±90%). throat, U tract, ponents confusion, shouldn¶t
aminopenicillins More resistant to acid skin, ^ cPrecaution dizziness, receive amoxicillin
Trade Name inactivation than and soft-tissue Severe renal insomnia, because this class of
Amoxil, Apo-Amoxi other penicillins infections caused reversible drugs may cause an
insufficiency (Ļ
(CAN), DisperMox, D by sus- hyperactivity, erythematous rash.
dose if CCr <30
Moxatag, Novamoxin cDiffuses readily into ceptible gram- seizures Use drug cautiously in
mL/min)
(CAN), Nu-Amoxi most body tissues and positive and CV: patients with hepatic
(CAN), Polymox, fluids. CSF gram- Infectious Hypersensitivity impairment.
Trimox, Wymox penetration increased mononucleosis, vasculitis Monitor hepatic and
negative acute
when meninges are EENT: Black, renal function and CBC,
organisms, To lymphocytic
^c Patients Dose inflamed. Crosses treat tonsillitis
hairy tongue; as ordered, in patients
Suspension for 7 days placenta; enters breast leukemia, or mucocutaneous on prolonged therapy.
or pharyngitis cytomegaloviru
^c Minimum Dose milk in small amounts caused by
candididasis; use cautiously in breast-
Children age 12 s infection (Ĺ tooth feeding and elderly
Streptococcus risk of rash)
wk and over M&E pyogenes, To discoloration patients.
weighing less than 70% excreted treat lower O cc I: Diarrhea, Expect to start therapy
20 kg. 20 mg/kg unchanged in the Has been used diarrhea related to before culture and
respiratory
daily in divided urine; 30% safely Clostridium sensitivity test results
tract infec
doses every 8 hr metabolized by the difficile, elevated are known.
tions caused
^c Maximum Dose liver liver enzymes, as ordered.
by susceptible ^ cDrug interaction
500 mg every 8 hr gram-positive hemorrhag- ic or PATIENT TEACHIN
-drug to drug
or 875 mg every ^c Onset and gram- allopurinol:
pseudomembrano Tell patient to refrigerate
12 hr Unknown us colitis, reconstituted sus-
negative Increased risk of
^c Availability and Peak jaundice, hepatic pension and to shake
organisms, rash
color Unknown dysfunction, well before each use.
CAPSULES, ^c Duration\ Treatment of chloramphenicol, nausea, vomiting When amoxicillin
CHEWABLE 6±8 hr » Skin and skin erythromycins, U: Crystalluria, suspension is prescribed
TABLETS, ORAL ^c Drug Half Life structure sulfon- amides, vaginal mycosis for a child, instruct
SUSPENSION, Neonates: 3.7 hr; infections tetracyclines: HEME: parents to place it
PEDIATRIC Infants and Children: Reduced Agranulocytosis, directly on child¶s
DROPS, POWDER 1±2 hr; Adults: 0.7± bactericidal effect anemia (including tongue to swallow. If
OR ^c Patients of amoxicillin hemolytic this doesn¶t work, tell
1.4 hr
TABLETS FOR Actual methotrexate: anemia), parents to mix dose of
ORAL Indication Increased risk of eosinophilia, suspension with formula
SUSPENSION, Treatment of methotrex- ate granulo- cytosis, or cold drink (milk, fruit
TABLETS » Skin and skin toxicity leukopenia, juice, ginger ale, water)
^c Routes of structure oral contraceptives thrombocytopenia and have child drink it
administration infections with estrogen: , immediately.
P.O. Possibly thrombocytopenic Instruct patient using
76 purpura DisperMox tablets to
amphetamine SKIN: Erythema place one tablet and
sulfate multiforme, about 2 teaspoonfuls of
erythematous water in a glass, drink
reduced maculopapular entire mix ture, add
effectiveness of rash, generalized more water to the glass,
contraceptive exanthe- matous and drink again to
probenecid: pustulosis, ensure delivery of full
Increased Stevens-Johnson dose.
amoxicillin effects syn- drome, toxic During
epidermal Be aware that chewable
necrolysis, tablets and tablets for
urticaria Other: oral suspension contain
Allergic reaction, phenylalanine.
anaphylaxis, Tell patient to chew or
serum crush chewable tablets
sicknesslike and not to swallow them
reaction (such as whole.
arthralgia, Don¶t confuse
arthritis, fever, amoxicillin tablets with
myalgia, rash, and amoxicillin tablets for
urticaria) oral suspension
(DisperMox). They¶re
not interchangeable.
If allergic reaction
occurs, stop
amoxicillin immediately
and provide emergency
care as indicated and
ordered.
Monitor patient for
superinfection. If it
occurs, expect to
discontinue drug and
provide treatment
After
Teach patient to report
adverse reactions
notify prescriber if
infection worsens or
doesn¶t improve after 72
hours.
To prevent infection
from recurring, urge
patient to take
amoxicillin for full
length of time
prescribed, even if he
feels better.
Urge patient to tell
prescriber about diar-
rhea that¶s severe or
lasts longer than
3 days. Remind patient
that watery or bloody
stools can occur 2 or
more months after
antibiotic therapy and
may be serious,
requiring prompt
treatment.
Monitor patient closely
for diarrhea, which may
indicate
pseudomembranous
colitis
Expect treatment that
lasts at least 10 days for
hemolytic streptococci
infections.