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Disease Jaundice
Disease Jaundice
Disease Jaundice
PORTION
JAUNDICE
Definition:
An excessive level of accumulated bilirubin in blood and is characterised by “hyper
bilirubinemia” or “Icterus”.this may be as the result of increased unconjugated and
conjugated bilirubin level above normal.
Jaundice comes from the French word “Jaune” which means yellow.
Jaundice is the clinical term used for the yellowish discoloration of the mucus
membrane and skin due to increase serum bilirubin level more than 4-5 mg/dl in the
new born.
Prevalence
Signs of Neonatal Jaundice are seen within the first three days of birth in 80% of
preterm babies and 60% of full-term infants
Jaundice persisting beyond 14 days of age (prolonged jaundice) can (rarely) be a sign of serious
underlying liver disease (Hussein, 1991). Jaundice persists beyond 14 days in 15-40% of breastfed
infants, depending on the series studied (Hannam, 2000). A prospective study of all 7139 term
infants born at King’s College Hospital (London) between January 1997 and June 1998 (Hannam,
2000) found 154 with prolonged jaundice, one of which had conjugated hyperbilirubinaemia (0.14
per 1000 live births).
Another study of 3661 babies in Sheffield (Crofts, 1999) found 127 who were jaundiced at 28 days, of
which 125 were breastfed (9.2%).
Although preterm infants, whose livers are more immature, have prolonged jaundice
more commonly than term infants (Fenton, 1998) there appear to be no studies of
incidence in this group (Lucas, 1986).
Etiology
Signs of Neonatal jaundice are seen within the first three days of birth in 80% of preterm
babies and 60% of full term infants.The journal of Paediatrics reports a retrospective
study,which observed that the incidence of Jaundice is higher in breast feed babies than in
the formula feed ones.
Causes of jaundice:
Physiological jaundice
Pathological jaundice associated with liver disease
Rh and ABO incompatibilty
Inherited cause of hemolytic disease i.e.glucose 6 phospate dehydrogenase
deficiency
Erythroblastosis Fetalis
Breast milk jaundice
Jaundice due to sepsis
Hemolysis due to drugs (quinine),poison(snake venom)
Congenital biliary atresia and obstructive jaundice
Inborn errors of metabolism:Galactosemia,Hypothyroidism,glucuronyl
transferase deficiency
Types of jaundice:
I.Physiological jaundice:
It is common in newborn babies. It usually becomes noticeable during the baby's first three
to five days of life. It disappears as the baby's liver matures. This type of jaundice is not
harmful.
II.Hemolytic jaundice:
This type of jaundice develops when there is Rh incompatibility and ABO in compatibility
between the mother and the fetus.
Rh incompatibility occurs when the mother is Rh negative and the fetus is Rh
positive, having inherited gene for the Rhesus factor from his/her parents
ABO incompatibility may present if the mother has blood group “O” and baby has
type “A “or “B” .then the mother makes Anti A or Anti B type anti bodies of the IgG glass and
cross the placenta causing destruction of the baby’s red blood cells.
III.Pathological Jaundice:
In some situation however there is so much billirubin in baby’s blood that it can be harmful
.This condition is called Pathological Jaundice.If the level of bilirubin becomes very high ,it
may affect some of the baby ‘s brain cells. This may cause a baby to be les active.In rare
cases ,a baby may have seizures (convulsions).Pathological jaundice may lead to
deafness ,cerebral palsy and /or mental retardation. Pathologic jaundice can occur in
children or adults. It arises for many reasons ,including blood incompatibilities, blood
diseases, genetics syndromes ,hepatitis , cirrhosis ,bile duct blockage ,other liver diseases
,infections ,or medications.
Jaundice may be related to inadequate liver function due to infection like TOCH and sepsis
or other factors.
I. Within 36 hours:
Usually pathological jaundice appears within 36 hours of life. This may involve
haemolytical jaundice usually due to Isoimmunisation, G6PD deficiency and other
congenital infections.
Pathophysiology:
Bilirubin is one of the breakdown product of haemoglobin result from Red Blood
Cell(RBC) destruction.When RBC is destroyed ,the breakdown product are release
into the blood circulation where haemoglobin splits into two fraction:hame and globin.
The globin (protein) portion is used by the body and the heme is converted to
conjugated bilirubin, an insoluble substance to albumin.
In liver ,the bilirubin is detached from the albumin molecule in presence of enzyme
glucornyl transferase is conjugated with glucuronic acid to produce a highly
soluble ,conjugated bilirubin glucoronide ,whivh is then excreted into the bile.In the
intestine ,bacterial action reduces the conjugated bilirubin to urobilirobinogen ,the
pigment that gives the stool its characteristics color.Most of reduce bilirubin is
excreted through feces.
Normally, the body is able to maintain a balance between the destruction of RBCs
and the use and excretion of the byproducts.However, when developmental
limitation or a pathologic process interferes with this balance; bilirubin accumulates
into tissue to produce jaundice.
Diagnosis:
a. History Taking: Positive family history of jaundice and anaemia,Previous babies with
jaundice
b. Family history of neonatal or early infant deaths due to liver disease suggesting
Galactesemia.
c. Maternal drugs such as sulphonamides or antimalarial drugs causing haemolysis in baby
d. Physical examination findings: Presence of yellowish staining of sclera ,skin and mucus
membrane.
e. A blood test will confirm the raised bilirubin level and other tests such as those for hepatitis
and haemolysis are also done on the blood.
Blood serum bilirubin
Complete blood count
Liver function test and bilirubin
Prothombin time
Bleeding time
Clotting time
2069/3/28
Thyroid function Test
069/04/1
Ultrasonography :
Liver :7.8 mm with normal echotexture
Spleen: 7.2 mm with normal texture
Kidney: Mild dilatation at right kidney
Impression : spleenomegaly
Mild hydronephrosis
069/04/03
Hb 4.8
069/04/04
Cholesterol 174mg% 150-250mg%
Total Protein 6.2 6-8g%
Albumin 4.1 3.5-5.2
Bilirubin Total 21.1 0.4-0.9mg%
Bilirubin Congugate 15.3 0.4gm%
SGPT 285
SGOT 208
PT 18 sec (12 sec)
APTT 26sec (23sec)
Preventions of Jaundice:
Although jaundice cannot be totally prevented but recognition and treatment are important in
preventing bilirubin levels from rising to dangerous levels.If your baby’s color id turning more
yellow , promptly call your baby’s physician.
Feed babies frequently and don’t let them become dehydrated
With jaundice,the important thing to prevent kernicterus –toxic levels of bilirubin
accumulating in the brain. Early identification and treatment of jaundice will usually prevent
kernicterus, whatever the cause.
Treatment of Jaundice:
Most jaundice needs no treatment,but when it does,the given below treatments are possible:
1. Encourage frequent nursing ,at least 8-10 times per day and avoid pacifiers.
2. Avoid supplementation of mother’s milk with water or glucose water.If supplementation
needed due to some reason then give expressed breast milk of formula feeding
approximately 30ml/feeding for term and near term infants.
3. Halted breast feeding until bilirubin level drop in case of prlonged jaundice
4. Phototherapy (light therapy) is considered very safe and effective.Placing the baby under
blue “bililights” lights – naked in a bassinet,with his eyes covered – will often do the trick
because ultraviolet light changes the bilirubin to a form that your baby can more easily
dispose of in his urine.
5. Fibre optic blanket:another option involves wrapping the baby in a fibre optic blanket
called a bili-blanket or bili-pad
Phototherapy is usually effective,but if a baby develops a severe case of jaundice ,or his
bilirubin levels continue to rise despite phototherapy treatment ,he may need to be admitted
to the intensive care unit for a blood transfusion called an “exchange transfusion”.
9. Maintain hydration
Assess early sign of dehydration
Ensure that the baaby is fed
Encourage mother to breast fed at least every three hourly.If baby receiving
intravenous fluid or expressed breast milk ,increasethe volume of fluid by 10% of
total daily volume per day as long as the baby is under photo therapy
Maintain intake output chart
Promoting parent –infant interaction:unless jaundice is severe,photo therapy can
safely to interrupt at feeding time,allow parental visits and encourage skin to skin
contact
Monitoing bilirubin levels:The most significant decline in bilirubin level occurs in the
first 4-6 hours after initiating photo therapy so assess bilirubin periodically
Proper recording of duration and type of therapy
Complications:
a. Acute bilirubin encephalopathy
b. Kernicterus
c. Abnormal motor movement
d. Behavior disorder
e. Sensor neural hearing loss
NURSING MANAGEMENT:
Assessment:
During patient's assessment, I observed following things:
Patient's general condition.
Vital signs.
Nutritional status
Anxiety level of parents.
NURSING DIAGNOSIS:
Imbalanced Nutrition:Less than Body requirements related to inadequate intake
and diarrhoea
Impaired skin integrity related to hyperbilirubinemia and diarrhoea
Anxiety related to change in health status(patient’s mother)
Fluid volume deficit r/t poor absorption
Potential for altered growth-due to liver disease
Altered Growth and Development r/t chronic illness
Health Maintenance Altered, need for family to monitor for symptoms of increased liver
dysfunction
NURSING
CARE PLAN
SN Nursing Nursing goal Nursing intervention Rationale Evaluation
diagnosis
1. Imbalanced The client will - Record the number -Variations help identify fluctuating My goal was met the
Nutrition:Less maintain and quality of faecal intravascular volumes or changes in risk for fluid deficit was
than Body adequate vital signs associated with immune minimized.
requirements infantile body response to inflammation
-Monitor skin turgor
related to fluids -indicators of adequacy of peripheral
inadequate intake circulation and cellular hydration
and -Monitor intake output -Monitor intake and output (I &O);note
diarrhoea urine color and concerntration and
-Give water between specific gravity
breastfeeding or giving -Indicators of return of peristalsis and
a bottle readiness to begin oral intake
2. Impaired skin The integrity -Useful in monitoring effectiveness of My goal was partially
integrity related to of the baby medication,progression of met. The patient was
hyperbilirubinemia skin can be - Assess skin color healing.Changes in characteristics of quiet relieved by the
and diarrhoea maintained every 8 hours pain may indicate developing therapy but not
abcess /peritonitis,requiring prompt controlled.
medical evaluation and intervention.
-Monitor direct and
-Being informed about progress of
indirect bilirubin
situation provides emotional support,
-Change position every helping to decrease anxiety
2 hours -Relief of pain facilitates cooperation
-Massage the area that with other therapeutic interventions,
stands out -Refocuses attention, promotes
relaxation, and may enhance coping
abilities.
-Keep your skin clean -Decreases discomfort of early
and moisture intestinal peristalsis and gastric
irritation/vomiting.
3. Anxiety related to -to relieve -examine the level of Understanding promotes cooperation My goal was met the
change in health anxiety anxiety with therapeutic regimen, enhancing patient party was less
status(patient’s healing and recovery process anxious and well
mother) oriented about his
-Give information about
disease condition.
the disease process
and actions -to gain trust from the patient party
-reassure the patient
party
-Enhance the patient
general activity
4. Fluid volume maintain fluid -document and - Useful in My goal was fully met,
deficit r/t poor and monitor :intake and assess for signs of blood transfusion done,
absorption electrolyte output, specific gravity, dehydration, assess for fluid overload, haemodynamically
balance daily weights, daily stabilized.
abdominal girth -regular vital sign helps to rule out any
measurements, deviation normal body functions as
well as presence of infection in body
-check vitals, monitor -to maintain haeomostatic equilibrium
for signs of tachycardia - to assess the proper liver function
or new murmurs, and kidney function
8. Health Family/ -Review with parents Early instruction about the My goal was met. The
Maintenance Parents the signs and complications due to altered body patient party was well
Altered ,need for familiar with symptoms of worsening function helps in early identification conscious about the
family to monitor symptoms of liver function including: and treatment if present child and no any
for symptoms of complication shows
worsening change in stool color,
increased liver up. Though,blood
liver function. ascites, peripheral
dysfunction transfusion was done.
edema,
hepato/spleenomegaly,
anorexia, urine color,
lethargy, jaundice, -early management help to gain good
bleeding, and pruritus. prognosis if any complication prevails.
-Attempt to identify of
signs and symptoms of
bleeding with treatment
of vitamin K or perhaps
even a transfusion
APPLICATION OF NURSING THEORY
By applying nursing theory of Faye Glenn Abdellah's Theory,
holistic care was given to my patient from the day of my visit.
"Nursing is based on an art and science that mould the attitudes, intellectual
competencies, and technical skills of the individual nurse into the desire and
ability to help people , sick or well, cope with their health needs." -
Abdellah
Adbellah and her colleagues thought the typology would provide a method to evaluate a
student’s experiences and also a method to evaluate a nurse’s competency based on
outcome measures.”
(Tomey & Alligood, Nursing theorists and their work 4th ed., p. 115).
Keeping these objectives in mind, I gave informal teaching and information to
patient and family.
-Nutrition: The importance of nutritious food and balanced diet. He was advised to
take plenty of fluids and soft hygienic foods.
-Infection prevention: I gave teaching on importance of personal hygiene and the role
of hygiene in infection control
CONCLUSION
Case study is one of the most important parts of nursing practice. It is the best
method of learning case study concerned with the individualized care which helps to
provide holistic nursing care including physiological, psychological, social and
cultural traditional beliefs.
According to our B.N. 1st year curriculum, I had taken a case of Jaundice,
named Shishir Kuwar for case study. During this period of case study, at first, I had
collected relevant health history from the patient as well as his family members.
Then I had done complete physical examination of my patient. I gathered lots of facts
and formulated nursing diagnosis. I applied knowledge from the basic sciences,
nursing theories and other related courses, to plan and implement nursing care. I
had studied the normal developmental task of infant and correlate it with my patient.
He meets these entire normal developmental tasks.
I had also studied about disease its type, epidemiology, etiological factors,
Pathophysiology, clinical manifestations, diagnostic test, therapeutic and nursing
management including Prognosis, Prevention and Possible Complications.
I had provided different diversion therapy to the patient for stress
management.
Finally patient’s general condition was improved day by day and I am satisfied
from this case study and the goals set were fully met.
References
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200-208
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