Neonatal cholestasis

Intrahepatic Extrahepatic

Hepatocelular Paucity of intra hepatic bile

 Biliary Atresia
 Choledochal cyst
 Syndromic-Alagille’s syndrome  Spontaneous perforation of bile ducts
 Byler’s Aagene’s  Biliary stenosis
 Non- Syndromic-α1AT deficiency  Inspissation of bile ducts
 Idiophatic familial  Mass peritoneal bands

INFECTIVE METABOLIC MICELLANEOUS IDIOPATHIC

 Galactosemia
 Her. Fructosemia
 Tyrosinaemia Hypothyroidsm
 Bacteremia
TPN
 Sepsis  α1AT deficiency
Downs
 UTI  Bile acid disorders
Shock
 TORCH infection  Fatty acid oxidation defects
Hypoperfusion
 Malaria  Cystic fibrosis]storage disorders
Congenital heart vascular
 Hepatitis B, C (nieman pick’s gauchers) etc
abnormality
 Others viral infection  Neonatal hemochromatosis
etc
 HIV  Zellweger’s
 TB