Aarnav Grover

IR I/10 GT/3rd
May 8, 2020

Meta-Cognitive Analysis Results

Year Study Method Citation Results

Sample

Study 1 2018 Maryland Air sampling using The particulate matter

State a personal aerosol Chen, R., Aherrera, was 12 times higher than
Fairground particle monitor, A., Isichei, C. et al. the outdoor environment
s in SidePak™ AM510; Assessment of
indoor air quality at while the VOC and CO2
Timonium, TSI, Shoreview,
MA, USA. MN, USA, an electronic were 2 times greater. On
electronic flow cigarette (Vaping) the other hand, NO2
calibrator (Bios convention. J Expo concentration was three
DryCal Defender; Sci Environ times less than the outside
Brandt Instruments, Epidemiol 28, 522– area. The air nicotine as
Prairieville, LA, 529 (2018).
compared to the bar or
USA, Personal https://doi.org/10.10
38/s41370-017- nightclub.
Environmental
Monitors® (PEM) 0005-x
with 37 mm PVC
filters (Both PEM
and filters from
SKC, Inc., Eighty
Four, PA) at 4 
L/min.

Study 2 2017 Six- to Randomized Drummond,

eight- clinical trial Christopher, et al. Decreased tissue
week-old “Chronic Electronic expression of miR-29b-3p
female is a mechanism of
Cigarette Vapor cardiorenal toxicity and
C57BL/6
and CD-1 Inhalation Induces organ fibrosis in chronic
(ICR) mice Renal Injury and kidney disease and in
Functional Decline response to combustible
in Female Mice.” cigarette exposure. The
The FASEB mice observed showed a
significant increase in
Journal, vol. 31, no.
renal fibrosis at the- three
1_supplement, Apr. and 6-month time points
2017, pp. 698.1- as assessed by the
698.1. trichrome standing in
these animals. the renal
 function decline by 21%
vs the control group.

Study 3 2019 86 patients Datta Collection Layden, Jennifer, et The results showed that
al., “Pulmonary those who use e-cigarettes
Illness Related to E- consistently show
Cigarette Use in respiratory and
Illinois and gastrointestinal symptoms
Wisconsin — but no upper respiratory
Preliminary symptoms, show lower
Report.” Pulmonary than normal oxygen
Illness Related to saturation, show
E-Cigarette Use in tachycardia and
Illinois and tachypnea, show
Wisconsin — leukocytosis; increase in
Preliminary Report, white blood cells, show
16 Sept. 2019. neutrophil predominance;
reaction to infection or
cancer, and show low
levels of potassium in
their blood.

Study 4 2014 The The study was Czogala, Jan, et al.

emissions conducted in an “Secondhand Nicotine concentration
of the exposure chamber Exposure to Vapors ranged from 0.82 to 6.23
Colinss, for 2 hours. At µg/m3. The concentration
From Electronic of PM2.5 was 151.7±86.8
Dekang, every hour, aersol
and Mild particles, CO, and Cigarettes.” μg/m3.
Marlboro Volatile Organic Nicotine & Tobacco
brands Compounds Research, vol. 16,
(VOCs). The no. 6, June 2014,
chamber was 39- pp. 655–62.
m3 laboratory room
(3.4×4.1×2.8
m).”The chamber
had plain acrylic
painted walls and
tiled floor, with no
windows, carpets,
linings, or curtains
 inside. It was
equipped with a
regulated exhaust,
ventilation system,
and two fans for
mixing the indoor
air. Inside the
chamber, there was
a sampling station
equipped with
pumps and
monitors, a
smoking machine
for generating e-
cigarette vapors
(see Generation of
Vapors From E-
Cigarettes section),
and two chairs. The
sampling station
was located 1 m
from a smoking
machine and 10cm
above the level of
e-cigarettes”

Study 5 2019 Conscious, Randomized “The Nicotine in E- The lack of movement

adult Clinical trial Cigarettes Appears dehydrates the mucus
female to Impair Mucus making it more sticky and
sheep Clearance.” viscous. Since the mucus
(ewes) EurekAlert!,Access is not moving out
ed 5 Nov. 2019. pathogens, it allows for
more disease to affect the
user; young users were
likely to develop chronic
bronchitis.