The document discusses questions and answers related to endocrinology, specifically about growth hormones. It defines key terms like acromegaly, panhypopituitarism, and the difference between acromegaly and gigantism. The causes, characteristics, and treatments related to excess or decreased growth hormone secretion are also summarized.
The document discusses questions and answers related to endocrinology, specifically about growth hormones. It defines key terms like acromegaly, panhypopituitarism, and the difference between acromegaly and gigantism. The causes, characteristics, and treatments related to excess or decreased growth hormone secretion are also summarized.
The document discusses questions and answers related to endocrinology, specifically about growth hormones. It defines key terms like acromegaly, panhypopituitarism, and the difference between acromegaly and gigantism. The causes, characteristics, and treatments related to excess or decreased growth hormone secretion are also summarized.
Student’s Name: Zoafshan Ashfaque Qazi D/o: Ashfaque Nabi Qazi
Class Roll No: 101 Enrollment No: JSMU/MBBS/931/SSCMS/2018
Module Name: Endocrinology
Q1: What is chemical nature of Growth Hormones?
Ans: Growth hormone is protein in nature and thus is water soluble. Q2: Where is the control tower of this hormone? Ans: The hypothalamus is the control center for the secretion of growth hormone. Q3: What is Acromegaly? Ans: Acromegaly is disease due to the excess secretion of Growth hormone in adulthood. It occurs after the epiphyses of the bones have fused. Causes: 1. Somatotrope adenoma 2. Excess secretion of GHRH from hypothalamus 3. Ectopic secretion of GHRH from non-endocrine tumors. 4. Ectopic secretion of GH by non-endocrine tumors. Characteristics: 1. Broad nose 2. Lower jaw protrusion 3. Enlarged hands and feet 4. Arthritis and carpal tunnel syndrome 5. Macroglossia (enlarged tongue) 6. Heart failure 7. Kidney failure Q4: Define Panhypopituitarism? Ans: Decreased secretion of anterior pituitary hormones, is called panhypopituitarism. It occurs due to 3 common causes: craniopharyngiomas, chromophobe tumors and thrombosis of pituitary blood vessels. Characteristics include hypothyroidism, decreased production of glucocorticoids and sex hormones. Q5: what is difference between Acromegaly and Giantism? Ans: Excess growth hormone secretion before puberty, causes gigantism whereas excess secretion in adulthood causes acromegaly. The symptoms of both conditions are remarkably similar i.e. enlarged hands and feet, protruded lower jaw, large forehead and coarse facial features. Q6: Which factor cannot be restored even treatment of Panhypopituitarism? Ans: Abnormal sexual function due to panhypopituitarism cannot be cured with any type of treatment.