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  • Biochem Immuno Reviewer

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    Carina Lunate
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    This document summarizes key differences between T cells and B cells. It notes that T cells recognize antigens via antigen presenting cells and have surface markers of CD4+ and CD8+. Their roles include clonal expansion, differentiation into effector cells, and elimination of intracellular microbes. In contrast, B cells recognize antigens via surface immunoglobulins, have their production site in the bone marrow, and differentiate into plasma cells that secrete antibodies to eliminate extracellular microbes. The document also provides an overview of the immune response process and cells of the immune system.

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    This document summarizes key differences between T cells and B cells. It notes that T cells recognize antigens via antigen presenting cells and have surface markers of CD4+ and CD8+. Their roles include clonal expansion, differentiation into effector cells, and elimination of intracellular microbes. In contrast, B cells recognize antigens via surface immunoglobulins, have their production site in the bone marrow, and differentiate into plasma cells that secrete antibodies to eliminate extracellular microbes. The document also provides an overview of the immune response process and cells of the immune system.

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    17 views1 page

    Biochem Immuno Reviewer

    Uploaded by

    Carina Lunate
    This document summarizes key differences between T cells and B cells. It notes that T cells recognize antigens via antigen presenting cells and have surface markers of CD4+ and CD8+. Their roles include clonal expansion, differentiation into effector cells, and elimination of intracellular microbes. In contrast, B cells recognize antigens via surface immunoglobulins, have their production site in the bone marrow, and differentiate into plasma cells that secrete antibodies to eliminate extracellular microbes. The document also provides an overview of the immune response process and cells of the immune system.

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    © All Rights Reserved
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    of 1

    T CELLS B CELLS

    Other name Cell mediated Humoral


    Recognize antigen by APC Surface immunoglobulins
    Production site Thymus Bone Marrow
    Surface markers (CD4+,
    Has/secretes Antibodies
    CD8+)
    Differentiate into Effector cells (CD4, CD8) Plasma cells
    Clonal expansion + +
    Memory + +
    Eliminate microbes Intracellular Extracellular

    Body’s line of defense EVENTS OF IMMUNE RESPONSE: Antigen binding to Surface immunoglobulin
    1. Tissue barriers 1. Antigen recognition 1. B cell activation
    2. Phagocytes 2. Clonal expansion 2. B cell proliferation
    3. Antibodies 3. Differentiation 3. Differentiation to plasma cell
    4. Lymphocyte activation 4. Secretion of Immunoglobulins
    Cells of the Immune System 5. Elimination of antigens (antibodies)
    A. LYMPHOCYTES 6. Apoptosis (except 5. Generation of Memory B cells
    a. B Cells
    b. T Cells MAJOR HISTOCOMPATIBILITY COMPLEX
    1. Macrophage will engulf the antigen
    c. Natural Killer CellsI
    CLASS CLASS II
    2. The parts of antigen lalabas sa surface (APC)
    B. MACROPHAGESCD8+ CD4+
    3. Will release cytokine (IL-1)
    C. OTHERS Cytolysis
    (Dendritic(kill agad)
    cells, 4. Magbind si TH cell saImmunocompetent
    presented antigencells (opsonize muna?)
    Langerhans, etc)
    5. Proliferation of TH cell (IL-2)

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