-Organic Chemistry Project-

Folk Chonthong Narkrit 1103

Index
Page 3: General information of - Paroxetine

Page 4: Chemical properties

Page 5: Physical properties

Page 6: The Applications

Page 7: General information of - Favipiravir

Page 8: Chemical properties

Page 9: Physical properties

Page 10: The Applications

Page 11: References

General Information

Paroxetine;
Antidepressant belongs to group of medicine called “selective reuptake
inhibitors” or “SSRIs”. This is mainly used to treat depression and also
balanced the chemical in the brain of people diagnosed with depression,
anxiety or other disorders.

SSRI
class of drugs that are typically used as
antidepressants in the treatment of major
depressive disorder and anxiety
disorders.
 Chemical Properties

Molecular Weight 329.4 g/mol Heavy Atom Count 24

Hydrogen Bond 1 Formal Charge 0

Donor Count

Hydrogen Bond 5 Complexity 402

Acceptor Count

Rotatable Bond 4 Isotope Atom Count 0

Count

Exact Mass 329.142722 g/mol Monoisotopic Mass 329.142722 g/mol

 Physical Properties

Solid

Boiling point - 451.7±45.0

Melting point - 129-131°C

Solubility - 5.4 mg/mL

Application

Functional group in paroxetine can be apply to many things such as:

Oxalic Acid - Paint remover

Maleic Acid - making polyesters for fibre-reinforced

Fumaric Acid - Making Wheat

l-Tartaric acid - acidulant in grape and favored beverage.

General Information
Antiviral medicine - medication
used for treating viral infections.

Favipiravir;
A chemical also known as T-705, the use of which is applied to patients who contain
the RNA virus, that is, it is an antiviral medicine.
 Chemical Properties

Molecular Weight 157.1 g/mol Heavy Atom Count 11

Hydrogen Bond 2 Formal Charge 0

Donor Count

Hydrogen Bond 4 Complexity 282

Acceptor Count

Rotatable Bond 1 Isotope Atom Count 0

Count

Exact Mass 157.028755 g/mol Monoisotopic Mass 157.028755 g/mol

Physical Properties

Melting Point - 187℃ to 193℃

Solubility - slightly soluble in water

Application
Compound in Favipiravir can be apply to many things such as:

Guanosine - protective role in response to degenerative diseases or injury.

Inosine - improving athletic performance.

AICAR - used in the 1980s to preserve blood flow to the heart during surgery
References

AICAR, AMPK's Activator: Basic Information and Popular Uses: AG Scientific Blog. (n.d.). Retrieved from
https://agscientific.com/blog/2014/01/aicar-ampks-activator-basic-information-and-popular-uses/

English, A. S. (2020, April 8). What is Favipiravir, the drug used in China to fight Covid-19? Retrieved from
https://en.as.com/en/2020/04/08/other_sports/1586359058_132520.html

Paroxetine. (n.d.). Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Paroxetine

Tartaric Acid. (n.d.). Retrieved from https://www.sciencedirect.com/topics/medicine-and-dentistry/tartaric-acid

Inosine: Uses, Side Effects, Interactions, Dosage, and Warning. (n.d.). Retrieved from
https://www.webmd.com/vitamins/ai/ingredientmono-704/inosine

Lanznaster, D., Dal-Cim, T., Piermartiri, T. C. B., & Tasca, C. I. (2016, October 1). Guanosine: a Neuromodulator with
Therapeutic Potential in Brain Disorders. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036959/

Shiraki, K., & Daikoku, T. (2020, February 22). Favipiravir, an anti-influenza drug against life-threatening RNA virus infections.
Retrieved from https://www.sciencedirect.com/science/article/pii/S0163725820300401

Paroxetine Uses, Dosage & Side Effects. (n.d.). Retrieved from https://www.drugs.com/paroxetine.html