1.

Clinical Assessment a) CD4+T cell count and viral load

2. Goals of ART
a) NRTIs & NNRTIs
b) PIs
3. Classes of ARVs & their mechanisms of action
c) in STIs
d) Entry inhibitors
4. Antiretroviral drugs available in southern Africa
Chapter 6: Antiretroviral therapy

5. Guidelines for the use of ART a) When to start ARTs

b) Counselling before ART initiation
c) Choice of drug regime
d) Use of ART in patients with TB
e) Drug Interactions
6. Adverse effect of ART

7. How to know if ART is effective

a) IRIS
8. When to change ART

9. Development of drug-resistant viruses

a) Non-adherence and drug resistance
10. Adherence to ART

11. Prevention of mother-to-child transmission a) Reasons for non-adherence

b) Strategies for improving adherence to ART

12. Post-exposure prophylaxis after occupational

exposure
a) Infant prophylaxis
13. PEP after rape or sexual assault

14. Pre-exposure prophylaxis