Primary/benig Myxoma Papillary fibroelastoma Fibroma Lipoma Rhabdomyoma

n cardiac
tumor
Most common Fossa ovalis in the atrial Adults: frequently on the aortic Septal most often left or the right side
septum valve, children: tricuspid valve. myocardiu located in the of the heart and
site of tumor
Most common valvular tumor. m. left ventricle, protruding into the
Often right atrium, or ventricular
encroach atrial septum. chambers.
on the It can affect
conduction myocardium,
system as pericardium,
they grow subendocardim,
subepicardium.
Age >35 >60 < 30
Infants and children.
Single/maltiple Single Encapsulat Poorly
ed, Solitary encapsulated.
tumors
(single/alon
e)
Gross - Sessile or pedinculated. - Small tumors (<1cm) with - Small, gray‐white
- Typically pedunculated. homogeneous speckled pattern. myocardial masses.
appearance
- Range from ≤1 cm‐10
cm). - Commonly pedunculated with - Located on either
- Gelatinous consistency. multiple fronds. the left or the right
- Friable. side of the heart
- Affect the Lt and Rt sides with and protruding into
same frequency Attach to: the ventricular
1. Atrial surface of AV valves chambers.
2. Ventricular surface of
semilunar valves
Histology - Copious Covered by endothelium, deep Mixed population of
mucopolysaccharide to which is myxoid connective cells, the most
stroma. tissue containing abundant characteristic of
mucopolysaccharide matrix and which are large,
- Scattered solitary or elastic fibers. rounded, or
clustered stellate or polygonal cells
polygonal cells. Fibroelastomas resemble Lambl containing
excrescences. numerous glycogen‐
laden vacuoles
- Covered on the surface
separated by
by endothelial cells.
strands of
cytoplasm running
- Structures that variably
resemble poorly formed from the plasma
membrane to the
glands or vessels are
more or less
characteristic.
centrally located
nucleus, the so‐
- Hemorrhage and
called spider cells.
mononuclear
These cells can be
inflammation are usually
shown to have
present.
myofibrils.

Clinical - Valvular "ball‐valve" - Symptomatic only in the aortic - V.Fib is -Asymptomatic. - Obstruction of a
obstruction. position (other than embolic Sx) often the - Valvular "ball‐ valvular orifice or
Manifestations
- Embolization. - Ostial occlusion > angina, first. valve" cardiac chamber.
- Syndrome of sudden death. obstruction.
constitutional symptoms. - Rarely valvular dysfunctionon Presentation. - Associated with
- Source of embolization in up to - Arrhythmias. tuberous sclerosis
30% of patients - In the atrial
septum: non‐
neoplastic
depositions of
fat (lipomatous
hypertrophy).
Extra-cardiac - Fever
- ESR elevation
Manifestations
- Anemia
- Thrombocythemia
- Circulating
autoantibodies