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    Gentamicin is an antibiotic used to treat gram-negative infections. It works by disrupting the ribosome's ability to proofread mRNA during protein synthesis. Common side effects include hearing loss, dizziness, and kidney problems. Nurses monitor for these side effects and assess renal function through tests like BUN and creatinine. They also check the infection site and educate patients on reporting serious adverse reactions.

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    Gentamicin is an antibiotic used to treat gram-negative infections. It works by disrupting the ribosome's ability to proofread mRNA during protein synthesis. Common side effects include hearing loss, dizziness, and kidney problems. Nurses monitor for these side effects and assess renal function through tests like BUN and creatinine. They also check the infection site and educate patients on reporting serious adverse reactions.

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    3K views3 pages

    Drugs Study Gentamicin

    Uploaded by

    ahmad ryan
    Gentamicin is an antibiotic used to treat gram-negative infections. It works by disrupting the ribosome's ability to proofread mRNA during protein synthesis. Common side effects include hearing loss, dizziness, and kidney problems. Nurses monitor for these side effects and assess renal function through tests like BUN and creatinine. They also check the infection site and educate patients on reporting serious adverse reactions.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    of 3

    GENERIC NAME: DOSAGE/ SIDE EFFECTS/ NURSING

    Gentamicin FREQUENCY/ ROUTE: ADVERSE REACTION RESPONSIBILITIES


    3mg/kg/day q 8 hours

    BRAND NAME: INDICATION:  hearing loss, or a Assessment


    Garamycin  Gram Negative roaring sound in your
    Cidomycin infections ears;  History: Allergy to
     severe or any
    DRUG ILLUSTRATION: ongoing dizziness; aminoglycosides;
     weak or shallow renal or hepatic
    breathing; disease; preexisting
     numbness or tingly hearing loss; active
    feeling; infection with
     twitching, muscle herpes, vaccinia,
    tightness or varicella, fungal
    contraction; infections,
    CLASSIFICATION: CONTRAINDICATION:  seizure (convulsions); myobacterial
    Antibiotic  severe stomach pain, infections
     Neurotoxicity diarrhea that is watery (ophthalmic
     Aminoglycosides or bloody; preparations);
    MECHANISM OF  Neuromuscular  fever, blisters or ulcers myasthenia gravis;
    ACTION: Blockade in your mouth, red or parkinsonism; infant
    The primary mechanism of  Respiratory paralysis swollen gums, trouble botulism; lactation,
    action is generally accepted swallowing; pregnancy
    to work through ablating the  kidney problems--little  Physical: Site of
    ability of the ribosome to or no urinating; painful infection; skin color,
    discriminate on or difficult urination; lesions; orientation,
    proper transfer swelling in your feet or reflexes, eighth
    RNA and messenger ankles; feeling tired or cranial nerve
    RNA interactions.Typically, short of breath; function; P, BP; R,
    if an incorrect tRNA pairs  signs of an electrolyte adventitious sounds;
    with an mRNA codon at imbalance--confusion, bowel sounds, liver
    the aminoacyl site of the weakness, bone pain, evaluation;
    ribosome, adenosines 1492 increased urination; or urinalysis, BUN,
    and 1493 are excluded from  increased pressure serum creatinine,
    the interaction and retract, inside the skull--severe serum electrolytes,
    signaling the ribosome to headaches, ringing in LFTs, CBC
    reject the aminoacylated your ears,  Avoid long-term
    tRNA::Elongation Factor dizziness, nausea, therapies because of
    Thermo-Unstable complex. vision problems, pain increased risk of
    behind your eyes. toxicities. Reduction
    in dose may be
    Side effects may be more clinically indicated.
    likely in older adults.  Patients with edema
    or ascites may have
    lower peak
    Common side effects may concentrations due
    include: to expanded
    extracellular fluid
     vision problems; volume.
     nausea, vomiting,  You may experience
    loss of these side effects:
    appetite, weight Ringing in the ears,
    loss; headache, dizziness
     a light-headed (reversible; use
    feeling, like you safety measures if
    might pass out; severe); nausea,
     itching or rash; vomiting, loss of
     pain where the appetite (eat
    medicine was frequent small
    injected; meals, perform
     headache, mood frequent mouth
    changes; or care); burning,
     joint pain. blurring of vision
    with ophthalmic
    preparations (avoid
    driving or
    performing
    dangerous activities
    if visual effects
    occur);
    photosensitization
    with dermatologic
    preparations (wear
    sunscreen and
    protective clothing).
     Report pain at
    injection site, severe
    headache, dizziness,
    loss of hearing,
    changes in urine
    pattern, difficulty
    breathing, rash or
    skin lesions; itching
    or irritation
    (ophthalmic
    preparations);
    worsening of the
    condition, rash,
    irritation
    (dermatologic
    preparation).

    REFERENCES

    https://www.drugs.com/mtm/gentamicin.html

    https://www.rxwiki.com/gentamicin

    https://en.wikipedia.org/wiki/Gentamicin#Mechanism_of_action

    https://www.webmd.com/drugs/2/drug-1496/gentamicin-injection/details

    https://www.rxlist.com/consumer_gentamicin/drugs-condition.htm

    https://www.pediatriconcall.com/drugs/gentamicin/612

    https://www.rnpedia.com/nursing-notes/pharmacology-drug-study-notes/gentamicin-sulfate/

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