Stephanie Preston

Drug​: Measles, Mumps, and Rubella Virus Vaccine Live [MMR II]
Indication for Use: ​Recommended Vaccine to receive first at 12 months of age and then again at 4-6 years.
Mechanism of Action: ​Introduces small amounts of the virus and trains the immune system to recognize
and combat the pathogen.

Form Dose Route of Administration instructions Treatment notes

Administration

Single dose 0.5 Subcutaneous First withdraw the entire volume Secretion into breastmilk
vial of ml Injection of diluent into the syringe to be after administration of the
vaccine and preferably in the used for reconstitution. Inject all vaccine is unknown.
single dose upper outer arm the diluent in the syringe into the Potential that some of the
vial of diluent vial of lyophilized vaccine, and vaccine may be passed to
to be mixed agitate to mix thoroughly. If the the infant.
lyophilized vaccine cannot be
dissolved, discard. Withdraw the
entire contents into a syringe,
inject the total volume of restored
vaccine subcutaneously, and
discard vial.

Contraindications:
● Hypersensitivity to any component of the vaccine, including gelatin.
● Pregnancy and pregnancy should be avoided for 3 months following vaccination
● Anaphylactic reactions to neomycin
● Febrile respiratory illness or other active febrile infection
● Patients receiving immunosuppressive therapy
● Individuals with blood dyscrasias, leukemia, lymphomas or any type or other malignant neoplasms
affecting bone marrow or lymphatic systems.
● Primary and acquired immunodeficiency states.
● Individuals with a family history of congenital or hereditary immunodeficiency until the immune
competence of the recipient is demonstrated.

Storage: ​To maintain potency, it must be stored between -58°F and +46°F (-50°C to +8°C). Protect the
vaccine from light at all times, since such exposure may inactivate the viruses. Before reconstitution, store
the lyophilized vaccine at 36°F to 46°F (2°C to 8°C). The diluent may be stored in the refrigerator with the
lyophilized vaccine or separately at room temperature. Do not freeze the diluent. It is recommended that the
vaccine be used as soon as possible after reconstitution. Store reconstituted vaccine in the vaccine vial in a
dark place at 36°F to 46°F (2°C to 8°C) and discard if not used within 8 hours.
Stephanie Preston

Resources -
MMR II package Insert -
https://www.merck.com/product/usa/pi_circulars/m/mmr_ii/mmr_ii_pi.pdf