TAGUM DOCTORS COLLEGE INC.

Mahogany St., Rabe Subdivision Tagum City

Bachelor of Science in Nursing

DRUG STUDY
Name of Student : Sian, Liza P. – BSN3, Group 1
Name of Client : Joanna, Jacob Age: 4 y.o. Sex: Female Rating:
Date of assessment: March 04, 2019 Physician: Status:
Chief complaint : Admitting diagnosis:
Benign Convulsion

Date Image of Drug Name of Classification Dosage/ Mechanism of Action

Drug Time/Route
March 04, Brand Cephalosporins 750mg, Cefuroxime inhibits bacterial cell wall synthesis by binding to
2019 name: IVTT, one 1 or more of the penicillin-binding proteins (PBPs) which in
8ml, every 8 turn inhibit the final transpeptidation step of peptidoglycan
Generic hours, TID synthesis in bacterial cell walls, thus inhibiting cell wall
name: biosynthesis and arresting cell wall assembly resulting in
Cefuroxime bacterial cell death.
Pharmacokinetics:
Absorption: Absorbed from the GI tract with peak plasma
concentrations after 2-3 hr (oral); may be enhanced by the
presence of food.
Distribution: Pleural and synovial fluid, sputum, bone and
aqueous fluids; CSF (therapeutic concentrations). Crosses the
placenta and enters breast milk. Protein-binding: Up to 50%.
Metabolism: Rapidly hydrolysed (intestinal mucosa and
blood).
Excretion: Via the urine by glomerular filtration and renal
tubular secretion (as unchanged); via bile (small amounts); 70
min (elimination half-life); prolonged in neonates and renal
impairment.
 Indication Contraindications Adverse Reaction Nursing Responsibilities
Acute streptococcal tonsillitis Severe GI upset, headache, 1. Before initiating therapy, obtain a history to determine
and pharyngitis, acute bacterial hypersensitivity to dizziness, eosinophilia, previous use of and reactions to penicillins or cephalosporins.
sinusitis, acute otitis media, other β-lactams. neutropenia, decreased Persons with a negative history of penicillin sensitivity may
acute exacerbations of chronic haemoglobin, transient still have an allergic response.
bronchitis, cystitis, increases in liver enzymes, 2. Assess patient for signs and symptoms of infection prior to
pyelonephritis, uncomplicated candida overgrowth, inj site and throughout therapy.
SSTI, early Lyme disease. reactions. Reports of 3. May experience these side effects: Stomach upset or diarrhea.
pseudomembranous colitis, 4. Observe patient for signs and symptoms of anaphylaxis (rash,
positive Coombs test, pruritus, laryngeal edema, wheezing). Discontinue the drug
haemolytic anaemia. and notify physician or other health care professional
immediately if these symptoms occur. Keep
thromepinephrine, an antihistamine, and resuscitation
equipment close by in the event of an anaphylactic reaction.
5. Culture infection, and arrange for sensitivity tests before and
during therapy if expected response is not seen.
6. Instruct patient to report signs of hypersensitivity.
7. Discontinue if hypersensitivity reaction occurs.

Reference: www.drugs.com
 TAGUM DOCTORS COLLEGE INC.
Mahogany St., Rabe Subdivision Tagum City
Bachelor of Science in Nursing

DRUG STUDY
Name of Student : Sian, Liza P. – BSN3, Group 1
Name of Client : Lara, Sean Age: 3 y.o. Sex: Male Rating:
Date of assessment: March 06, 2019 Physician: Status:
Chief complaint : Admitting diagnosis: t/c AGE

Date Image of Drug Name of Classification Dosage/ Mechanism of Action

Drug Time/Route
March 06, Brand Antiemetics / GIT 10mg, PO, Domperidone is a peripheral dopamine-receptor blocker. It
2019 name: Regulators, every 8 hours, increases oesophageal peristalsis, enhances gastroduodenal
Antiflatulents & TID coordination and lower oesophageal sphincter pressure, gastric
Generic Anti- motility, and peristalsis, thus facilitating gastric emptying and
name: Inflammatories decreasing small bowel transit time.
Domperidone Pharmacokinetics:
Absorption: Rapidly absorbed. Food may delay absorption.
Bioavailability: Approx 15% (oral and rectal). Time to peak
plasma concentration: Approx 30 min (oral); approx 1 hr
(rectal).
Distribution: Enters breast milk (small amounts). Plasma
protein binding: >90%.
Metabolism: Undergoes rapid and extensive hepatic
metabolism
Excretion: Via urine (approx 30%, mainly as metabolites);
faeces (approx 66%, 10% as unchanged drug). Elimination half-
life: Approx 7.5 hr.
 Indication Contraindications Adverse Reaction Nursing Responsibilities
Nausea and vomiting; GI Known CNS: headache, insomnia 1. Monitor for persistence of nausea and vomiting to evaluate the
motility disorder hypersensitivity/intole effectiveness of the drug.
rance; GI: dry mouth 2. Monitor for signs of abdominal discomfort such as epigastric
Concurrent use of pain or abdominal fullness.
ketoconazole; GU: amenorrhea, impotence 3.Monitor vital signs to determine signs of dehydration.
Prolactinoma; 4.Perform oral care.
Conditions where GI Derm: hot flushes, rash 5.Do not increase dose or take this more.
stimulation is 6.Tell patient that she/he may get dizzy or drowsy with this
dangerous including Endo: galactorrhea, drug, tell not to sit or stand quickly.
GI hemorrhage/ gynecomastia, 7. Monitor BP (sitting, standing, lying down) and pulse before
mechanical hyperprolactinemia and periodically during therapy.
obstruction/ 8. Monitor for symptoms related to hyperprolactinemia
perforation; (menstrual abnormalities, galactorrhea, sexual dysfunction).
Lactation:Breast 9. Instruct patient to take as directed. Advise patient to avoid
feeding is not grapefruit juice during therapy.
recommended unless 10. Advise patient to notify health care professional if
potential benefits palpitations, irregular heart beat (arrhythmia), dizziness, or
outweigh potential fainting occur.
risks.

Reference: www.drugs.com