Linezolid is an expensive antibiotic available as injections, tablets, or oral suspension that is reserved for multidrug-resistant infections. It is used in hospitals due to risks of bone marrow suppression, peripheral neuropathy with long-term use, and increased blood pressure when combined with certain drugs. Linezolid inhibits bacterial protein synthesis and is effective against gram-positive bacteria like methicillin-resistant Staphylococcus aureus.
Linezolid is an expensive antibiotic available as injections, tablets, or oral suspension that is reserved for multidrug-resistant infections. It is used in hospitals due to risks of bone marrow suppression, peripheral neuropathy with long-term use, and increased blood pressure when combined with certain drugs. Linezolid inhibits bacterial protein synthesis and is effective against gram-positive bacteria like methicillin-resistant Staphylococcus aureus.
Linezolid is an expensive antibiotic available as injections, tablets, or oral suspension that is reserved for multidrug-resistant infections. It is used in hospitals due to risks of bone marrow suppression, peripheral neuropathy with long-term use, and increased blood pressure when combined with certain drugs. Linezolid inhibits bacterial protein synthesis and is effective against gram-positive bacteria like methicillin-resistant Staphylococcus aureus.
Linezolid is an expensive antibiotic available as injections, tablets, or oral suspension that is reserved for multidrug-resistant infections. It is used in hospitals due to risks of bone marrow suppression, peripheral neuropathy with long-term use, and increased blood pressure when combined with certain drugs. Linezolid inhibits bacterial protein synthesis and is effective against gram-positive bacteria like methicillin-resistant Staphylococcus aureus.
- It is available in the form of injections, tablets and an oral suspension.
(All are expensive.)
- Bone marrow suppression and peripheral neuropathy are sometimes observed general - Therapy with linezolid is reserved for multidrug-resistant infections and should with prolonged therapy (more than 14 days) and regular haematological and be commenced in hospital. neurological monitoring are recommended. - Due to its monoamine oxidase inhibitory activity, blood pressure can increase adverse mechanism when linezolid is used in combination with dopamine, adrenaline, serotonergic - Linezolid inhibits an early step in bacterial protein synthesis. drugs (eg selective serotonin reuptake inhibitors, monoamine oxidase inhibitors, effects linezolid of action tramadol, pethidine), pseudoephedrine, and foods with a high tyramine content. - There have been reports of serotonin syndrome and coadministration with serotonergic drugs should be avoided. - It is effective against Gram-positive organisms, including methicillin-resistant spectrum strains of Staphylococcus aureus, coagulase-negative staphylococci, VRE, of action and penicillin-resistant strains of Streptococcus pneumoniae.