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Filter Types For The Pharmaceutical Industry - Water Tech Online
Filter Types For The Pharmaceutical Industry - Water Tech Online
Filter Types For The Pharmaceutical Industry - Water Tech Online
There are various filtration systems that are commonly used within the pharmaceutical industry.
Meant to help purify a medium, filters are used in a number of different industries to
capture and contain contaminants and other debris while allowing the desired liquid to pass
through. Within the pharmaceutical industry, membrane filters are commonly used to help
sterilize and deionize water that will later be used within the industry. When it comes to
choosing the right filter for a system, there are a number of factors to consider.
Filtration Systems
Within the pharmaceutical industry, there are various filtration systems that are commonly
used. Surface filtration, depth filtration, and ultrafiltration are all systems that are used
within the industry for different purposes, and each filter system comes with a number of
advantages when used. The following provides some key information about each filter
system type.
Surface Filtration
Surface filtration systems are designed for the purpose of retaining particles on the surface
of the matter being filtered. These particles build up over time as filtration continues and
form a solid layer of material on the surface level. This layer, often referred to as a “cake
layer,” helps increase the filter’s efficiency as it forms. While the initial rate of filtration
when using surface filters is only around 55 percent, once a cake layer has formed, the rate
of filtration increases to 100 percent. Within the surface filtration process, a reduction in
flow will eventually occur as matter continues to build up within the system, requiring
occasional maintenance. The system will need to be stopped to allow for the filter to be
cleaned.
Depth Filtration
Within the depth filtration system, material flows down a long pathway through a number
of different filter layers before exiting the filter system. This filtration process is used to
remove particles, soluble materials, and colloidal materials from fluid. At the beginning of
the pathway, larger particles are first removed. Then, as the material flows through the
depth filter, smaller and smaller particles are filtered out.
Depth filtration systems are cleaned using backflow, reversing the flow of the medium and
thus unclogging the pores in the filter. Compared to surface filtration, depth filter systems
are more expensive. However, they are able to be used for a longer period of time than
surface filter systems.
Ultrafiltration
Filter Types
When it comes to choosing a filter type, there are a number of different things that should
be considered. With those used within the pharmaceutical industry, there are a few different
filters to choose from. Different filter types come with different advantages and
disadvantages, so understanding the filter types and how they work is important before
choosing a filter.
Magnetic Filters
Commonly used within liquid pharmaceutical production systems, magnetic filters are
useful when purity within the medium is required. Magnetic filters are most frequently used
to remove iron particles from liquid media. When magnetic filters become full to their
capacity, they can be removed, cleaned, and reused.
Bag Filters
Bag filters are low-cost filters that use a method of microfiltration in order to remove
contaminants from liquid material. The medium flows through small pores within the filter
itself, while any debris are caught inside the bag, eventually filling it up. Pore size, when it
comes to bag filters, can vary greatly, so it is important to know what filter size is required.
Within smaller systems, bag filtration can be incredibly efficient, as bags will not fill as
rapidly with contaminants, lowering replacement bag costs.
Self-Cleaning Filters
For high-demand, large-scale filtration systems, self-cleaning filters are often chosen. The
biggest advantage that comes with using self-cleaning filters is their ability to perform their
own maintenance. When using other types of filters, the pipeline or system as a whole must
be shut down periodically for maintenance. Self-cleaning filters commonly use backwashing
to push debris away from the sides of the filter and toward the bottom of the filter’s housing.
From there, the debris are pushed all the way out of the system while the filter remains in
place.
Filter Membranes
Filter membranes are another aspect of a filtration system that will need to be chosen. The
most common filter membrane types are reverse osmosis, ultrafiltration, and nanofiltration.
Within the pharmaceutical industry, membranes are used to sterilize and deionize water.
Different membranes should be used in different systems depending on their
characteristics.
Reverse Osmosis
Commonly used for the process of refining antibiotics and concentration of hormones
within the pharmaceutical industry, reverse osmosis filters typically come with pore sizes
around 0.0001 micron. Once water is passed through a reverse osmosis filter, it becomes
pure water. Reverse osmosis is able to remove viruses, organic molecules, and even most
minerals from water. The water being passed through the filter is also desalinated, as
reverse osmosis also removes monovalent ions within the water.
Ultrafiltration
Nanofiltration
With a pore size of approximately 0.001 micron, nanofiltration is commonly used to remove
a number of contaminants from water, including organic molecules, almost all viruses, any
organic matter, and a number of different salts. Nanofiltration is commonly used to soften
hard water. This is because nanofiltration is able to remove divalent ions within the water,
which cause hard water in the first place.
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