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Competitive Exams: Pharmacy MCQs (Practice_Test 8 of 29)

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1. Effects seen only with depolarizing blockade include all of the following EXCEPT:

a. Hyperkalemia

b. A decrease in intraocular pressure

c. Emesis

d. Muscle pain

2. Correct statements about cortisol (hydrocortisone) include all of the following, EXCEPT:

a. Cortisol is synthesized from cholesterol

b. ACTH governs cortisol secretion

c. Most cortisol is inactivated in the liver

d. The half-life of cortisol in the circulations is normally about 60 − 90 hours

3. Which neuromuscular blocking agent is contraindicated in patients with glaucoma?

a. Tubocurarine

b. Succinylcholine

c. Pancuronium

d. Gallamine

4. Which of the following glucocorticoids is a short-to medium-acting drug?

a. Prednisolon

b. Dexamethasone

c. Triamcinolone

d. All of the above

5. Which of the following diseases can augment the neuromuscular blockade produced by
nondepolarizing musclerelaxants?

a. Myasthenia gravis

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b. Burns

c. Asthma

d. Parkinsonism

6. the drug which belongs to nucleoside reverse transcriptase inhibitors:

a. Didanosine

b. Gancyclovir

c. Nevirapine

d. Vidarabine

7. The unwanted effects of zidovudine:

a. Hallucinations, dizziness

b. Anemia, neutropenia, nausea, insomnia

c. Hypertension, vomiting

d. Peripheral neuropathy

8. Indicate the agent, which effectively antagonizes the neuromuscular blockade caused by
nondepolarizing drugs:

a. Atropine

b. Neostigmine

c. Acetylcholine

d. Pralidoxime

9. Which of the following sympathomimetics acts indirectly?

a. Epinephrine

b. Norepinephrine

c. Ephedrine

d. Methoxamine

10. Which of the following statements is not correct?

a. ALFA receptors increase arterial resistence, whereas beta receptor promote smooth
muscle relaxation

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b. The skin and splanchic vessels have predominantly alfa receptors

c. Vessels in a skeletal muscle may constrict or dilate depending on whether alfa or

beta receptors are activated

d. Skeletal muscle vessels hav predominantly alfa receptors and constrict in the
presence of epinephrine and norepinephrine

11. the group of hormonal drugs used for cancer treatment:

a. Mineralocorticoids and glucocorticoids

b. Glucocorticoids and gonadal hormones

c. Gonadal hormones and somatotropin

d. Insulin

12. Methotrexate is:

a. A purine antagonist

b. A folic acid antagonist

c. An antibiotic

d. An alkylating agent

13. The action mechanism of anticancer drugs belonging to plant alkaloids:

a. Inhibition of DNA-dependent RNA synthesis

b. Cross-linking of DNA

c. Mitotic arrest at a metaphase

d. Nonselective inhibition of aromatases

14. Serious side effects of glucocorticoids include the following, EXCEPT:

a. Acute peptic ulcers

b. Iatrogenic Cushing's syndrome

c. Salicylism

d. Hypomania or acute psychosis

15. Side effect of cyclosporine A is:

a. Tremor

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b. Anorexia

c. Chills

d. Myalgia

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