NSN le ett res NRC en en nh Mere ContonkGekion, ae Lert leer lect eon es frets fteecb ier lee Cote Fh AH pet Pyerrerchy- mi vemneodh int Bete itienb ia 425 fuse fo Shim Grea a» Gecreyienh Laigiown- Eee fer Core fla phe Storr hives of = =o = ete thet td Voi Por i?S + oO & Rrecdl) qasflelibion Coe $fieien 22 — —_ Ag rea, Srne GAMNAK 0 F dare ttherk taloloudls eter fre plete ns Co — 1S forsee incknchion oviel fp pee eg —€ obs f laren} — ete he a netics apie oft GABK- Lele fort $ Vo. neveabubitis SenSniihese— Tefen ae tater Sega sed eS 5 Ahenat pte —< es Ce fucderep-mf Pec tedl-on Ah he 4 te te oSeclidie lines ~~ ~“= Anesthetic MAC (%) | Blood:Gas Coefficient @ 37°C .4 Oxide ei 2.3 otioneFactors affect MAC Decreasing MAC Uitee coy Ades - Increasing age “ > Pregnancy + Hypothermia - ~ Hypothyroidism : - Hyponatraemia - - Hyporension - ~ Hypoxia +. Metabolic acidosis + Acute alcohol - Narcotics - Ketamine - Benzodiazepines - a2 agonists + Lithium Young age (infants and children) Hyperthermia Hypernatraeia Chronic alcohol use Increased sympathoadrena stimulation (MAO inhibitors, acute amphetamines, ephedrine, cocaine) ~~, Duration of anaesthesia Sex Alkalosis Hypertension Anaemia Magnesium and potassium level