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Alugbati Stuart
Alugbati Stuart
Family • Basellaceae
Alugbati
Basella alba Linn.
SPINACH VINE
Yan zhi cai
Distribution
- Found in settled areas, in hedges, old cultivated areas, etc., throughout the Philippines.
- Often cultivated.
- Prehistoric introduction.
- Also occurs in tropical Asia, Africa, and Malaya.
Constituents
• Phytochemical screening of various extracts yielded cardiac glycosides, saponins, tannins, flavonoids,
terpenoids, carbohydrates, and reducing sugars.
• Study isolated Basellasaponins A, B, C, and D, oleanane-type triterpenes oligoglycosides, together
with betavulgaroside 1, spinacoside C, and momordins IIb and IIc, from fresh aerial parts.
• Leaves yield saponin, vitamin A and B.
• Fruit yields mucilage and iron.
• Study of wild Basella rubra showed it to be abundant in carotene, middle in vitamin C, and low in
nitrate. Nitrate in planted B. rubra is about twice that of the wild variety.
Properties
• Aperient, demulcent, diuretic, emollient, laxative,
rubefacient.
• Mucilaginous when cooked.
• Studies exhibited androgenic, antidiabetic, anti-
inflammatory, antimicrobial, antioxidant, antiulcer,
antiviral, CNS depressant, hepatoprotective, and
wound healing activities.
Uses
Edibility / Nutrition
- Common market product, a popular leafy and stew
vegetable, and a good substitute for spinach.
- The green and purple cultivated varieties are
preferable to the wild ones.
- Both the young shoots and stems are eaten.
- Excellent source of calcium and iron; good source
of vitamins A, B, and C, with a high roughage value.
Folkloric
- Roots are employed as rubefacient.
- Poultice of leaves used to reduce local swelling.
- Sap is applied to acne eruptions to reduce
inflammation.
- Decoction of leaves used for its mild laxative
effects.
- Pulped leaves applied to boils and ulcers to hasten
suppuration.
- Sugared juice of leaves useful for catarrhal
afflictions in children.
- Leaf-juice, mixed with butter, is soothing and
cooling when applied to burns and scalds.
- In India, used in hemorrhagic diseases and as
tonic. Also used for burns and pruritic skin lesions. In Orissa, India, paste of root in rice water taken in
the morning on an empty stomach for a month to cure irregular periods.
- In Nigeria, leaves used for hypertension. In Cameroonian folk medicine, used for malaria.
- Mucilaginous liquid obtained from the leaves and tender stalks used for habitual headaches.
- In Ayurveda, used for hemorrhages, skin diseases, sexual weakness, ulcers and as laxative in
children. Leaves applied on the head for half a hour before bathing to help bring about a good refreshing
sleep. Sap is applied to acne eruptions to reduce inflammation. Decoction of leaves used for a mild
laxative effect. Pulped leaves applied to boils and ulcers to hasten suppuration. Leaf juice mixed with
butter applied to burns and scalds for a soothing and cooling effect. Leaves and stems have been used
as anticancer for melanoma, leukemia, and oral cancer.
- Roots and leaves used for the removal of after birth, stomach pains, and increase milk production.
- Used orally for anal prolapse and hernia.
- In Nigeria, used for hypertension. (37) Also used for fertility enhancement in women.
- In Nepal, leaf juice is used to treat dysentery, catarrh, and applied externally to boils.
- In Thai traditional medicine, the mucilage is used as application for bruises, ringworm, and laboring.
Stem and leaves used as mild laxative, diuretic and antipyretic.
- In Cameroon used for malaria. (37) Herbal healers use plant extracts to enhance libido and as remedy
for infertility.
- In Antilles leaves considered good maturative as cataplasm.
- In Thai traditional medicine, mucilage is used as topical medicine for skin irritation, bruises, ringworm,
and laboring. (37)
Others
Cosmetic: Fruit used by women as rouge for cheeks and lips; also as a dye.
Dye: With the anthocyanin content, it makes for a natural food colorant. Fruit provides a dark violet color
as food colorant.
Veterinary: Ground leaves rubbed on the human hand to introduce the preparation into the animal
vagina every morning for the treatment of sterility.
Pharmaceuticals: Plant mucilage has been proposed for applications in medicine and cosmetics. The
mucilage has also been proposed as thickener, water-retention agent, gelling agent, suspending agent
and film former.
Studies
• Anthocyanins / Natural Food Colorant : Study of pigment extracted from fruits of spinach vine (B.
rubra) showed good stability with a potential as a natural food color. (1)
• Antifungal: Study yielded two antifungal peptides with potent activity against Botrytis cinerea,
Mycosphaerella arachidicola and Fusarium oxysporum. (4)
• Antimicrobial / Leaves: A study of the aqueous, ethanolic and petroleum ether extracts of the leaves
of Basella rubra exhibited antimicrobial activity against all test organisms except P aeruginosa. The
ethanolic extract showed maximum effect against E coli. Further studies are needed to isolate the active
compound responsible for the antimicrobial effect. (6)
• Hypoglycemic / Leaf Pulp: A study of STZ-induced diabetic rats fed with Basella rubra showed the
leaf pulp of B. rubra possesses a strong hypoglycemic effect. (7)
• Volatile Flavor Components: Study identified volatile flavor components. The major components from
the volatile oil were: 1-methoxypropane, (Z)-3-hexen-l-ol, 3-methoxyphenyl acetate, acetophenone, 4-
vinylguaiacol, isophytol, and phytol. (8)
• Dyestuff / Microbiological Stain: Study showed the anthocyanin extracted from Basella rubra berries
produced a stain comparable with synthetic stains like crystal violet and safranin, and can be used as an
alternative microbiological stain. (9)
• Antidiabetic / Antioxidant: Study evaluated the action of B. rubra against streptozotocin-induced
diabetes in rats. Results showed effective reduction of oxidative stress induced by streptozotocin and
potential reduction in blood sugar level. (12)
• Antihyperglycemic / Antioxidant: Study evaluated an aqueous extract of B. rubra for
antihyperglycemic activity in STZ-induced diabetic rats. Phytochemical screening showed a rich source
of phytonutrients, including enzymic and nonenzymic antioxidants. Results concluded the aqueous
extract exhibited significant antihyperglycemic activity. (14)
• Haematologic Effects / Amylase Activity: Study evaluated various extracts for hematologic
parameters on Swiss mice and amylase activity on Wistar rats. Results showed an increase in the
haematological parameters (RBC, WBC, Hb, and PCV). There was also an increase in amylase content.
Results suggest potential use to prevent various complications in diabetes. (15)
• Antiulcer Activity / Antioxidant: Study evaluated the antiulcer activity of an aqueous extract of B.
rubra leaves on ethanol and pylorus ligated-induced gastric ulcers in rats. Results showed significant
and dose-dependent antiulcer activity and present a potential use in the treatment of gastric ulcers. (16)
• Fruit / Betacyanin / Antioxidant: Betacyanin extracted from the B alba fruit exhibited excellent
antioxidant activity, beneficial in scavenging free radicals. (18)
• Antimicrobial / Leaves and Stems: Study evaluated various extracts of leaves and stems for
antimicrobial activity against Gram-positive and Gram-negative bacteria and fungi. Methanol and
aqueous extracts of stems showed maximum activity against S. typhi and P. vulgaris. Ethanol extracts of
leaves and stems showed highest inhibition of B. subtilis and S. typhi. Antifungal activity was shown
against A. niger, C. albicans and R. stolonifers. (21)
• Cytotoxic / Antibacterial: Study evaluated the cytotoxic and antibacterial activity of Basella alba
whole plant extract. A methanolic extract showed significant growth inhibition on human cancer cell lines
and moderate activity against Pseudomonas aeruginosa and Bacillus subtilis. (23)
• Gastroprotective / Leaf Extracts: Study of aqueous and ethanol extracts of leaves were investigated
for antiulcer activity on rats in pylorus ligated and ethanol induced ulcer models. Results showed
significant dose-dependent gastroprotective effect substantiated by histopathological examination of
ulcerated stomachs of the animals. (24)
• Increased Testosterone and Estradiol Production: Study evaluated a methanol extract of Baselia
alba (MEBa) for cell viability, steroid production, and level of aromatase mRNA. Results showed no
effect on Leydig cell viability. There was significant stimulation of testosterone and estradiol production
and enhanced aromatase mRNA level. (25)
• Antiurolithiatic / Calcium Oxalate / Leaves: Study of leaves extract of Basella alba showed
admirable dissolving capacity of calcium oxalate crystals in vitro. (27)
• Mucilage Suspending Properties / Leaves: Study evaluated the suitability of mucilage isolated from
leaves of Basella alba leaves as suspending agent. Results showed B. alba leaves possess properties
to be used as a suspending agent, and superior than both tragacanth and bentonite. (28)
• Burn Wound Healing / Leaves: Study evaluated an aqueous extract of leaves of B. alba formulated
as a gel for burn wound healing activity. Results showed significant improvement in burn wound
contraction. (29)
• Nephroprotective / Gentamycin Induced Renal Toxicity: Study evaluated an ethanolic extract of B.
alba on gentamycin induced nephrotoxicity in Wistar albino rats. Results showed the extract protected
GM-induced nephrotoxicity, possibly by enhancing renal antioxidant agent. (30)
• Antimicrobial / Antioxidant / Leaves: Study evaluated dried and powdered leaves of B. alba for
antioxidant and antimicrobial activity. Results showed high activity in removing free radicals by DPPH
(72.3 ± 5.98) and ABTS (78 ± 4.04). 100 mg/m extract showed high activity against bacterial strains. (32)
• Hypocholesterolemic / Antiatherosclerotic / Leaves: Study evaluated the hypocholesterolemic and
antiatherosclerotic effects of B. alba leaf extracts in hypercholesterolemia induced rabbits. Treatment
significantly lowered TC, LDL, and triglycerides and increased HDL and antioxidant enzymes SOD and
GPx levels. Treatment also significantly suppressed aortic plaque formation. Results suggest a potential
alternative therapy for hypercholesterolemia and atherosclerosis. (33)
• Positive Effect on Vitamin A Stores: Daily consumption of cooked, pureed green leafy vegetables or
sweet potatoes has a positive effect on vitamin A stores in populations at risk of vitamin A deficiency.
(34)
• Hepatoprotective / Lead Induced Hepatotoxicity / Leaves: Study evaluated an ethanolic extract of
B. alba leaves on lead-induced hepatotoxicity in male Wistar rats. Results showed significant reduction
of alkaline phosphatase, AST, and ALT while glutathione was siginificantly increase. (35)
• Anti-Inflammatory / Leaves: Study evauated the anti-inflammatory activity of B. alba leaf extract in
experimentally induced inflammation in rats (carrageenan induced paw edema and cotton pellet
granuloma). Results showed significant and effective dose dependent anti-inflammatory activity. (36)
Availability
- Cultivated vegetable market produce.
- Wildcrafted.
- Seeds in the cybermarket.
© Godofredo U. Stuart Jr., M.D.
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