EXPERIMENT NO.

12 PREPARATION OF BUROW’S SOLUTION

 Burrow’s solution (5% aluminum subacetate)- is a liquid created with water and aluminum acetate.
 Synonym: Aluminum Acetate Topical solution and ―Liquor Burowii”.
 The solution is commonly used to relieved itching and stinging of irritated, inflamed skin and help stop the growth of bacteria and
fungus
 also known as aluminum acetate It is a salt that is used as a topical astringent. When the solution is applied to the affective area on the
skin it actually shrinks the body tissues and provides protective effect on the infected area. It is sold as a powder to mix or used as a
topical gel. It can be used against common foot problems including athlete’s foot, swelling, and excessive sweating and also for the
treatment of ear canal infection
 Another approved method of preparation of Burrow’s solution involves a double decomposition reaction of aluminum sulfate with
either lead acetate and calcium acetate to produce a solution of aluminum acetate and a precipitate of lead or calcium sulfate
 Pharm Use: commonly used in topical astringent and antiseptic preparation for the temporary relief of minor skin irritations such as
insect bites, athlete’s foot, rashes due to soaps, detergents and even rashes from jewelry
 The solution can also be used as an antibacterial preparation which is effective in inhibiting various microorganisms such as
methicillin-resistant Staphylococcus aureus

Identification Test
Test for Aluminum  Aluminum ion reacts with aqueous  Al(C2H3O2)3 + 3(NH4)(OH) → Al(OH)3 + 3(NH4) (C2H3O2)
Ion ammonia to produce a white gelatinous  Al(OH)3 + 3HCl → AlCl3 + 3 H2O
Aluminum ion + precipitate of Al(OH)3.
Aqueous ammonia  The dye aluminon is adsorbed by the
gelatinous Al(OH)3 precipitate to form a
red "lake" and a colorless solution.
Test for Acetate Ion  The reaction of between burrow’s solution, ethyl alcohol,
Burrow Solution+  fruity smell and concentrated sulfuric acid produce a fruity smell that
Ethyl alcohol came from the Ethyl acetate which is one of the products of
the reaction
Burrows Sultion +  red solution  The reaction of between burrow’s solution and Ferric
Ferric chloride chloride resulted to a red solution.