Pubmed Cochrane ClinicalKey

n = 41 n=2 n=3

Total
N = 46

Duplicated
article = 0
Inclusion Criteria

1. Retinoblastoma graded
After screened for
with ICRB/Reese Ellsworth duplication and assessed for 33 excluded articles :
grading system. eligibility
2. Provide information about n = 46 Study design (n=13), more
globe salvage rates. than 5 years study (n=13), less
3. More than 20 eyes included 33 articles excluded than 20 eyes in study (n=6)
in 1 study. and non primary
4. Less than 5 years. retinoblastoma (n=1).
5. Meta-analysis or systematic
review study design.
6. Primary Retinoblastoma.
Relevant studies concerned
Exclusion Criteria n = 13

1. Non english language.

2. In vitro and in vivo. 10 articles excluded
10 articles excluded :
Irrelevant topic (n=8) and full
text unavailable (n=2)
Relevant studies identified
and included for this study
N=3