Beta-1 vs Beta-2 receptor location

"You have 1 heart and 2 lungs":

Beta-1 are therefore primarily on heart.
Beta-2 primarily on lungs.
Show Details / Rate It
---Anonymous Contributor
 
Cisplatin: major side effect, action
"Ci-Splat-In":
Major side effect: Splat (vomiting sound)--vomiting so severe that anti-
nausea drug needed.
Action: Goes Into the DNA strand.
Show Details / Rate It
---Anonymous Contributor
 
Pupils in overdose: morphine vs. amphetamine
"MorPHINE: Fine. AmPHETamine: Fat":
Morphine overdose: pupils constricted (fine).
Amphetamine overdose: pupils dilated (fat).
Show Details / Rate It
---Anonymous Contributor
 
Atropine use: tachycardia or bradycardia
"A goes with B":
Atropine used clinically to treat Bradycardia.
Show Details / Rate It
---Anonymous Contributor
 
Reserpine action
Reserpine depletes the Reserves of catecholamines [and serotonin].
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Botulism toxin: action, related bungarotoxin
Action: "Botulism Bottles up the Ach so it can't be the released":
Related bungarotoxin: "Botulism is related to Beta Bungarotoxin (beta-, not
alpha-bungarotoxin--alpha has different mechanism).
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Ipratropium: action
Atropine is buried in the middle: iprAtropium, so it behaves like Atropine.
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Bleomycin: action
"Bleo-Mycin Blows My DNA to bits":
Bleomycin works by fragmenting DNA (blowing it to bits).
My DNA signals that its used for cancer (targeting self cells).
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Propranolol and related '-olol' drugs: usage
"olol" is just two backwards lower case b's.
Backward b's stand for "beta blocker".
· Beta blockers include acebutolol, betaxolol, bisoprolol, oxprenolol,
propranolol.
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Succinylcholine: action, use
Succinylcholine gets Stuck to Ach receptor, then Sucks ions in through open
pore.
You Suck stuff in through a mouth-tube, and drug is used for intubation.
Show Details / Rate It
---Anonymous Contributor
 

Metabolism enzyme inducers

"Randy's Black Car Goes Putt Putt and Smokes":
Rifampin
Barbiturates
Carbamazepine
Grisoefulvin
Phenytoin
Phenobarb
Smoking cigarettes
Show Details / Rate It
---Brad
 
Phenobarbitone: side effects
Children are annoying (hyperkinesia, irritability, insomnia, aggression).
Adults are dosy (sedation, dizziness, drowsiness).
Show Details / Rate It
---Afif El-khuffash Trinity College Dublin
 
Cholinergics (eg organophosphates): effects
If you know these, you will be "LESS DUMB":
Lacrimation
Excitation of nicotinic synapses
Salivation
Sweating
Diarrhea
Urination
Micturition
Bronchoconstriction
Show Details / Rate It
---Anonymous Contributor
 
Routes of entry: most rapid ways meds/toxins enter body
"Stick it, Sniff it, Suck it, Soak it":
Stick = Injection
Sniff = inhalation
Suck = ingestion
Soak = absorption
Show Details / Rate It
---Anonymous Contributor
 
Depression: 5 drugs causing it
PROMS:
Propranolol
Reserpine
Oral contraceptives
Methyldopa
Steroids
Show Details / Rate It
---Sunu George
 
Hepatic necrosis: drugs causing focal to massive necrosis
"Very Angry Hepatocytes":
Valproic acid
Acetaminophen
Halothane
Show Details / Rate It
---Calvin Sy University of Pittsburgh School of Medicine
 
Warfarin: action, monitoring
WePT:
Warfarin works on the extrinsic pathway and is monitored by PT.
Show Details / Rate It
---Marcus James Fidel Medical Student, University of New Mexico
 
Beta-blockers: side effects
"BBC Loses Viewers In Rochedale":
Bradycardia
Bronchoconstriction
Claudication
Lipids
Vivid dreams & nightmares
-ve Inotropic action
Reduced sensitivity to hypoglycaemia
Show Details / Rate It
---Anonymous Contributor
 
Zero order kinetics drugs (most common ones)
"PEAZ (sounds like pees) out a constant amount":
Phenytoin
Ethanol
Aspirin
Zero order
· Someone that pees out a constant amount describes zero order kinetics
(always the same amount out)
Show Details / Rate It
---Anonymous Contributor UHS-COM
 
Benzodiazepines: actions
"Ben SCAMs Pam into seduction not by brain but by muscle":
Sedation
anti-Convulsant
anti-Anxiety
Muscle relaxant
Not by brain: No antipsychotic activity.
Show Details / Rate It

Nitrofurantoin: major side effects

NitroFurAntoin:
Neuropathy (peripheral neuropathy)
Fibrosis (pulmonary fibrosis)
Anemia (hemolytic anemia)
Show Details / Rate It
---Joshua Goh Unimas: University Malaysia Sarawak
 
Steroids: side effects
BECLOMETHASONE:
Buffalo hump
Easy bruising
Cataracts
Larger appetite
Obesity
Moonface
Euphoria
Thin arms & legs
Hypertension/ Hyperglycaemia
Avascular necrosis of femoral head
Skin thinning
Osteoporosis
Negative nitrogen balance
Emotional liability
Show Details / Rate It
---Rob Cambridge University
 
Methyldopa: side effects
METHYLDOPA:
Mental retardation
Electrolyte imbalance
Tolerance
Headache/ Hepatotoxicity
psYcological upset
Lactation in female
Dry mouth
Oedema
Parkinsonism
Anaemia (haemolytic)
Show Details / Rate It
---Yazeed A. Oqaili King Saud University Medical College
 
Sodium valproate: side effects
VALPROATE:
Vomiting
Alopecia
Liver toxicity
Pancreatitis/ Pancytopenia
Retention of fats (weight gain)
Oedema (peripheral oedema)
Appetite increase
Tremor
Enzyme inducer (liver)
Show Details / Rate It
---Joshua Goh Unimas: University Malaysia Sarawak
 
Captopril (an ACE inhibitor): side effects
CAPTOPRIL:
Cough
Angioedema/ Agranulocystosis
Proteinuria/ Potassium excess
Taste changes
Orthostatic hypotension
Pregnancy contraindication/ Pancreatitis/ Pressure drop (first dose
hypertension)
Renal failure (and renal artery stenosis contraindication)/ Rash
Indomethacin inhibition
Leukopenia/ Liver toxicity
Show Details / Rate It
---Dr. Chetan Wasekar MBBS KEM Hospital
 
Lead poisoning: presentation
ABCDEFG:
Anemia
Basophilic stripping
Colicky pain
Diarrhea
Encephalopathy
Foot drop
Gum (lead line)
Show Details / Rate It
---Anonymous Contributor
 
Beta-blockers: main contraindications, cautions
ABCDE:
Asthma
Block (heart block)
COPD
Diabetes mellitus
Electrolyte (hyperkalemia)
Show Details / Rate It
---Anonymous Contributor
 
Lupus: drugs inducing it
HIP:
Hydralazine
INH
Procanimide
Show Details / Rate It
---Hodge/Gupta LSU Medicine FirmI
 
Lithium: side effects
LITH:
Leukocytosis
Insipidus [diabetes insipidus, tied to polyuria]
Tremor/ Teratogenesis
Hypothyroidism
Show Details / Rate It
---Robert O'Connor and Rinku Uberoi
 
SSRIs: side effects
SSRI:
Serotonin syndrome
Stimulate CNS
Reproductive disfunctions in male
Insomnia
Show Details / Rate It
---Robert O'Connor University College Dublin
 

Narcotic antagonists
The Narcotic Antagonists are NAloxone and NAltrexone.
· Important clinically to treat narcotic overdose.
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Inhalation anesthetics
SHINE:
Sevoflurane
Halothane
Isoflurane
Nitrous oxide
Enflurane
· If want the defunct Methoxyflurane too, make it MoonSHINE.
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Therapeutic dosage: toxicity values for most commonly
monitored medications
"The magic 2s":
Digitalis (.5-1.5) Toxicity = 2.
Lithium (.6-1.2) Toxicity = 2.
Theophylline (10-20) Toxicity = 20.
Dilantin (10-20) Toxicity = 20.
APAP (1-30) Toxicity = 200.
Show Details / Rate It
---Anonymous Contributor
 
Opioids: effects
BAD AMERICANS:
Bradycardia & hypotension
Anorexia
Diminished pupilary size
Analgesics
Miosis
Euphoria
Respiratory depression
Increased smooth muscle activity (biliary tract constriction)
Constipation
Ameliorate cough reflex
Nausea and vomiting
Sedations
Show Details / Rate It
---Sung H. Kim
 
Delerium-causing drugs
ACUTE CHANGE IN MS:
Antibiotics (biaxin, penicillin, ciprofloxacin)
Cardiac drugs (digoxin, lidocaine)
Urinary incontinence drugs (anticholinergics)
Theophylline
Ethanol
Corticosteroids
H2 blockers
Antiparkinsonian drugs
Narcotics (esp. mepridine)
Geriatric psychiatric drugs
ENT drugs
Insomnia drugs
NSAIDs (eg indomethacin, naproxin)
Muscle relaxants
Seizure medicines
Show Details / Rate It
---Muhammad Asif Iqbal Resident, SLU, MO
 
Disulfiram-like reaction inducing drugs
"PM PMT" as in Pre Medical Test in the PM:
Procarbazine
Metronidazole
Cefo (Perazone, Mandole, Tetan).
Show Details / Rate It
---Prashant A. Mehta
 
Zafirlukast, Montelukast, Cinalukast: mechanism, usage
"Zafir-luk-ast, Monte-luk-ast, Cina-luk-ast":
· Anti-Lukotrienes for Asthma.
· Dazzle your oral examiner: Zafirlukast antagonizes leukotriene-4.
Show Details / Rate It
---Oisin and Robert O'Connor UCC and University College Dublin
 
4-Aminopyradine (4-AP) use
"4-AP is For AP":
For AP (action potential) propagation in Multiple Sclerosis.
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Direct sympathomimetic catecholamines
DINED:
Dopamine
Isoproterenol
Norepinephrine
Epinephrine
Dobutamine
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Vir-named drugs: use
"-vir at start, middle or end means for virus":
· Drugs: Abacavir, Acyclovir, Amprenavir, Cidofovir, Denavir, Efavirenz,
Indavir, Invirase, Famvir, Ganciclovir, Norvir, Oseltamivir, Penciclovir,
Ritonavir, Saquinavir, Valacyclovir, Viracept, Viramune, Zanamivir, Zovirax.
Show Details / Rate It
---Robert O'Connor University College Dublin
 

Osmotic diuretics: members

GUM:
Glycerol
Urea
Mannitol
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Sulfonamide: major side effects
· Sulfonamide side effects:
Steven-Johnson syndrome
Skin rash
Solubility low (causes crystalluria)
Serum albumin displaced (causes newborn kernicterus and potentiation of
other serum albumin-binders like warfarin)
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Benzodiazepenes: antidote
"Ben is off with the flu":
Benzodiazepine effects off with Flumazenil.
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Narcotics: side effects
"SCRAM if you see a drug dealer":
Synergistic CNS depression with other drugs
Constipation
Respiratory depression
Addiction
Miosis
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Sex hormone drugs: male
"Feminine Males Need Testosterone":
Fluoxymesterone
Methyltestosterone
Nandrolone
Testosterone
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Ca++ channel blockers: uses
CA++ MASH:
Cerebral vasospasm/ CHF
Angina
Migranes
Atrial flutter, fibrillation
Supraventricular tachycardia
Hypertension
· Alternatively: "CHASM":
Cererbral vasospasm / CHF
Hypertension
Angina
Suprventricular tachyarrhythmia
Migranes
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Benzodiazepenes: drugs which decrease their metabolism
"I'm Overly Calm":
Isoniazid
Oral contraceptive pills
Cimetidine
· These drugs increase calming effect of BZDs by retarding metabolism.
Show Details / Rate It
---Anonymous Contributor
 
Tetracycline: teratogenicity
TEtracycline is a
TEratogen that causes staining of
TEeth in the newborn.
Show Details / Rate It
---
 
Warfarin: metabolism
SLOW:
· Has a slow onset of action.
· A quicK Vitamin K antagonist, though.
Small lipid-soluble molecule
Liver: site of action
Oral route of administration.
Warfarin
Show Details / Rate It
---Samuel Atom Baek-Kim
 
Myasthenia gravis: edrophonium vs. pyridostigmine
eDrophonium is for Diagnosis.
pyRIDostigmine is to get RID of symptoms.
Show Details / Rate It
---Samuel
 

Amiodarone: action, side effects

6 P's:
Prolongs action potential duration
Photosensitivity
Pigmentation of skin
Peripheral neuropathy
Pulmonary alveolitis and fibrosis
Peripheral conversion of T4 to T3 is inhibited -> hypothyroidism
Show Details / Rate It
---Archana
 
Morphine: effects
MORPHINES:
Miosis
Orthostatic hypotension
Respiratory depression
Pain supression
Histamine release/ Hormonal alterations
Increased ICT
Nausea
Euphoria
Sedation
Show Details / Rate It
---Dr. Chetan Wasekar, MBBS KEM Hospital
 
Monoamine oxidase inhibitors: members
"PIT of despair":
Phenelzine
Isocarboxazid
Tranylcypromine
· A pit of despair, since MAOs treat depression.
Show Details / Rate It
---Derek Obayashi Chicago Medical School
 
Antimuscarinics: members, action
"Inhibits Parasympathetic And Sweat":
Ipratropium
Pirenzepine
Atropine
Scopolamine
· Muscarinic receptors at all parasympathetic endings sweat glands in
sympathetic.
Show Details / Rate It
---Derek Obayashi Chicago Medical School
 
Patent ductus arteriosus: treatment
"Come In and Close the door":
INdomethacin is used to Close PDA.
Show Details / Rate It
---Milixa Fortuna UAG Medical Student
 
Etoposide: action, indications, side effect
"eTOPoside":
· Action:
Inhibits TOPoisomerase II
· Indications:
Testicular carcinoma
Oat cell carcinoma of lung
Prostate carcinoma
· Side effect:
Affects TOP of your head, causing alopecia
Show Details / Rate It
---Milixa Fortuna UAG Medical Student
 
Antibiotics contraindicated during pregnancy
MCAT:
Metronidazole
Chloramphenicol
Aminoglycoside
Tetracycline
Show Details / Rate It
---Kyongbin Baek
 
Lithium: side effects
LITHIUM:
Leukocytes Increased (leukocytosis)
Tremors
Hypothyroidism
Increased Urine
Moms beware (teratogenic)
Show Details / Rate It
---Marc Miller Sackler School of Medicine
 
Quinolones [and Fluoroquinolones]: mechanism
"Topple the Queen":
Quinolone interferes with Topoisomerase II.
Show Details / Rate It
---Samuel Atom Baek-Kim
 
MPTP: mechanism, effect
MPTP:
Mitochondrial Parkinson's-Type Poison.
· A mitochondrial poison that elicits a Parkinson's-type effect.
Show Details / Rate It
---Robert O'Connor University College Dublin
 

Hypertension: treatment
ABCD:
ACE inhibitors/ AngII antagonists (sometimes Alpha agonists also)
Beta blockers
Calcium antagonists
Diuretics (sometimes vasoDilators also)
Show Details / Rate It
---Mr. LW Mason and Dr. Sandeep Singh 4th Year Medical Student and Not Specified
 
Diuretics classification in order of site of action
"COLT Pee:"
· In their sequential site of action along the nephron:
Carbonic anhydrase inhibitors (at the proximal tubule)
Osmotic diuretics (at the Loop of Henle)
Loop diuretics (at the ascending loop)
Thiazides (at the distal tubule)
Potassium-sparing diuretics (at the collecting tubules)
· Diuretics make patient pee like a horse, hence "Colt Pee".
Show Details / Rate It
---Bruce Chou University of Illinois
 
Aspirin: side effects
ASPIRIN:
Asthma
Salicyalism
Peptic ulcer disease/ Phosphorylation-oxidation uncoupling/ PPH/ Platelet
disaggregation/ Premature closure of PDA
Intestinal blood loss
Reye's syndrome
Idiosyncracy
Noise (tinnitus)
Show Details / Rate It
---Dr. Chetan Wasekar, MBBS KEM Hospital
 
Clopidogrel: use
CLOPIdogrel is a drug that prevents
CLots, an Oral Platelet Inhibitor (OPI).
Show Details / Rate It
---Rinku Uberoi
 
Teratogenic drugs: major non-antibiotics
TAP CAP:
Thalidomide
Androgens
Progestins
Corticosteroids
Aspirin & indomethacin
Phenytoin
Show Details / Rate It
---Manpreet GMC Amritsar
 
Physostigmine vs. neostigmine
LMNOP:
Lipid soluble
Miotic
Natural
Orally absorbed well
Physostigmine
· Neostigmine, on the contrary, is:
Water soluble
Used in myesthenia gravis
Synthetic
Poor oral absorption
Show Details / Rate It
---Manpreet Saini GMC Amritsar
 
Prazocin usage
Prazocin sounds like an acronym of "praszz zour urine".
Therefore Prazocin used for urinary retention in BPH.
Show Details / Rate It
---Diljot Singh Bedi GMCH Chandigarh, India
 
Steroid side effects
CUSHINGOID:
Cataracts
Ulcers
Skin: striae, thinning, bruising
Hypertension/ Hirsutism/ Hyperglycemia
Infections
Necrosis, avascular necrosis of the femoral head
Glycosuria
Osteoporosis, obesity
Immunosuppression
Diabetes
Show Details / Rate It
---Anonymous Contributor
 
Beta blockers with CYP2D6 polymorphic metabolism
"I Met Tim Carver, the metabolic polymorph":
· The following beta blockers require dose adjustment due to CYP2D6
polymorphic metabolism:
Metoprolol
Timolol
Carvedilol
(in patients with lower or higher than normal CYP2D6 activity)
Show Details / Rate It
---David Shprecher Lake Erie College of Osteopathic Medicine
 
Beta blockers with intrinsic sympathomimetic activity
Picture diabetic and asthmatic kids riding away on a cart that rolls on
pinwheels.
Pindolol and Carteolol have high and moderate ISA respectively, making
them acceptable for use in some diabetics or asthmatics despite the fact that
they are non-seletive beta blockers.

Show Details / Rate It

---David Shprecher Lake Erie College of Osteopathic Medicine
 

Benzodiazapines: ones not metabolized by the liver (safe to use

in liver failure)
LOT:
Lorazepam
Oxazepam
Temazepam
Show Details / Rate It
---Lorne Basskin Butler University College of Pharmacy and Health Sciences
 
Vigabatrin: mechanism
Vi-GABA-Tr-In:
Via GABA Transferase Inhibition
Show Details / Rate It
---Anonymous Contributor
 
TB: antibiotics used
STRIPE:
STreptomycin
Rifampicin
Isoniazid
Pyrizinamide
Ethambutol
Show Details / Rate It
---Sushant Varma Medical student, University of Sheffield, UK
 
Propythiouracil (PTU): mechanism
It inhibits PTU:
Peroxidase/ Peripheral deiodination
Tyrosine iodination
Union (coupling)
Show Details / Rate It
---Dr. Atif Farooq Khawaja and Mediha Farooq Rawalpindi Medical College, Pakistan/
Gujranwala
 
Enoxaprin (prototype low molecular weight heparin): action,
monitoring
EnoXaprin only acts on factor Xa.
Monitor Xa concentration, rather than APTT.
Show Details / Rate It
---Dr. Atif Farooq Khawaja Rawalpindi Medical College, Pakistan, Gujranwala
 
Beta-blockers: nonselective beta-blockers
"Tim Pinches His Nasal Problem" (because he has a runny nose...):
Timolol
Pindolol
Hismolol
Naldolol
Propranolol
Show Details / Rate It
---Hugo M. Rodriguez, MD University of Virginia Roanoke-Salem Program
 
Nicotinic effects
MTWTF (days of week):
Mydriasis/ Muscle cramps
Tachycardia
Weakness
Twitching
Hypertension/ Hyperglycemia
Fasiculation
Show Details / Rate It
---John Nguyen University of Texas Medical Branch
 
Muscarinic effects
SLUG BAM:
Salivation/ Secretions/ Sweating
Lacrimation
Urination
Gastrointestinal upset
Bradycardia/ Bronchoconstriction/ Bowel movement
Abdominal cramps/ Anorexia
Miosis
Show Details / Rate It
---John Nguyen University of Texas Medical Branch
 
Phenytoin: adverse effects
PHENYTOIN:
P-450 interactions
Hirsutism
Enlarged gums
Nystagmus
Yellow-browning of skin
Teratogenicity
Osteomalacia
Interference with B12 metabolism (hence anemia)
Neuropathies: vertigo, ataxia, headache
Show Details / Rate It
---Ram Mohan SVRR Hospital Tirupathi, India
 
Gynaecomastia-causing drugs
DISCOS:
Digoxin
Isoniazid
Spironolactone
Cimetidine
Oestrogens
Stilboestrol
Show Details / Rate It
---Nasseri University of Sheffield
 

Parkinsonism: drugs
SALAD:
Selegiline
Anticholinenergics (trihexyphenidyl, benzhexol, ophenadrine)
L-Dopa + peripheral decarboxylase inhibitor (carbidopa, benserazide)
Amantadine
Dopamine postsynaptic receptor agonists (bromocriptine, lisuride, pergolide)
Show Details / Rate It
---Dr. Harsh Sharma
 
Morphine: effects at mu receptor
PEAR:
Physical dependence
Euphoria
Analgesia
Respiratory depression
Show Details / Rate It
---Robert Copeland Howard University College of Medicine
 
Thrombolytic agents
USA:
Urokinase
Streptokinase
Alteplase (tPA)
Show Details / Rate It
---Dr. Harsh Sharma BJMC, Pune, India
 
Anticholinergic side effects
"Know the ABCD'S of anticholinergic side effects":
Anorexia
Blurry vision
Constipation/ Confusion
Dry Mouth
Sedation/ Stasis of urine
Show Details / Rate It
---Youngrin Kim University of Rochester School of Medicine and Dentistry
 
Teratogenic drugs
"W/ TERATOgenic":
Warfarin
Thalidomide
Epileptic drugs: phenytoin, valproate, carbamazepine
Retinoid
ACE inhibitor
Third element: lithium
OCP and other hormones (eg danazol)
Show Details / Rate It
---Anthony Chan
 
Antiarrhythmics: classification I to IV
MBA College
· In order of class I to IV:
Membrane stabilizers (class I)
Beta blockers
Action potential widening agents
Calcium channel blockers
Show Details / Rate It
---Dr. Harsh Sharma BJMC, Pune, India
 
Epilepsy types, drugs of choice
"Military General Attacked Weary Fighters Pronouncing 'Veni Vedi Veci' After
Crushing Enemies":
· Epilepsy types:
Myoclonic
Grand mal
Atonic
West syndrome
Focal
Petit mal (absence)
· Respective drugsy:
Valproate
Valproate
Valproate
ACTH
Carbamazepine
Ethosuximide
Show Details / Rate It
---Dr. Harsh Sharma BJMC, Pune, India
 
Respiratory depression inducing drugs
"STOP breathing":
Sedatives and hypnotics
Trimethoprim
Opiates
Polymyxins
Show Details / Rate It
---Dr. Harsh Sharma BJMC, Pune, India
 
Pulmonary infiltrations inducing drugs
"Go BAN Me!":
Gold
Bleomycin/ Busulphan/ BCNU
Amiodarone/ Acyclovir/ Azathioprine
Nitrofurantoin
Melphalan/ Methotrexate/ Methysergide
Show Details / Rate It
---Dr. Harsh Sharma BJMC, Pune, India
 
Migraine: prophylaxis drugs
"Very Volatile Pharmacotherapeutic Agents For Migraine Prophylaxis":
Verpamil
Valproic acid
Pizotifen
Amitriptyline
Flunarizine
Methysergide
Propranolol
· Bare bones version [eg Lippincott's two], just Migraine Prophylaxis, as
above.
Show Details / Rate It
---Dr. Harsh Sharma BJMC, Pune, India

HMG-CoA reductase inhibitors (statins): side effects,

contraindications, interactions
HMG-CoA:
· Side effects:
Hepatotoxicity
Myositis [aka rhabdomyolysis]
· Contraindications:
Girl during pregnancy/ Growing children
· Interactions:
Coumarin/ Cyclosporine
Show Details / Rate It
---Dr. Atif Farooq Khawaja Rawalpindi Medical College, Pakistan, Gujranwala
 
Therapeutic index: formula
TILE:
TI = LD50 / ED50
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Antirheumatic agents (disease modifying): members
CHAMP:
Cyclophosphamide
Hydroxycloroquine and choloroquinine
Auranofin and other gold compounds
Methotrexate
Penicillamine
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Auranofin, aurothioglucose: category and indication
Aurum is latin for "gold" (gold's chemical symbol is Au).
Generic Aur- drugs (Auranofin, Aurothioglucose) are gold compounds.
· If didn't learn yet that gold's indication is rheumatoid arthritis, AUR- Acts
Upon Rheumatoid.
Show Details / Rate It
---Robert O'Connor University College Dublin
 
Antiarrhythmics: class III members
BIAS:
Bretylium
Ibutilide
Amiodarone
Sotalol
Show Details / Rate It
---Dr. Harsh Sharma and Robert O'Connor BJMC, Pune, India and University College Dublin
 
MAOIs: indications
MAOI'S:
Melancholic [classic name for atypical depression]
Anxiety
Obesity disorders [anorexia, bulemia]
Imagined illnesses [hypochondria]
Social phobias
· Listed in decreasing order of importance.
· Note MAOI is inside MelAnchOlIc.
Show Details / Rate It
---Robert O'Connor University College Dublin
 
SIADH-inducing drugs
ABCD:
Analgesics: opioids, NSAIDs
Barbiturates
Cyclophosphamide/ Chlorpromazine/ Carbamazepine
Diuretic (thiazide)
Show Details / Rate It
---Anthony Chan
 
K+ increasing agents
K-BANK:
K-sparing diuretic
Beta blocker
ACEI
NSAID
K supplement
Show Details / Rate It
---Anthony Chan
 
Diuretics: thiazides: indications
"CHIC to use thiazides":
CHF
Hypertension
Insipidous
Calcium calculi
Show Details / Rate It
---Anonymous Contributor
 
Ribavirin: indications
RIBAvirin:
RSV
Influenza B
Arenaviruses (Lassa, Bolivian, etc.)
Show Details / Rate It
---Robert O'Connor University College Dublin

Adrenoceptors: vasomotor function of alpha vs. beta

ABCD:
Alpha = Constrict.
Beta = Dilate.
Show Details / Rate It
---Anonymous Contributor
 
Beta 1 selective blockers
"BEAM ONE up, Scotty":
Beta 1 blockers:
Esmolol
Atenolol
Metropolol
Show Details / Rate It
---Anonymous Contributor
 
Opiods: mu receptor effects
"MD CARES":
Miosis
Dependency
Constipation
Analgesics
Respiratory depression
Euphoria
Sedation
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---Sung Hoon Kim El Paso, TX
 
Cancer drugs: time of action between DNA->mRNA
ABCDEF:
Alkylating agents
Bleomycin
Cisplastin
Dactinomycin/ Doxorubicin
Etoposide
Flutamide and other steroids or their antagonists (eg tamoxifen, leuprolide)
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---Sung Hoon Kim El Paso, TX
 
Busulfan: features
ABCDEF:
Alkylating agent
Bone marrow suppression s/e
CML indication
Dark skin (hyperpigmentation) s/e
Endrocrine insufficiency (adrenal) s/e
Fibrosis (pulmonary) s/e
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---Sung Hoon Kim El Paso, TX
 
Tricyclic antidepressants: members worth knowing
"I have to hide, the CIA is after me":
Clomipramine
Imipramine
Amitrptyline
· If want the next 3 worth knowing, the DND is also after me:
Desipramine
Norrtriptyline
Doxepin
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---Dr. Enrique Cifuentes University Autonomus of Guadalajara
 
Asthma drugs: leukotriene inhibitor action
zAfirlukast: Antagonist of lipoxygenase
zIlueton: Inhibitor of LT receptor
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---Mumtaz Ali Shah 2000 graduate, Khyber Medical College, Pakistan
 
Torsades de Pointes: drugs causing
APACHE:
Amiodarone
Procainamide
Arsenium
Cisapride
Haloperidol
Eritromycin
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---Flavio Nacul Federal University of Rio de Janeiro
 
Serotonin syndrome: components
Causes HARM:
Hyperthermia
Autonomic instability (delirium)
Rigidity
Myoclonus
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---Anonymous Contributor
 
Beta blockers: B1 selective vs. B1-B2 non-selective
A through N: B1 selective: Acebutalol, Atenolol, Esmolol, Metoprolol.
O through Z: B1, B2 non-selective: Pindolol, Propanalol, Timolol.
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---Amir Butt Quaid-e-Azam Medical College, Bahawalpur, Pakistan

Morphine: side-effects
MORPHINE:
Myosis
Out of it (sedation)
Respiratory depression
Pneumonia (aspiration)
Hypotension
Infrequency (constipation, urinary retention)
Nausea
Emesis
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---Tony Duffy Medical Student Glasgow
 
Corticosteroids: adverse side effects
CUSHINGS BAD MD:
Cataracts
Up all night (sleep disturbances)
Suppression of HPA axis
Hypertension/ buffalo Hump
Infections
Necrosis (avascular)
Gain weight
Striae
Bone loss (osteoporosis)
Acne
Diabetes
Myopathy, moon faces
Depression and emotional changes
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---Anita Dunn University of Toronto
 
Tricyclic antidipressents (TCA): side effects
TCA'S:
Thrombocytopenia
Cardiac (arrhymia, MI, stroke)
Anticholinergic (tachycardia, urinary retention, etc)
Seizures
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---Anonymous Contributor
 
Bromocriptine [for USA gang members]
The CRYPTS are an LA street gang that likes to smoke DOPE.
BromoCRYPTine is a DOPamine agonist.
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---Mario Cruz Albany Medical College
 
Beta blockers: members
"The NEPAL Prime Minister":
Timolol
Nadolol
Esmolol
Pindolol
Atenolol
Labetalol
Propranolol
Metoprolol
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---Javaid H. Wani Spartan University School of Medicine, St. Lucia, W.I.
 
Microtubules: drugs that act on microtubules.
"The MicroTubule Growth Voiding Chemicals":
Thiabendazole
Mebendazole
Taxol
Griseofulvin
Vincristine/ Vinblastine
Colchicine
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---Javaid H. Wani, Ph.D. Spartan University School of Medicine
 
Insulin: mixing regular insulin and NPH
"Not Ready, Ready Now":
Air into NPH
Air into Regular
Draw up Regular
Draw up NPH
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---Adrian Hordon LVN student
 
Benzodiazepins: 3 members that undergo extrahepatic
metabolism
"Outside The Liver":
Oxazepam
Temazepam
Lorazepam
These undergo extrahepatic metabolism and do not form active metabolites.
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---Anonymous Contributor
 
Guanethidine: mechanism
GuaNEthidine prevents NE (norepinephrine) release.
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---Anonymous Contributor
 
Parasympathetic vs. sympathetic neurotransmitters
"No sympathy for a Pair of Aces":
Norepinephren is secreted in by the Sympathetic nervous system while
Acetylcholine is secreted in the Parasympathetic nervous system.
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---Jimbo Vasa Pharmacy University of Illinois at Chicago

Opiates: overdose findings

"Cool to the touch, unresponsive to pain,
Hunger diminished, and scars over vein.
Pupils pinpointed, and blood pressure low,
Urine diminished, and breathing is slow."
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---Anonymous Contributor
 
Cocaine: cardiovascular effect
COcaine causes blood vessels to
COnstrict (unlike other local anesthetics which cause vasodilation).
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---Anonymous Contributor
 
Aminoglycosides: common characteristics
AMINO:
Active Against Aerobic gram negative
Mechanism of resistance are Modifying enzymes
Inhibit protein synthesis by binding to 30S subunit
Nephrotoxic
Ototoxic
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---David H. Chafey Ponce School of Medicine
 
Sulfonamides: common characteristics
SULFA:
Steven-Johnson syndrome/ Skin rash / Solubility low
Urine precipitation/ Useful for UTI
Large spectrum (gram positives and negatives)
Folic acids synthesis blocker (as well as synthesis of nucleic acids)
Analog of PABA
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---David H. Chafey Ponce School of Medicine
 
Diuretics: groups
"Leak Over The CAN":
Loop diuretics
Osmotics
Thiazides
Carbonic anhydrase inhibitors
Aldosterone inhibitors
Na (sodium) channel blockers
· Note: "leak" is slang for urination and "can" is slang for a toilet.
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---CY UWA
 
Thalidomide: effect on cancer cells
"Thalidomide makes the blood vessels hide":
Use thalidomide to stop cancer cells from growing new blood vessels.
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---Gital Karamchandani Northeastern Ohio Universities College of Medicine
 
Tuberculosis: treatment
If you forget your TB drugs, you'll die and might need a PRIEST":
Pyrazinamide
Rifampin
Isoniazid (INH)
Ethambutol
STreptomycin
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---Hugo Basterrechea Ross University School of Medicine
 
Warfarin: interactions
ACADEMIC QACS:
Amiodarone
Cimetidine
Aspirin
Dapsone
Erythromycin
Metronidazole
Indomethacin
Clofibrates
Quinidine
Azapropazone
Ciprofloxacin
Statins
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---Andrew Fok Birmingham Medical School
 
Patent ductus arteriosus: which prostaglandin keeps it open
kEEp opEn with prostaglandin E.
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---Anonymous Contributor
 
Carbamazepine (CBZ): use
CBZ:
Cranial Nerve V (trigeminal) neuralgia
Bipolar disorder
Zeisures
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RTI: drugs to treat viral respiratory infections

"You'd get a respiratory infection if you shoot an ARO (arrow) laced with
viruses into the lungs":
ARO:
Amantadine
Rimantadine
Oseltamivir
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---Anonymous Contributor USC
 
Medication administration: short checklist
TRAMP:
· Before dispensing medication, ensure have correct:
Time
Route
Amount
Medication
Patient
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---Lori Registered Nurse