Professional Documents
Culture Documents
PASS Session 1
PASS Session 1
Learning Objectives:
1. Understand the biological functions and controls of enzymes
2. Explain the metabolic functions of the liver in energy supply
3. Determine the pathways of glycogen synthesis and breakdown
4. Understand the different forms of energy supply for different tissues and their
pathways
5. Identify the effects of body fluid compartments, concentration of fluids and their
significance on treatment
6. Identify the different types of tissues and their functions
Questions:
1a. Which of the following is/are correct?
A. Catabolism and active transport are both endergonic reactions
B. Anabolism uses energy produced by catabolism
C. A competitive inhibitor binds to the active site, while an uncompetitive inhibitor
binds to the allosteric site
D. The main function of an enzyme is to lower the activation energy of a reaction
1b. In the case of noncompetitive inhibition of the enzyme, the inhibitor:
A. Is structurally related to the substrate
B. Binds to the domain of the enzyme different from the substrate binding site
C. Is always a metal ion
D. Is covalently bound to the enzyme
2. A deficiency of oxaloacetate would most likely increase the metabolism of which
potential energy source?
A. Acetyl Co-A
B. Leucine, Glutamine
C. Alanine, Aspartate
D. Acetoacetyl-coA
3. Fill in the blanks with the correct answer.
4. Complete the table.
Tissue State Main source of energy
Moderately active
Extremely active
Starvation
Myocytes Normal
Brain Normal
Starvation
Compartments(I
CF, ECF →
plasma/interstit
ial fluid)
When is it used
SAQ: A patient has lost 1 liter of blood, and you are required to restore that volume
quickly while waiting for a blood transfusion to arrive from the blood bank.
a) Which would be better to administer : 5% dextrose in water or 0.9% Nacl in
water? (Hint: Think about how these solutes distribute in the body.) Defend
your choice.
b) How much of your solution of choice would you need to administer to return
blood volume to normal?
6. Identify the function of the tissue in the diagram
I. Protection
II. Secretion
III. Lubrication
IV. Absorption
A. I & II only
B. II & III only
C. I, II & IV only
D. II, III & IV only
E. I, II, III & IV
7. Which of the following is not a fixed connective tissue?
A. D.
B. E.
C.
8. Describe how the branches in glycogen are removed? (SAQ)
9. Why is liver glycogen used instead of muscle glycogen when fasting?
A. Muscle cells convert glucose to lactate
B. Muscle cells have no debranching enzyme
C. Muscle cells have no glucose-6-phosphatase
D. Muscle cells directly convert glycogen to glucose-1-phosphate
E. Liver supplies enough glucose and there is no need for muscle to metabolise
glycogen.
10. Which is not correctly matched with its embryological derivative?
A. Dorsal root ganglia-neural tube(ectoderm)
B. Skull-endoderm
C. Epithelium of GIT- endoderm
D. Blood- mesoderm
11) Compare cardiac, skeletal and smooth muscle cells.