Migraines commonly occur in children and can significantly impact their school, social, and home life. Appropriate diagnosis and monitoring is important. Both pharmacological and non-pharmacological therapies should be used to treat migraines in children. Common non-prescription medications include ibuprofen and acetaminophen, while triptans are a first-line prescription option. Several other prescription medications are also used preventively. Further research is still needed but treatment options continue to expand based on new evidence regarding short-term and preventive drugs as well as non-drug strategies.
Migraines commonly occur in children and can significantly impact their school, social, and home life. Appropriate diagnosis and monitoring is important. Both pharmacological and non-pharmacological therapies should be used to treat migraines in children. Common non-prescription medications include ibuprofen and acetaminophen, while triptans are a first-line prescription option. Several other prescription medications are also used preventively. Further research is still needed but treatment options continue to expand based on new evidence regarding short-term and preventive drugs as well as non-drug strategies.
Migraines commonly occur in children and can significantly impact their school, social, and home life. Appropriate diagnosis and monitoring is important. Both pharmacological and non-pharmacological therapies should be used to treat migraines in children. Common non-prescription medications include ibuprofen and acetaminophen, while triptans are a first-line prescription option. Several other prescription medications are also used preventively. Further research is still needed but treatment options continue to expand based on new evidence regarding short-term and preventive drugs as well as non-drug strategies.
sought. Several triptans are currently under investiga- 9. Hershey AD.
Current approaches to the diagnosis and
tion for their effectiveness in children (Reference 29). management of paediatric migraine. Lancet Neurol A few trials are also investigating topiramate for use in 2010;9:190–204. preventing migraines in children 12 years and older. 10. Fenichel GM. Headache. In: Clinical Pediatric Neurology, 5th ed. Philadelphia: Elsevier Saunders, 2005:77–89. CONCLUSIONS 11. Pinhas-Hamiel O, Frumin K, Gabis L, Mazor- Migraines occur commonly in the pediatric population. Aronovich K, Modan-Moses D, Reichman B, et al. They can be debilitating and affect the school, social, Headaches in overweight children and adolescents and home life of a child. Appropriate diagnosis and referred to a tertiary-care center in Israel. Obes Res close follow-up with monitoring are recommended 2008;16:659–63. for all patients. Nonpharmacologic and pharmacologic 12. International Headache Society. International therapies should be used in children with a diagnosis of Classification of Headache Disorders, 2nd ed. migraines to improve symptoms and increase quality of Cephalalgia 2004;24:S23–S136. life. Biofeedback, relaxation techniques, and stress man- 13. Blume HK, Szperka CL. Secondary causes of agement are nonpharmacologic therapies to consider in headaches in children: when it isn’t a migraine. Pediatr children with migraines. Ibuprofen or acetaminophen Ann 2010;39:431–9. is an appropriate first-line short-term nonprescription 14. Winner P, Rothner AD, Putnam DG, Asgharnejad treatment option, with the triptan class considered a M. Demographic and migraine characteristics of first-line prescription treatment option for children adolescents with migraine: Glaxo Wellcome clinical and adolescents. Several medications (e.g., propranolol, trials’ database. Headache 2003;43:451–7. amitriptyline, valproic acid, topiramate) have been used 15. Gelfand AA, Fullerton HJ, Goadsby PJ. Child for prophylaxis therapy in children. The understanding neurology: migraine with aura in children. Neurology of this disease state, assessment, and treatment will con- 2010;75:e16–e19. tinue to change as they are further studied. Migraine 16. Hershey AD, Powers SW, Vockell AL, LeCates management will continue to expand as evidence is dis- S, Kabbouche MA, Maynard MK. PedMIDAS: covered regarding new short-term and preventive drugs development of a questionnaire to assess disability of as well as nonpharmacologic strategies. migraines in children. Neurology 2001;57:2034–9. 17. Powers SW, Patton SR, Hommel KA, Hershey AD. REFERENCES Quality of life in childhood migraines: clinical impact and comparison to other chronic illnesses. Pediatrics 1. Kabbouche MA, Linder SL. Acute treatment of 2003;112:e1–e5. pediatric headache in the emergency department and 18. Hershey AD, Kabbouche MA, Powers SW. Treatment inpatient settings. Pediatr Ann 2005;34:466–71. of pediatric and adolescent migraine. Pediatr Ann 2. Hershey AD, Winner PK. Pediatric migraine: 2010;39:416–23. recognition and treatment. J Am Osteopath Assoc 19. Migraine Headache. AAN Summary of Evidence- 2005;105:2S–8S. Based Guidelines for Clinicians. St. Paul, MN: 3. Silberstein SD. Practice parameter: evidence-based American Academy of Neurology, 2009. Available at guidelines for migraine headache (an evidence-based www.aan.com/practice/guideline/uploads/120.pdf. review). Neurology 2000;55:754–62. Accessed November 7, 2011. 4. Bigal ME, Lipton RB. The prognosis of migraine. Curr 20. Van den Bergh V, Amery WK, Waelkens J. Trigger Opin Neurol 2008;21:301–8. factors in migraine: a study conducted by the Belgian 5. Lewis D, Ashwal S, Hershey A, Hirtz D, Yonker M, Migraine Society. Headache 1987;27:191–6. Silberstein S, et al. Practice parameter: pharmacological 21. Slater SK, Nelson TD, Kabbouche M, Lecates SL, treatment of migraine headache in children and Horn P, Segers A, Manning P, et al. A randomized, adolescents: report of the American Academy of double-blinded, placebo-controlled, crossover, Neurology Quality Standards Subcommittee and the add-on study of coenzyme Q10 in the prevention Practice Committee of the Child Neurology Society. of pediatric and adolescent migraine. Cephalalgia Neurology 2004;63:2215–24. 2011;31:897–905. 6. Dooley JM, Pearlman EM. The clinical spectrum of 22. Eiland LS, Hunt MO. The use of triptans for pediatric migraine in children. Pediatr Ann 2010;39:408–15. migraines. Paediatr Drugs 2010;12:379–89. 7. Lewis D. Pediatric migraines. Neurol Clin 23. Chan VW, McCabe EJ, MacGregor DL. Botox 2009;27:481–501. treatment for migraine and chronic daily headache in 8. Silberstein SD. Migraine. Lancet 2004;363:381–91. adolescents. J Neurosci Nurs 2009;41:235–43.