According to the USMLE, each Step 1 exam covers content related to the following

traditionally-defined disciplines:

 Anatomy
 Behavioral sciences
 Biochemistry
 Biostatistics and epidemiology
 Microbiology
 Pathology
 Pharmacology
 Physiology

Other content that’s covered is related to the following disciplinary areas:

 Aging
 Genetics
 Immunology
 Molecular and cell biology
 Nutrition

Step 1 is a broadly based, integrated examination. Test items commonly require you to perform
one or more of the following tasks:

 Interpret graphic and tabular material

 Identify gross and microscopic pathologic and normal specimens
 Apply basic science knowledge to clinical problems

USMLE STEP 1 CLASSIFICATION