Ph.D.

Program in Drug Discovery and

Development Industry
Journal papers published by our teachers
(date to 20200731)
 Journal papers published-2017
Associations of estradiol levels and genetic polymorphisms of inflammatory
genes with the risk of ischemic stroke. Hsieh YC(謝宜蓁), Tu SH, Su CT, Cho
EC, Wu CH, Hsieh MC, Lin SY, Liu YR, Hung CS*, Chiou HY*.Journal of
Biomedical Science. 2017 FEB 15; 163(1)131-138.【IF: 3.466; Ranking:
46/133】

Real-time imaging of intestinal bacterial β-glucuronidase activity by

hydrolysis of a fluorescent probe. Chen M, Cheng KW, Chen YJ, Wang CH,
Cheng TC, Chang KC, Kao AP, Chuang KH(莊國祥)#. Scientific Reports.
2017 JUN 09; 7(1): 3142.【IF: 4.122; Ranking: 12/64】

In Vitro Biocompatibility, Radiopacity, and Physical Property Tests of Nano-

Fe3O4 Incorporated Poly-L-lactide Bone Screws. Wang HT, Chiang PC,
Tzeng JJ, Wu TL, Pan YH, Chang WJ, Huang HM(黃豪銘)#. Polymer. 2017
MAY 26, 9(191): 1-11. 【IF: 3.483; Ranking: 14/87】

Data Sources: Research Performance Index System

 Journal papers published-2017
Associations of estradiol levels and genetic polymorphisms of inflammatory
genes with the risk of ischemic stroke. Hsieh YC(謝宜蓁), Tu SH, Su CT, Cho
EC, Wu CH, Hsieh MC, Lin SY, Liu YR, Hung CS*, Chiou HY*.Journal of
Biomedical Science. 2017 FEB 15; 163(1)131-138.【IF: 3.466; Ranking:
46/133】

Real-time imaging of intestinal bacterial β-glucuronidase activity by

hydrolysis of a fluorescent probe. Chen M, Cheng KW, Chen YJ, Wang CH,
Cheng TC, Chang KC, Kao AP, Chuang KH(莊國祥)#. Scientific Reports.
2017 JUN 09; 7(1): 3142.【IF: 4.122; Ranking: 12/64】

In Vitro Biocompatibility, Radiopacity, and Physical Property Tests of Nano-

Fe3O4 Incorporated Poly-L-lactide Bone Screws. Wang HT, Chiang PC,
Tzeng JJ, Wu TL, Pan YH, Chang WJ, Huang HM(黃豪銘)#. Polymer. 2017
MAY 26, 9(191): 1-11. 【IF: 3.483; Ranking: 14/87】

Data Sources: Research Performance Index System

 Journal papers published-2017
Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an
in Silico Virtual Screening Approach. Hsu KC, Liu CY, Lin TE, Hsieh JH, Sung
TY, Tseng HJ, Yang JM, Huang WJ(黃偉展)#. Scientific Reports. 2017 JUN 12;
7(1): 3228.【IF: 4.122; Ranking: 12/64】

The Novel HDAC8 Inhibitor WK2-16 Attenuates Lipopolysaccharide-

Activated Matrix Metalloproteinase-9 Expression in Human Monocytic Cells
and Improves Hypercytokinemia In Vivo. Jan JS , Chou YC, Cheng YW, Chen
CK, Huang WJ, H George(蕭哲志)#. International Journal of Molecular
Sciences. 2017 JUN 29; 18(7): 1394.【IF: 3.687 Ranking: 52/171】

Early vertebroplasty associated with a lower risk of mortality and respiratory failure
in aged patients with painful vertebral compression fractures: a population-based
cohort study in Taiwan. Lin JH, Chien LN, Tsai WL, Chen LY, Chiang YH, Hsieh
YC(謝 宜蓁 )#. The Spine Journal. 2017 SEP 1; 7(9):1310-1318.【IF: 3.119
Ranking: 11/77】

Data Sources: Research Performance Index System

 Journal papers published-2017
FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core
fucosylation. Tu CF, Wu MY, Lin YC, Reiji Kannagi and Yang RB(楊瑞彬)#.
Breast Cancer Research. 2017 Oct 5;19(1):111.【IF: 6.142 Ranking: 35/223】

Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled

Derivative. Chen LC, Hsu KC, Chiou LC, Tseng HJ, Huang WJ (黃偉展)#,
Molecule. 2017 Nov 4; 22(11): 1897.【IF: 3.098 Ranking: 68/171】

Development of TNF-alpha vaccine for inflammatory diseases. HuangFu, WC (皇

甫維君) and Chin, LT. Cytokine. 2017 Dec; 100: 112.【IF: 3.514 Ranking:
101/293】

Data Sources: Research Performance Index System

 Journal papers published-2018
Discovery of aliphatic-chain hydroxamates containing indole derivatives with
potent class I histone deacetylase inhibitory activities. Chao SW, Chen LC, Yu CC,
Liu CY, Tony EL, Guh JH, Wang CY, Chen CY, Hsu KC, Huang WJ(黃偉展)#.
European Journal of Medicinal Chemistry. 2018 Jan 1; 143: 792-805.【IF: 4.816
Ranking: 4/59】

Guanylyl cyclase-G is an alarm pheromone receptor in mice. Chao YC, Fleischer J,

Yang, RB (楊瑞彬)#. EMBO Journal. 2018 Jan 4; 37(1): 39-49.【IF: 10.557
Ranking: 13/293】

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)

promotes EGF receptor signaling of oral squamous cell carcinoma metastasis via
the complex N-glycosylation. Chiang WF, TM, Chang CC(張哲菖), Pan SH ,
Changou CA, Chang TH, Lee KH, Wu SY, Chen YF, Chuang KH, Shieh DB, Chen
YL, CC Tu, Tsui WL and MH Wu. Oncogene. 2018 Jan 4; 37(1): 116-127. 【IF:
6.854 Ranking: 33/293】

Data Sources: Research Performance Index System

 Journal papers published-2018
Sex hormone-binding globulin (SHBG) is a potential early diagnostic biomarker
for gastric cancer. Cheng CW, Chang CC(張哲菖), Patria YN, Chang RT, Liu YR,
Li FA, Shih HM, Lin CY. Cancer Medicine. 2018 Jan; 7(1): 64-74.【IF: 3.202
Ranking: 111/223】

New Terpenoids from Chamaecyparis formosensis (Cupressaceae) Leaves with

Modulatory Activity on Matrix Metalloproteases 2 and 9. Chang ML, Mei HC,
Kuo IC, Hsiao G, Kuo YH, Lee CK(李慶國)#. Molecule. 2018 Mar 7; 23(3).
【IF: 3.098 Ranking: 68/171】

A Nov el Dual HDAC6 and Tubulin Inhibitor, MPT0B451, Displays Anti-tumor

Ability in Human Cancer Cells in Vitro and in Vivo. Wu YW, Hsu KC, Lee HY,
Huang TC, Lin TE, Chen YL, Sung TY, Liou JP(劉景平), Hwang-Verslues WW,
Pan SL(潘秀玲), HuangFu WC(黃甫維君)#. Frontiers in Pharmacology. 2018
Mar 13; 9: 205.【IF: 3.831 Ranking: 48/261】

Data Sources: Research Performance Index System

 Journal papers published-2018
γ-Glutamylcysteine synthetase (γ-GCS) as a target for overcoming chemo- and
radio-resistance of human hepatocellular carcinoma cells. Lin LC, Chen CF, Ho
CT, Liu JJ(劉俊仁), Liu TZ, Chern CL. Life Science. 2018 Apr 1; 198: 25-31.
【IF: 3.234 Ranking: 78/261】

Discovery of novel class IIa-selective histone deacetylase inhibitors using an in

silico virtual screening approach. Hsu KC, Liu CY, Lin TE, Hsieh JH, Sung TY,
Tseng HJ, Yang JM, Huang WJ(黃偉展)#. Scientific Reports. 2017 Jun 12; 7(1):
3228.【IF: 4.122 Ranking: 12/64】

Haloperidol Abrogates Matrix Metalloproteinase-9 Expression by Inhibition of

NF-kappa B Activation in Stimulated Human Monocytic Cells. Lee YL, Hsiao
CJ, Lin FL, Jan JS, Chou YC, Lin YY, Chen CK, Lam KK, Hsiao G(蕭哲志)#.
Mediators Of Inflammation. 2018 Apr 12; 2018: 9541459. 【IF: 3.549 Ranking:
61/155】

Data Sources: Research Performance Index System

 Journal papers published-2018
Expression and Regulation of Thymic Stromal Lymphopoietin and Thymic
Stromal Lymphopoietin Receptor Heterocomplex in the Innate-Adaptive
Immunity of Pediatric Asthma. Lin SC, Cheng FY, Liu JJ(劉俊仁), Ye YL.
Scientific Reports. 2018 Apr 18; 19(4).【IF: 4.122; Ranking: 12/64】

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and

HDAC. Ojha R, Huang HL, HuangFu WC, Wu YW, Nepali K, Lai MJ, Su CJ,
Sung TY, Chen YL, Pan SL(潘秀玲), Liou JP(劉景平)#. European Journal of
Medicinal Chemistry. 2018 Apr 25;150:667-677.【IF: 4.816 Ranking: 4/59】

The role of sentrin-specific protease 2 substrate recognition in TGF-beta-induced

tumorigenesis. Chang CC(張哲菖), Huang YS, Lin YM, Lin CJ, Jeng JC, Liu
SM, Ho TL, Chang RT, Changou CA, Ho CC, Shih HM. Scientific Reports. 2018
Apr 18; 19(4).【IF: 4.122 Ranking: 12/64】

Data Sources: Research Performance Index System

 Journal papers published-2018
Improvement of hyperglycemia in a murine model of insulin resistance and high
glucose- and inflammasome-mediated IL-1 beta expressions in macrophages by
silymarin. Lu CP, Huang CY, Wang SH, Chiu CH, Li LH, Hua KF, Wu TH(吳姿
樺)#. Chemico-biological Interactions. 2018 Jun 25; 290: 12-18.【IF: 3.296
Ranking: 75/261】

Design of Diarylheptanoid Derivatives as Dual Inhibitors Against Class IIa Histone

Deacetylase and beta-amyloid Aggregation. Chen LC, Tseng HJ, Liu CY, Huang YY,
Yen CC, Weng JR, Lu YL, Hou WC, Lin TE, Pan IH, Huang KK, Huang WJ(黃偉
展)#, Hsu KC#. Frontiers in Pharmacology. 2018 Jul 3; 9: 708.【IF: 3.831
Ranking: 48/261】

Effectiveness and Safety of Standard- and Low-Dose Rivaroxaban in Asians With

Atrial Fibrillation. Lin YC, Chien SC, Hsieh YC(謝宜蓁), Shih CM, Lin FY, Tsao
NW, Chen CW, Kao YT, Chiang KH, Chen WT, Chien LN, Huang CY. Journal Of
The American College Of Cardiology. 2018 Jul 31; 72(5): 477-485.【IF: 16.834
Ranking: 3/128】

Data Sources: Research Performance Index System

 Journal papers published-2018
Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-
Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor
Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis. Lin YC, Liu CY,
Kannagi R, Yang RB (楊瑞彬)#. Arteriosclerosis Thrombosis And Vascular
Biology. 2018 May; 38(5): 1202-1215.【IF: 6.086 Ranking: 5/65】

Losses of cytokines and chemokines are common genetic features of human

cancers: the somatic copy number alterations are correlated with patient
prognoses and therapeutic resistance. Wong HS, Chang WC( 張 偉 嶠 )#.
Oncoimmunology. 2018 Jul 30; 7(9): e1468951.【IF: 5.503 Ranking: 42/223】

Hypermethylation of CCND2 in Lung and Breast Cancer Is a Potential

Biomarker and Drug Target. Hung CS, Wang SC, Yen YT, Lee TH, Wen WC,
Lin RK(林若凱)#. International Journal Of Molecular Sciences. 2018 Oct 10;
19(10). 【IF: 3.687 Ranking: 90/293】

Data Sources: Research Performance Index System

 Journal papers published-2018
Novel Protective Effects of Cistanche Tubulosa Extract Against Low-
Luminance Blue Light-Induced Degenerative Retinopathy. Wu MR, Lin CH, Ho JD,
Hsiao G#, Cheng YW(鄭幼文)#. Cellular Physiology And Biochemistry. 2018; 51(1):
63-79. 【IF: 5.500 Ranking: 8/83】

A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions. Lin

TE, HuangFu WC(黃甫維君), Chao MW, Sung TY, Chang CD, Chen YY, Hsieh JH,
Tu HJ, Huang HL, Pan SL(潘秀玲), Hsu KC#. Frontiers in Pharmacology. 2018 Dec
4; 9: 1379.【IF: 3.831 Ranking: 48/261】

Development of a highly sensitive enzyme-linked immunosorbent assay (ELISA)

through use of polyprotein G-expressing cell-based microplates. Chen YJ, Chen M,
Hsieh YC, Su YC, Wang CH, Cheng CM, Kao AP, Wang KH, Cheng JJ, Chuang
KH(莊國祥)#. Scientific Reports. 2018 Dec 14; 8(1): 17868.【IF: 4.122 Ranking:
12/64】

Data Sources: Research Performance Index System

 Journal papers published-2018
Distributed and Side-pumped Fiber Laser Using a Laser Diode Bar Stack. LeeYW,
Huangfu WC(黃甫維君), Li YY, Wu IC, Huang SL, Liaw SKP, Dubinskii M. IEEE
ACCESS. 2018; 6: 70456-70462.【IF: 4.098 Ranking: 19/88】

Integrative genomic analysis for the functional roles of ITPKC in bone mineral density.
Lu HF, Wong HS, Chen BK, Liao HT, Hsu YW, Ikegawa S, Cho EC, Hung KS, (張偉
嶠)#. Bioscience Reports. 2018 Nov 30; 38(6).【IF:2.899 Ranking: 149/293】

Melanogenesis Inhibitors from the Rhizoma of Ligusticum Sinense in B16-F10

Melanoma Cells In Vitro and Zebrafish In Vivo. Cheng MC, Lee TH, Chu YT, Syu
LL, Hsu SJ, Cheng CH, Wu J, Lee CK(李慶國)#. International Journal Of
Molecular Sciences. 2018 Dec 11; 19(12). 【IF: 3.687 Ranking: 90/293】

Data Sources: Research Performance Index System

 Journal papers published-2019
Structure-guided design of anti-cancer ribonucleotide reductase inhibitors. Misko TA,
Liu YT, Harris ME, Oleinick NL, Pink J, Lee HY(李學耘), Dealwis CG. Journal Of
Enzyme Inhibition And Medicinal Chemistry. 2019 Jan; 34(1): 438-450).【IF: 4.027
Ranking: 10/61】

Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease. Chao HW,
Chao SW, Lin H (林恒), Ku HC, Cheng CF. International Journal Of Molecular
Sciences. 2019 Jan; 20(2): 298.【IF: 4.183 Ranking: 78/298】

SCUBEI-enhanced bone morphogenetic protein signaling protects against renal

ischemia-reperfusion injury. Liao WJ, Lin H(林恒), Cheng CF, Ka SM, Chen A,
Yang RB (楊瑞彬)#. Biochimica Et Biophysica Acta-molecular Basis Of Disease.
2019 Feb 1; 1865(2): 329-338. 【IF: 4.328 Ranking: 13/72】

Data Sources: Research Performance Index System

 Journal papers published-2019
Electrospun Polylactic Acid (PLLA) Microtube Array Membrane (MTAM)-An
Advanced Substrate for Anticancer Drug Screening. Tseng CH, Huang WT, Chew
CH, Lai JK, Tu SH, Wei PL, Lee KY, Lai GM, Chen CC (陳建中)#. Materials. 2019
Feb 14; 12(4).【IF: 2.972 Ranking: 102/293】

Enhanced Repeated-Batch Bioethanol Fermentation of Red Seaweeds Hydrolysates

Using Microtube Array Membrane-Encapsulated Yeast. Chen CC (陳建中), Lin HJ,
Lu WJ, Wu JJ, Chew CH, Wong CH, Yang CY, Lin HTV. Journal of Biobased
Materials and Bioenergy. 2019 Feb; 14(1): 138-145.

MPT0G413, A Novel HDAC6-Selective Inhibitor, and Bortezomib Synergistically

Exert Anti-tumor Activity in Multiple Myeloma Cells. Huang FI, Wu YW, Sung TY,
Liou JP, Lin MH, Pan SL (潘秀玲), Yang CR. Frontiers in Oncology. 2019; 9: 249.
【IF: 4.137 Ranking: 70/229】

Data Sources: Research Performance Index System

 Journal papers published-2019
In Vitro and In Vivo Studies of Hydrophilic Electrospun PLA95/-TCP Membranes for
Guided Tissue Regeneration (GTR) Applications. Chen CC (陳建中), Lee SY, Teng
NC, Hu HT, Huang PC, Yang JC. Nanomaterials. 2019 Apr 11; 9(4). 【IF: 4.034
Ranking: 71/293】

Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical
neurons. Lin HC, Ching YH, Huang CC, Pao PC, Lee YH, Chang WC, Kao TJ, Lee
YC (李宜釗)#. Journal Of Biomedical Science. 2019 Apr 26, 26: 30. 【IF: 5.203
Ranking: 70/229】

E2f1 regulates the induction of promyelocytic leukemia zinc finger transcription in

neuronal differentiation of pluripotent P19 embryonal carcinoma cells. Lin HC, Ko
CY, Lee KH, Chen IH, Kao TJ, Chang WC, Hsu TI, Lee YC ( 李 宜釗 )#.
Biochemical And Biophysical Research Communications. 2019 May 7; 512(3):
629-634. 【IF: 2.705 Ranking: 157/298】

Data Sources: Research Performance Index System

 Journal papers published-2019
Potential Effects of CXCL9 and CCL20 on Cardiac Fibrosis in Patients with
Myocardial Infarction and Isoproterenol-Treated Rats. Lin CF, Su CJ , Liu JH , Chen
ST, Huang HL, Pan SL(潘秀玲)#. Journal Of Clinical Medicine. 2019 May 11; 8(5).
【IF: 5.688 Ranking: 15/160】

Combination treatment strategy for pancreatic cancer involving the novel HDAC
inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status. Chao MW, Chang
LH, Tu HJ, Chang CD, Lai MJ, Chen YY, Liou JP(劉景平), Teng CM, Pan SL(潘秀
玲)#. Clinical Epigenetics. 2019 May 29; 11(1): 85. 【IF: 5.496 Ranking: 43/229】

Anti-metastatic activity of MPTOG211, a novel HDAC6 inhibitor, in human breast

cancer cells in vitro and in vivo. Hsieh YL, Tu HJ, Pan SL (潘秀玲), Liou JP, Yang
CR. Biochimica Et Biophysica Acta-molecular Cell Research. 2019 Jun; 1866(6):
992-1003. 【IF: 4.739 Ranking: 55/298】

Data Sources: Research Performance Index System

 Journal papers published-2019
Hirsutanol A Attenuates Lipopolysaccharide-Mediated Matrix Metalloproteinase 9
Expression and Cytokines Production and Improves Endotoxemia-Induced Acute
Sickness Behavior and Acute Lung Injury. Jan JS, Yang CH, Wang MH, Lin FL, Yen
JL, Hsieh I, Khotimchenko M, Lee TH, Hsiao G (蕭哲志)#. Marine Drugs. 2019
Jun 17; 17(6). pii: E360. 【IF: 3.722 Ranking: 15/61】

Simply Mixing Poly Protein G with Detection Antibodies Enhances the Detection
Limit and Sensitivity of Immunoassays. Chen YJ, Chen M, Cheng TL, Roffler SR,
Lin SY, Hsu HL, Wang CH, Chen CY, Kao AP, Cheng JJ, Chuang KH (莊國祥)#.
Analytical Chemistry. 2019 Jul 2; 91(13): 8310-8317. 【IF: 6.350 Ranking: 7/84】

NO2 functionalized coumarin derivatives suppress cancer progression and facilitate

apoptotic cell death in KRAS mutant colon cancer. Lin MH, Wang JS, Hsieh YC (謝
宜蓁), Zheng JH, Cho EC. Chemico-biological Interactions. 2019 Aug 25; 309:
108708. 【IF: 3.407 Ranking: 79/267】

Data Sources: Research Performance Index System

 Journal papers published-2019
TIMP3 expression associates with prognosis in colorectal cancer and its novel
arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and
angiogenesis. Huang HL, Liu YM, Sung TY, Huang TC, Cheng YW, Liou JP, Pan SL
(潘秀玲)#. Theranostics. 2019 Sep; 9: 6676-6689. 【IF: 8.063 Ranking: 10/163】

Adipocyte browning and resistance to obesity in mice is induced by expression of

ATF3. Cheng CF, Ku HC, Cheng JJ, Chao SW, Li HF, Lai PF, Chang CC (張哲
菖), Don MJ, Chen HH#, Lin H(林恒)#. Communications Biology . 2019 Oct 24;
2:389. 【IF: 3.407 Ranking: 79/267】

Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell

migration via PKCα-mediated AHR-HDAC interactions. Tsai CH, Li CH, Liao PL ,
Chang YW, Cheng YW (鄭幼文)#, Kang JJ#. Biochimica Et Biophysica Acta-
molecular Cell Research. 2019 Oct; 1867(2); 118-564. 【IF: 4.739 Ranking: 55/299】

Data Sources: Research Performance Index System

 Journal papers published-2019
Gene Expression Signature-Based Approach Identifies Antifungal Drug Ciclopirox As
a Novel Inhibitor of HMGA2 in Colorectal Cancer. Huang YM, Cheng CH, Pan SL
(潘秀玲), Yang PM, Lin DY, Lee KH. Biomolecules. 2019 Nov 2; 9(11), pii: E688.
【IF: 4.694 Ranking: 58/299】

Down-regulation of aryl hydrocarbon receptor intensifies carcinogen-induced retinal

lesion via SOCS3-STAT3 signaling. Tsai CH, Lee Y, Li CH, Cheng YW(鄭幼文)#,
Kang JJ#. Cell Biology And Toxicology. 2019 Nov 20. 【IF: 5.097 Ranking: 9/93】

Repeated-batch lactic acid fermentation using a novel bacterial immobilization

technique based on a microtube array membrane. Chen CC (陳建中), Lan CC, Pan
CL, Huang MY, Chew CH, Hung CC, Chen PH, Lin HTV. Process Biochemistry.
2019 Dec; 87: 25-32.【IF: 2.883 Ranking: 47/138】

Data Sources: Research Performance Index System

 Journal papers published-2020
Epidermal growth factor-like repeats of SCUBE1 derived from platelets are critical for
thrombus formation. Liao WJ, Wu MY, Peng CC, Tung YC, Yang RB (楊瑞彬)#.
Cardiovascular Research. 2020 Jan 1; 116(1):193-201. 【IF: 7.014 Ranking: 12/136】

Synthesis and Biological Evaluation of 2-quinolineacrylamides. Wang SW, Lin MH,

Hsu FC, Chen MC, Liou JP, Liu YT, Chen SS, Lee HY(李學耘)#. Bioorganic &
Medicinal Chemistry. 2020 Feb 1; 28(3): 115250. 【IF: 2.802 Ranking: 19/57】

Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer

cell migration via PKC alpha-mediated AHR-HDAC interactions. Tsai CH, Li CH,
Liao PL, Chang YW, Cheng YW(鄭幼文)#, Kang JJ#. Biochimica Et Biophysica
Acta-molecular Cell Research. 2020 Feb; 1867(2); 118564 【IF: 4.739 Ranking:
55/299】

Data Sources: Research Performance Index System

 Journal papers published-2020
Design, Synthesis, and Biological Evaluation of Heterotetracyclic Quinolinone
Derivatives as Anticancer Agents Targeting Topoisomerases. European Journal Of
Medicinal Chemistry. Lee JF, Chang TY, Liu ZF, Lee NZ, Yeh YH, Chen YS, Chen TC,
Chou HS, Li TK, Lee SB(李松柏)#, Lin MH#. European Journal Of Medicinal
Chemistry. 2020 Mar 15; 190: 112074. 【IF: 4.833 Ranking: 5/61】

Isoindoline Scaffold-Based Dual Inhibitors of HDAC6 and HSP90 Suppressing the

Growth of Lung Cancer in Vitro and in Vivo. Ojha R ,Nepali K, Chen CH, Chuang
KH, Wu TY, Lin TE, Hsu KC, Chao MW, Lai MJ, Lin MH, Huang HL, Chang CD,
Pan SL(潘秀玲), Chen MC#, Liou JP(劉景平)#. European Journal Of Medicinal
Chemistry. 2020 Mar 15; 190: 112086. 【IF: 4.833 Ranking: 5/61】

Astragalus membranaceus-Derived Anti-Programmed Death-1 Monoclonal

Antibodies With Immunomodulatory Therapeutic Effects Against Tumors. Chang
FL, Tsai KC, Lin TY, Yang TW, Lo YN, Chen WC, Chang JH, Lu MK, Chiou CT,
Chen PH, Yen Y#, Pan SL(潘秀玲)#, Lee YC(李雨青)#. BioMed Research
International. 2020 Mar 3; 2020: 3415471. 【IF: 2.197 Ranking: 94/162】

Data Sources: Research Performance Index System

 Journal papers published-2020
Investigating the potential effects of selective histone deacetylase 6 inhibitor
ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury. Lin CF, Hsu
KC, HuangFu WC, Lin TE, Huang HL#, Pan SL(潘秀玲)#. BMC Pharmacology and
Toxicology. 2020 Mar 12; 21(1): 21. 【IF: 2.103 Ranking: 172/267】

Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as

multitarget agents against Alzheimer‘s disease. Tseng HJ, Lin MH, Shiao YJ, Yang YC,
Chu JC, Chen CY, Chen YY, Lin TE, Su CJ, Pan SL (潘秀玲), Chen LC, Wang CY,
Hsu KC(許凱程)#, Huang WJ(黃偉展)#. European Journal Of Medicinal Chemistry.
2020 Apr 15; 192: 112193. 【IF: 4.833 Ranking: 5/61】

Benzenesulfonamide Derivatives as Calcium/Calmodulin-Dependent Protein Kinase

Inhibitors and Antiviral Agents against Dengue and Zika Virus Infections. Chen WC,
Simanjuntak Y, Chu LW, Ping YH, Lee YL, Lin YL, Li WS(李文山)#. European
Journal Of Medicinal Chemistry. 2020 Feb 13; 63(3): 1313-1327. 【IF: 4.833
Ranking: 5/61】

Data Sources: Research Performance Index System

 師資期刊論文發表-2020
Dicoumarol suppresses HMGA2-mediated oncogenic capacities and inhibits cell
proliferation by inducing apoptosis in colon cancer. Chen CH, Hsieh YC(謝宜蓁),
Yang PM, Liu YR, Cho EC. Biochemical And Biophysical Research
Communications. 2020 April 16; 524(4): 1003-1009.【IF: 2.985 Ranking:
159/297】

Association Between Anemia and Dementia: A Nationwide, Population-based

Cohort Study in Taiwan. Hong CT, Hsieh YC(謝宜蓁), Liu HY, Chiou HY, Chien
LN. Current Alzheimer Research. 2020; 17(2): 196-204. 【IF: 3.047 Ranking:
79/204】

Antiangiogenic Effect of isomalyngamide A Riboside CY01 in Breast Cancer Cells

via Inhibition of Migration, Tube Formation and pVEGFR2/pAKT Signals. Shih
CY, Chang TT, Chen CL, Li WS(李文山)#. Anti-Cancer Agents in Medicinal
Chemistry. 2020; 20(3): 386-399. 【IF: 2.049 Ranking: 43/61】

Data Sources: Research Performance Index System

 師資期刊論文發表-2020
Purine/purine isoster based scaffolds as new derivatives of benzamide class of
HDAC inhibitors. Nepali K, Chang TY, Lai MJ, Hsu KC, Lin TE, Lee SB(李松柏),
Liou JP(劉景平)#. European Journal Of Medicinal Chemistry. 2020 Jun 15; 196:
112291. 【IF: 5.572 Ranking: 5/61】

Ultrahigh packing density next generation microtube array membrane: A novel

solution for absorption-based extracorporeal endotoxin removal device. Chew CH,
Cheng LW, Huang WT, Wu YM ,Lee CW, Wu MS, Chen CC(陳建中)#. Journal Of
Biomedical Materials Research Part B-applied Biomaterials. 2020 May 6. 【IF:
2.831 Ranking: 35/87】

Hyperglycemia-related FAS gene and hsa-let-7b-5p as markers of poor outcomes

for ischaemic stroke. Chi NF, Chiou HY, Chou SY, Hu CJ, Chen KY, Chang CF,
Hsieh YC(謝宜蓁)#. European Journal Of Neurology. 2020 Apr 30. 【IF: 4.516
Ranking: 37/204】

Data Sources: Research Performance Index System