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GRAM – VE COCCI

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Neisseria SPP

-Gram –Ve diplococci .

-Aerobic.

-acid produce by oxidation ofcarbohydrates.

-Neisseria spp not lactose fermentation.

-None motile, None spores.

-Oxidase +Ve
.
-optimal growth at 35-37C.

-poor survival at cool temperature.

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Neisseria gonorrhoeae
* Gr-ve diplococci(Kidney-shaped).

*Non sporing , Non motile cocci

Characteristics
*Usually non capsulate.

*Aerobic
*Fastidious(need complex media for growth.
Require cystine for growth.
* Obligate parasite of human urogenital tract.
Habitat
*Dies quickly outside human host but may remain viable
in pus for some times
* Sexual contact. .
Transmission *Direct contact. .

* IgAase =Splits IgA(important in mucosal infections)

Pathogenesis *Pili=Attachment to mucous tissues

*LPS=Damages mucosal cells (lyposacchride)

* Gonorrhoea

*Pelvic Inflammatory Disease

Diseases
*Urethritis

*Infant Eye Infection (Ophthalmia Neonatorum)

*Gr-ve diplococci (Kidney-shaped)

Laboratory * Oxidase+Ve
Identification *Catalase +Ve

‫ﻻ ﺗﻨﺴﻮﻧﺎ ﻣﻦ ﺻﺎﻟﺢ دﻋﺎﺋﻜﻢ ﻓﻲ ﻇﮭﺮ اﻟﻐﯿﺐ‬ ‫ﻣﻠﺨﺺ ﻣﺎﯾﻜﺮو‬

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Neisseria meningitidis

*Gr-Ve diplococci (kidney-shaped).

* Non Sporing , Non Motile Cocci
Characteristics *capsulate cocci.
* Facultative anaerobic .
*has variable growth on nutrient agar.
*Human nasopharynx(10-25%).
Habitat *Dies quickly outside human host at room temp.

*Droplet spread.
Transmission
* IgAase =Splits IgA(important in mucosal infections)

*Pili=Attachment to mucous tissues

Pathogenesis
*LPS=Damages mucosal cells (lyposacchride)
*capsule=Antiphagocytosis

Diseases
 Meningitis(85% mortality rate when untreated)
 Bacteremia.

*Gr-Ve diplococci(kidney-shaped) in CSF.

Laboratory *Oxidase +Ve.
Identification
*Catalase +Ve
*oxidase glucose +maltose.

‫ﻻ ﺗﻨﺴﻮﻧﺎ ﻣﻦ ﺻﺎﻟﺢ دﻋﺎﺋﻜﻢ ﻓﻲ ﻇﮭﺮ اﻟﻐﯿﺐ‬ ‫ﻣﻠﺨﺺ ﻣﺎﯾﻜﺮو‬

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‫ﺗﻢ ﺑﺤﻤﺪ اﷲ وﻓﻀﻠﮫ وﻣﻨﺘﮫ ﻋﻠﯿﻨﺎ‬

‫اﻻﻧﺘﮭﺎء ﻣﻦ ﻣﻠﺨﺺ ﻋﻦ‬
‫‪GRAM –VE COCCI‬‬
‫وﺗﻢ اﻻﻋﺘﻤﺎد ﻋﻠﻰ ﻣﺮاﺟﻊ ﻣﻌﺘﻤﺪة‬
‫وﻣﻠﺨﺼﺎت وﻣﺬﻛﺮات ﺧﺎرﺟﯿﺔ‬

‫اﻟﻤﺮﺟﻊ اﻟﺬي ﺗﻢ اﻻﻋﺘﻤﺎد ﻋﻠﯿﮫ‬

‫اﻋﺘﻤﺎد ﻛﻠﻲ ھﻮ‬

‫‪Medical Microbiology‬‬
‫ﻟﻠﻤﺆﻟﻒ ‪Patrick Murray‬‬

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‫اﻟﻐﯿﺐ ‪ ..‬ﺑﺎﻟﺘﻮﻓﯿﻖ ﻓﻲ اﻟﺪﻧﯿﺎ واﻵﺧﺮة‬
‫وﺗﻘﺒﻠﻮا ﺷﻜﺮﻧﺎ وﺗﻘﺪﯾﺮﻧﺎ‬

‫ﻻ ﺗﻨﺴﻮﻧﺎ ﻣﻦ ﺻﺎﻟﺢ دﻋﺎﺋﻜﻢ ﻓﻲ ﻇﮭﺮ اﻟﻐﯿﺐ‬ ‫ﻣﻠﺨﺺ ﻣﺎﯾﻜﺮو‬

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