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New Scientist - May 23, 2020 USA PDF
New Scientist - May 23, 2020 USA PDF
YOUR
INTELLIGENT
APPETITE
The hidden laws of hunger
and how to make them work for you
Prime Minister Jacinda Ardern with 2019 Ryman Prize winner Dr Michael Fehlings.
www.rymanprize.com
This week’s issue
News Features
12 Chance encounter 30 Your intelligent appetite
Spacecraft set for a cosmic News Your body knows what you need
stroke of luck with a comet to eat. All you have to do is listen
Views
The back pages
21 The columnist
Chanda Prescod-Weinstein 53 Puzzles
on the physics of blue jays Quick crossword and the quiz
24 Culture 54 Cartoons
In The Vast of Night, teens The lighter side of life with
investigate a mysterious signal Tom Gauld and Twisteddoodles
25 Culture 55 Feedback
In Telling Lies, you don’t know Sanitiser moonshine; maths on
what to do, but that’s fun the cheap: the week in weird
Virtual events
Virtual event
Alien oceans on
Earth and beyond
Join NASA astrobiologist
Kevin Hand for a fascinating
online lecture exploring the best
chances of finding life beyond
Earth, at 6pm BST on 4 June. Dear reader,
NASA/JPL-CALTECH/SETI INSTITUTE
newscientist.com/events On 7 January, New Scientist
reported for the first time on a
mystery disease in Wuhan, China.
Podcasts On 1 February, the virus responsible
appeared on our front cover for
Weekly the first time. “How bad is it likely
The hunt for a fifth force of nature, to get?” we asked. The answer, of
a mouse-human chimera and using Alien oceans Discover the best spots for extraterrestrial life on 4 June course, turned out to be very bad.
seaweed to fight climate change. As New Scientist went to press
Plus swifts and robot dogs. this week, confirmed global cases
newscientist.com/podcasts Podcast of covid-19 stood at 4,834,449,
with 319,031 official deaths – and
that is with much of the world in
lockdown, our skies almost empty
Newsletter of planes. As lockdown measures
start to lift, there will be resurgences
Health Check
of the disease (see page 8). No one
Our free newsletter brings you a should bet on anything like the old
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IF YOU feel like your diet has completely including humans, appear to actually are the quintessential lockdown
gone to pot during lockdown, you have five separate appetites that work foods: ready meals, savoury snacks
probably aren’t alone. Stress and together to calibrate an individual’s and ice cream.
boredom are known risk factors for food intake (see page 30). These foods have long been blamed
overeating, and there is emerging That set-up works in natural food for diet-related diseases, and they are
evidence that many people, in the environments, but many people stopped guilty as charged. Yet not for the reasons
UK at least, are struggling to resist the living in such an environment decades we assume. Ultraprocessed foods tend to
comforts of food. Medical authorities be high in fats and sugar, but while they
are already worried about a parallel “Ultraprocessed foods are are low in protein, they tend to taste as
pandemic of mental illness. Maybe quintessential lockdown if they are high in protein. This subtlety
they should add weight gain to the list. fare: ready meals, savoury has crashed our five-appetite system
An unhealthy diet is often blamed snacks and ice cream” and is why our instinct to eat the correct
on poor choices and a lack of willpower. amount of protein may now be leading
These can play a part, but new research ago. “Ultraprocessed foods” made us to gorge on junk.
on appetite tells us that they are far from cheap fats and carbs – which It turns out that understanding
from the whole story. are pulverised, mixed with additives all your different appetites is crucial.
Appetite is conventionally viewed and then cooked up into finished Whether you choose to act on the
as a single, powerful drive to eat. products – now make up more than knowledge now or after the lockdown
But it isn’t so simple. Some animals, half of the typical Western diet and is, of course, up to you. ❚
There’s a whole
world out there...
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News Coronavirus
BY APRIL this year, around half of number of people each person with really burdened health system.” linked to nightclubs in Seoul. As a
the world’s population was under the virus is likely to infect. If this is The UK government reported result, some clubs and bars have
some kind of lockdown. Such above one, cases will continue to 2684 positive test results on 18 May. been ordered to close again.
restrictions helped slow the spread rise exponentially, so the aim is to Even when new case numbers There are concerns that similar
of the coronavirus. As new cases keep it below this. But that alone are low, lifting restrictions will outbreaks might occur in Germany,
decline in many places, countries are isn’t enough, says Pagel. always carry a risk of a second wave thanks to the gradual lifting of
beginning to ease restrictions. How “Say you have an R of just less than of infections. South Korea brought restrictions since the end of April.
can we know it is safe to do so? one. That will give you a stable level its outbreak under control with a Germany’s early response to the virus
The World Health Organization’s of infection,” says Pagel. “But if that stringent policy of testing, isolation and mass testing strategy brought
principal recommendation is that, in stable level of infection is thousands and contact tracing. In recent weeks, the country’s R down from more than
order to move to a sustainable level a day, that’s not really going to help the country was reporting only three to just below one during March.
of virus transmission, countries you – you’re going to end up with a around 10 new cases per day. But last week, between 407 and 927
should have the spread of the However, following eased restrictions new cases were reported every day,
virus under control. In practice, this Diners are distanced from 6 May, the Korea Centers for and estimates from the Robert Koch
means seeing a robust decline in in greenhouses at an Disease Control and Prevention last Institute in Berlin suggest that the R
the number of cases. Amsterdam restaurant week confirmed 102 new cases may have risen above one since 6 May.
The WHO also advises that In Wuhan, China, five new
countries use testing and contact cases of the virus were reported
tracing to identify and isolate new on 10 May, after the city where
cases of covid-19. Without screening the global outbreak started eased
and isolation, easing restrictions some restrictions in early April.
will inevitably lead to the number of However, other than a handful of
new infections rising again. When cases, there doesn’t appear to have
New Scientist went to press, the been a second wave of infections.
PACO NUNEZ/ANADOLU AGENCY VIA GETTY IMAGES
VENTILATION must be improved laden droplets from the indoor concentration falls off rapidly
in buildings and aeroplanes environment where they were with distance. Outdoors, people
to reduce the risk of covid-19 exhaled,” says Lidia Morawska are unlikely to breathe in enough
spreading via the air, according to at the Queensland University virus to infect them unless they
recommendations from several of Technology in Australia. remain close to an infected person
organisations, including the When infected people cough, for an extended period. Indoors,
European Union Aviation Safety sneeze, sing, talk or even breathe, the risk is much higher.
Agency. It is unclear if this advice they emit droplets containing the There is plenty of evidence that
is being followed. coronavirus into the air. The closer confined spaces pose a higher risk.
We know the coronavirus can you are to them, the more likely For instance, one person in South
spread via droplets in air, but these droplets are to end up in Korea infected 94 of the 216 people
your eyes, nose or mouth. This working on the same office floor.
CAVAN IMAGES/ALAMY
94
people on the same office floor
much everyone agrees on.
In January, 10 people from three
different groups became infected
However, to what extent airborne
spread contributes to such clusters
remains unclear.
were infected by one person after eating at a restaurant in A report from China attributes
Guangzhou, China. It is thought coronavirus infections among bus
there is still debate about the that the air flow from an air The risk of coronavirus passengers in Hunan province to
details and how much this form conditioner blew droplets from an infection seems greater airborne spread, with one person
of transmission contributes to the infected person to nearby tables. in confined spaces sitting 4.5 metres from someone
virus’s spread. What is clear is that And in March, one member of who infected them. It suggests
the risk is greatest if you spend a choir infected at least 32 of the person to put them on a ventilator. the virus can remain airborne
a long time in a confined, poorly 61 people at a practice in a small Linsey Marr at Virginia Tech for at least 30 minutes.
ventilated space with others who church in Washington state, says the virus-carrying droplets The UK’s Chartered Institution
might be infected – something according to a report by the US emitted by infected people range of Building Services Engineers
that many workers cannot avoid. Centers for Disease Control and from microscopic ones to those recommends using only outside
For this reason, scientists and Prevention. The choristers say large enough to be visible. But air if possible, rather than
safety experts think there should they used hand sanitiser and tried people emit thousands of times recirculating air within buildings,
be more emphasis on improving to maintain social distancing. more smaller droplets than large and says HEPA filters or ultraviolet
ventilation, in addition to The World Health Organization ones, and she thinks these smaller sterilisers could eliminate any
measures such as handwashing says airborne transmission via droplets are what infect people. airborne virus. The European
and social distancing. “The most small droplets is possible, but only Although microscopic droplets Union Aviation Safety Agency
significant measure is to increase when medical procedures generate can travel further in the air than issued similar recommendations
ventilation to remove the virus- aerosols, such as intubating a larger droplets, says Marr, their for aircraft operators. ❚
But many of the reports that that in places like Italy where there enough covid-19 infections to end in England to establish risk factors
find lower rates of smoking among weren’t always enough intensive up in hospital are older, and older linked with dying from covid-19
covid-19 patients also suggest that care beds to go round, some may people have lower smoking rates. among (medRxiv, doi.org/dt9z).
smoking is more common among have lied about smoking, he says. Rather than looking at smoking The results for smoking change
people who get sickest and die Perhaps the biggest concern is rates in hospital patients, Hopkinson depending on which other risk
(Qeios, doi.org/dv8j). This is hard that it isn’t valid to compare smoking is using an app downloaded by factors are included. But the
to explain if nicotine really protects rates among coronavirus patients 1.5 million people in the UK to track most logical analysis according
against the coronavirus. with the general population, says their cases. His findings aren’t yet to Hopkinson, adjusting for age
Questions have also been raised Eleanor Murray at Boston University. published, but suggest that smokers and sex only, finds smokers at a
about the accuracy of the initial Most people who have severe are about 25 per cent more likely somewhat higher risk of dying
reports. Some people recorded as to develop covid-19 symptoms – from covid-19. “The claim that
non-smokers may have recently “Unpublished findings although this is judged by users’ smoking is protective is interesting
stopped due to the pandemic, says suggest smokers may be self-reports, not medical tests. and perplexing, but it doesn’t
Nick Hopkinson at Imperial College 25 per cent more likely A recent study looked at the stand up to scrutiny,” he says. ❚
London. There has been speculation to develop covid-19” health records of 17 million people Clare Wilson
immune system.
your fruit and veg raw, it is recovery time, but it doesn’t seem effective against the coronavirus that, while bans might delay the
worth washing them. The to reduce the number of deaths. (Cochrane Database of Systematic arrival of a virus, they don’t stop
advice from the World Health A real game-changer would Reviews, doi.org/dv8v). What’s the spread in the long term.
Organization (WHO) is to “wash be a drug that helps people with more, one of the 32 people treated Travel bans have been
them the same way you would severe covid-19 recover. Instead in these studies developed implemented in several countries,
of targeting the virus, such a drug anaphylactic shock. and it is plausible that countries
“Properly cooking food will would need to help reverse the Even if serum therapy is will consider longer-term
kill off viruses. The WHO severe inflammatory response – effective, it is hard to scale up. measures, or wider use of testing
recommends washing called a cytokine storm – that it Several firms are starting to make and quarantine for any new
raw fruit and veg” triggers in some people. No such pure antibodies in factories, an arrivals. But there will always be
drug has been developed yet. approach that is likely to be safer. some travel between countries,
in any other circumstance”, Human trials of several vaccines says Hunter. “In a global society,
which means washing your have already begun. There is no You can take pills to cut your risk you can’t ban all movement in
hands before you handle them, guarantee that these efforts will of catching HIV – could something and out of a country,” he says.
and washing produce with succeed, but many vaccine similar be made against the “You’d starve to death.”
water before you eat it. researchers are optimistic. coronavirus?
For a few years, pre-exposure Will covid-19 always be with
Are toilets and sewage systems Could antibodies from recovered prophylaxis (PrEP) has been us or can it be eradicated?
an infection risk? patients be used as a treatment enabling higher-risk people to Countries such as China, South
It is possible, because people with for covid-19? cut their risk of contracting HIV. Korea and New Zealand are
covid-19 shed the virus in their This approach is already being There is currently an intense showing that it probably is
faeces. When Yuguo Li at the tested in about 20 randomised research effort to develop antiviral possible to eliminate the virus.
University of Hong Kong and his trials. The idea behind drugs that could treat covid-19 by This requires a lot of effort
colleagues analysed surface and convalescent plasma or serum stopping the coronavirus from though. China is trying to test
air samples taken from a hospital therapy, as it is known, is that it multiplying. If successful, these 11 million people in 10 days
treating people with covid-19, can take weeks for our bodies to antivirals could potentially be to prevent a second wave
the team found the most virus produce enough antibodies to used in a prevention strategy of infection in Wuhan.
in samples taken from toilets overcome a new virus. Injecting similar to HIV PrEP.
(medRxiv, doi.org/dv8t). severely ill people with antibodies However, to take a drug for “It probably is possible to
In 2003, the SARS virus is made by others who have recently preventive purposes, rather than eliminate the virus – but
thought to have spread through a recovered could help fight the as a treatment, we need to be as it requires resources and
housing block through plumbing virus in the meantime. sure as possible that it is safe, and political will”
and ventilation systems, but A 14 May review of the handful that is likely to take many years.
overall, the risk of getting the of small, non-randomised studies Because most people don’t get Many countries lack the
virus from toilets or sewage published so far concluded that it severely ill with covid-19, it is likely resources or political will to
is low, according to the WHO. was uncertain if this approach is that such a preventive drug would do this. The US and the UK, for
be given only to those thought example, are already looking at
What is more likely – a successful to be particularly vulnerable easing coronavirus restrictions
vaccine, or an effective drug? or at high risk of exposure. despite having large outbreaks
We are likely to see several drugs and insufficient systems for
approved for treating covid-19 Will countries that successfully testing and contact tracing. If
before any vaccine becomes contain the virus refuse visitors approaches like this continue, the
available, but they won’t be from countries that don’t? virus will become widespread and
miracle cures. It isn’t clear how travel bans come to be seen as less of a threat,
We will almost certainly find might slow the spread of disease. but only after many more deaths.
drugs that have statistically Only a handful of studies have A vaccine could be the answer
significant effects, but these estimated how such bans might to wiping the virus out, but as the
effects are likely to be modest. have affected the spread of WHO’s Michael Ryan noted at a
PAUL KANE/GETTY IMAGES
For instance, a drug called Ebola and SARS. These suggest press conference on 13 May, we
remdesivir has received have failed to eradicate diseases
emergency use approval in Flu vaccines help protect for which we do have vaccines,
the US based on initial results those most vulnerable or such as measles. “The virus may
suggesting that it shortens likely to catch influenza never go away,” he said. ❚
A RECENTLY launched spacecraft Solar Orbiter has a suite of soon as possible and last for as most likely be ready and able
may cross paths with a comet that instruments designed to study the many days as needed to cover to make measurements,” says
began disintegrating last month, sun, including those to take the the entire period of interest.” Zouganelis. “These are the
which could help us learn more first-ever images of its poles. Some The spacecraft is currently in magnetometer, the [radio] waves
about these icy objects. of these instruments could also a commissioning phase, testing instrument and the energetic
Geraint Jones at University examine the tails of comet ATLAS. out its different instruments, and particle detectors.” A fourth
College London and his colleagues The ESA was unaware of this this isn’t expected to be completed instrument, designed to study
have calculated that the Solar opportunity before the craft until 15 June – too late for the the solar wind, could also be
Orbiter spacecraft will pass behind launched, so is now looking rendezvous. But there is a chance fully tested in time.
comet C/2019 Y4 (ATLAS) at a into what can be achieved. “The some will be all set before that. The spacecraft could probe the
distance of about 30 million decision should be taken in the “Three of our instruments will structure of the comet’s ion tail
kilometres in a matter of weeks next days,” says Yannis Zouganelis, and see if a shock wave believed
(arxiv.org/abs/2005.03806). the deputy project scientist for the The blue-green comet to form as the comet’s head
The European Space Agency Solar Orbiter mission. “If positive, C/2019 Y4 (ATLAS), pushes through the solar wind
(ESA) probe, which was launched the measurements would start as captured by a telescope also passes behind it.
on 10 February, may pass through It could also measure the mass
the comet’s two long tails, allowing of grains in the dust tail, and could
it to perform unprecedented even detect pristine material
studies of debris from the object. emanating from the comet’s
“At the end of May, there’s a broken innards. “The ions would
chance that Solar Orbiter may be potentially coming from inside
cross the ion tail,” says Jones. “And the nucleus,” says Jones. It isn’t
then a few days later, on 6 June, thought that any of the material
it’ll cross the comet’s orbital plane, could damage the spacecraft.
and that’s where the dust tail is.” Whatever happens, Solar
The ion tail of a comet consists Orbiter looks set to become one of
of the electrically charged particles, just a handful of spacecraft to travel
or ions, pushed behind it for many through a comet’s tail. NASA and
millions of kilometres by charged the ESA’s Ulysses spacecraft, which
NASA/TIFFANY CLEMENTS
particles from the sun, the solar launched in 1990, passed through
wind. The dust tail, meanwhile, at least three comet tails. But these
comprises grains of dust that traverses went unnoticed until
have been dislodged from the after they occurred. “Now we know
comet and follow its orbit. what to look for,” says Jones. ❚
Pollution
We may have missed microplastic in the sea, people used holes collected 2.5 times of seawater (Environmental
traditional plankton nets,” says more microplastic than the Pollution, doi.org/dvvn).
half the microplastic Penelope Lindeque at Plymouth standard plankton nets. The That is far more than thought. An
in the ocean Marine Laboratory in the UK. These researchers extrapolated from influential 2015 study estimated
have holes about 333 micrometres their data to estimate how much there are 15 to 51 trillion particles
WE HAVE underestimated the across, so they don’t catch microplastic would be caught of microplastic in the ocean. “They
amount of microplastic in the ocean, fragments smaller than that. by a net with 1-micrometre holes. always admitted that that budget is
by a factor of 2.5 at least. Many of Lindeque and her colleagues Their calculations suggested very conservative,” says Lindeque,
the smallest pieces are thin fibres. trawled the ocean surface with there are 3700 pieces of because it was based on studies
Millions of tonnes of plastic waste three kinds of net with holes 500, microplastic in every cubic metre that used 333-micrometre nets.
enter the ocean every year. Much 333 and 100 micrometres wide. The real total could “easily” be
of this is tiny fragments, known as They repeated the study in two “Estimates suggest 10 times more, she says. These
microplastic, which are invisible widely separated regions: the Gulf there are 3700 pieces smaller fibres may come from
to the naked eye. of Maine and the English Channel. of microplastic in every fishing rope, textiles and clothes. ❚
“When we started looking for The nets with 100-micrometre cubic metre of seawater” Michael Marshall
Weekly podcast
Episode 17 out Friday 22 May
Our weekly podcast has become the must-listen science show, bringing you the
most important, surprising or just plain weird events and discoveries of the week.
If you missed the earlier episodes you can still listen in to hear about:
UNPRECEDENTED Arctic blazes usually re-emerge within melted, although there are A DEVICE inspired by fidget
blazes last year appear to have 50 days of snow melting, the reasons to suspect the former. spinner toys can diagnose a urinary
smouldered through winter report added. “The fires seem so widespread tract infection (UTI) in less than
below ground as “zombie fires” If more fires are surviving and so sudden that I find it hard an hour, without the need for a
only to reignite this month. winter, that is bad news for to believe that humans could laboratory or electricity.
Intense blazes across the climate change, says Smith. have been everywhere at once The device takes advantage of
frozen north in 2019 released “The implication is greater net in such a sparsely populated the centrifugal force generated by
record amounts of carbon – on carbon emissions, given that place,” he says. spinning to push the urine sample
a par with the annual emissions overwintering fires, by their Nonetheless, Anton through a membrane lining its
of Belgium – exacerbating the nature, are smouldering soil Beneslavskiy at Greenpeace interior. Any bacteria in the urine is
global warming that made the in Russia thinks intentional separated from the liquid and sticks
conditions for the fires possible “If the fires burn through burning by people is more likely to the surface of the membrane.
in the first place. long-term carbon stores, to be the cause in this region, Adding a dye that stains bacterial
Now, as temperatures rise in there may be greater net noting past surveys have shown cells orange then reveals their
the region and snow recedes, carbon emissions” most fires start near roads and presence within 45 minutes.
fires are erupting in Siberia logging sites. While he says “It is easy to operate,” says
again. Satellite analysis of last and peat fires, burning through zombie fires are possible, he Yoon-Kyoung Cho at the Ulsan
year’s burn sites and the fires long-term carbon stores.” adds: “There is no clear evidence National Institute of Science and
erupting this month suggest Mark Parrington at the they were the reason for the Technology in South Korea. One
many may be zombie fires. European Centre for Medium- fires of the last week.” or two spins is usually enough
“The satellite images are Range Weather Forecasts in One way to mitigate against to get a diagnosis, she says.
astonishing, particularly the the UK echoes the risk of a zombie fires is more monitoring Cho and her team tested the
snowmelt immediately knock-on effect. He says that on the ground so they can be device using urine samples from
followed by the fires appearing,” there may be a cumulative effect extinguished in winter, says 39 people who were suspected
says Thomas Smith at the of the previous fire season Jessica McCarty at Miami to have UTIs. The team found that
London School of Economics. feeding into the coming season University in Florida. “Most it gave similar results to the
In an analysis for New and leading to large-scale and zombie fires in Alaska have standard laboratory-based test,
Scientist based on imagery from long-term fires across the been caught because hunters which involves culturing bacteria
the European Space Agency’s region again. or snowmobilers report the and takes several days (Nature
Sentinel-2 satellites, Smith Without reports from the locations to the Alaska Forest Biomedical Engineering, DOI:
identified 2019 burn scars ground, Smith says we can’t Service. Without that in situ 10.1038/s41551-020-0557-2).
and 2020 hotspots. He found know for certain if the blazes in info, we would never find them, Because of the longer turn-around
overlap of fires from last July Siberia are zombie fires or new as they are often still partially time for the standard test, people
and fires that appeared ones lit by people as the snow covered in snow.” ❚ are often treated with antibiotics
immediately after snowmelt before being diagnosed, says Cho,
this year. This includes known which contributes to the rise of
CONTAINS MODIFIED COPERNICUS SENTINEL DATA [2019]/SENTINEL HUB/PIERRE MARKUSE
Mathematics
Virtual reality Here in the 21st century, These 3D shapes given number of dimensions, and
we have virtual reality to help. are actually slices used this formula as the basis for
lets you enter the Marc ten Bosch, a game designer of 4D objects the physics in his game. He will be
fourth dimension in California, has made a video game presenting the work at the virtual
called 4D Toys. This lets you use SIGGRAPH conference in July.
MARC TEN BOSCH
WE MAY not be able to step into virtual reality to move 4D shapes “It felt like a toy would be a
the fourth dimension of space, but such as hypercubes around a good showcase of this weird
a new look at the physics of objects 3D slice of a 4D space using a slider. physics so you could get a feel for
in many dimensions can help us To make the game, ten Bosch it by playing with shapes and not
understand what it would be like. first had to figure out how these idea that it can be solid and collide really worry too much about all
The 19th-century novella objects would move and interact with other shapes,” he says. the complexities,” says ten Bosch.
Flatland imagined how beings with one another. “Before, people He devised a mathematical “It could help you build an intuition
on a 2D plane might perceive were thinking about the abstract formula using geometric algebra for these concepts that are pretty
3D objects, but scaling that up concept of a 4D shape, but not and fluid dynamics to describe how inaccessible now.” ❚
into more dimensions isn’t intuitive. actually the world around it or the objects move around a space in any Leah Crane
Launchpad
Voyage across the galaxy and beyond
with our monthly space newsletter
JOSCHUA KNÜPPE
sight “see” the letters.
Daniel Yoshor at the University
of Pennsylvania and his colleagues
worked with five people who had
electrodes implanted on their Ancient anchovies
visual cortices. Two participants had fearsome teeth
had implants as part of a trial to
treat blindness, the other three Huge sabre-toothed
were able to see and had implants anchovies may have
as part of epilepsy treatment. evolved because the
When the team stimulated the asteroid thought to have
electrodes in sequence to trace the killed the dinosaurs also
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Views
Letters Culture Culture Aperture
Pluses and minuses In The Vast of Night, In Telling Lies, you don’t A green turtle
of a new take on teens investigate a know what to do, but that’s uses tube sponges
consciousness p22 mysterious signal p24 fun, says Jacob Aron p25 as a hammock p28
Columnist
H
Chanda Prescod-Weinstein ERE in New Hampshire, looks dark brown, and the loss As I have mentioned in earlier
is an assistant professor of I live next to a wooded of eumelanins is why increasingly columns, figuring out what’s
physics and astronomy, and area, and covid-19 means my hair strands look white. going on in the night sky is a bit
a core faculty member in that I have been spending a lot of Melanins, including red-yellow of a detective game. We can’t
women’s studies at the time at home. This has translated ones, are the same pigments make the sky in our lab, so we
University of New Hampshire. into me becoming a bit of a birder. that cause humans to have a have to get good at understanding
Her research in theoretical All day long, I text friends with diverse set of skin colours. what we are seeing and squeezing
physics focuses on cosmology, my sightings – a hawk walking on Melanin is also a source of information out of the light
neutron stars and particles the ground hunting smaller birds, pigments for bird feathers. The that arrives here on Earth.
beyond the standard model a female northern cardinal, a bird brown sparrows I see eating bugs One of the questions we ask
that I thought was a woodpecker on my lawn have feathers full when looking at an object like
but was actually a warbler. I enjoy of melanin. Those sparrows, another planet or a star is: what
all of the birds I see, but my just like us, look they way they is it made of? One of the best ways
favourite visitors are the blue jays. do because of these pigments. to tell is by doing spectroscopy:
They have such a beautiful pattern looking at the spectrum of light
Chanda’s week of bright blue, black and white, “Blue jays are flying coming from the object.
What I’m reading and they are fast movers too. diffraction gratings, Based on lab experiments
Now seems like either an Being the physicist that I am, on Earth, we know which
highly evolved, natural
excellent or terrible time I haven’t just enjoyed the birds colours of light match with the
to read Octavia E. Butler’s but have also been reading up instruments of light presence of different chemical
Parable of the Sower. on the science behind their manipulation” elements. For example, light
colours. And here is the thing with a wavelength of 589
What I’m watching I learned: the blue jay’s beautiful The blue jay, on the other nanometres – orange – is sodium.
I recently finished blue shades aren’t real, they hand, has a feather that has What has this got to do with
The Schouwendam 12, aren’t blue like my jeans are blue. a special microstructure, and bird feathers? The instruments
and I was very surprised Not only is this shocking that microstructure mimics the that we use to look at this aspect
by the ending. revelation true, but the blue jay photochemical reaction through of astrophysical sources,
isn’t special either. It is common a process called diffraction. This spectrographs, rely on a tool
What I’m working on for “blue” bird feathers to appear phenomenon is what occurs called a diffraction grating,
I have two postgraduate to be blue, without actually when light runs into a barrier, which uses the phenomenon of
students writing up having any blue colour in them. bends and has a tendency to diffraction to break the light up.
their first papers on Reading this felt like saying that spread out. In some sense, then, the blue
dark matter. Exciting! my hair isn’t actually dark brown, In the case of birds, at the jays I have been watching are
it just looks that way. In fact, my microscopic level, some feathers not just interesting birds of the
hair looks the way it does thanks are structured so that even corvidae family, distant cousins
to melanin pigments, chemicals though they are brown, when of the highly intelligent crow.
that absorb some parts of the light interacts with them, only They are also flying diffraction
light spectrum and reflect others. the blue parts of the light are gratings, highly evolved,
Some of these, eumelanins, reflected away to observers. natural instruments of light
absorb light that doesn’t look Reading about this as a physicist manipulation.
This column appears brown or black and reflect back the was pretty surprising because Understanding this, I am
monthly. Up next week: parts that do. This photochemical diffraction plays an important now even more in awe of
Graham Lawton reaction is why most of my hair role in astronomy. them than I was before. ❚
you could ascribe to any of its consciousness. If I may be so bold Going cold on a new
Editor’s pick component parts. as to propose a subject for a future definition of life
This appears to exclude what article in the same vein: how Letters, 25 April
Pluses and minuses of new
would seem an interesting and about asking if electrons have free From James Veale, Cambridge, UK
take on consciousness useful area for such research: the will? That might shed new light on Hillary Shaw suggests a definition
2 May, p40 emergence of consciousness-like quantum weirdness. of what constitutes life. It is
From Guy Inchbald, behaviours in flocks of starlings, defined as “a bounded system
Upton on Severn, Worcestershire, UK the coordination of a beehive’s containing a readable information
Lockdown could give
Integrated information theory activities or the general behaviour code that can locally decrease
(IIT), identified in your article as the of crowds. us many insights entropy”. This seemed to me to
best bet for a mathematical model However, perhaps IIT has From Steve Dalton, succinctly encapsulate all forms
of consciousness, may not point a bigger problem with its Chipstead, Kent, UK of life that we know about, and
towards panpsychism, the universal definitions, if it yields the It is clear that our understanding reduced a complicated concept to
consciousness of matter, as same degree of what it calls of the coronavirus, and how it a simple idea in a really satisfying
suggested. This is for the simple consciousness whether someone spreads through networks of way – I liked it a lot.
reason that it points clearly towards is conscious or unconscious. people, is related to the quantity Then, two weeks later, I opened
something else entirely. The way and quality of data we collect. my fridge and realised that it, too,
that IIT focuses on information From Nicholas Humphrey, This is rightly a point of focus. decreases entropy locally and
may not be its greatest weakness, Theoretical psychologist known But it would be a great shame contains readable (binary)
but its greatest insight. for his work on the evolution of if, while focusing on covid-19, we information that tells its “body”
As far as IIT is concerned, it isn’t consciousness, Cambridge, UK missed the opportunity to gather how to do it – how annoying!
the brain that is conscious, but the With consciousness, it seems that detailed information on the Can we extend the definition
information flowing through it. anything goes: no need to define spread of other communicable to exclude systems that were
A close, if not perfect, parallel may terms or respect hard-fought-for diseases during lockdown, not created by other readable
be drawn with the meaning of this philosophical distinctions. to mention non-health aspects of information-encoded, entropy-
letter being a property not of my I disagree with the idea that life. That data could yield never-to- decreasing systems?
computer, but of the information integrated information theory is be-seen-again insights. Perhaps we could, but while
that flowed through it. We may “our mathematically most mature such an extension would rule
simply have been looking for the theory of consciousness”. It isn’t out fridges, I assume it would also
Sunshine may not be
origin of consciousness at the a theory of consciousness, it is a exclude babies and genetically
wrong level of neural activity. theory of integrated information. Australia’s saving grace modified organisms. I fear I may
If this is so, then electrons remain It may conceivably have a bearing Letters, 2 May be back to square one.
as devoid of consciousness as ever. on intelligence, but it has nothing From Shaun McCree,
Instead, we should be looking at the to say about the quality of Seaford Meadows, South Australia
Every dog may
information encoded in the patterns consciously felt sensory Diana George asks whether the
of activity of those electrons. experience. That is the hard increased uptake of vitamin D in not have its day
problem of consciousness: to Australia has resulted in our low 25 April, p36
From Will McNeill, explain what it is like for creatures infection rates from coronavirus. From Graeme Armstrong, Broken
Southampton, Hampshire, UK such as us to feel the pain of a bee I’d say no, for two reasons. Hill, New South Wales, Australia
As a model to inform our sting or see the redness of a poppy. Firstly, most Australians avoid As the National Parks and Wildlife
understanding of consciousness, Mathematics shows no sign the sun because of the heat and its Service threatened species officer
integrated information theory of being unreasonably – or even cancer-causing effects. Secondly, in Broken Hill, Sturt national park
sounds promising. Yet usually reasonably – effective here. I’ll the lack of cases here probably has is in my patch. The idea you
when a theory produces a continue to put my money on more to do with a fairly quick and reported of fencing the park as
conclusion that seems absurd – neuroscience and evolutionary severe lockdown that cut the an experimental plot for dingo
in this case that both the universe psychology for answers. country off from most overseas introduction is of interest to me.
and simple data processing arrivals. Most of our cases are The claims that dingoes
algorithms are conscious – the From Rod Munday, linked to several cruise liners have a positive effect on small
sensible working hypothesis is Cardiff, UK and aircraft that arrived before mammal survival, and the desire
to suppose it is false. It was kind of you to lift some of the closure was fully in place. to test this by fencing the park,
the covid-19 gloom by publishing By all means get some fail to see the obvious: that this
From Andy Howe, a whimsical article suggesting sunshine, but I don’t think experiment has been going on
Sheffield, South Yorkshire, UK inanimate objects could possess it will help that much. for over 100 years either side of
It seems a shame for the proposed the dog fence that protects south-
integrated information theory eastern Australia. Small mammals
(IIT) model of consciousness to Want to get in touch? have suffered equally on both
stipulate that for something to Send letters to letters@newscientist.com; sides. The higher density of
be considered conscious this way, see terms at newscientist.com/letters dingoes north of the fence hasn’t
its consciousness has to be bigger Letters sent to New Scientist, 25 Bedford Street, resulted in better outcomes for
than the degree of consciousness London WC2E 9ES will be delayed small mammals. ❚
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Views Culture
T-B: KILIII YUYAN/BRITISH MUSEUM; AGENTS OF SHIELD - ABC MATTHIAS CLAMER; UNIVERSITY OF CHICAGO PRESS
computer, and you take control database contains both sides of of little windows on the world. ❚
of the desktop. In a nice touch,
her reflection on the screen remains
partially visible throughout, a mirror
of your voyeuristic self. You can
even play a game of solitaire.
On the computer, there is a
database of videos, apparently
stolen from the US National Security
Agency. You can search them for Read
particular words, but only the first The Science of Walking
five results are watchable – there is all about how there is
is a slightly hokey in-game reason more to taking a stroll
for this limitation – which forces than meets the eye.
you to tease out clues. The clips Physiology, neurology,
are all shot with real actors on anthropology and
ANNAPURNA INTERACTIVE
Accelerating
the cultured
meat revolution
“It will be made in a similar way to brewing significantly increasing the pressure on into products such as burgers patties,
beer,” says Lavanya Anandan. She is not limited resources such as land and water. sausages or shrimp mince.
talking about a new kind of drink, however, This in turn will drive climate change. Today, Currently, around 50 start-ups around the
but describing a new industry aiming to livestock farming is responsible for 15 per world are developing and improving the
grow meat in the lab. This new food is cent of global greenhouse gas emissions cultured meat process to make different
known as clean meat, cultured meat or and is a key cause of deforestation. “If you meats and seafood. Each is growing its own
cultivated meat. look at the numbers, they’re quite special cells that require bespoke growth
Demand for meat has never been higher, staggering,” says Anandan. media and cellular scaffolding. And they are
but the way we produce it today is If meat could be grown in the lab instead all looking to scale up production while
unsustainable and, for some, ethically of on farms, it could create an alternative to bringing down costs.
dubious. So scientists around the world are traditionally-produced meat and help This is where the expertise of Merck
learning to grow meat and seafood in their reduce the environmental footprint for KGaA, Darmstadt, Germany, comes in.
labs without the need for farms or livestock. meat production. Additionally, by reducing “The techniques used to culture meat are
They have had considerable success — or eliminating the use of antibiotics and the same for the biologics and cell therapy
the world’s first lab-grown beef burger was hormones, cultured meat could also have industry and, as a leading life sciences
cooked and tasted in London in 2013, albeit positive health aspects. company, we’ve helped solve similar
at a price of around $250,000 and costs have Cultured meat is produced using some of challenges,” says Anandan.
dropped by orders of magnitude since. The the same technologies biologists have used The company is not aiming to grow its
challenge now is to turn these lab-based own meat but to develop the materials and
successes into food that can be sold on “As a life sciences technologies that will accelerate its
supermarket shelves at reasonable prices. development. And it is already working
That’s how Anandan fits in. Leading a
company, we’ve helped with start-ups, non-profits and academics.
new Innovation Field on this topic and solve similar challenges” “We are taking our existing expertise and
based in Silicon Valley, Anandan works for trying to come up with innovative solutions
Merck KGaA, Darmstadt, Germany, a for decades to grow animal cells. First, and technologies — such as reagents and
leading science and technology company muscle cells are taken from live animals as a analytical tools — to solve problems for the
in Healthcare, Life Science and small biopsy from which stem cells are clean meat sector,” she says.
Performance Materials with a 350-year isolated and then cultured in the lab. One important goal is to find the right
record of innovation. The company’s The next stage is more difficult, however. formulation for the growth media. This is a
strategy and transformation team is The cultured cells must then be grown and cocktail of 50 to 100 ingredients such as
working on new products and technologies differentiated into a form of tissue sugars, salts, amino acids, micronutrients
for the future. One of their goals is to comprising of muscle, fat and other cells and growth factor. “Each cell line is going to
provide the technology platforms and that is suitable for food processing and require a specific optimised formula,” says
infrastructure that will enable the cultured consumption. This takes place inside Anandan.
meat revolution. bioreactors where the cells are trapped and This growth medium must also not
This revolution is desperately needed. supported in a scaffold of fibres, just as in contain animal-derived compounds and
The world’s population is growing, with animal tissue, and submerged in a cocktail economical enough to make lab-grown
another 2 billion expected by 2050. Demand of nutrients called a growth media. Finally, meat affordable. “Cost is an important
for meat is expected to grow by 70 per cent, this tissue must be processed and formed hurdle that has to be overcome,” she says.
Ideas Factories
What if medicines could be
3D printed? Or plants grown
in agricultural tunnels using
nanotechnology that fine-
tunes sunlight to boost
yields? Or cultured meat
grown in bioreactors? These
ideas have the potential to
transform industries but
they need a helping hand to
come to fruition. This is
exactly the aim of the
Innovation Centers of Merck
KGaA, Darmstadt, Germany.
The Innovation Center is a
“playground” for scientists
and entrepreneurs to
explore new fields and
develop new businesses
beyond the company’s
current scope. These teams
are now operating at the
company’s headquarters in
Darmstadt, Germany, with
additional hubs in Silicon
Making clean Currently, culture media costs hundreds Valley and China, with
of dollars per litre, but for clean meat involvement from colleagues
meat in the lab production to scale this needs to drop to around the world. “Our
around $1 a litre. innovation projects operate
Cells are Other challenges for the industry are to like startups,” says Lavanya
removed from develop the tissue scaffolds needed to Anandan, who is
the animal in support growth of the cells, and to engineer coordinating the clean
a biopsy the specialised bioreactors needed to meat innovation field at
scale-up production. the California site. “The
So when will the fruits of this cellular Innovation Center and
The cells agriculture reach the supermarket shelves? Innovation Hubs are building
are cultured In the next few years we can expect a few an ecosystem where we can
in the lab launches of small-scale products in high end grow viable new businesses
restaurants. “It will be a pretty expensive with the backing and know-
burger in a restaurant in Hong Kong or San how of a big company.”
The culture Francisco” says Anandan. “My prediction is In addition to the clean
is grown into that by 2030 you might see them on meat research, the
edible tissue in supermarket shelves at a decent price.” Innovation Center is working
a bioreactor on a laser-adjustable lens
Find out more at: https://bit.ly/2UTycQp replacements for people
Or scan the QR code below with cataracts, new
The tissue is technologies for structure
processed into analysis on a sub-microgram
food products scale and many other
such as burger challenges.
patties
Find out more at:
innovationcenter.emdgroup.com
Views Aperture
Photographers Brenda S.
& R. Duncan Kirkby
Location St Eustatius National
Marine Park, Dutch Caribbean
Gege Li
pe
In rfec
balance t
You have not one, but five separate appetites for key
components of food. Listen to them and you’ll only eat
what you need, say David Raubenheimer and
Stephen Simpson
S
TELLA lived on the outskirts of Cape dieticians have to use computer programs
Town, South Africa. It was a beautiful, to do it. But Stella didn’t have access to a
rural setting just below Table Mountain, program because she was a wild Cape baboon.
surrounded by vineyards, trees, wild fynbos The Stella study is one of many that we
heathland and scattered settlements. have been involved with over the course
In 2010, Caley Johnson, a graduate of our 30-year scientific collaboration.
student of anthropology at City University As a result, we think we have discovered
of New York, arrived to study Stella. For something profoundly important about
30 consecutive days she followed her, human nutrition, which changes how we
watching and recording exactly what, understand appetite, explains the obesity
and how much, she ate. epidemic – and suggests a way of solving it.
Stella’s diet was extremely diverse: Our journey began in 1991, when
almost 90 different foodstuffs over that we were colleagues at the University
time. On the surface, she didn’t appear of Oxford. We set out to answer two
particularly discerning. And indeed, the questions. First, how do animals choose
ratio of fats to carbohydrates in her diet what to eat? And second, what happens if
varied widely from day to day. they fail to follow a healthy diet? To find out,
But when Johnson crunched the numbers, we designed a huge experiment using the
something interesting popped out. When she most voracious and indiscriminate eaters
looked at the ratio of combined daily calories we could think of: locusts.
from carbs and fats to calories from protein, We put 200 young locusts in individual
she always got close to 4:1. This happened plastic boxes and prepared 25 different
every day, regardless of what Stella ate. Even foods containing various proportions
more interestingly, this ratio was very similar of protein and carbohydrates, the main
to what is considered nutritionally ideal nutrients the insects eat. The foods ranged
for a female of Stella’s size. Far from being from high-protein/low-carb to high-carb/
indiscriminate, Stella was a meticulously low-protein, and everything in between.
healthy eater. Each locust was fed just one of the
TOM STRAW
How did she calibrate her diet so precisely? 25 formulations, in unlimited quantities,
Doing so is difficult, and even professional until they reached adulthood and shed >
That was the purpose of the Stella study In phase 2, everyone maintained their evolution for good reasons. One is that
and many others that we have done. These absolute protein intake. But to do so, those there is a limit to how complex biological
have shown that appetite-driven nutrient on the low-protein diet had to eat 35 per cent systems can get and still operate efficiently.
balancing is common across the animal more total calories, while those assigned We couldn’t have specific appetites for dozens
kingdom. It has been documented in the high-protein diet ate 38 per cent fewer of nutrients. Another is that these nutrients
life forms as diverse as slime moulds, calories. Our volunteers responded like are needed in very specific quantities. Third,
cockroaches, beetles, spiders, cats, dogs, locusts, with their appetite for protein some components, like sodium, were often
mink and non-human primates. Some dominating, and determining the total rare in our ancestral environments and we
turn out to have not two, but five appetites, consumption of food. needed dedicated machinery to seek them
three for the main macronutrients (protein, out, for example in mineral deposits.
carbohydrates and fat) and two for specific What about vitamins and the other
micronutrients – sodium and calcium. Your five appetites essential minerals? We probably didn’t
Given a range of foods to eat, they will We later did two bigger and more evolve specific appetites for them because
always precisely calibrate their intake. sophisticated versions of the chalet our natural diets are rich in these nutrients,
This naturally got us thinking: do humans experiment, in Sydney and Jamaica, and and by eating the right amounts of the big
also have several appetites? found essentially the same thing: people on five, we automatically get enough of the rest.
Answering this question wasn’t going a low-protein diet consume more calories. As a result of our discoveries on the ways in
to be easy. Human nutrition science has The explanation for this is that humans which nutrient appetites interact – the dance
always been bedevilled by the difficulty of also have more than one appetite. In fact, of the appetites, as it were – we were confident
getting an accurate record of what people we have the five that our earlier research in putting forward another hypothesis: in a
eat. Most research relies on study subjects found in some other organisms: protein, food environment that is protein-poor but
self-reporting. The trouble is, people forget. carbs, fats, sodium and calcium. It is a mistake energy-rich, people will overeat carbs and fats
Ideally, you want to treat your human to think of appetite as a single, powerful drive as they strive to reach their protein target.
subjects like locusts: keep them in isolation to eat. We need separate appetites to keep If true, the implications would be huge.
with only the food you provide, all weighed track of various nutrients, and hence to It may come as a surprise, but we do actually
and measured. However, this doesn’t get construct a balanced diet. live in a protein-dilute, energy-rich food
people banging down the doors to volunteer Those five have been singled out by environment. According to the UN’s Food
as participants. and Agriculture Organization, between 1961
Fortunately, we found a compromise. and 2000, the proportion of protein in the
One of our students had access to an average US diet fell from 14 per cent to 12.5 per
isolated chalet in the Swiss Alps, far from cent, with the balance made up of fats and
shops or restaurants. She recruited a group carbs. Given that shift, the only way people
of 10 friends and family and took them in the US could have maintained their target
there to spend a week as human locusts. protein consumption was to increase total
For the first two days, participants chose calorie intake by 13 per cent – more than
whatever they wanted to eat from a highly enough to create an obesity epidemic.
varied buffet. Everything they ate was Intriguingly, in our experiments with
weighed, and their intake of calories, people, we found that most of the extra
protein, carbs and fat was recorded (caffeine, calories eaten by those on a low-protein
alcohol and chocolate weren’t available). diet came from savoury snacks, especially
On days three and four, the volunteers those that tasted of umami, the signature
MAXIMILIAN STOCK LTD/SCIENCE PHOTO LIBRARY
were divided into two groups. One group got flavour of protein. Protein-deprived subjects
a high-protein buffet, the other a low-protein, were craving things that tasted like protein,
high-carb and high-fat buffet. For the final even though they were made of carbs.
two days, they returned to the original diet. Our food environment is awash with such
In phase 1 of the experiment, our human umami-flavoured carbs and fats, which we
locusts reliably got about 18 per cent of call “protein decoys”: crisps, instant noodles,
their calories from protein, in keeping crackers and so on.
with studies that show people typically These are also known as ultra-processed
need 15 to 20 per cent. foods, which we now see as the main cause >
Journey to
the end of
the universe
Astrophysicist Katie Mack
studies the birth, life and death
of the cosmos. She shares her
predictions for the fate of
everything with Leah Crane
She spoke to New Scientist about her own on regular matter – we can’t see it. We think
story and that of the universe. that dark energy makes up even more of the
universe, about 68 per cent of everything.
Leah Crane: How did you get into cosmology? We know even less about dark energy, only
Katie Mack: As a kid I was always taking that it makes space expand so that galaxies
things apart and trying to understand how move apart at an ever-accelerating rate.
they worked. At some point, I was exposed It’s a confusing situation where we can
to Stephen Hawking’s writing, and that describe the universe perfectly, except
personality trait extended to the universe. for the fact we don’t understand its two
I was always drawn to the weird stuff like biggest components. >
whole universe ours, but for us, the end of the observable
universe is the end.
doesn’t care about any of it.
All we can do is make the best out of what
we have. There’s some amount of comfort
will die some day I have friends who don’t want me to talk to in the fact that we’re all in this together,
them about space because it’s big and scary, at the mercy of some of these bigger forces,
is hard to wrap but I personally find it somewhat comforting.
How do you feel about the end of the universe?
and that’s OK. ❚
Episode six is out now featuring Philip Pullman, who became a global sensation
with the His Dark Materials trilogy. The story of two children crossing into parallel
worlds in a quest to understand the nature of reality and humanity, the novels draw
on fantasy as well as theology, physics, evolutionary biology, and neuroscience.
New Scientist’s Rowan Hooper met with Pullman at his home in Oxford.
An evolving crisis
Insights into how viruses change over time can help us
cope with this pandemic and avoid future ones,
says Jonathan R. Goodman
S
EVERAL weeks before the novel countries and governments around the
coronavirus became a serious issue world are looking for “exit strategies”
in the UK, I attended a friend’s birthday from lockdown, talk of exposing people
party. Already, much of the conversation to the virus to build up herd immunity has
centred on the virus and the illness it causes, returned. It remains a dangerous idea.
covid-19. While most people were talking To understand why, it is crucial to think
about how to avoid catching it, one guest about how the virus is changing as it jumps
suggested that everybody “get infected to from host to host and circulates in the
boost their immune system”. human population. As biologist Theodosius
As a student of evolutionary biology, Dobzhansky said almost half a century ago:
the idea alarmed me. I became even more “Nothing in biology makes sense, except
concerned when, in early March, the UK’s in the light of evolution.” It may not seem
chief scientific adviser recommended that obvious, but evolutionary processes have
SEBASTIAN KAULITZKI/ALAMY
When humans
and animals are
crowded together,
virulent new
viruses can evolve
to adapt and survive. This rapid pace of and people crowd together. “High selective
evolution helps explain why viruses are the “Coronaviruses pressure allows one viral strain to become
most abundant type of organism we know of. more successful in a particular species,”
It also explains how a virus specialising in encode their says Stanley Perlman at the University of
infecting one host species can quickly adapt Iowa in Iowa City. “The more times it infects
to a new host – as long as the context is right genes in RNA a single host, the better it will do.”
for significant evolutionary change. In other words, Wuhan’s bustling market
rather than provided the conditions in which a virulent
strain of coronavirus could successfully
Deadly conditions DNA, so evolve adapt to a variety of host species, including
The importance of context for viral evolution humans. As with the swine flu outbreak, the
can be seen clearly with the H1N1 swine flu more quickly” current pandemic arose in conditions that
pandemic of 2009. The disease, which humanity created. This is the first lesson
probably killed more than 250,000 people evolution can teach us: pandemics tend to
globally, started when the influenza virus emerge when we put people and animals in
evolved within a densely packed pig farm close proximity – be they factory farms or live
in Mexico. The virus was able to become animal markets. We can’t stop viruses
extremely deadly, very quickly, because each evolving, but we can reduce the risk of future
new host was right next to the last one. In pandemics by changing these conditions.
such conditions, survival of the fittest An evolutionary perspective on swine flu
allowed the most aggressive, virulent strains also offers insights into what might happen
to run rampant through the population, next with SARS-CoV-2. As H1N1 moved
outcompeting the less deadly ones. Pigs are geographically from the epicentre of the
biologically similar enough to humans to pandemic, the disease became less deadly.
pass on the newly evolved strain, so there was This is a general trend for viruses and is seen
then an explosion of cases among people. in four other coronaviruses that have made
SARS-CoV-2 seems to have emerged under the leap to humans in recent centuries and
similar conditions. It probably originated in now cause a quarter of all common colds.
bats, which are reservoirs for many viruses To work out whether covid-19 will follow a
because their unusual metabolism makes similar evolutionary trajectory, we need to
them capable of hosting them without understand why the virulence of a virus
becoming ill. However, genetic comparisons changes as it spreads. The key here is that
indicate that by the time the covid-19 there is generally a trade-off between how
pandemic began there were intermediate lethal a virus is and how successfully it can
forms of the virus circulating in the Huanan spread. A pathogen that kills each host before
wet market in Wuhan, where live animals it has had time to infect other susceptible >
Widespread
testing is needed
to work out
whether covid-19
is becoming less
deadly with time
individuals will rapidly die out. So, while a Switzerland, who is a co-developer of
highly virulent strain can thrive in conditions “Just one Nextstrain. By comparing the random
where hosts are crowded together, once the mutations in different samples, the team
virus jumps into the wider population, mutation, if it’s can start to see how strains are related. This
natural selection will tend to favour strains lets them make what is called a phylogeny,
that are less deadly. Put bluntly, dead hosts the right one, an evolutionary history of the pathogen,
don’t travel, and so don’t spread the virus “which helps us track how the virus is
to new susceptible hosts. can radically spreading through time and space,” she says.
By this logic, SARS-CoV-2 should be losing Working out whether strains of SARS-
virulence. One way to find out is to track alter a virus’s CoV-2 are becoming less deadly is another
mortality rates and see whether, over time, matter, however. After decades of research on
fewer people with covid-19 are dying. That effect on us” the flu virus, geneticists still struggle to make
requires accurate universal testing to find predictions about which strains are more or
out how many people have been infected and less virulent. Coronaviruses are larger than
hence what proportion of them has died. typical RNA viruses – they have about 30,000
We don’t yet have that information, except bases of genetic information compared with
for a couple of small data sets, which is why just 13,000 in flu – and it is unclear exactly
our current estimates of death rates from what different genetic mutations represent
covid-19 vary so widely (see “How lethal is in terms of evolutionary adaptations. What is
covid-19?”, page 42). clear is that SARS-CoV-2 isn’t changing much
There is another approach, although it is genetically. “The amount of diversity we’re
even more challenging: real-time tracking seeing is basically nothing. The maximum
of pathogen evolution. In 2018, a group of difference is 40 differences in 29,000 bases,”
researchers set up an open-source project says Hodcroft. “There just hasn’t been time
called Nextstrain to do just that, looking at for [natural] selection to act.” That said,
a range of diseases from seasonal flu and we don’t know how much genetic change
measles to West Nile virus and Zika. Now they will be necessary to reduce the virulence
have turned their attention to SARS-CoV-2, of SARS-CoV-2. Just one mutation, if it is
analysing all publicly available genomic the right one, can fundamentally alter how
sequences of the virus, and using analytic a virus affects human populations, says
and visual tools to discover how it is Susanna Manrubia at the Spanish National
changing as it spreads across the planet. Centre for Biotechnology.
“We look at the genetic material of the On the other hand, there is a possibility
virus, evaluating the small changes over time that this particular virus won’t become
as the virus copies itself over and over,” says milder. “Evolutionary predictions are much
Emma Hodcroft at the University of Basel, like weather forecasting,” says Manrubia.
Quarantining
people with
virulent strains
of a virus can help
promote less
deadly ones
“There are just too many variables.” And viruses associated with high mortality
when it comes to predicting the evolutionary “If we can catch to determine any evolutionary changes,”
trajectory of SARS-CoV-2, two confounding says Ewald. In theory, we could artificially
factors stand out. First, there is the fact that SARS-CoV-2 select more benign strains by strictly
people tend to transmit the virus to others quarantining people infected with the most
very soon after they are infected, with some evolving, we virulent strains – and anyone who has been
evidence suggesting that between a quarter in contact with them. In practice, this might
and half of infections are asymptomatic. might even be not work, however. “Quarantining people
Then there is the huge variability in people’s with severe disease may lower the infection
responses, with a strain that causes minor or able to give it a rate, but not necessarily the overall severity
even asymptomatic disease in one individual of the illness,” says Perlman. Until we
able to kill another. “SARS-CoV-2 is spreading helping hand” understand why the same strain can be
successfully, so short-term evolutionary benign in one person and deadly in another,
changes aren’t necessary,” says Hodcroft. exposing people even to milder strains of
the virus is risky, which is why the idea of
herd immunity is problematic.
Losing virulence Of course, there is another way to gain herd
Others are more optimistic that SARS-CoV-2 immunity: vaccination. But until we have a
will become milder, although it is unknown vaccine, most experts say the best policy is
how long this might take. After all, crowded to limit the virus’s spread. Evolutionary
conditions in Wuhan led to the evolution thinking can help us cope, especially if we
of a virus that was both highly transmissible can integrate it into our predictive models
and highly virulent, and conditions are to forecast how SARS-CoV-2 is likely to
changing again as it circulates further from change through time and space. It will take
its source. That makes adaptation likely, unprecedented collaboration, but projects
even if the virus can be transmitted by like Nextstrain illustrate that this is already
people who lack symptoms, according to happening. Dobzhansky was right. Evolution
evolutionary biologist Paul Ewald at the can help us make sense of covid-19. It can
University of Louisville, Kentucky. also reduce the risk of another pandemic
If SARS-CoV-2 is becoming less deadly, then like this happening in the future. ❚
we will have less to fear from it as time passes.
What’s more, if we can catch it evolving we
might even be able to give it a helping hand. Jonathan R. Goodman is at the
“If mortality is declining, then the molecular Leverhulme Centre for Human
make-up of the viruses associated with low Evolutionary Studies, University
mortality can be compared with that of of Cambridge, UK
A
N ENGLISH clergyman called John Project to build a nuclear bomb. They showed
Michell first speculated in the 18th that when a massive star ran out of fuel at the
century what would happen if you end of its life, its core would collapse. Their
had a star so massive that its escape velocity calculations, performed without computers,
exceeded light speed. Back then, however, with just pure physics and equations, showed
most people thought of light as waves, and that this collapsed core would meet the
nobody really understood how waves could definition of a black hole. The hunt was on to
be trapped by gravity. So the whole idea of find examples in nature.
dark stars disappeared for about a century – What were we looking for? According to the
until we entered the world of Albert Einstein. theory, black holes essentially have only two
Einstein was a rock star of physics back in features. There’s the event horizon, which is
the day. His general theory of relativity is a not a physical surface, but an information
geometric theory of gravity. It says that mass membrane, a boundary between the outside
curves space, or to be more accurate mass- universe and the things and information
energy (because Einstein had demonstrated trapped in the black hole. Then there is a
these were equivalent with his equation E = point of infinite mass density called the
mc2), curves a unified space-time, creating singularity at the object’s centre.
what we call gravity. Now that’s a problem. Stephen Hawking
A black hole is just an object so massive once said black holes contain the seeds of
and dense that it curves space-time to the their own demise, because a singularity is
limit. That has truly odd effects. For example, a nonsensical thing; you cannot have
in general relativity, gravity slows time, a fact infinite mass density. That’s one of the things
that’s been confirmed in experiments on we still don’t know about black holes: do
Earth. At the boundary of a black hole, called singularities exist, and what does it mean if
the event horizon, gravity is so strong that they do?
EVENT HORIZON TELESCOPE COLLABORATION
“Stephen Hawking
showed that black
holes slowly lose
mass: they radiate
and eventually fizzle
away to nothing”
Thinking sideways
Being smart is not always about
the kind of intelligence measured
by IQ tests – sometimes your brain
has to be able to shift gear and
look at things from a completely
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of lateral thinking with this quiz
extracted from the New Scientist
book The Brain: A User’s Guide
sentence? Show this bold Prussian Packed with fascinating science on everything from
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I am not very happy acting pleased complex object in the known universe
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ACROSS DOWN
1 Large Pacific seabird, Sula nebouxii (4-6,5) 2 2013 book by Sheryl Sandberg (4,2)
9 Dune grass (6) 3 ___ seal, pinniped also called an otary (5) Cryptic
10 Form of reasoning based on how the subject 4 Relating to electrical resistance (5) Crossword #31
looks, walks and quacks (4,4) 5 After yesterday, before tomorrow (5) Answers
11 Data corruption (3,5) 6 10-sided polygon (7)
14 Margaret ___ , US astrophysicist (6) 7 Base-8 (5) ACROSS 7 Damage, 8 Adonis, 9 Germ,
10 Malinger, 11 Opacity, 13 Banal,
17 A Cen (5,8) 8 Yb (9)
15 Copse, 17 Sprucer, 20 Demijohn,
20 Medication and dye, discovered 1876 (9,4) 12 Vacant (5)
21 Code, 23 Insect, 24 Edited
23 ENSO warm phase (2,4) 13 Winged termite, for example (5)
25 State of equilibrium between Earth’s crust 15 Wingless parasite (5) DOWN 1 Cave, 2 Tarmac, 3 Fermata,
and mantle (8) 16 1954 sci-fi novel by Richard Matheson (1,2,6) 4 Pauli, 5 Cornea, 6 Sine wave,
28 Narrow-side foremost (8) 17 Filament-forming protein (5) 12 Proteins, 14 Spaniel, 16 Spider,
29 Meteor associated with the comet 18 1 to 1 (5) 18 Urchin, 19 Booth 22 Deed
Tempel–Tuttle (6) 19 Ankle bone (5)
30 Kort nozzle (in marine engineering) (6,9) 21 Big cat, Panthera pardus (7)
22 Neck brace (1,5)
24 Unreactive (5)
25 Interferometric synthetic aperture radar (5)
26 Wild flower, Primula elatior (5)
27 Online abuser or provocateur (5)
Our crosswords are
now solvable online
newscientist.com/crosswords
For that reason, we weren’t contacting us,” the firm replied. valuable coronavirus-countering
particularly surprised to see “The price is usd$24.05.” A bargain. fluid. Fortunately, according to the Written by Gilead Amit
WESTEND61/GETTY IMAGES
Rain and water running along A slower yet perhaps more
the street will percolate through straightforward approach
cracks in concrete that are would be to bury your body
caused by ground movement. beneath the sea or a lake bed, in
Water will also pass through an area where there is little oxygen
joints where the paving meets permeating into the substrate, so
other construction and soak This week’s new questions that scavengers cannot invade the
through many coarse or sediment and eat you.
bituminous surfacing materials. Rest stop Why didn’t we evolve to let parents get more sleep? Many soda lakes in Africa fit
Depending on the nature of the Wouldn’t offspring with well-rested parents be more likely this profile, although their alkali
subsoil, water will diffuse laterally to survive? Isabelle Chaize, London, UK water can be caustic, and might
to reach tree roots, particularly tap eat away at your remains. But
roots of some species that are set Worm welcome Worms stir up soil. Why don’t they harm the calcified remains of animals
deep. Some geological formations plant roots? Mike Griffiths, Croydon, Surrey, UK found around Lake Natron in
will also allow lateral diffusion Tanzania suggest that this
over considerable distances, method could work.
even many kilometres. Extreme preservation A good location might be in the Choose a lake with slow-moving
Driving rain falls on leaves Gulf of Mexico, in the area where currents, because the sediment
and twigs and often stays on If I wanted to be buried so that the Mississippi disgorges itself. being deposited will be fine-
these convex surfaces because I was eventually fossilised, for Parts of the Black Sea would also grained. This will lead to less
of the tendency of a jet of fluid possible discovery in the far future, be good candidates. disturbance and to better
to stay attached to a convex where would be the best location preservation of your soft parts
surface – known as the Coandǎ on Earth to do this? Jon Noad as a black carbon film, and with
effect. It then runs down the Calgary, Alberta, Canada luck may even preserve your
bark of branches, limbs and trunks Jonathan Wallace There are many ways to get facial features. Deep sea beds
and can percolate through the Newcastle upon Tyne, UK fossilised. If you want the process should also work well, which is
small area of loose material If your aim is to be fossilised to go quickly, then find a tree that what created the famous Burgess
directly over the root mass. after you die, I would suggest that exudes resin. Leave your body Shale in British Columbia,
Many species of tree can also you ask your relatives to sink at the base of the tree and allow Canada, for example.
absorb rainwater through their your body rapidly into one the resin to gradually cover it. The best option may be
leaves in order to survive. of the “dead zones” that occur Eventually, the resin will turn northern Australian coast.
If you observe the soils arising in some of the world’s seas. to amber. The only problem is The unique geochemistry of
from public utility excavations Where large rivers meet the that you would need to find a very the mangrove muds lead to
of paving, you may be surprised sea, the massive organic load large tree, because the amount of animals such as mangrove
by how moist they are. sometimes results in low-oxygen amber created by this process is lobsters (Thalassina anomala)
conditions over vast areas generally quite small. It might be becoming fossilised in as little
Tony Goddard that are largely devoid of most possible to fossilise your head, but as 5000 years.
Trelech, Carmarthenshire, UK living organisms. probably not your whole body. Burying your corpse here
In the late 1980s, I worked for In such anoxic conditions, Other places where at least should guarantee fossilisation,
what was, at the time, utility your body is unlikely to get eaten parts of your body could be with the bonus that a nodule
company Eastbourne Water. by fish, crustaceans or other encased in sediment include called a concretion will form
Back then, one of the water scavengers. At the same time, streams that run through around you that will preserve your
sample collectors told me that a the huge amount of sediment limestone. The dissolved skeleton in three dimensions. ❚
lot of trees got by because of the coming from the river as the
number of leaks from the mains current slows should ensure that
pipes. He even said that repairing your body will be rapidly covered Want to send us a question or answer?
the pipes led to trees dying. I hope by layers of sediment that will Email us at lastword@newscientist.com
this isn’t so much the case now, potentially become sedimentary Questions should be about everyday science phenomena
given the need to conserve water. rock in aeons to come. Full terms and conditions at newscientist.com/lw-terms
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