A punctured wound can lead to a local abscess containing Clostridium tetani spores. The spores develop into vegetative organisms locally and release tetanospasmin into the bloodstream, causing toxemia. The toxin enters motor neurons in the peripheral nervous system and blocks inhibitory neurotransmitters, resulting in spasmodic muscle contractions that cause symptoms like trismus, dysphagia, and gait problems.
A punctured wound can lead to a local abscess containing Clostridium tetani spores. The spores develop into vegetative organisms locally and release tetanospasmin into the bloodstream, causing toxemia. The toxin enters motor neurons in the peripheral nervous system and blocks inhibitory neurotransmitters, resulting in spasmodic muscle contractions that cause symptoms like trismus, dysphagia, and gait problems.
A punctured wound can lead to a local abscess containing Clostridium tetani spores. The spores develop into vegetative organisms locally and release tetanospasmin into the bloodstream, causing toxemia. The toxin enters motor neurons in the peripheral nervous system and blocks inhibitory neurotransmitters, resulting in spasmodic muscle contractions that cause symptoms like trismus, dysphagia, and gait problems.