Data Sheet

Polysep™ II Filters
Superior filters provide multiple filtration stages in a single
compact configuration for critical prefiltration applications.

Polysep™ II filters are ideal for a broad range of aqueous-

based applications. The Polysep™ II media consists of
a borosilicate glass layer and a layer of mixed esters of
cellulose membrane. The depth of the microfiber filter layer
provides high particle loading capacity, and retention of large
particulates while maintaining high flow rates. The mixed
cellulose ester membrane layers provide the high retention
needed during critical prefiltration steps while protecting
more expensive downstream filtration devices and equipment.

Cell Culture Media

Polysep™ II prefilters effectively remove particles including
lipids and colloidal contaminants without obstructing the
flow of vital media constituents.
Ophthalmics
Polysep™ II prefilters reduce particle and bioburden before
sterilizing filtration and will withstand process variability.
Benefits
• Combines the dirt-holding capacity of a depth filter with the
retention efficiency of a membrane filter
• Provides outstanding protection of more expensive downstream filters
• Exceptional retention efficiency for critical prefiltration processes

Serum • Perfect choice when high flow rate and high throughput are required
Polysep™ II prefilters remove lipids, colloids and particles from • Ideal for designing scalable solutions from bench top to full-scale
serum before final sterilizing filtration without obstructing the manufacturing
passage of serum proteins.

Large Volume Parenterals (LVP) Membrane Types Filter Formats

Extend the service life of downstream sterilizing filters by Polysep™ II • 
OptiScale® small-scale,
removing colloidal and particulate contaminants. The robust • 1.0/0.2/0.1 µm single-use capsule filters
design withstands high differential and operating pressures, • 1.0/0.2 µm • Opticap® XL and XLT
high flow rates and multiple steam-in-place or hot water • 1.0/0.5 µm single-use capsule filters
sanitization cycles.
• 1.0/1.2 µm • Cartridge filters
Buffer Preparation • 2.0/1.2 µm
Reduce particulate contamination and bioburden before Pore sizes are nominal
final sterilizing filtration and provide excellent protection for
sterilizing grade membrane filters in applications requiring
more extensive buffer prefiltration.
 Regulatory compliance
Filters with Polysep™ II membrane are designed,
developed and manufactured in accordance with a Quality
Management System approved by an accredited registering
body to an ISO® 9001 Quality Systems Standard and are
shipped with a Certificate of Quality. Each cartridge filter
is integrity tested during manufacturing and is supported
by a Validation Guide for compliance with regulatory
requirements. For traceability and easy identifi­cation, each
device is labeled with the product name and identifying
characteristics.

OptiScale® Process Development

Screening Tool
OptiScale® single-use capsule filters with Polysep™ II media provide a c­ onvenient small-
volume option for process screening and scaling. These “drop in” filters are ideal for
evaluating biopharmaceuticals. OptiScale® ­capsule filters offer speed-to-market strategies
for efficiently developing compounds and biotherapeutics.

The OptiScale® single-use capsule is ideally suited for process development and screening.
OptiScale® ­capsules are faster and easier to set up than conventional 47 mm discs.
OptiScale® Filters
Opticap® XL and XLT Single-Use Capsule Filters
Opticap® XL 2, 4, 5 and 10 Capsule Filters
Opticap® XL single-use capsule filters with Polysep™ II media are available in multiple
filtration areas, providing an optimal choice for every application. The unique capsule design
with pleated Polysep™ II media minimizes hold-up volume and reduces production losses.

Opticap® XLT 10, 20 and 30 Capsule Filters

Opticap® XLT single-use T-line capsule filters with Polysep™ II media are available with or
without a pressure gauge port for ease in monitoring process conditions. The T-line design
accommodates series or parallel filtration to match your application needs, and a specially-
designed stand enables quick and easy integration into your existing process.

Convenient and Easy to Use

Opticap® XL capsule filters eliminate the time and expense associated with assembly,
cleaning and validation of stainless steel housings. Adjustable, easy-to-turn upstream vents Opticap® XL Filters
and drain valves with o-ring seals and hose barb connections allow for easy process control.
Other ease-of-use features include flow directional arrows and ribbed edges for easy
gripping even with gloved hands.

The Right Size

A wide range of capsule sizes are available to fit all of your application needs, and allow
easy scale-up of your small volume filtration steps to larger, full-scale filtration processes.

Robust Construction
Opticap® XL and XLT’s capsule design allows unparalleled thermal and hydraulic stress
resistance in a single-use filter, resulting in reliability, high confidence in the sterility process
and improved cleanliness.

The Right Connections

Designed to optimize your filtration process, Opticap® XL and XLT single-use capsule filters
Opticap® XLT Filters
are available with a choice of inlet and outlet connections, including sanitary flanges,
Opticap® XLT
fractional sanitary flanges and hose barbs.
Capsule Stand

Cartridge Filters
Polysep™ II cartridge filters provide high throughput and flow rates with minimal
differential pressure. Cartridges are robust, designed to withstand multiple steam-in-place
cycles. A full range of filtration areas is available to suit your application requirements.
A variety of connection options are offered for easy adaptation to existing housings.

Cartridge Filters
 Specifications
OptiScale® Single-Use Capsules
Nominal Dimensions
Maximum length:
Diameter:
Weight:
Filtration Area (see legend below)
W1, W3, W6, W2, W9:
Materials of Construction
Filter media:
Structural components:
Vent cap:
Internal seal rings:
Housing Vent
Maximum Inlet Pressure
Oxidizable Substances
Sterilization
Good Manufacturing Practices
Non-Fiber Releasing
Component Material Toxicity
Indirect Food Additive
Legend for Filter Media Layer(s)
Nominal pore size of media
4
OptiScale®
82 mm (3.24 in.) with flange inlet/hose barb outlet
74 mm (2.91 in.) with flange inlet/flange outlet
94 mm (3.70 in.) with hose barb inlet/hose barb outlet
69 mm (2.75 in.)
2.4 oz (69 g)
17.7 cm2
Borosilicate glass microfiber and mixed esters of cellulose
Polycarbonate
PVDF
Fluoroelastomers
Adjustable vent with male luer and female Luer-Lok™ connections on inlet side of device.
5.5 bar (80 psi) at 25 °C
Capsules meet the requirements of the USP Oxidizable Substance for Sterile Water for Filtration Test after a water flush of
100 mL.
May be autoclaved for 3 cycles of 60 minutes at 121 °C
These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.
Polysep™ II media meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Component materials were tested and meet the criteria of the USP <88> Reactivity Test for Class VI Plastics.
Polysep™ II Filters meet the requirements of the current USP <88> Safety Test.
All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177–182.
W1 = 1.0/0.2/0.1 µm W2 = 1.0/1.2 µm
W3 = 1.0/0.2 µm W9 = 2.0/1.2 µm
W6 = 1.0/0.5 µm
Specifications
OptiCap® Single-Use Capsules
Opticap® XL 2 Opticap® XL 4 Opticap® XL 5 Opticap® XL 10 Opticap® XLT 10 Opticap® XLT 20 Opticap® XLT 30
Nominal Dimensions
Maximum length: 14.2 cm (5.6 in.) 19.6 cm (7.7 in.) 21.6 cm (8.5 in.) 33.5 cm (13.2 in.) 37.6 cm (14.8 in.) 62.5 cm (24.6 in.) 87.1 cm (34.3 in.)
Body Diameter 8.4 cm (3.3 in.) 8.4 cm (3.3 in.) 10.7 cm (4.2 in.) 10.7 cm (4.2 in.) — — —
Fitting to Fitting
Sanitary flange to — — — — 15.2 cm (6.0 in.) 15.2 cm (6.0 in.) 15.2 cm (6.0 in.)
sanitary flange:
Sanitary flange to — — — — 17.5 cm (6.9 in.) 17.5 cm (6.9 in.) 17.5 cm (6.9 in.)
hose barb:
Hose barb to hose barb: — — — — 19.8 cm (7.8 in.) 19.8 cm (7.8 in.) 19.8 cm (7.8 in.)
Filtration Area
(see legend below)
W2, W3, W6, W9: 0.06 m2 (0.6 ft2) 0.11 m2 (1.2 ft2) 0.19 m2 (2.0 ft2) 0.46 m2 (5.0 ft2) 0.46 m2 (5.0 ft2) 0.93 m² (10.0 ft²) 1.39 m² (15.0 ft²)
W1: N/A N/A 0.17 m2 (1.8 ft2) 0.42 m2 (4.5 ft2) 0.42 m2 (4.5 ft2) 0.85 m² (9.1 ft²) 1.26 m2 (13.6 ft2)
Materials of Construction
Filter media: Borosilicate glass microfiber and mixed esters of cellulose
Structural components*: Polypropylene
Supports: Polypropylene
Vent cap: Polypropylene
Vent O-ring: Silicone
Vent/Drain ¼ in. hose barb with double O-ring seal
Maximum Inlet Pressure 5.5 bar (80 psi) at 23 °C
2.8 bar (40 psi) at 60 °C
1.0 bar (15 psi) at 80 °C
Maximum Differential
Pressure
Forward: 3.4 bar (50 psid) at 25 °C.
NVR Gravimetric After autoclaving and a 24 hour soak in ASTM® Type 1 reagent grade water at controlled room temperature:
Extractables
≤ 45 mg after ≤ 85 mg after ≤ 61 mg after ≤ 145 mg after ≤ 145 mg after ≤ 290 mg after ≤ 435 mg after
a 600 mL flush a 1.2 L flush a 5 L flush a 5 L flush a 5 L flush a 10 L flush a 15 L flush
USP Bacterial Endotoxin Aqueous extraction contains < 0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test.
Oxidizable Substances Capsules meet the requirements of the USP Oxidizable Substances Test after a water flush of:
≤ 1000 mL ≤ 2000 mL ≤ 2000 mL ≤ 5000 mL ≤ 5000 mL ≤ 10,000 mL ≤ 15,000 mL
Sterilization May be autoclaved for 3 cycles of 30 minutes at 121 °C. (Cannot be steam sterilized in-line.)
Good Manufacturing These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.
Practices
Non-Fiber Releasing Polysep™ II media meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Component Material Component materials meet the requirements of the USP <88> Reactivity Tests for Class VI Plastics.
Toxicity This product meets the requirements of the USP <88> Safety Test utilizing a 0.9% sodium chloride extraction.
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177–182.

*Cage, core, end caps and capsule housing

Legend for Filter Media Layer(s)

Nominal pore size of media W1 = 1.0/0.2/0.1 µm W2 = 1.0/1.2 µm

W3 = 1.0/0.2 µm W9 = 2.0/1.2 µm
W6 = 1.0/0.5 µm

5
 Specifications (continued)
4-inch Cartridge Per 10-inch Cartridge
Nominal Dimensions
Outside diameter: 6.9 cm (2.7 in.) 6.9 cm (2.7 in.)
Filtration Area (see legend below)
W2, W3, W6, W9: 0.19 m2 (2.0 ft2) 0.46 m2 (5.0 ft2)
W1: 0.17 m2 (1.8 ft2) 0.42 m2 (4.5 ft2)
Materials of Construction
Filter media: Borosilicate glass microfiber and mixed esters of cellulose
Structural components*: Rigid polypropylene
Supports: Spun bonded polypropylene
O-rings: Silicone
Maximum Differential Pressure
Forward: 3.4 bar (50 psid) at 25 °C.
NVR Gravimetric Extractables After autoclaving and a 24 hour soak in ASTM® Type 1reagent grade water at controlled room temperature,
extractables level was ≤ 140 mg per 10-inch element after a 5000 mL flush.
Bacterial Endotoxin Aqueous extraction contains < 0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test.
Oxidizable Substances Cartridges meet the requirements of the USP Oxidizable Substances Test after a water flush of ≤ 5000 mL per 10-inch
element.
Sterilization May be autoclaved for 10 cycles of 30 minutes at 121 °C, or steam sterilized for 10 cycles of 30 minutes at 121 °C, or
hot water sanitized for 40 cycles of 30 minutes at 80 °C.
Good Manufacturing Practices These products are manufactured in a facility which adheres to FDA Good Manfacturing Practices.
Non-Fiber Releasing Polysep™ II media meets the criteria for a “non-fiber releasing” filter as defined in 21 CFR 210.3 (b) (6).
Component Material Toxicity Component materials meet the requirements of the USP <88> Reactivity Tests for Class VI Plastics.
This product meets the requirements of the USP <88> Safety Test utilizing a 0.9% sodium chloride extraction.
Indirect Food Additive All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177–182.

*Cage, core, end caps and capsule housing

Legend for Filter Media Layer(s)

Nominal pore size of media W1 = 1.0/0.2/0.1 µm W2 = 1.0/1.2 µm

W3 = 1.0/0.2 µm W9 = 2.0/1.2 µm
W6 = 1.0/0.5 µm

6
 Typical Clean Water Flow Rates

Opticap® XL 2 Capsule with Polysep™ II Opticap® XL 2 Capsule with Polysep™ II Opticap® XL Capsule Legends Refers
Media — 1.0/0.2 µm Nominal (W3) Media — 1.0/0.5 µm Nominal (W6) to Connection Type
gpm gpm
0 1 2 3 4 5 0 1 2 3 4 5
TT = 3 8 mm (11⁄2 in.) Sanitary
2.5
35
1.6 Flange Inlet and Outlet
TT
30
1.4
TT
FF 20 FF = 1 9 mm (3⁄4 in.) Sanitary Flange
2.0 FF
HH 1.2 HH Inlet and Outlet
FH 25 FH
Pressure Drop (bar)

Pressure Drop (bar)

1.5 1.0 15 HH = 1 4 mm (9⁄16 in.) Hose Barb Inlet
20
0.8
and Outlet
1.0 15
0.6
10
FH = 1 9 mm (3⁄4 in.) Sanitary Flange
10 Inlet and 14 mm (9⁄16 in.) Hose
0.4
0.5 5 Barb Outlet
5 psid 0.2

psid
0.0 0 0.0 0
0 2 4 6 8 10 12 14 16 18 20 0 2 4 6 8 10 12 14 16 18 20

Flow Rate (L/min) Flow Rate (L/min)

Opticap® XL 2 Capsule with Polysep™ II Opticap® XL 2 Capsule with Polysep™ II

Media — 1.0/1.2 µm Nominal (W2) Media — 2.0/1.2 µm Nominal (W9)
gpm gpm
0 1 2 3 4 5 0 1 2 3 4 5
0.9 0.7 10
0.8 TT TT 9
0.6
FF FF 8
0.7
Differential Pressure (bar)

HH 10 HH
FH 0.5 FH 7
Pressure Drop (bar)

0.6
6
0.5 0.4
5
0.4 0.3
5 4
0.3
0.2 3
0.2
2
0.1 0.1
1
psid

psid
0.0 0 0.0 0
0 2 4 6 8 10 12 14 16 18 20 0 2 4 6 8 10 12 14 16 18 20

Flow Rate (L/min) Flow Rate (L/min)

Opticap® XL 4 Capsule with Polysep™ II Opticap® XL 4 Capsule with Polysep™ II

Media — 1.0/0.2 µm Nominal (W3) Media — 1.0/0.5 µm Nominal (W6)
gpm gpm
0 1 2 3 4 5 0 1 2 3 4 5
1.4 20 1.0 14

TT 0.9 TT
1.2 12
FF 0.8 FF
HH 15 HH
1.0 FH 0.7 FH 10
Pressure Drop (bar)
Pressure Drop (bar)

0.6
0.8 8
10 0.5
0.6 0.4 6

0.4 0.3 4
5
0.2
0.2 2
0.1
psid

psid

0.0 0 0.0 0
0 2 4 6 8 10 12 14 16 18 20 0 2 4 6 8 10 12 14 16 18 20

Flow Rate (L/min) Flow Rate (L/min)

Opticap® XL 4 Capsule with Polysep™ II Opticap® XL 4 Capsule with Polysep™ II

Media — 1.0/1.2 µm Nominal (W2) Media — 2.0/1.2 µm Nominal (W9)
gpm gpm
0 1 2 3 4 5 0 1 2 3 4 5
0.7 10 0.6
8
TT 9 TT
0.6 0.5
FF 8 FF 7
HH HH
0.5 FH 7 FH 6
Pressure Drop (bar)

Pressure Drop (bar)

0.4
6 5
0.4
5 0.3
4
0.3 4
0.2 3
0.2 3
2 2
0.1
0.1 1
1
psid

psid

0.0 0 0.0 0
0 2 4 6 8 10 12 14 16 18 20 0 2 4 6 8 10 12 14 16 18 20

Flow Rate (L/min) Flow Rate (L/min)

7
 Typical Clean Water Flow Rates

Opticap® XL 5 Capsule with Polysep™ II Opticap® XL 5 Capsule with Polysep™ II Opticap® XL Capsule Legends Refers
Media — 1.0/0.2/0.1 µm Nominal (W1) Media — 1.0/0.2 µm Nominal (W3) to Connection Type
gpm gpm TT = 3 8 mm (11⁄2 in.) Sanitary
0 2 4 6 8
3.5 3.0
0 5 10 15 20
Flange Inlet and Outlet
50

3.0 TT 45 TT
40 FF = 1 9 mm (3⁄4 in.) Sanitary Flange
2.5
FF 40
FF
HH
Inlet and Outlet
2.5 HH
30 HH = 1 4 mm (9⁄16 in.) Hose Barb Inlet
Pressure Drop (bar)

Pressure Drop (bar)

35 2.0
2.0 30 and Outlet
25 1.5
20
1.5
20
1.0
1.0 15
10
10 0.5
0.5
5
psid

psid
0.0 0 0.0 0
0 5 10 15 20 25 30 35 0 10 2 0 30 40 50 60 70 80

Flow Rate (L/min) Flow Rate (L/min)

Opticap® XL 5 Capsule with Polysep™ II Opticap® XL 5 Capsule with Polysep™ II Opticap® XL 5 Capsule with Polysep™ II
Media — 1.0/0.5 µm Nominal (W6) Media — 1.0/1.2 µm Nominal (W2) Media — 2.0/1.2 µm Nominal (W9)
gpm gpm gpm
0 5 10 15 20 0 5 10 15 20 0 1 2 3 4 5 6 7
2.5 2.5 2.5
35 35
TT TT TT
FF 30 30 FF 25
2.0 2.0 FF 2.0
HH HH HH
25 25
Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

20
1.5 1.5 1.5
20 20
15

1.0 15 1.0 15 1.0

10
10 10
0.5 0.5 0.5 5
5 5
psid

psid

psid
bar

0.0 0 0.0 0 0.0 0

0 10 2 0 30 40 50 60 70 80 0 10 20 30 4 0 50 60 70 80 0 5 10 20 30 40 50
L/min
Flow Rate (L/min) Flow Rate (L/min) Flow Rate (L/min)

Opticap® XL 10 Capsule with Polysep™ II Opticap® XL 10 Capsule with Polysep™ II Opticap® XL 10 Capsule with Polysep™ II
Media — 1.0/0.2/0.1 µm Nominal (W1) Media — 1.0/0.2 µm Nominal (W3) Media — 1.0/0.5 µm Nominal (W6)
gpm gpm gpm
0 5 10 15 20 0 5 10 15 20 0 5 10 15 20
2.5 2.5 2.5
35 35 35
TT TT TT
2.0 FF 30 2.0 FF 30 2.0 FF 30
HH HH HH
Pressure Drop (bar)

25
Pressure Drop (bar)
Pressure Drop (bar)

25 25
1.5 1.5 1.5
20 20 20

1.0 15 1.0 15 1.0 15

10 10 10
0.5 0.5 0.5
5 5 5
psid

psid

psid

0.0 0 0.0 0 0.0 0

0 10 20 30 4 0 50 60 70 80 0 10 2 0 30 40 50 60 70 80 0 10 2 0 30 40 50 60 70 80
Flow Rate (L/min) Flow Rate (L/min) Flow Rate (L/min)

Opticap® XL 10 Capsule with Polysep™ II Opticap® XL 10 Capsule with Polysep™ II

Media — 1.0/1.2 µm Nominal (W2) Media — 2.0/1.2 µm Nominal (W9)
gpm gpm
0 5 10 15 20 0 5 10 15 20
2.5 2.5
35 35
TT TT
2.0 FF 30 2.0 FF 30
HH HH
25 25
Pressure Drop (bar)

Pressure Drop (bar)

1.5 1.5
20 20

1.0 15 1.0 15

10 10
0.5 0.5
5 5
psid

psid

0.0 0 0.0 0
0 10 2 0 30 40 50 60 70 80 0 10 2 0 30 40 50 60 70 80

Flow Rate (L/min) Flow Rate (L/min)

8
Typical Clean Water Flow Rates

Opticap® XLT 10 Capsule with Polysep™ II Opticap® XLT 10 Capsule with Polysep™ II Opticap XLT Capsule Legends Refer
Media — 1.0/0.2/0.1 µm Nominal (W1) Media — 1.0/0.2 µm Nominal (W3) to Connection Type
gpm gpm TT = 3 8 mm (11⁄2 in.) Sanitary Flange
0 5 10 15 20 0 5 10 15 20 Inlet and Outlet
4.0 3.0
TT
55 40 TH = 3 8 mm (11⁄2 in.) Sanitary Flange
3.5 50 TT
TH
45
2.5 TH Inlet and 16 mm (5⁄8 in.) Hose Barb Outlet
3.0 HH HH
BB 40 30 HH = 1 6 mm (5⁄8 in.) Hose Barb Inlet and Outlet
Pressure Drop (bar)

Pressure Drop (bar)

2.0 BB
2.5 35
30
BB = 2 5 mm (1 in.) Hose Barb Inlet and Outlet
2.0 1.5
20
25
1.5
20 1.0
1.0 15 10
10 0.5
0.5
5
psid

psid
0.0 0 0.0 0

Flow Rate (L/min) Flow Rate (L/min)

Opticap® XLT 10 Capsule with Polysep™ II Opticap® XLT 10 Capsule with Polysep™ II Opticap® XLT 10 Capsule with Polysep™ II
Media — 1.0/0.5 µm Nominal (W6) Media — 1.0/1.2 µm Nominal (W2) Media — 2.0/1.2 µm Nominal (W9)
gpm gpm gpm
0 5 10 15 20 0 5 10 15 20 0 5 10 15 20
3.0 3.0 3.0
40 40 40
TT TT TT
2.5 2.5 TH 2.5
TH TH
HH HH HH
30 BB 30 30
Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

2.0 BB 2.0 2.0 BB

1.5 1.5 1.5

20 20 20

1.0 1.0 1.0

10 10 10
0.5 0.5 0.5
psid

psid

psid
0.0 0 0.0 0 0.0 0
0 10 20 30 4 0 50 60 70 80

Flow Rate (L/min) Flow Rate (L/min) Flow Rate (L/min)

Opticap® XLT 20 Capsule with Polysep™ II Opticap® XLT 20 Capsule with Polysep™ II Opticap® XLT 20 Capsule with Polysep™ II
Media — 1.0/0.2/0.1 µm Nominal (W1) Media — 1.0/0.2 µm Nominal (W3) Media — 1.0/0.5 µm Nominal (W6)
gpm gpm gpm
0 5 10 15 20 0 5 10 15 20 0 5 10 15 20
3.5 50 3.0 3.0
40 40
3.0 TT 45 TT TT
TH 2.5 TH 2.5 TH
40
HH HH HH
2.5 30 30
BB 35 BB BB
Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

2.0 2.0
2.0 30
25 1.5 1.5
20 20
1.5
20
1.0 1.0
1.0 15
10 10
10
0.5 0.5 0.5
5
psid

psid

psid

0.0 0 0.0 0 0.0 0

0 10 20 30 4 0 50 60 70 80
Flow Rate (L/min) Flow Rate (L/min) Flow Rate (L/min)

Opticap® XLT 20 Capsule with Polysep™ II Opticap® XLT 20 Capsule with Polysep™ II
Media — 1.0/1.2 µm Nominal (W2) Media — 2.0/1.2 µm Nominal (W9)
gpm gpm
0 5 10 15 20 0 5 10 15 20
3.0 3.0
40 40
TT TT
2.5 TH 2.5
TH
HH HH
BB 30 30
Pressure Drop (bar)

Pressure Drop (bar)

2.0 2.0 BB

1.5 1.5
20 20

1.0 1.0
10 10
0.5 0.5
psid

psid

0.0 0 0.0 0

Flow Rate (L/min) Flow Rate (L/min)

9
 Typical Clean Water Flow Rates

Opticap® XLT 30 Capsule with Polysep™ II Opticap XLT 30 Capsule with Polysep™ II Opticap® XLT Capsule Legends Refer
Media — 1.0/0.2/0.1 µm Nominal (W1) Media — 1.0/0.2 µm Nominal (W3) to Connection Type
gpm gpm TT = 38 mm (11⁄2 in.) Sanitary Flange Inlet
0 5 10 15 20 0 5 10 15 20 and Outlet
3.0 3.0

TT
40 40 TH = 38 mm (11⁄2 in.) Sanitary Flange Inlet
TT
2.5 TH 2.5 TH and 16 mm (5⁄8 in.) Hose Barb Outlet
HH HH
BB 30 BB 30 HH = 16 mm (5⁄8 in.) Hose Barb Inlet
Pressure Drop (bar)

Pressure Drop (bar)

2.0 2.0
and Outlet
1.5 1.5
20 20 BB = 25 mm (1 in.) Hose Barb Inlet
1.0 1.0 and Outlet
10 10
0.5 0.5
psid

psid
0.0 0 0.0 0

Flow Rate (L/min) Flow Rate (L/min)

Opticap XLT 30 Capsule with Polysep™ II Opticap XLT 30 Capsule with Polysep™ II Opticap XLT 30 Capsule with Polysep™ II
Media — 1.0/0.5 µm Nominal (W6) Media — 1.0/1.2 µm Nominal (W2) Media — 2.0/1.2 µm Nominal (W9)
gpm gpm gpm
0 5 10 15 20 0 5 10 15 20 0 5 10 15 20
3.0 3.0 3.0
40 40 40
TT TT TT
2.5 TH 2.5 2.5
TH TH
HH HH HH
BB 30 30 30
Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

2.0 2.0 BB 2.0 BB

1.5 1.5 1.5

20 20 20

1.0 1.0 1.0

10 10 10
0.5 0.5 0.5
psid

psid

psid
0.0 0 0.0 0 0.0 0

Flow Rate (L/min) Flow Rate (L/min) Flow Rate (L/min)

Cartridges with Polysep™ II Media — Cartridges with Polysep™ II Media — 1.0/0.2 Cartridges with Polysep™ II Media —
1.0/0.2/0.1 µm Nominal (W1) µm Nominal (W3) 1.0/0.5 µm Nominal (W6)
gpm gpm gpm
0 5 10 1 5 20 0 5 10 1 5 20 0 5 10 1 5 20
2.5 0.7 10 0.35 5
35
4-inch 4-inch 4-inch
10-inch 0.6 10-inch 0.30 10-inch
2.0 20-inch 30 20-inch 8 20-inch 4
30-inch 0.5 30-inch 0.25 30-inch
Pressure Drop (bar)

Pressure Drop (bar)

Pressure Drop (bar)

40-inch 25 40-inch 40-inch

1.5 6 3
0.4 0.20
20

15 0.3 0.15
1.0 4 2

10 0.2 0.10
0.5 2 1
5 0.1 0.05
psid

psid

psid

0.0 0 0.0 0 0.00 0

Flow Rate (L/min) Flow Rate (L/min) Flow Rate (L/min)

Cartridges with Polysep™ II Media — Cartridges with Polysep™ II Media —

1.0/1.2 µm Nominal (W2) 2.0/1.2 µm Nominal (W9)
gpm gpm
0 5 10 1 5 20 0 5 10 1 5 20
0.7 10 0.16
4-inch 4-inch
0.6 10-inch 0.14 10-inch 2.0
20-inch 8 20-inch
30-inch 0.12 30-inch
0.5
Pressure Drop (bar)

Pressure Drop (bar)

40-inch 40-inch
0.10 1.5
0.4 6
0.08
0.3 1.0
4 0.06
0.2
0.04
2 0.5
0.1 0.02
psid

psid

0.0 0 0.00 0.0

Flow Rate (L/min) Flow Rate (L/min)

10
Ordering Information
OptiScale® Capsule Filters

S G A 4 7 3

OptiScale® May be Autoclaved Quantity per Package

Capsule Filter 3 = 3/pk
Pore Size (nominal) Connection Type
Media Type
W1 = 1.0/0.2/0.1 µm HH = 6 mm (1⁄4 in.) Hose Barb Inlet and Outlet
G = Polysep™ II
W3 = 1.0/0.2 µm FF = 19 mm (3⁄4 in.) Sanitary Flange Inlet and Outlet
W6 = 1.0/0.5 µm FH = 19 mm (3⁄4 in.) Sanitary Flange Inlet and
W2 = 1.0/1.2 µm 6 mm (1⁄4 in.) Hose Barb Outlet
W9 = 2.0/1.2 µm

Opticap® XL Capsule Filters*

K G A

Opticap® XL May be Autoclaved Capsule Size Quantity per Package

Capsule Filter 02 = Opticap® XL 2 1 = 1/pk (XL 5 and XL 10)
04 = Opticap® XL 4 3 = 3/pk (XL 2 and XL 4)
05 = Opticap® XL 5
Pore Size (nominal) 10 = Opticap® XL 10
Media Type
G = Polysep™ II W1 = 1.0/0.2/0.1 µm
Connection Type
W3 = 1.0/0.2 µm
TT = 38 mm (11⁄2 in.) Sanitary Flange Inlet and Outlet
W6 = 1.0/0.5 µm
FF = 19 mm (3⁄4 in.) Sanitary Flange Inlet and Outlet
W2 = 1.0/1.2 µm
HH = 14 mm (9⁄16 in.) Hose Barb Inlet and Outlet
W9 = 2.0/1.2 µm
FH = 19 mm (3⁄4 in.) Sanitary Flange Inlet and
14 mm (9⁄16 in.) Hose Barb Outlet (XL 2 and XL 4 only)

Opticap® XLT Capsule Filters*

K G A 1

Opticap® XLT May be Autoclaved Gauge Port Quantity per Package

Capsule Filter T = Without 1 = 1/pk
Pore Size (nominal) Gauge Port
Media Type W1 = 1.0/0.2/0.1 µm Capsule Size
W3 = 1.0/0.2 µm Connection Type
G = Polysep™ II 1 = Opticap® XLT 10
W6 = 1.0/0.5 µm 2 = Opticap® XLT 20 TT = 38 mm (11⁄2 in.) Sanitary Flange Inlet and Outlet
W2 = 1.0/1.2 µm 3 = Opticap® XLT 30 HH = 16 mm (5⁄8 in.) Hose Barb Inlet and Outlet
W9 = 2.0/1.2 µm TH = 38 mm (11⁄2 in.) Sanitary Flange Inlet and
16 mm (5⁄8 in.) Hose Barb Outlet
BB = 25 mm (1 in.) Sanitary Flange Inlet

Accessory
Description Qty/Pk Catalogue No.
Standard Opticap® XLT Capsule Filter Stand 1/pk XLTS TAN D1
*Not all configurations available as standard product.
11
Ordering Information
Cartridge Filters

C G T 0 3

Cartridge Filter Quantity per

O-ring Material Package
Membrane Type S = Silicone (standard) 03 = 3/pk
G = Polysep™ II Cartridge Length E = EP gasket
1 = 10-inch (standard on flat seal only)
Pore Size (nominal) 2 = 20-inch V = Fluorocarbon (special order)
W1 = 1.0/0.2/0.1 µm 3 = 30-inch
Cartridge Code 4 = 40-inch
W3 = 1.0/0.2 µm
O = (2-222) O-ring 4 = 4-inch (cartridge codes M and N only)
W6 = 1.0/0.5 µm
5 = (2-222) O-ring w/spear
W2 = 1.0/1.2 µm
7 = (2-226) O-ring w/locking tab and spear
W9 = 2.0/1.2 µm
F = Double open end flat gasket
M = (2-118) O-ring (4-inch cartridge only)
N = (2-226) O-ring (4-inch cartridge only)

To Place an Order or Receive

Technical Assistance
In the U.S. and Canada, call toll-free
1(800)-645-5476
For other countries across Europe, call
+44 (0) 115 943 0840
For other countries across Europe and the world,
please visit www.merckmillipore.com/offices
For Technical Service, please visit
www.merckmillipore.com/techservice

www.merckmillipore.com/offices

Merck Millipore, the M logo, Opticap, and OptiScale are registered trademarks and
Polygard is a trademark of Merck KGaA, Darmstadt, Germany.
ISO is a registered trademark of the International Organization for Standardization.
ASTM is a trademark of American Society for Testing and Materials.
Luer-Lok is a trademark of Becton Dickinson and Company.
Lit. No. DS180EN00 Ver. 1.0 12/2015 PS-13-09383
© 2015 EMD Millipore Corporation, Billerica, MA U.S.A. 01821 All rights reserved.