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927020 Coronavirus may die heart musele fibers into thy snippets, remove cel’ DNA Coronavirus may dice heart muscle fibers into tiny snippets, remove cells‘ DNA The new coronavirus seems to slice heart muscle fibers into small, precisely sized fragments — at least when it infects heart cells in a lab dish, a new study reveals. thea heat muse cas wehbe long Rusa ae temo race On te rac an tage ees asc as neced win SBRS-CoV-2 ech lng fers oppeed he This sniping of muscle fibers, which could permanently damage heart cells, is scary enough in a lab dish; but the researchers found evidence that a similar process could be happening in the hearts of COVID-19 patients as well, However, the new finding, which was published to the preprint database bioRXiv on Aug. 25, has not yet been published in a peer-reviewed journal, or proven to happen in people. The finding is unlike anything researchers have seen before —no other disease is known to affect heart cells in this way. "What we were seeing was completely abnormal,” study co-author Todd McDevitt, a senior investigator at Gladstone Institutes, a nonprofit research organization in San Francisco, said in a statement. The new finding may explain how COVID-19 inflicts damage to the heart. Previous studies have found signs of heart abnormalities in COVID-19 patients, including inflammation of the heart muscle, even in relatively mild cases. Related: Top 10 amazing facts about your heart For the new study, the researchers used special stem cells to create three types of heart cells, known as cardiomyacytes, cardiac fibroblasts and endothelial cells. In lab dishes, these cells were then exposed to SARS-CoV-2, the virus that causes hitpshwww.men comlen-usihealtymedica/eoronavius-may-doe-he wedgntp 116 stsusco-tbers.into-iny-snppots-romove-clls-dhalar-BB18S4EA47o«h 927020 Coronavirus may die heart musele fibers into thy snippets, remove cel’ DNA COVID-19. OF the three types of cells, SARS-CoV-2 could infect and make copies of itself only inside cardiomyocytes, or heart Cardiomyocytes contain muscle fibers that are made up of units called sarcomeres, which are critical to the muscle contractions that produce a heartbeat, These sarcomeres usually line up in the same direction to form long filaments. 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