FORMULARY

Association of
Primate Veterinarians

APV Primate Formulary

Compiled By
D. Rick Lee, DVM and CJ Doane, DVM
Alamogordo Primate Facility
Thanks to the generous support of the
Griffin Foundation

DISCLAIMER: The drug doses listed in this formulary were taken from several
references and the authors' personal experience. As always, exercise professional
judgement when selecting a dose. While every effort has been made to ensure the
accuracy of information contained herein, the publisher, editor and contributors are not
legally responsible for errors or omissions.
TABLE OF CONTENTS

FORMULARY
Antibiotics
Analgesics / Anti-Inflammatories
Anesthesics / Sedatives
Antiparasitic
Antifungal
Cardiovascular
Vitamins / Supplements
Miscellaneous
Emergency

NORMAL VALUES
Chimpanzees

NEW WORLD NORMAL VALUES

Bolivian Squirrel Monkey
Owl Monkey

OLD WORLD NORMAL VALUES

Baboon
Rhesus
Cynomologus

References

National B Virus Resource Center

ANTIBIOTICS ANTIBIOTICS
Drug Monkey Drug
Amikacin 5mg/kg IM TID Amikacin
Amoxicillin 6.7-13.3mg/kg IM/PO TID Amoxicillin
Amoxicillin/Clavulonic Acid 6.7-13.3mg/kg PO TID Amoxicillin/Clavulonic Acid
Ampicillin 25-50mg/kg/day IV/IM div TID-QID; Ampicillin
meningitis/septicemia 150-200mg/kg/day div
q3-4hrs
Azithromycin 40mg/kg PO SID 1st day; then 20mg/kg PO Azithromycin
SID 2-5th days
Cefataxime 50mg/kg IM TID Cefataxime
Cefazolin 20mg/kg IV/IM TID Cefazolin
Ceftiofur 2.2mg/kg IM SID Ceftiofur
Ceftriaxone 50mg/kg IM SID Ceftriaxone
Cephalexin 30mg/kg PO BID Cephalexin
Chloramphenicol Palmitate 25mg/kg PO TID Infants Chloramphenicol Palmitate
Chloramphenicol Succinate 33.3mg/kg IM TID Adults Chloramphenicol Succinate
Ciprofloxacin 10mg/kg PO BID Ciprofloxacin
Clarithromycin Clarithromycin
Clindamycin 12.5mg/kg IM TID Clindamycin
Doxycycline 2.5mg/kg PO BID 1st day; 2.5mg/kg PO SID Doxycycline
day 2
Enrofloxacin 5mg/kg IM/PO SID/BID Enrofloxacin
Erythromycin 35mg/kg PO TID; 15-20mg/kg/day IM BID Erythromycin
Furazolidone 10mg/kg PO BID Furazolidone
Gentamicin 2-4mg/kg IM BID Gentamicin
Levoquin Levoquin
Metronidazole 50mg/kg PO SID Metronidazole
Minocycline 4mg/kg PO Minocycline
Neomycin 50mg/kg PO BID Neomycin
Ofloxacin Ofloxacin
Oxacillin 16.7mg/kg IM TID Oxacillin
Oxytetracycline 25-50mg/kg PO; 10mg/kg IM/SQ Oxytetracycline
Penicillin G Benzathine 20,000-60,000 IU/kg IM SID Penicillin G Benzathine
Penicillin G Potassium 6,700-13,300 IU/kg IV/IM TID Penicillin G Potassium
Penicillin G Procaine 20,000-40,000 IU/kg IM/SQ BID Penicillin G Procaine
Penicillin V Potassium Penicillin V Potassium
Rifampin Rifampin
Rifampin/Isoniazid Rifampin/Isoniazid
Streptomycin 2.5-5mg/kg IM BID Streptomycin
Sulfadimethoxine 50mg/kg 1st day, then 25mg/kg IM SID Sulfadimethoxine
Sulfamethoxazole/Trimethopr trimethoprim: 4mg/kg SQ/PO TID Sulfamethoxazole/Trimethopr
im im
Tetracycline 20mg/kg PO TID Tetracycline
Ticarcillin/Clavulanate ticarcillin: 65-100mg/kg IV TID Ticarcillin/Clavulanate
Potassium Potassium
Tylosin 2mg/kg IM SID Tylosin
Vancomycin 20mg/kg IV/IM BID Vancomycin

ANALGESICS / ANTI-INFLAMMATORIES ANALGESICS / ANTI-INFLAMMATORIES

Drug Monkey Drug
Acetominophen 6mg/kg PO TID Acetominophen
Acetominophen/Codeine Acetominophen/Codeine
Acetylsalicylic Acid 20mg/kg PO BID/TID Acetylsalicylic Acid
Buprenorphine .01-.03mg/kg IM BID Buprenorphine
Butorphanol .05mg/kg IM TID; New World: 0.02mg/kg SQ Butorphanol
QID
Carprofen 2mg/kg PO BID Carprofen
Celecoxib Celecoxib
Deracoxib Deracoxib

Dexamethasone Shock: 2-4mg/kg IV once CNS: .25-2mg/kg IM Dexamethasone

BID; Anti-inflam: .25-1mg/kg IM SID; CNS: .25-
2mg/kg IM BID
Fentanyl 7-10mcg/kg/hr IV CRI; .05-.15mcg/kg IM PRN; Fentanyl
Patch: 25mcg/5-10kg, 50mcg/10kg animal
q48-72h
Flunixin Meglimine 2mg/kg IM BID Flunixin Meglimine
Hydrocodone Bitartrate Hydrocodone Bitartrate
Hydrocortisone Sodium Hydrocortisone Sodium
Succinate Succinate
Ibuprofen 7mg/kg PO BID Ibuprofen
Ketoprofen 2mg/kg IV/IM SID Ketoprofen
Ketorolac 15-30mg/animal initially; then 10-15mg/animal Ketorolac
q8h
Lidocaine .7-1.4mg/kg IV PRN Lidocaine
Meperidine HCl 2-4mg/kg IM/IV q1/2-1h Meperidine HCl
Morphine Sulfate 1-2mg/kg IV/IM/SQ q4h Morphine Sulfate
Nalbuphine 2.5-5mg/kg IM q3-4h Nalbuphine
Naloxone .1mg/kg IV/IM/SQ PRN Naloxone
Naltrexone Naltrexone
Naproxen Naproxen
Oxymorphone .15mg/kg IV/IM/SQ q4-6h; Oxymorphone
New World: .025mg/kg IV/IM/SQ q4-6h
Prednisolone Sodium 10mg/kg IM/IV Prednisolone Sodium
Succinate Succinate
Prednisone/Prednisolone .5-2mg/kg PO Prednisone/Prednisolone
Triamcinalone .02-2mg/kg IM PRN Triamcinalone

ANESTHETICS / SEDATIVES ANESTHETICS / SEDATIVES

Drug Monkey Drug
Acepromazine 0.1-.5mg/kg IV/IM Acepromazine
Atipamezole .15mg/kg IV/IM Atipamezole
Diazepam seizure: .5-1mg/kg IV/IM Diazepam
Droperidol Droperidol
Fentanyl/Droperidol 0.1-0.3ml/kg IM; New World: 0.05ml/kg IM Fentanyl/Droperidol
Haloperidol .03-.05mg/kg IM BID Haloperidol
Ketamine 10mg/kg IM; 5mg/kg IV; Ketamine
New World: 10-15mg/kg IM
Ketamine/Xylazine Ket 7mg/kg IM; Xyl 0.6mg/kg IM New World: Ketamine/Xylazine
Ket 10-20mg/kg IM; Xyl 3.0mg/kg IM
Meditomidine 10-35mcg/kg IM Meditomidine

Midazolam .05-.1mg/kg IV(slow)/IM Midazolam

Pentobarbital adult: 25mg/kg IV slowly to effect; juvenile Pentobarbital
15mg/kg IV slowly to effect; New
World: 15mg/kg IV slowly to effect
Phenobarbital Seizure: 2mg/kg IV; 1-6mg/kg PO Phenobarbital
Propofol 2.5-5mg/kg bolus then 0.3-0.4mg/kg/min CRI Propofol

Thiamylal Sodium 15-25mg/kg IV to effect Thiamylal Sodium

Thiopental 25mg/kg IV to effect Thiopental
Tiletamine/Zolazepam 5-8mg/kg IM; New World: 1-2.5mg/kg IM Tiletamine/Zolazepam
Xylazine .5-6mg/kg IM Xylazine
Yohimbine .1mg/kg IV/IM Yohimbine

ANTIPARASITICS ANTIPARASITICS
Drug Monkey Drug
Chloroquine Phosphate 10mg/kg NGT day 1 AM; 5mg/kg NGT day 1 Chloroquine Phosphate
PM, day 2 + 3 SID
Fenbendazole 50mg/kg/day PO x3 days, repeat in 3 weeks, Fenbendazole
repeat in 3 months
Iodoquinol 12mg/kg PO TID x10-20days Iodoquinol
Ivermectin .2mg/kg SQ/PO Ivermectin
Mebendazole 50mg/kg PO BID x3d; Trichuris: 100mg/kg PO Mebendazole
BID x3d, repeat in 3wks
Mefloquine 25mg/kg NGT one dose Mefloquine

Praziquantel 5mg/kg IM/SQ/PO one dose Praziquantel

Primiquine .3mg/kg NGT SID x14d Primiquine
Pyrantel Pamoate Pyrantel Pamoate
Thiabendazole adult: 100mg/kg PO SID, infant 50mg/kg PO Thiabendazole
SID x2d
Yomesin 37.5mg PO SID x5d Yomesin

ANTIFUNGALS ANTIFUNGALS
Drug Monkey Drug
Flucytosine Flucytosine
Griseofulvin 20mg/kg PO SID; or 200mg/kg PO q10d Griseofulvin
Ketoconazole 5-10mg/kg PO BID Ketoconazole
Nystatin 100,000 units PO TID Nystatin

CARDIOVASCULAR CARDIOVASCULAR
Drug Monkey Drug
Amlodipine Amlodipine
Carvedilol Carvedilol

Digoxin maint: 2-12mcg/kg IV/IM div SID-BID; Digoxin

2-15mcg/kg PO div SID-BID
Diltiazam HCl Diltiazam HCl
Dobutamine HCl 2.5-10mcg/kg/min IV CRI Dobutamine HCl
Dopamine HCl 2-5mcg/kg/min IV CRI - renal; 5-15mcg/kg/min Dopamine HCl
IV CRI - cardio
Enalapril Enalapril
Hydralazine HCl Hydralazine HCl
Lisinopril Lisinopril
Nitroglycerin Nitroglycerin
Norepinephrine Norepinephrine
Procainamide Procainamide
Propranolol Propranolol
Quinidine Sulfate Quinidine Sulfate
Sodium Nitroprusside Sodium Nitroprusside

VITAMINS / SUPPLEMENTS VITAMINS / SUPPLEMENTS

Drug Monkey Drug
Calcitriol Calcitriol
Ferrous Sulfate Ferrous Sulfate
Folic Acid 15mcg/kg PO SID Folic Acid
Iron Dextran 10mg/kg IM q7d Iron Dextran
Vitamin B12 Vitamin B12
Vitamin C 30mg/kg IM SID Vitamin C
Vitamin D3 Vitamin D3
Vitamin E Vitamin E
Vitamin K1 1-5mg/day IM Vitamin K1
Zinc 2.5mcg/day x3d Zinc

MISCELLANEOUS MISCELLANEOUS
Drug Monkey Drug
Adequan 2mg/kg IM q3-5d x 2-3mo Adequan
Allopurinol Allopurinol
Aluminum Hydroxide Aluminum Hydroxide
Aminophylline 25-100mg/animal PO SID Aminophylline
Atropine Sulfate .02-.04mg/kg IV/IM/SQ Atropine Sulfate
Azathioprine 1-2mg/kg PO SID Azathioprine
Bisacodyl Bisacodyl
Bismuth Subsalicylate 40mg/kg PO BID/TID Bismuth Subsalicylate
Calcium Gluconate Calcium Gluconate
Cholestyramine Resin Cholestyramine Resin
Chorionic Gonadotropin Chorionic Gonadotropin
Cimetidine 10mg/kg IM/PO TID Cimetidine
Dapsone Dapsone
Denosyl SD4 (SAM-e) Denosyl SD4 (SAM-e)
Diphenhydramine HCl 5mg/kg/day TID/QID IV/IM/PO Diphenhydramine HCl
Docusate Sodium (DSS) 10-40mg PO Docusate Sodium (DSS)
Doxapram infant: 2mg/dose, adult: 2mg/kg max Doxapram
Epinephrine .1-.5mg IV/IC/IM/SQ Epinephrine
Epoetin 50-100units/kg IV/SQ 3x/wk Epoetin
Ethambutol Ethambutol

Fluoxetine Fluoxetine
Furosemide 2-4mg/kg IM TID; 1-4mg/kg IV Furosemide
Glycopyrrolate .004-.008mg/kg IM Glycopyrrolate
Guaifenesin Guaifenesin
Heparin Heparin
Hydrochlorothiazide Hydrochlorothiazide
Insulin NPH Insulin NPH
Isoniazid 5mg/kg PO SID Isoniazid

Isoproterenol .05-2mcg/kg/min IV CRI Isoproterenol

Leuprolide .3mg/kg IM q4wks Leuprolide
Loperamide .04mg/kg PO TID Loperamide
Mannitol Cerebral edema: 1.65-2.2g/kg IV over 20 min; Mannitol
Diuretic: .25-.5g/kg IV over 5-10 min
Medroxyprogesterone 150mg IM q3mos; 5-10mg PO SID x5-10d Medroxyprogesterone
acetate acetate
Megesterol Acetate Megesterol Acetate
Metformin Hydrochloride Metformin Hydrochloride
Metoclopramide .2-.5mg/kg IM SID-TID Metoclopramide
Misoprostol Misoprostol
Neostigmine .07-.08mg/kg IM q2-4h Neostigmine
Oxytocin 2units/dose PRN Oxytocin
Pancuronium .04-.1mg/kg IV PRN Pancuronium
Paromomycin 25-30mg/kg/day PO div BID Paromomycin
PGF2alpha 1mg/kg IM SID PGF2alpha
Phentolamine Mesylate Phentolamine Mesylate
Phenytoin 2.5mg/kg PO BID, increase PRN Phenytoin
Potassium Chloride 20-100mEq PO SID; .5-1mEq/kg/hr IV Potassium Chloride
Probenicid Probenicid
Prochlorperazine .12mg/kg IV/IM Prochlorperazine
Ranitidine .5mg/kg PO BID Ranitidine
Spironolactone Spironolactone
Stanozolol 5-10mg/kg IM q4-7d Stanozolol
Succinylcholine 1mg/kg IV PRN Succinylcholine

Sucralfate .5gm/dose; maintenance BID, active ulcer 4- Sucralfate

6wks QID
Sulfasalzine 10mg/kg PO TID Sulfasalzine
Terbutaline Terbutaline
Testosterone Testosterone
Theophylline Theophylline
Winstrol Winstrol

EMERGENCY EMERGENCY
Drug Monkey Drug
Aminophylline Aminophylline
Atropine Sulfate .02-.04mg/kg IV/IM/SQ Atropine Sulfate
Dexamethasone Shock: 2-4mg/kg IV once CNS: .25-2mg/kg IM Dexamethasone
BID; Anti-inflam: .25-1mg/kg IM SID; CNS: .25-
2mg/kg IM BID
Diazepam seizure: .5-1mg/kg IV/IM Diazepam
Diphenhydramine HCl 5mg/kg/day TID/QID IV/IM/PO Diphenhydramine HCl
Dobutamine HCl 2.5-10mcg/kg/min IV CRI Dobutamine HCl
Dopamine HCl 2-5mcg/kg/min IV CRI - renal; 5-15mcg/kg/min Dopamine HCl
IV CRI - cardio
Doxapram infant: 2mg/dose, adult: 2mg/kg max Doxapram
Epinephrine .1-.5mg IV/IC/IM/SQ Epinephrine
Furosemide 2-4mg/kg IM TID; 1-4mg/kg IV Furosemide
Glycopyrrolate .004-.008mg/kg IM Glycopyrrolate
Insulin NPH Insulin NPH
Isoproterenol .05-2mcg/kg/min IV CRI Isoproterenol
Lidocaine .7-1.4mg/kg IV PRN Lidocaine
Mannitol Cerebral edema: 1.65-2.2g/kg IV over 20 min; Mannitol
Diuretic: .25-.5g/kg IV over 5-10 min
Naloxone .1mg/kg IV/IM/SQ PRN Naloxone
Naltrexone Naltrexone
Nitroglycerin Nitroglycerin
Norepinephrine Norepinephrine
Pentobarbital adult: 25mg/kg IV slowly to effect; juvenile Pentobarbital
15mg/kg IV slowly to effect;
New World: 15mg/kg IV slowly to effect
Prednisolone Sodium 10mg/kg IM/IV Prednisolone Sodium
Succinate Succinate
Procainamide Procainamide
Propranolol Propranolol
Terbutaline Terbutaline
Theophylline Theophylline
 Chimpanzee Adult / Human*
2.3mg/kg IM SID
500 mg IV/IM/PO TID
13.75mg/kg PO BID
20mg/kg IV/IM/PO TID

5-10mg/kg PO SID

1gr IV/IM BID/TID/QID

25mg/kg IV/IM BID
2mg/kg IM SID
50-100mg/kg IM SID-BID
1-4 grams ÷BID-TID

20mg/kg IM BID, 50mg/kg SQ TID

16-20mg/kg PO BID
250-500mg PO BID x7-14d
150-300mg PO QID; 300-600mg IM BID/TID
2-5mg/kg PO BID

5mg/kg IM, PO SID

500mg PO BID before meal*
100mg PO QID
2-4mg/kg IV/IM BID
500mg PO SID
25mg/kg PO BID
200mg, then 100mg IV(slow)/PO BID

200-400mg IV CRI/PO

250-300mg/day IM/PO div SID-TID

1,200,000 units deep IM once*
1-20 million units per day IV/IM*
22,000 IU/kg IM SID
11mg/kg PO QID
600mg IV/PO SID
600mg rifampin/ 300mg isoniazid PO SID
1-2g/d divided in 6-12 hour intervals

Sulfa: 800mg PO BID; 15-20mg/kg/day IV div

BID-QID
20-25mg/kg PO TID-BID
200-300mg/kg/d divided evenly and given q4-
6hrs

500mg PO QID x7-10d; can give IV slow

ANALGESICS / ANTI-INFLAMMATORIES
Chimpanzee Adult / Human*
500-1000mg PO TID
.24-36mg (10-15ml) q 6hr
5-10mg/kg PO QID
NTE .3mg IM TID

2mg/kg PO BID
200mg PO SID/BID
 acute: 4mg/kg PO SID; chronic: 2mg/kg PO
SID
2mg/kg IV/IM/PO

5-10mcg/kg/hr IV CRI

5mg PO q4-6hr PRN

5mg/kg IV/IM BID

200-400mg PO TID
2mg/kg IV/IM SID
30mg PO QID or one dose of 60mg*

1-1.5mg/kg IV, max of 3mg/kg

50-150mg PO q3-4hrs or PRN
0.01-0.1mg/kg IV*
10mg IV/IM/SQ q3-6hr PRN*
15mcg/kg IV/IM/SQ PRN
3mg/kg SID
5mg/kg PO SID
1-1.5mg IM/SQ q4-6hr PRN*

10mg/kg IV

.5-2.2mg/kg PO

ANESTHETICS / SEDATIVES
Chimpanzee Adult / Human*
.5-1.0mg/kg IM/SQ/PO
150-300ug/kg IV/IM
.25-.5mg/kg IV/IM; .5-1mg/kg PO
2.5-10mg IM 30-60min before procedure
0.3ml/kg IM
0.5-5.0mg PO BID/TID*
5-40mg/kg IM

Ket 15-20mg/kg IM; Xyl 1.0mg/kg IM

30-60ug/kg IM preceded by Ketamine 2-

6mg/kg IM
1-2.5mg IV; 5mg IM*
100mg initial dose IV not to exceed 50mg/min;
150-200mg IM*

1-2mg/kg bolus followed by CRI to effect

3-5mg/kg IM; 20-80mg IV supplement

1.1mg/kg IV; 2.2mg/kg IM
0.11mg/kg IV/IM

Chimpanzee Adult / Human*

Suppression: 500mg PO q7d*
 50mg/kg/day PO x3d, repeat in 3 weeks

630mg PO TID x20days

.2mg/kg SQ/PO
100mg PO BID x3days

active: 1250mg PO once; preventative: 250mg

PO q7d
20mg/kg PO TID x1d

10mg/kg PO, repeat in 3 wks

7500-1500mg PO SID x2d (x7d for visceral
larva migrans)

Chimpanzee Adult / Human*

50-150mg/kg/day PO div QID
500mg/day PO div SID-QID
200-400mg/day PO
500K-1 million units PO TID

Chimpanzee Adult / Human*

.1mg/kg PO SID
3.125mg PO BID x2wk then inc to 6.25mg PO
BID; inc PRN
.005-.01mg/kg PO BID; .005-.01mg/kg IV PRN

.25-.35mg/kg IV slow, 180-240mg PO SID

2.5-10mcg/kg/min IV CRI
2-5mcg/kg/min IV CRI

.3mg/kg IV/PO

.25-.5mg/kg PO SID
7.5mg topically TID
.2-4mcg/min IV CRI
50mg/kg/day PO div QID
.25-1mg/kg PO TID-BID
100-200mg PO BID-TID
.3-10mcg/kg/min IV CRI

VITAMINS / SUPPLEMENTS
Chimpanzee Adult / Human*
.03mg/kg PO SID
325mg PO SID
500ug/day PO*
11-22mg/kg IM
3-5ml IV/IM/PO
4-25mg/kg PO SID
20 IU/kg PO SID
3.75 IU/kg PO SID
1mg/kg IM/PO TID
1 75mg tablet BID PRN

Chimpanzee Adult / Human*

2-3mg/kg q4d x2mo
200-600mg/day
600-1200mg PRN
10mg/kg IV
.02-.05mg/kg IV/IM/SQ
1-2.5mg/kg/day PO*
10-15mg PO PRN
30mls PO PRN
200mg/kg IV/IM/SQ
8-16g/d PO BID
5,000-10,000 USP units IM
300mg IV(slow)/IM/PO TID/QID
50mg/day PO, leprosy: 100mg/day PO
18mg/kg PO SID
25-50mg TID/QID IV/IM/PO
50-200mg PO
2mg/kg IV
.2-1mg IM/SQ; .5-10mg IV/ IC
50-100units/kg IV/SQ 3x/wk
start 15mg/kg /day PO, then 25mg/kg/day PO

.5-1mg/kg PO SID
1-2mg/kg IV/IM/PO
.004mg/kg IV/IM; 1mg PO TID
10-20mls PO q4-6h
5-10K units IV QID; 10-20K units SQ BID
1mg/kg PO SID
.25-.5units/kg/day SQ
Active TB: 30-50mg/kg PO SID x9mos;
Prophy: 300mg/day PO
.1-1mcg/kg/min IV CRI; .02-.06mg IV bolus

4mg PO PRN
.5-1.0g/kg IV

150mg IM q3mos

800mg PO SID
1500-2250mg/day PO, titrate to effect*
.4mg/kg IV(slow)/IM/PO SID-TID
5mcg/kg PO QID; 1-3mcg/kg intravaginally
0.5mg IM/SQ*
.5-1mU/min IV CRI; 5-30 units IV/SQ PRN

5-10mg IV/SQ
125mg PO TID adjust PRN*
20-100mEq PO SID; .5-1mEq/kg/hr IV
1gm PO BID x7days
5-10mg IV/IM/PO SID-TID
150mg PO BID/TID*
20-300mg/day div SID-TID
2mg PO TID-QID
0.3-1.1mg/kg IV for 2 min; 2.5-4.3mg/min CRI*

1gm PO BID

3-4g/day PO*
5mg PO SID
10-25mg IM 2-3x/wk
5mg/kg, then 2-4mg/kg TID-QID
2-4mg PO SID

Chimpanzee Adult / Human*

10mg/kg IV
.02-.05mg/kg IV/IM/SQ
2mg/kg IV/IM/PO

.25-.5mg/kg IV/IM; .5-1mg/kg PO

25-50mg TID/QID IV/IM/PO
2.5-10mcg/kg/min IV CRI
2-5mcg/kg/min IV CRI

2mg/kg IV
.2-1mg IM/SQ; .5-10mg IV/ IC
1-2mg/kg IV/IM/PO
.004mg/kg IV/IM; 1mg PO TID
.25-.5units/kg/day SQ
.1-1mcg/kg/min IV CRI; .02-.06mg IV bolus
1-1.5mg/kg IV, max of 3mg/kg
.5-1.0g/kg IV

15mcg/kg IV/IM/SQ PRN

3mg/kg SID
7.5mg topically TID
.2-4mcg/min IV CRI
100mg initial dose IV not to exceed 50mg/min;
150-200mg IM*

10mg/kg IV

50mg/kg/day PO div QID

.25-1mg/kg PO TID-BID
5mg PO SID
5mg/kg, then 2-4mg/kg TID-QID
NORMAL VALUES

CHIMPANZEE
Hematology
Infant Juvenile Adolescent Young Adult Adult Adult
Value (<1yr) (1-3yrs) (3-6yrs) (6-10yrs) (10-20yrs) (>20yrs)
RBC x106/μl 4.7-5.8 4.6-5.4 4.6-5.8 4.7-6.1
Hgb (gm/dl) 11.5-14.7 11.9-15.2 12.8-16.4 12.2-16.8
Hct (%) 35-44 36-44 37-48 37-50
MCV (fl) 68-81 75-84 76-85 76-88
MCH (pg) 22-27 25-28 25-29 25-30
MCHC (gm/dl) 32-34 32-34.4 32.5-34.6 32.1-34.1
WBC x103/μl 6.64-16.0 6.93-16.3 6.4-16.2 7.74-17.02 7.2-14.8 6.48-16.25
Mono x103/μl 0-0.6 .29-3.32 .17-3.22 .2-3.39 .41-3.61 .51-3.32
Lymph x103/μl 26.27-68.63 25.14-56.67 22.73-59.71 23.4-60.56 25.09-58.81 22.16-60.27
Neut x103/μl 2.34-8.83 1.87-10.4 2.15-10.88 2.7-11.26 2.6-10.98 1.83-11.07
Eosin x103/μl .01-.21 0-.39 .01-.4 0-.41 0-.45 0-.4
Platelets x103/μl 192-530 236-429 148-363 137-347

NORMAL VALUES

CHIMPANZEE
Serum Chemistry
Infant Juvenile Adolescent Young Adult Adult Adult
Value (<1yr) (1-3yrs) (3-6yrs) (6-10yrs) (10-20yrs) (>20yrs)
Tot bili (mg/dl) .1-.6 0-.7 .04-.76 .21-.58
ALT (U/L) 23-52 23-52 18-46 17-38 20-44 23-48
AST (U/L) 13-34 14-32 11-31 13-46 13-46 12-29
Alk Phos (U/L) 396-914 357-704 145-789 9-185 54-153 212-582
Creatinine (mg/dl) .5-.9 .5-.8 .6-1.7 .7-1.2 .8-1.3 .5-1.0
Glucose (mg/dl) 68-125 65-120 65-110 60-100 66-108 56-119
BUN (mg/dl) 7-20 10-20 9-23 7-17 9-17 7-19
Tot protein (gm/dl) 6.0-7.6 6.4-7.8 6.8-8.0 7.0-8.2 6.7-8.3 6.4-7.7
Albumin (gm/dl) 3.2-4.2 3.4-4.2 3.5-4.4 3.0-4.0 3.3-4.1 3.4-4.1
Globulin (gm/dl) 2.4-3.7 2.7-4.1 3.7-4.1 3.5-4.7 3.2-4.7 2.6-4.0
Cholesterol (mg/dl) 178-357 190-285 162-298 182-265 170-288 190-300
GGT (U/L) 9-114 1-20 13-24 10-35
Triglycerides (mg/dl) 32-135 49-124 40-108 44-154 56-164 41-104
Ca (mg/dl) 9.6-11.9 8.7-11.7 8.8-9.4 7.6-10.9 8.1-10.2 9.2-11.1
Phos (mg/dl) 4.7-7.7 1.6-6.1 1.9-5.3 1.8-4.3
CPK (U/L) 32-386 98-309 78-366 80-553
LDH (U/L) 216-553 230-435 125-408 194-435 203-503 265-480
Cl (mEq/L) 100-115 104-120 93-119 93-115
Na (mEq/L) 130-146 129-146 95-147 136-148
K (mEq/L) 2.9-6.0 3.6-4.7 3.6-4.5 2.8-4.4 3.2-4.4 3.2-4.9
HDL (mg/dl) 44-114 43-103 32-92 35-82
LDL (mg/dl) 98-242 119-195 109-174 106-209

From Lab Animal Medicine ed 2

NEW WORLD NORMAL VALUES

BOLIVIAN SQUIRREL MONKEY

Hematology Serum Chemistry
Value Value
RBC x106/μl 6.3-7.1 Tot bili (mg/dl) 0.5-0.8
Hgb (gm/dl) 12.2-13.6 Direct bili (mg/dl) 0.06-0.2
Hct (%) 38.6-43.6 ALT (U/L) 112-228
MCV (fl) 58.5-62.9 AST (U/L) 124-190
MCH (pg) 18.6-20.3 Alk Phos (U/L) 236-413
MCHC (gm/dl) 30.5-33.1 Creatinine (mg/dl) 0.8-1.0
WBC x103/μl 6.0-9.1 Glucose (mg/dl) 84-120.5
BUN (mg/dl) 31.5-45.6
Tot protein (gm/dl) 6.6-7.5
Albumin (gm/dl) 3.9-4.4
Cholesterol (mg/dl) 123-161
GGT (U/L) 21-42
Triglycerides (mg/dl) 51-95
Ca (mg/dl) 9.2-10.1
Phos (mg/dl) 4.3-7.1
CPK (U/L) 85-350
LDH (U/L) 60-149
Na (mEq/L) 145.3-154.4
K (mEq/L) 5.1-6.2
Amylase (U/l) 435-570
CO2 (mEq/l) 8.8-14.5

From Lab Animal Medicine ed 2

NEW WORLD NORMAL VALUES

OWL MONKEY
Hematology Serum Chemistry Urinalysis (Dipstick)
Value Value Value
RBC x106/μl 4.4-6.9 Tot bili (mg/dl) 0.3-1.2 Urine Specific Gravity
Hgb (gm/dl) 11.7-18.4 ALT (U/L) 10-93 Vol (ml/kg/d)
Hct (%) 36.6-52.2 Alk Phos (U/L) 0-1951 Protein
MCV (fl) 76.3-86.3 Creatinine (mg/dl) 0.6-1.5 Glucose
MCH (pg) 24.6-28.4 Glucose (mg/dl) 103-212 Ketones
MCHC (gm/dl) 31.4-33.9 BUN (mg/dl) 6-28 Bilirubin
WBC x103/μl 3.0-25.4 Tot protein (gm/dl) 7.0-9.2 Urobilinogen
Monos x103/μl 0-0.6 Albumin (gm/dl) 3.2-5.0 Occult blood
Lymph x103/μl 3.5-10.6 Cholesterol (mg/dl) 65-196 pH
Neut x103/μl 1.0-6.5 GGT (U/L) 3-47
Eos x103/μl 0-2.9 Ca (mg/dl) 8.3-11.4
Baso x103/μl 0-0.4 Phos (mg/dl) 2.5-6.3
Platelets x106/μl 205-550 Na (mEq/L) 145-165
K (mEq/L) 2.6-6.8

From Lab Animal Medicine ed 2

(Dipstick)

1.002-1.023
74.4-89.4
0-3+
0-1+
0-2+
0
0
0-4+
6-8.5
OLD WORLD NORMAL VALUES

BABOON
Hematology Serum Chemistry
Value Individual Caged Gang-caged Corralled Value Male Female
RBC x106/μl 4.27-5.69 4.07-5.79 3.76-5.61 Tot bili (mg/dl) 0.0-0.4 0.1-0.3
Hgb (gm/dl) 10.6-14.4 10.3-14.9 9.5-14.5 Direct bili (mg/dl) 0.0-0.2 0.0-0.2
Hct (%) 32.4-43.5 32.5-44.9 29.0-45.2 ALT (U/L) 29-69 4-84
MCV (fl) 70.8-83.4 72.3-85.5 70.6-84.4 AST (U/L) 29-69 18-50
MCH (pg) 23.4-27.2 23.5-28.3 22.6-28.3 Alk Phos (U/L) 0-555 0-560
MCHC (gm/dl) 31.6-34.6 30.9-33.9 30.8-34.4 Creatinine (mg/dl) 0.7-1.5 0.5-1.1
WBC x103/μl 3.1-15.5 3.2-17.0 1.8-27.4 Glucose (mg/dl) 65-101 40-136
Mono% 0-5 0-5 0-7 BUN (mg/dl) 9-19 7-20
Lymph % 6-66 10-88 0-49 Tot protein (gm/dl) 6.3-7.9 5.9-8.1
Neut % 32-90 9-87 47-100 Albumin (gm/dl) 2.3-5.1 1.8-4.6
Eosin % 0-3 0-4 0-2 Globulin (gm/dl) 2.3-4.7 2.8-4.6
Baso % 0 0-1 0-1 Cholesterol (mg/dl) 52-150 27-167
Platelets x10 /μl
6
164-521 150-550 104-566 GGT (U/L) 23-63 11-53
Triglycerides (mg/dl) 36-94 32-104
Ca (mg/dl) 8.2-10.0 7.4-10.4
Phos (mg/dl) 1.6-4.6 0.8-4.4
CPK (U/L) 70-730 0-780
LDH (U/L) 104-438 163-401
Cl (mEq/L) 90-112 89-109
Na (mEq/L) 148-154 141-153
K (mEq/L) 2.9-5.1 2.7-5.1
HDL (mg/dl) 18-102 2-98
Amylase (U/l) 117-389 45-411
Anion Gap 18-40 18-42
CO2 (mEq/l) 20-30 17-27
Iron (mcg/dl) 4-124 5-163
Lipase (U/l) 0-19 0-12

From Lab Animal Medicine ed 2

OLD WORLD NORMAL VALUES

RHESUS
Hematology
Adult Male Adult Male Adult Female Pregant Geriatric
Value Weanlings Juvenile Indoor Outdoor Indoor Female Females

RBC x106/μl 4.9-5.7 4.85-5.9 5.7-6.4 4.95-6.1 5.46-6.0 4.8-5.5 5.85-6.94

Hgb (gm/dl) 11.0-12.8 10.7-12.7 12.9-15.1 11.7-14.3 12.2-13.4 12.1-13.0 13.7-15.5
Hct (%) 34.2-39.6 32.2-38.0 42.6-49.6 35.9-44.3 38.3-42.3 34.8-38.2 41.3-47.5
MCV (fl) 66-74 61-71 72-76 67-74 67-73 68-74 67-73
MCH (pg) 20.9-24.1 19.9-23.9 21.8-24.6 22.3-24.7 21.2-23.2 23.2-25.6 21.9-23.9
MCHC (gm/dl) 31.5-33.1 32.6-34.0 29.6-31.2 31.3-33.5 31.0-32.4 33.5-34.9 32.5-33.5
WBC x103/μl 7.4-13.0 9.6-20.0 5.8-10.4 8.3-18.1 6.4-10.2 8.2-18.8 5.3-11.3
Mono x103/μl 1-5 0-8 0-4 1-5 1-7 2-6 4-10
Lymph x10 /μl
3
49-72 17-45 38-60 16-42 33-51 9-25 26-50
Neut x103/μl 25-47 46-76 34-58 54-78 43-61 68-84 39-63
Eosin x103/μl 1-3 0-4 0-4 0-2 0-4 1-3 1-7
Platelets x106/μl 3.54-6.52 4.47-6.47 2.97-4.99 3.13-4.57 3.56-6.54 2.46-4.56
Plasma Protein (gm/dl) 6.2-6.9 6.1-6.7 6.8-8.0 6.8-7.6 7.2-8.0 6.3-7.1 6.9-7.9
Fibrinogen (mg/dl) 100-300 100-300 100-300 100-300 100-300

OLD WORLD NORMAL VALUES

RHESUS
Serum Chemistry
Adult Males Adult Male Adult Female Geriatric
Value Outdoor Indoor Indoor Females
Sodium (mM/l) 144-152 147-155 146-150 145-151
Potassium (mM/l) 3.1-4.2 4.7-5.7 4.3-5.3 4.6-5.8
Chloride (mM/l) 104-112 106-110 112-116 106-114
Total CO2 (mM/l) 18-29 21-27 22-28 20-26
Anion Gap (mM/l) 15-23 rectal temp: 99.0-102.5 F
Calcium (mM/l) 8.7-10.8 9.9-10.9 9.2-10.2 9.1-10.5 HR: 120-180bpm
Phosphorus (mg/dl) 1.4-6.4 3.8-5.6 3.4-5.4 3.1-5.5 RR: 30-70/min
Creatinine (mg/dl) 0.7-1.4 1.0-1.4 0.8-1.2 0.9-1.3 gestation: 160-170 days
BUN (mg/dl) 17-29 22-30 16-22 13-21
Glucose (mg/dl) 38-74 55-89 43-71 40-72
ALT (U/l) 1-40 24-78 26-52 41-79
Alk Phos (U/l) 0-603 55-237 91-181 98-216
Total Protein (g/dl) 5.9-7.9 7.3-8.3 7.2-8.0 6.5-7.9
Albumin (g/dl) 3.2-4.1 3.8-4.8 4.1-4.7 3.4-4.4
GGT (U/l) 21-50 51-85 48-76 35-59
CPK (U/l) 88-1796 63-237 0-436 0-3003
AST (U/l) 23-68 27-45 24-38 40-88
Tot bilirubin (mg/dl) 0-0.2 0-0.3 0.1-0.3 0.2-0.4
LDH (U/l) 193-598 223-505 217-419 216-870
Cholesterol (mg/dl) 68-190 132-190 148-200 127-187
Triglyceride (mg/dl) 11-64 72-256 18-92 40-306

From California National Primate Research Center

OLD WORLD NORMAL VALUES

CYNOMOLOGUS
Hematology Serum Chemistry
Adult Females
Value Adult Males Adult Females Value Indoor
RBC x106/μl 6.31-7.55 5.74-6.84 Sodium (mM/l) 146-152
Hgb (gm/dl) 12.7-14.7 10.7-12.9 Potassium (mM/l) 4.6-6.2
Hct (%) 42.0-49.2 35.6-42.6 Chloride (mM/l) 108-112
MCV (fl) 63-69 58-66 Total CO2 (mM/l) 21-29
MCH (pg) 18.5-21.1 16.6-22.6 Anion Gap (mM/l)
MCHC (gm/dl) 29.1-31.1 25.8-32.8 Calcium (mM/l) 9.3-10.5
WBC x103/μl 7.6-10.8 8.1-13.1 Phosphorus (mg/dl) 3.8-5.4
Mono x103/μl 1-5 2-6 Creatinine (mg/dl) 0.8-1.0
Lymph x103/μl 45-71 44-64 BUN (mg/dl) 21-31
Neut x103/μl 23-51 31-51 Glucose (mg/dl) 43-69
Eosin x10 /μl
3
0-4 1-3 ALT (U/l) 39-95
Platelets x106/μl 3.30-5.30 2.21-5.59 Alk Phos (U/l) 173-343
Plasma Protein (gm/dl) 8.1-8.9 7.5-8.7 Total Protein (g/dl) 7.3-8.3
Fibrinogen (mg/dl) 100-300 100-300 Albumin (g/dl) 4.0-4.8
GGT (U/l) 43-91
CPK (U/l) 1-2692
AST (U/l) 28-58
rectal temp: 99.0-102.5 F Tot bilirubin (mg/dl) 0.2-0.4
HR: 120-180bpm LDH (U/l) 177-566
RR: 30-70/min Cholesterol (mg/dl) 134-202
gestation: 160-170 days Triglyceride (mg/dl) 35-123

From California National Primate Research Center

REFERENCES:

Physician's Desk Reference, 55th Edition, Medical Economics Company, NJ, 2001.

Hawk, CT and Leary, SL, Formulary for Laboratory Animals, 2nd Ed., Iowa Stae University Press, Ames, 1999.

Kohn, DF et al, Anesthesia and Analgesia in Laboratory Animals, Academic Press, San Diego, 1997.

Bernacky, BJ et al, Nonhuman Primates in Laboratory Animal Medicine, 2nd Ed., eds Fox et al., Academic Press,
San Diego, 2002.

Fortman, JD et al, The Laboratory Nonhuman Primate, CRC Press, Boca Raton, 2002.

Primate Medicine Department, California National Primate Research Center, University of California, Davis

Flecknell, PA ed. Laboratory Animal Anaesthesia:An Introduction for Research Workers and Technicians, Academic
Press, 1996.

Alamogordo Primate Facility, A Charles River Company, Holloman AFB, NM

National B Virus Resource Center

Viral Immunology Center
Georgia State University
50 Decatur Street
Atlanta, Georgia 30303

World Wide Web site:

http://www.gsu.edu/bvirus

National B Virus Resource Center:

Dr. Julia K. Hilliard, Ph.D. Ph: 404-651-0808
Laboratory Director Fax: 404-651-0814
email: bvirus@gsu.edu

Martin J. Wildes, MT (AAB) Ph: 404-651-0792

Laboratory Manager Fax: 404-641-0814
email: mwildes@gsu.edu

Primary Clinical Consultants:

Dr. Norman Bernstein, M.D. Ph: 540-374-3277
Dr. David Davenport, M.D. Ph: 269-341-6400
email: ddave@chartermi.net
y Press, Ames, 1999.

x et al., Academic Press,

of California, Davis

nd Technicians, Academic
ANTIBIOTICS ANTIBIOTICS
Drug Monkey Drug
Amoxicillin 6.7-13.3mg/kg IM/PO TID Amoxicillin
Amoxicillin/Clavulonic Acid 6.7-13.3mg/kg PO TID Amoxicillin/Clavulonic Acid
Ampicillin 25-50mg/kg/day IV/IM div TID-QID; Ampicillin
meningitis/septicemia 150-200mg/kg/day div
q3-4hrs
Azithromycin 40mg/kg PO SID 1st day; then 20mg/kg PO Azithromycin
SID 2-5th days
Ceftriaxone 50mg/kg IM SID Ceftriaxone
Cephalexin 30mg/kg PO BID Cephalexin
Ciprofloxacin 10mg/kg PO BID Ciprofloxacin
Enrofloxacin 5mg/kg IM/PO SID/BID Enrofloxacin
Erythromycin 35mg/kg PO TID; 15-20mg/kg/day IM BID Erythromycin
Gentamicin 2-4mg/kg IM BID Gentamicin
Metronidazole 50mg/kg PO SID Metronidazole
Oxytetracycline 25-50mg/kg PO; 10mg/kg IM/SQ Oxytetracycline

Penicillin G Benzathine 20,000-60,000 IU/kg IM SID Penicillin G Benzathine

Penicillin G Potassium 6,700-13,300 IU/kg IV/IM TID Penicillin G Potassium

Penicillin G Procaine 20,000-40,000 IU/kg IM/SQ BID Penicillin G Procaine

Streptomycin 2.5-5mg/kg IM BID Streptomycin

Sulfadimethoxine 50mg/kg 1st day, then 25mg/kg IM SID Sulfadimethoxine

Sulfamethoxazole/Trimethopr trimethoprim: 4mg/kg SQ/PO TID Sulfamethoxazole/Trimethopr

im im

ANALGESICS / ANTI-INFLAMMATORIES ANALGESICS / ANTI-INFLAMMATORIES

Drug Monkey Drug

Acetominophen 6mg/kg PO TID Acetominophen

Dexamethasone Shock: 2-4mg/kg IV once CNS: 0.25-2mg/kg Dexamethasone

IM BID; Anti-inflam: 0.25-1mg/kg IM SID; CNS:
.25-2mg/kg IM BID

Ibuprofen 7mg/kg PO BID Ibuprofen

Ketoprofen 2mg/kg IV/IM SID Ketoprofen

Lidocaine 0.7-1.4mg/kg IV PRN Lidocaine

ANESTHETICS / SEDATIVES ANESTHETICS / SEDATIVES

Drug Monkey Drug

Diazepam seizure: .5-1mg/kg IV/IM Diazepam

Ketamine 10mg/kg IM; 5mg/kg IV; Ketamine

Ketamine/Xylazine Ket 7mg/kg IM; Xyl 0.6mg/kg IM Ketamine/Xylazine

Xylazine 0.5-6mg/kg IM Xylazine

Yohimbine 0.1mg/kg IV/IM Yohimbine

ANTIPARASITICS ANTIPARASITICS

Drug Monkey Drug

Fenbendazole 50mg/kg/day PO x3 days, repeat in 3 weeks, Fenbendazole

repeat in 3 months
Ivermectin .2mg/kg SQ/PO Ivermectin

Mebendazole 50mg/kg PO BID x3d; Trichuris: 100mg/kg PO Mebendazole

BID x3d, repeat in 3wks
Praziquantel 5mg/kg IM/SQ/PO one dose Praziquantel

MISCELLANEOUS MISCELLANEOUS

Drug Monkey Drug

Atropine Sulfate 0.02-0.04mg/kg IV/IM/SQ Atropine Sulfate

Bismuth Subsalicylate 40mg/kg PO BID/TID Bismuth Subsalicylate

Calcium Gluconate 200mg/kg IV/IM/SQ Calcium Gluconate

Epinephrine 0.1-0.5mg IV/IC/IM/SQ Epinephrine

Furosemide 2-4mg/kg IM TID; 1-4mg/kg IV Furosemide

Loperamide 0.04mg/kg PO TID Loperamide

Oxytocin 2units/dose PRN Oxytocin

Paromomycin 25-30mg/kg/day PO div BID Paromomycin

PGF2alpha 1mg/kg IM SID PGF2alpha

Potassium Chloride 20-100mEq PO SID; 0.5-1mEq/kg/hr IV Potassium Chloride

EMERGENCY EMERGENCY

Drug Monkey Drug

Dexamethasone Shock: 2-4mg/kg IV once CNS: .25-2mg/kg IM Dexamethasone

BID; Anti-inflam: .25-1mg/kg IM SID; CNS: .25-
2mg/kg IM BID
Epinephrine .1-.5mg IV/IC/IM/SQ Epinephrine

Lidocaine .7-1.4mg/kg IV PRN Lidocaine

 Chimpanzee Adult / Human*
500 mg IV/IM/PO TID
13.75mg/kg PO BID
20mg/kg IV/IM/PO TID

5-10mg/kg PO SID

50-100mg/kg IM SID-BID
1-4 grams ÷BID-TID
16-20mg/kg PO BID
5mg/kg IM, PO SID
500mg PO BID before meal*
2-4mg/kg IV/IM BID
25mg/kg PO BID
250-300mg/day IM/PO div SID-TID

1,200,000 units deep IM once*

1-20 million units per day IV/IM*

22,000 IU/kg IM SID

1-2g/d divided in 6-12 hour intervals

Sulfa: 800mg PO BID; 15-20mg/kg/day IV div

BID-QID

ANALGESICS / ANTI-INFLAMMATORIES

Chimpanzee Adult / Human*

500-1000mg PO TID

2mg/kg IV/IM/PO

200-400mg PO TID

2mg/kg IV/IM SID

1-1.5mg/kg IV, max of 3mg/kg

ANESTHETICS / SEDATIVES

Chimpanzee Adult / Human*

.25-.5mg/kg IV/IM; .5-1mg/kg PO

5-40mg/kg IM

Ket 15-20mg/kg IM; Xyl 1.0mg/kg IM

1.1mg/kg IV; 2.2mg/kg IM

0.11mg/kg IV/IM

Chimpanzee Adult / Human*

50mg/kg/day PO x3d, repeat in 3 weeks

.2mg/kg SQ/PO

100mg PO BID x3days

20mg/kg PO TID x1d

Chimpanzee Adult / Human*

.02-.05mg/kg IV/IM/SQ

30mls PO PRN

200mg/kg IV/IM/SQ

.2-1mg IM/SQ; .5-10mg IV/ IC

1-2mg/kg IV/IM/PO

4mg PO PRN

.5-1mU/min IV CRI; 5-30 units IV/SQ PRN

20-100mEq PO SID; .5-1mEq/kg/hr IV

Chimpanzee Adult / Human*

2mg/kg IV/IM/PO

.2-1mg IM/SQ; .5-10mg IV/ IC

1-1.5mg/kg IV, max of 3mg/kg