Professional Documents
Culture Documents
Non-Communicable Diseases
Non-Communicable Diseases
Non-Communicable Diseases
Diseases
Noncommunicable (noninfectious) diseases
• Illnesses that cannot be transmitted from one person to
another.
• agent-the population and their characteristics
• host-the factors that may cause disease
• environment - the physical environment, behaviors,
cultural factors, physiology, and other external factors that
impact disease.
Double Burden Of Disease
A tumor is said to be
benign when its gross and
microscopic appearances are
considered relatively innocent,
implying that it will remain
localized, will not spread to other
sites, and is amenable to local
surgical removal
Malignant Tumors
• Referred to as cancers, derived from the Latin word-crab
• Malignant tumors can invade and destroy adjacent structures and spread to distant sites
(metastasize) to cause death.
• Sarcomas (Greek sar =fleshy)
• Malignant tumors arising in solid mesenchymal tissues
• Ex. fibrosarcoma, chondrosarcomawhereas those arising
• Leukemia/ lymphomas
• from blood-forming cells .
• Carcinomas
• Malignant neoplasms of epithelial cell origin
• Derived from any of the three germ layers
• cancers arising in the ectodermally derived epidermis
• the mesodermally derived renal
• tubules, and the endodermally derived lining of the gastrointestinal tract
Metastasis
Defined by the spread of a tumor to sites that are physically
discontinuous with the primary tumor, and unequivocally marks a
tumor as malignant, as by definition benign neoplasms do not
metastasize.
Hallmarks of Cancer
Tumor Markers