Power Electronics in Biomedical Applications

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15th International Power Electronics and Motion Control Conference, EPE-PEMC 2012 ECCE Europe, Novi Sad, Serbia

Power electronics in biomedical applications


– an overview
B. Grzesik1, M. Stepien2
Silesian University of Technology, Gliwice, Poland, 1boguslaw.grzesik@polsl.pl, 2mariusz.stepien@polsl.pl

Abstract — The paper is focussed on power electronics in will function. It is possible to list some categories of
biomedical applications. The introductory part delivers anatomy and physiology: some information of cell
definitions of power electronics. Then there are the technical structure, heart and circulatory system, central nervous
demands concerning power electronics in biomedical system, muscle operation, respiratory system, body
applications. Finally the biomedical application together temperature together with heat exchange and
with examples are discussed. Closing part of the paper reproduction system.
embraces biomedical applications seen from the point of An overview of the power electronics in biomedical
view of power electronics. applications focuses on selected devices and systems.
Keywords — artificial heart, biomedical engineering,
transcutaneous energy transfer. II. BIOMEDICAL APPLICATIONS
There are many power electronics system that are used
in biomedical engineering. One can be seen them from
I. INTRODUCTION the point of view of power electronics, namely they are
Power electronics [1], is a part of technology that is DC, AC supplying sources, generators, wireless energy
devoted to control of energy flow between sources and transfer devices. It is possible to split these applications
loads, which generally have different parameters, and the into three groups. The first one operates without contact
control is realized by switching electronic devices. In with human body, e.g. X-ray based diagnostic systems.
many cases loads are associated with its specific The second group are systems that operates being
characteristics and parameters. In many cases, the load permanently implanted in the patient's body; the
parameters arise from specific processes that require a pacemaker is an excellent example. The third group is
power supply. Transcutaneous energy transfer (TET) for such that operates having its part implanted in human
implantable artificial heart could be a good example. The body; totally implanted artificial heart is the example of
inverter which supply external coil sees R-L circuit which this group (in this case the system operates like TET
changes its parameters due to variation of position of (Transcutaneous Energy Transfer by means of contactless
external coil in relation to internal one. It means that magnetic coupling).
operation of the inverter should be made insensitive to It is possible to specify the following medical
variations of external coil position. The inverter should application that are containing power electronics
adjusted to variation of external coil position. subsystems. They are: i) X-ray based diagnostic systems,
The efficiency of power electronic converters is very ii) magnetic resonance imaging (MRI), iii) medical
high. This results from low power losses what is magnetic fields (MMF), vi) nerve and muscle stimulators,
important for long time of usage when the medical v) prostheses (artificial heart and exoskeleton in it), vi)
equipment is supplied from battery or the equipment is artificial heart pump combined with BLDC machine with
implanted in the body of patient (as it takes place in case levitating rotor, vi) batteries for supplying totally
of artificial heart). The following features are expected implanted systems, vii) medical magnetic systems, viii)
from medical equipment and from power electronics electro-acupuncture.
converters: i) the highest possible efficiency, ii) the The X-ray tube operating in diagnostic system needs
highest reliability (that means it should perform assumed the supply of 30 kV to 150 kV and 1 mA to 1 A for
functions under given conditions for specified period of producing pulses 1 ms to 1 s. Contemporary supplying
time), iii) their casing of the converter itself, controls, systems operate like DC-DC SMPS that can be easily
transformers, batteries and external insulation of the controlled. HV transformer is needed. X-ray system is
cables that connect the pieces of biomedical application, equipped with devices for focus in x-ray beam, standard
iv) they has to be of light weight and usually small electromagnetic coils, capillary lenses [9], [10] and self-
volume, v) the biomedical applications has to ensure focused cathode [11].
compliance with regulations concerning EMI/EMC, vi)
the highest possible immunity to electric and magnetic MRI (Magnetic resonance imaging) [12] is the
field in the specified frequency range and vii) the technology that uses magnetism, radio technology and
temperature of apparatus, especially that which is in computer analysis to gain images of human body
contact with human tissue, should be kept within structures. It contains the following parts: i) magnet, ii)
acceptable limits, viii) the highest possible gradient coils, iii) RF coil, iv) gradient amplifier, v)
biocompatibility. gradient pulse programmer, vi) RF detector, vii) RF
source, pulse programmer. The magnet generates main
Designing biomedical apparatus the purposes of use DC magnetic field of 0.2 T to 2 T. It is made of
should be kept in mind. In short, one can be aware what superconductor wire. It is kept in liquid helium (~4.2 K).
is the category of anatomy and physiology in which it RF source operates at about 60 MHz. Magnet coils are

978-1-4673-1972-0/12/$31.00 ©2012 IEEE LS5a.1-1


controlled by power converters. The MRI technology is task as it the magnetic field density is relatively low. The
extremely interesting for power electronics community field can be confined to needed region by means of ferrite
from the theoretical as well as from application point of screens. Also the variable magnetic fields do not cause
view. The coils system has to be analyzed with FEM trouble as the frequencies and magnetic field have
software. The general structure of MRI is given in Fig. 1. relatively low values. MMF can be used in broad range of
Medical Magnetic Fields (MMF) or Medical Magnetic cases. The results of clinical trials confirming beneficial
Therapy (MMT). This is the method of healing and therapeutic effect of magneto-therapy and magneto-
stimulating which is implemented by means of permanent stimulation. As therapeutic example one can give the
one or/and alternative magnetic fields [7], [8]. The fields treatment of infectious wounds, burns and varicose
used in magnetotherapy range from 0.1 mT to 20 mT at ulcers. It is even claimed that it can help broken bones
frequencies lower than 100 Hz. The fields used in heal faster. Magnetic stimulation induces current in
magneto-stimulation are from 1 pT to 100 μT AT certain parts of the patient body and made them more
frequencies ranging from several Hz to 3000 Hz [7]. It is active.
necessary to notice that permanent neodymium magnets The next example of biomagnetic application of power
have ~1.6 T maximal saturation value. The “equipment” electronics is artificial heart [3], [13]. The scheme of
in the case of permanent magnetic field is very simple. artificial heart is given in Fig. 2.
The only problem can be faced when the magnetic field
should be focused on certain place of patient but it is easy
shield
magnet
gradient coils
RF coils

measuring RF coils
table
gradient coils
magnet

gradient RF detector
amplifier
& gradient
prorammer digitizer
recording
pulse
programmer RF amplifier
computer
monitor

RF source

Fig. 1. General structure of MRI

Fig. 2. Scheme of artificial heart.

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Fig. 3 Synchronous rectifier

Fig. 4. Prototype of artificial heart.

The main problem is to deliver energy to the pump of energy delivered by coupled coils. The synchronous
artificial heart from outside the patient. There are two Mosfet rectifier is the best solution. The system of
methods. The first is when energy is transfer by a cable artificial heart contains internal battery which supplies
through a hole made in the skin. This is dangerous pump/motor when the energy is not delivered via coupled
because of possible infectious disease. This disadvantage coils (for instance when a patient carries out hygiene).
is avoided in the second way of power transmission. The internal battery charged also with the highest
There is no need for hole in the patient skin. The energy possible efficiency so application of soft switching
is transferred via coupled coils, one is put outside patient charger is reasonable. The converter that supplies energy
positioning closely to his/her skin. The second coil is taken from external battery has to proper features, like
implanted subcutaneously. well defined frequency, high efficiency and EMI below
The coupled coils contribute with their 25% of power accepted level. Class E inverter meets these requirements.
loss with the overall efficiency of transcutaneous energy It is necessary to underline that application of
transfer operate at efficiency of about 80%. The synchronous rectifier (Fig. 3) gives significant reduction
efficiency of the coupled coils can be raised by means of of power losses.
proper dimensions, using litz wire and application of The next group of application are electromechnical
ferrite cores for external and internal coil. The latter devices like prostheses, surgical robots and exoskeleton-
raises the value of couple coefficient which in turn like systems [2]. These applications embrace power
reduces power loss in the coils. The power loss is electronics and electrical drivers being in close relation
important as the higher it is the higher temperature is with contemporary range this discipline.
generate inside body of the patient. The second in row is
Discussing power electronics in biomedical applications
the pump together with motor that drives pump. The
special demand concerning the pump, which rotor is it is necessary to take into consideration of: i) laser
integrated with the rotor of the motor should operate systems (cascade infrared (Quantum Cascaded Laser) in
being levitated in magnetic field. It is not allowed to rub it), ii) ultrasonics .iii) batteries iii) contemporary
the rotor against the stator as it leads to destruction of transistors SiC, etc.
blood cells. The task of design of such pump integrated
with the motor is a serious one. The solution should be III. CONCLUSION
based on hybrid solution: passive and at the same time The applications of power electronics in biomedicine is
active one. This means that not only the design of the important although they are usually not being a subject of
pump / motor is a difficult task but the control of the intensive research activity of power electronics
levitation process is also difficult. Other parts of such community.
artificial heart also are important as they should generate
minimal power losses. They are rectifier that converters Introducing the subject of power electronic in

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biomedical application to power electronic conferences [6] Andra W., Nowak H., “Magnetism in Medicine”, Wiley - VCH
leads to an intensification of both, power electronics and 1998
biomedical applications. It is a valuable initiative. [7] Sieron A. (ed), “Application of magnetic field in medicine”,
Alpha-press, 2002
[8] Sieron A., “Spatial magnetic field - a new form of therapy”, Acta
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