Scribd Logo
Upload

Welcome to Scribd!

  • 11 views

    Risk Factors:: Has Not Spread To The Nearby Lymph Nodes or Elsewhere

    Uploaded by

    GENESIS ANGNEN
    Age, smoking, alcohol, and genetic mutations can cause uncontrolled cell division leading to adenomatous or serrated polyps. Further mutations in genes like p53 and k-Ras can cause malignant transformation into colorectal cancer. Colorectal cancer stages range from early stage cancers contained in the colon wall to later stages where the cancer has spread to lymph nodes or distant organs like the liver.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content

    You might also like

    Risk Factors:: Has Not Spread To The Nearby Lymph Nodes or Elsewhere

    Uploaded by

    GENESIS ANGNEN
    11 views2 pages
    Age, smoking, alcohol, and genetic mutations can cause uncontrolled cell division leading to adenomatous or serrated polyps. Further mutations in genes like p53 and k-Ras can cause malignant transformation into colorectal cancer. Colorectal cancer stages range from early stage cancers contained in the colon wall to later stages where the cancer has spread to lymph nodes or distant organs like the liver.

    Original Description:

    pathophy

    Original Title

    pp v1

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Age, smoking, alcohol, and genetic mutations can cause uncontrolled cell division leading to adenomatous or serrated polyps. Further mutations in genes like p53 and k-Ras can cause malignant transformation into colorectal cancer. Colorectal cancer stages range from early stage cancers contained in the colon wall to later stages where the cancer has spread to lymph nodes or distant organs like the liver.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    11 views2 pages

    Risk Factors:: Has Not Spread To The Nearby Lymph Nodes or Elsewhere

    Uploaded by

    GENESIS ANGNEN
    Age, smoking, alcohol, and genetic mutations can cause uncontrolled cell division leading to adenomatous or serrated polyps. Further mutations in genes like p53 and k-Ras can cause malignant transformation into colorectal cancer. Colorectal cancer stages range from early stage cancers contained in the colon wall to later stages where the cancer has spread to lymph nodes or distant organs like the liver.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 2

    Risk factors:

    Age
    Smoking and Alcohol

    Sporadic Gene Mutation

    APC Gene Mutation DNA Repair Gene Mutation

    Uncontrolled division of cells division and Fast Epithelial Division

    Adenomatous Polyp
    Serrated Polyp

    P53 gene and k-Ras Mutation

    Malignant Transformation

    mass with invasion of nearby tissue

    May ulcerate , obstruct


    friable fungating mass lesion which occupied and bleed
    almost 50% of the luminal diameter seen on
    Colonoscopy
    Hematochezia

    Colorectal Cancer Stages


    Pale palpebral conjunctiva
    Stage 0: In situ low hemoglobin hemtocrit

    Stage 1:Beyond the mucosa


    No Lymph nodes

    Stage 2: mass grown through


    the wall . has not spread to the
    nearby lymph nodes or
    elsewhere 
    Several well-defined hypodense
    foci seen in the liver on CT SCAN
    Stage 3: grown through the
    muscle layers, has spread to
    lymph nodes, no distant Epigastric pain, non-radiating
    metastasis

    Stage 4: metastatic, reached


    distant organs Metastasis via the portal Increased AST, ALT, ALP
    circulation

    You might also like