DRUG DATA CLASSIFICATION MECHANISM OF INDICATIO CONTRAINDICATION ADVERSE REACTION NURSING RESPONSIBILITIES

ACTION N

Generic Paracetamol is part Paracetamol ha •caloric Paracetamol Adverse Avoid the use of other
Name:Paracetamo of the class of drugs s a central Mild pain undernutrition. Reactions. over-the-counter
l known as analgesic effect or Fever •acute liver  Paracetamol preparations. They may
"aniline analgesics" that is mediated failure.  only rarely causes contain acetaminophen,
Trade Name: ; it is the only such through gastrointestinal problems and serious overdosage
•liver can occur. If you need an
Tempra drug still in use activation of or allergic skin reactions
problems. over-the-counter
today. It is not descending . Blood dyscrasia (e.g.
considered serotonergic •severe thrombocytopenia), preparation, consult your
an NSAID because pathways. renal impairment. methaemoglobinemia, health care provider.
it does not exhibit Debate exists •a condition and hemolytic anemia are Report rash, unusual
significant anti- about its primary where the body is very rare. A minority of bleeding or bruising,
inflammatory activity site of action, unable to maintain the subjects with so-called yellowing of skin or eyes,
(it is a weak COX which may be adequate blood aspirin intolerance changes in voiding
inhibitor). inhibition of flow called shock. responds patterns.
prostaglandin •acetaminop to paracetamol with Patients should be
(PG) synthesis or hen overdose. bronchospasms. cautioned not to take any
through an active other products
•acute
metabolite containing paracetamol a
inflammation of the
influencing nd they should read the
liver due to
cannabinoid label of all other
hepatitis C virus.
receptors. medication carefully to
ensure that it does not
contain paracetamol. -
Make sure patients are
aware they must not
exceed the recommended
dose.
DRUG DATA CLASSIFICATION MECHANISM OF INDICATION CONTRAINDICATION ADVERSE REACTION NURSING
ACTION RESPONSILITIES
Generic Name: Antibiotic
Ceftazidime cephalosporin (3rd Central Nervous •Contraindication to •pain, swelling, •If administered
gen) Ceftazidime is system Infection patients with burning, or irritation concomitantly with
Trade Name: bactericidal allegies to Penicillin around the IV another antibiotic,
in action exerting and cephalosporin. needle; nausea, monitor renal
Fortaz, Tazicef
its effect by vomiting, diarrhea,  function and report
inhibition of •Ceftazidime is stomach pain; or. if symptoms of
enzymes contraindicated in vaginal itching or dysfunction appear
responsible for patients with discharge. (e.g., changes in
cell-wall synthesis, cephalosporin hyp •comprehensive I&O ratio and
primarily penicillin ersensitivity or interactions pattern, dysuria).
binding protein 3 cephamycin hyper •rash Be alert to onset of
(PBP3). A wide sensitivity. rash, itching, and
range of gram- Ceftazidime should dyspnea.
negative be used cautiously
organisms is in patients
susceptible with hypersensitiv
to ceftazidime in ity to penicillin. The
vitro, including structural similarity
strains resistant to between
gentamicin and ceftazidime and
other penicillin means
aminoglycosides. that cross-reactivity
can occur.
 DRUG CLASSIFICATION MECHANISM OF INDICATION CONTRAINDICATION ADVERSE REACTION NURSING
DATA ACTION RESPONSIBILITIE
S
It is a peptide hormone Oxytocin increase It is indicated for (1) The induction or Slow heart
GENERIC and a heterodetic cyclic s the sodium induction of labor in continuance of labor rate. Monitor
NAME: peptide. permeability of patients with a with oxytocin shoul maternal BP
Fast heart
OXYTOXI  Oxytocin is an uterine myofibrils, medical indication fo d be avoided when and pulse
rate.
N Oxytocic. indirectly r the initiation of the following frequently and
The physiologic effect stimulating labor, such as Rh conditions or Premature fetal heart rate
of oxytocin is by contraction of the problems, maternal situations are ventricular continuously
TRADE
means uterine smooth diabetes, pre- present: evidence of complexes and other throughout
NAME: irregular heartbeats
of Increased Uterine muscle. The uterus eclampsia at or near fetal distress, fetal administration.
PITOCIN (arrhythmias)
Smooth responds term, when delivery is prematurity, This drug
Muscle Contraction to oxytocin more in the best interest of abnormal fetal Permanent occasionally
or Tone. The readily in the mother and fetus or position (including central nervous causes water
chemical classification  presence of high when membranes are unengaged head), system (CNS) or intoxication.
of oxytocin is Oxytocin estrogen prematurely ruptured placenta previa, brain damage, and Monitor patient
. concentrations and and delivery is uterine prolapse, death secondary to for signs and
with the increased indicated; vasa previa, suffocation. symptoms
duration of cephalopelvic (drowsiness,
Neonatal seiz
pregnancy. disproportion, listlessness,
ure.
cervical cancer,  confusion,
Neonatal headache,
yellowing of skin or anuria) and
eyes (jaundice) notify phy-
Fetal death. sician or other
health care
professional if
they occur.
 DRUG DATA CLASSIFICATION MECHANISM OF INDICATION CONTRAINDICATION ADVERSE REACTION NURSING
ACTION RESPONSIBILITIES
GENERIC NAME: Omeprazole oral
OMEPRAZOLE Belongs to Pump in Mechanism of capsule is used Contraindicated The most common Advise patient to
hibitor  Action to reduce the  in patients with adverse avoid alcohol and
TRADE NAME : Omeprazole is amount of acid in known reactions reported foods that may
PRILOSEC a proton pump your stomach. It's hypersensitivity (i.e., with an cause an increase
inhibitor. used to treat to any component incidence rate ≥ 2%) in GI irritation.
It inhibits the gastric or of the formulation. from Instruct patient to
parietal cell H+ / duodenal Treatment PRILOSEC-treated report bothersome
K+ ATP pump, the ulcers, gastro with omeprazole patients enrolled or prolonged side
final esophageal  may mask the in these studies effects, including
step of acid reflux disease symptoms of other included headache  skin problems
production. In (GERD), erosive gastric disease. (6.9%), abdominal (itching, rash) or
turn, omeprazole  esophagitis, and Caution should be pain (5.2%), nausea GI effects
suppresses gastric hypersecretory exercised in (4.0%), diarrhea (3.7%) (nausea, diarrhea,
basal and conditions. This patients with , vomiting (3.2%), and vomiting,
stimulated acid drug is also used hepatic flatulence (2.7%). constipation,
secretion. to treat stomach impairment. heartburn,
infections caused flatulence,
by Helicobacter abdominal pain).
pylori bacteria.
DRUG DATA CLASSIFICATIO MECHANISM OF ACTION INDICATION CONTRAINDICATION ADVERSE NURSING
N Mefenamic acid has REACTION RESPONSIBILITIES
GENERIC analgesic, anti- Mefenamic acid Mefenamic acid is
NAME : Mefenamic inflammatory, and is used for the contraindicated in Mefenamic Acid
Mefenamic acid, an antipyretic properties. short-term patients with salicylate  Adverse  Assess
acid anthranilic The mechanism of actio treatment hypersensitivity or Reactions. patients who
TRADE NAME acid n of mefenamic acid, of mild to NSAID Dependent on develop
derivative, is like that of other NSAIDs, moderate pain fro  hypersensitivity who the dose and the severe
Ponstan, Po a member of is not completely m have duration of diarrhea and
nstel the fenamate understood but involves various conditions. experienced asthma, treatment, vomiting for
group inhibition of It is also used to urticaria, or other mefenamic acid dehydration
of nonsteroid cyclooxygenase (COX-1 decrease allergic reactions after frequently and
al anti- and COX-2). Mefenamic  pain taking aspirin or other causes diarrhea electrolyte
inflammatory acid is a potent inhibitor  and blood loss NSAIDs. Severe, rarely . Long-term imbalance.
drugs (NSAI of prostaglandin  from menstrual fatal, anaphylactoid treatment can  Lab tests:
Ds). It synthesis in vitro periods. reactions to mefenamic lead to enteritis With long-
exhibits anti- Mefenamic acid have been or colitis term therapy
inflammatory, acid is known as a reported in such (sometimes with (not
analgesic, nonsteroidal patients. steatorrhea). recommende
and anti-inflammatory  The drug can d) obtain
antipyretic drug (NSAID). also periodic
activities. cause nausea, complete
Similar to vomiting and blood counts,
other NSAIDs upper abdomina Hct and Hgb,
, mefenamic l pain. and kidney
acid function tests.
inhibits prost
aglandin synt  Discontinue
hetase drug
promptly if
diarrhea, dark
stools,
hematemesis,
ecchymoses,
epistaxis, or
rash occur
and do not
use again.
Contact
physician.