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LET’S “TALK” ABOUT

GENETICS!
3 EXPERT TALK TRANSCRIPTS
from HEALTHMEANS
CONTENTS
Enjoy learning from these expert Hidden Genetic Switches We’re happy that you’re taking
talk transcripts pulled James Maskell with Mark Sisson time to learn about living a
from the thousands of talks Click here to watch this interview! healthier and happier life, and we
in our HealthMeans library! hope you’ll make us a regular part
Genetic Defects of that journey!
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Alicia Lynn Diaz, MA, AHP with
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Hidden Genetic Switches
James Maskell with Mark Sisson
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The purpose of this presentation is to convey information. It is not intended to
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this way of living continues to be on Now what’s the big deal, you say.
the rise. Well, there are more and more of
these foods that we can start to
I think the other thing that I’m include back into our way of eating.
seeing is that there’s been a shift. I think that there’s a been little bit
James: Hello! And welcome back
The pendulum swings back a little of a resurgence of or a reevaluation
to The Evolution of Medicine™
more now so that the original of legumes for a lot people who
Summit. We are on Friday. It is the
hard core Paleo, eliminate this, say, “Well, wait a minute. Was
Paleo day. And we are talking about
eliminate that, eliminate this and there really a reason to completely
the evolution of nutrition. And we
then became sort of seen as a exclude all legumes from one diet
are very excited to bring someone
elimination diet, has given way to in the event that you didn’t have
to the Evolution of Medicine™
a more gentle approach which is a gut dysbiosis?” And I think that
summit who was a big supporter
more of an inclusion diet which is, the consensus has been there are
of it last year and has made a
“Okay, these are the things that we a lot of people who can probably
big difference and impact on my
shouldn’t be eating. But there are a consume some amount of legumes.
life and the life of my partner in
lot of things that we may be left on
the evolution of medicine, Gabe
the table, literally and figuratively, So now you add back some
Hoffman. Mark’s Daily Apple
that we could be eating.” resistant starch, some legumes. You
founder, Mark Sisson. Welcome,
recognize that there are moments
Mark.
The whole resistant starch in time when you can take a bite or
discussion just in the last two years two of something that would have
Mark: Thanks, James. Good to be
has now brought back the concept been not on the Paleo list and all of
here.
of potato salad, for instance. For a sudden it’s okay. If you know how
the longest time anybody who was your body reacts to it, and it’s okay,
James: Great to have you on The
Paleo would say, “Well, there’s no and you’ve done that experiment.
Evolution of Medicine™ Summit.
way I’m going to eat potato salad.
Last year we had a whole day
Potatoes have a high glycemic So we start to see that this way of
focused around the evolution of
index. There’s mayonnaise. It has eating that certainly continues to
nutrition and evolutionary concepts
nasty oil. So there’s no way I can revolve and evolve around real food
within nutrition. Obviously Paleo
ever eat potato salad.” but is now one of inclusion rather
continues its rise as more and more
than exclusion. It’s now one of okay,
popular and just wanted to start
And then the resistant starch let me experiment with all of the
by getting your thoughts on what
movement discovered that when wonderful things I can eat to add
you see happening in the world of
you take a potato and you heat it to just the variety that makes life so
nutrition and why some of these
up, boil it, and then you cool it for enjoyable. And that’s what really a
concepts continue to become more
a period of time, those glucose lot of people have seen is that the
and more interesting and powerful.
molecules recrystallize into a sustainability of one’s sticking to this
resistant starch, which can help program is the most important and
Mark: Well, number one, it works.
feed the healthy bacteria in your critical aspect of it.
We’ve got now a solid eight or nine
gut. And this is my initial shameless
years of user experiences where
plug. I just introduced a mayonnaise If it weren’t sustainable, if it were
people are seeing the kind of
that’s made with avocado oil and onerous and you felt like you were
results that they never saw before
organic eggs. So now you can making sacrifices at every meal,
trying other modalities. So that’s
combine a healthy mayonnaise and that would be a very difficult way
really probably the number one
potato and make a potato salad. to convince people to eat. But the
reason that this way of eating and
fact that you can make every single Mark: Yea, I mean if people can turned on or off by the activities
bite of food you eat enjoyable and just understand that each of us that we choose, whether it’s the
healthful, by the way, that’s a huge has within us a DNA recipe that food we eat.
calling card for this way of eating. wants to design and build a strong,
And I think it continues to impress fit, healthy body. And the recipe High omega-6 oils can turn on pro-
on a number of people who crafted over 2.6 million years of inflammatory switches which is
considering and are on the fence, human evolution is basically one not necessarily a good thing. Too
and thinking about it. Now you start that expects certain inputs. much sugar can turn on some of
to open the door and say, “Well, the switches that would predispose
there are a lot of things that you Genes are ready, willing, and able us to being a type II diabetic and
can eat that you maybe assumed to rebuild, renew, regenerate, increase insulin resistance. On the
you couldn’t eat.” recreate us every minute of every other hand, we can discover these
day. It’s not like the genes stop switches that allow us to build
James: Yeah, it’s an exciting time working when we’re born. Our muscle very efficiently and quickly
because I completely agree with genes are constantly responding to with the least amount of pain and
you that is if people started reading signals they get from outside. And suffering and the least amount of
Paleo and got into it, they would we’re the ones that provide those time spent in the gym.
see that they were sort of maybe signals. So this genetic recipe that
in their minds setting themselves we have allows us to turn on genes So there’s a certain high-tech
up for a life of misery. It’s either that build muscle, to turn on genes element to this of selecting what we
good health or misery, and you that burn fat efficiently, to turn want from our lives and then being
had to make a choice because all on genes that improve our mood, able to literally control the outcome,
of those foods that humans have that improve our ability to combat to a certain extent, through the
been eating at least for the last disease. amount of sleep we get, the amount
10,000 years if not before that, like of sun exposure we get, how we
a potato, is an interesting now that’s But we also have genes that can choose to do our workouts, the
coming full circle. cause us to store fat. And this is types of foods we eat, when we
part of our heritage in evolution. eat, when we don’t eat. It boggles
Maybe as towards the end of the It was appropriate that in certain the mind when you really start to
interview, I’ll ask you where you circumstances humans could understand the genetic science and
think this is going next. store extra calories as fat and you understand the power of the
use it as fuel during periods of epigenome.
But I really wanted to get into as famine. We have genes that turn
sort of like what I feel is the content on inflammatory processes. James: So, Mark, I think obviously
that I love hearing from you and And if you’re in a life or death food is a huge part of this. And
I feel like I’d love to share with all situation, inflammation is actually maybe we could start there. But I
of our listeners, we’ve had some a good thing in the short-term. do want to talk about some of the
conversations. And I’ve seen you It’s a process that the body uses other areas outside food because
blog about it. And obviously the to combat either an invader or a one of the things I really appreciate
functional medicine movement traumatic injury. about Mark’s Daily Apple is it’s not
has been all over this really looking all food. There are other areas that
at food as a way of stimulating But if you turn those same you’re talking about that do affect
genetics and the connection of inflammatory genes on over a long this genetic expression.
food to genetic expression through period of time, day in and day out
epigenetics. and cause what we call some form So if you had to boil down your
of systemic inflammation then there message of what you’ve seen work
And it seems to be one of the can be negative consequences to with yourself and all the feedback
strongest ways in which we can that which result in heart disease that you’ve got from all the people
influence our genetics and actually or cancer or type II diabetes or who read the blog and connect
create good health. So I’d love for arthritis or a host of other issues. with it, what are some foundations
you to share some of your thoughts So we have this incredible power for people who may be new to this
on that because I really feel like at our fingertips to selectively turn to be able to jump on this in the
you’ve got this down, and I think it’s on or off some of these hidden easiest way possible and to make
an important conversation to have. genetic switches. And it’s been my the lifestyle that you’ve blogged
life’s work to discover what those about and that is keeping people
switches are and how they’re best healthy?
What is the accessible, basic carbohydrates that are not present eating strategy. So the elimination
principles that you would in the form of a plant cell and of those toxic foods would be
recommend? therefore they’ve been refined. number one.

Mark: Yea I mean with anybody And it looked at the difference And then the number two strategy
I’d recommend the first thing you across the board in all sorts of that I would like people to start
do is look at all the sugar that’s blood sugar parameters and weight to, a goal maybe, if you will, is to
in your diet and do what you can gain parameters between acellular start to get really in touch with
to eliminate it. For a lot of people carbohydrates (those that had been your appetite and understand that
it’s surprising when they do the processed) versus those that are in once you cut back on the sugars
accounting and they find out that real food (that are present in cells and starches and the carbohydrate
they’re having some sort of cereal of the plants from which they were excess and overload, once you
for breakfast, a juice throughout the originally derived). start to become good at burning fat
day. once again…We literally talk about
So I look at, backing up, so get rid reprogramming the genes to derive
They might be snacking on other of all sugar and do what you can to most of your energy from stored
juices and sometimes soft drinks or cut back processed carbohydrates. body fat.
sweetened teas. Certainly look at And in many cases that’s also
desserts. But if you do the analysis going to include even whole grains Once your body has made this
and you see how much sugar you’re because you’ll find whole grains adjustment and it takes about
consuming, the first thing that you in breads and whole grain cereals twenty-one days, start to get in
need to really take a look at is, and things like that. And they do touch with your appetite. Start
“Okay, I need to cut way back on convert to glucose, which is sugar to notice. If you wake up in the
the sugar.” And my admonition is in the bloodstream pretty rapidly, morning and you’re not hungry, then
do what you can to eliminate it as pretty quickly. And as a result, maybe don’t eat until you’re hungry
entirely as possible. So that’s sort of they tend to raise insulin which is, because if you’re not hungry that
the first, basic element. among many other things, is a fat means your body’s getting plenty of
storage hormone. So the more you energy from your stored body fat.
Now you go, Well, what am I going can mitigate the release of insulin And it’s doing well with that.
to do if I don’t have sugar and how as a result of a sugar or glucose
am I going to assuage my sweet overload, the better off you’ll be And I’m suggesting that if you’re
tooth?” Well, berries and some over a lifetime. not hungry then why eat? This is a
kinds of fruit would be allowable skill and a strategy that we develop.
in this eating style. And you’d And then finally in some cases some And as you get in touch with your
find pretty quickly that a bowl of physicians are now considering hunger, when you do eat a meal,
blueberries with some whipped these most insidious of all would be start to ask yourself, “Well, this is
cream on them as a dessert is the industrial seed oil so that would great. Every bite of the food tastes
probably better tasting in many be those polyunsaturated fatty acid great. But am I hungry for the next
cases than a piece of pie with a oils, the liquid oils that you find on bite?” Not, “Am I full?” But,
beige crust and whatever no matter the shelf, the corn oil, soybean oil,
how sweet it is. So there are some canola oil, things like that. So those “Am I truly hungry for the next
replacements there. are the big three. And if you did bite?” And if you’re not, get in a
nothing but get rid of those, you’d position where you can push the
The next thing I do is look at the be 85% to 90% of your way toward plate away and say, “You know
refined carbohydrates that are a healthy eating strategy. Now what what? This was great.
in your diet. And that would take does that leave? There’s more whenever I need it.”
the form of the flours that are in You can box this up and take it
breads, pasta, cereals, cookies, Well, that leaves meat, fish, fowl, home. You can throw it out. You
crackers, things like that, and chips. eggs, nuts, seeds, vegetables, a little can give it away, whatever. But just
Do what you can to eliminate bit of fruit, some starchy tubers, because it’s on your plate doesn’t
those refined carbohydrates. I can’t lots of herbs and spices, some mean you have to finish your plate.
remember the exact name of the healthy fats and oils like avocado So start to develop this skill to
study. But one of the most seminal oil, coconut oil, butter, ghee, lard in recognize when you’re truly hungry
studies done in this whole area some cases. It’s a pretty impressive and when your appetite has taken
was on it looked at what we call array of foods that you can mix and over your life.
acellular carbohydrates. These are match to create a very, very healthy
So I think that happens with so And that’s really, I think, something Mark Hyman has his idea of being a
many people is that it’s really a that we’ve begun to as a society pegan, which is like a Paleo vegan.
daily fight over portion control and we’re just overlooked it. We have so Another doctor friend of mine,
calories because their brain is just much tack in so many other things Dr. Robin Berzin, has talked about
so attuned to consuming calories. going on and so many distractions plant-based Paleo. Obviously the
And you get in a position where that we don’t stop and think, “All benefits of vegetables have been
you’re just, you finish lunch and you right, I’ve been sitting in my chair for seen. And I think more and more
start thinking, “What’s for dinner?” four hours, typing away. My back people are looking to see how can
And I say that’s no way to live your is numb. My quads are stretched. we get an emphasis back on that
life. Yes, enjoy every bite of food. Maybe it’s time to stand up and just rather than the emphasis on the
But don’t let food literally run your go for a walk.” meat all the time.
life and dictate what happens to
you from hour to hour. This ability to listen to the signals What do you think about that
of your body becomes yet again and what are some of your best
James: Absolutely. It’s almost like another very valuable skill that not practices in that regard?
a social structure, isn’t it? It’s like only manifests itself in how you
that’s what the mind is used to eat and whether or not you lose Mark: I agree with it, number one.
having. You have to have three weight because you’ve finally dialed I think that vegetables are still the
square meals a day. And so it just your eating in, but whether you get in terms of quantity ought to be the
became part of the social fabric of injured playing a sport because you largest part of your meal or your
society that people would eat in a haven’t paid attention to signals or plate. If you’re, say, either a noon
certain pattern. And I completely whether you get a cold or the flu meal or an evening meal for sure
agree with you. This comes from because you burned the candle at and maybe in some cases even a
someone who has been very maybe both ends and stayed up too late breakfast if you’re having an early
irresponsible and particularly not and didn’t get enough sleep. morning meal. Two-thirds of the
in that conversation at all as far as plate could be vegetables.
being able to have that sort of self- And I think we all know what the
control to stop. And I really feel like right answer is. But we are all The other flip side of that is the
you’re hitting on something there. distracted by God knows how many recognition recently that we don’t
other things going on in our lives really need as much protein as some
And in fact, what you hit on there that we’ve lost that innate ability to of the original Paleo minds, myself
really reminds me of what you were stop and kind of go, okay, what’s included, thought. Maybe there are
talking about before as sort of like really going on with me? people who can get by on fifty or
the elimination diets where what Tune out the noise and go inward a fifty-five or seventy grams of protein
it seems to be is really getting in little bit and say, okay, this is what a day. And even someone like myself
control and understanding your own I’m feeling. And this is where I am who’s still fairly active. Maybe I don’t
signals, whether it be hunger signals right now. And this is how I feel. require 120 grams of protein a day
or feeling how you feel about food And this is what I need to do for to not just function off of only but
because it almost seems like it’s that myself right now. to not get sick and maintain muscle
process of really getting to know mass and do all of that.
yourself that seems to be the most James: Absolutely, yeah. Just
important in the long-term. one more thing on the diet side I did a thought experiment a while
of things because I’d love to get back I want to share with you. And
Mark: Well, and not only does that into some of the other factors, it’s sort of interesting because
apply to the diet, but then it starts to too, with that can turn and turn people, I think in general, in this age
apply to your exercise. Is today an off these healthy and unhealthy of plenty like to go through life with
appropriate day to work out because genes. I see a sort of a feeling for this idea that, “Well, I’m going to
I’m tired or I’m sore? It applies to people who have been very Paleo see how much I’m going to eat and
your sleep. Even though I want to in their concepts, talking about not gain weight.” They don’t even
watch the next episode of Game eating meat. Obviously Paleo’s been necessarily consciously do this. But
of Thrones, it’s 11:00 P.M.. And I’m mischaracterized sometimes as the their brain is thinking, “What’s the
tired, should I go to bed? I mean as meat diet. most amount of food I can eat and
you start to become attuned to diet not gain weight? So I’ll push the
and appetite, you start to become I see a movement towards really plate away when I’m full. I sort of
attuned also to the other signal that getting in touch with the vegetable know my limits. I’m jogging thirty
your body is giving you. side of healthy eating as well. So miles a week. So I’ll burn that off.
But how much food can I get away concept that is antithetical to this had those genes been turned on in
with?” gluttonous age of plenty that we an acute response to a trauma or to
live in. some form of infection.
And you ask a lot of runners in
particular, but triathletes and James: Yeah, absolutely. Well, So I want to be careful that we don’t
cyclists, why do you run so much? it’s definitely an interesting start to think in terms of some of
And the answer will be, well, I conversation to have. And I’m sure our genes being unhealthy. Even
love to eat. Well, that’s sort of that as people start to move down the MTHFR gene or the BRCA1
interesting. Okay, so you’re cycling the journey of finding out what and 2 genes. They’re there for
because you love to eat. I’m not works for them, this would be a purpose. They will predispose
sure I get the connection. But I think probably a next logical question. some women, for instance, to
you draw the line and you assume And it’s great that obviously you’re a breast cancer. But they do have
that they’re cycling because they little bit further down the road than a function. And to label them
can burn off so many calories that most people in terms of knowing unhealthy is a bit of a misnomer.
they will deserve another big meal. yourself and doing this. You’ve been What we need to do is think more in
And a lot of people live their lives doing this for a long time. And so it terms of okay, how do I avoid those
this way. And even people who are seems like that’s a logical reversal manifesting themselves in certain
sedentary will say, well, I can eat X of the whole thinking process. So circumstances?
amount of meals a day and that’s those are some great ideas with
my set point and not gain weight. regard to food. Like if you have a predisposition
to lung cancer and you smoke
Well, I thought a while back, what And I know you have a ton of cigarettes, those are genes that are
if you took the reverse of this and resources. If you’re listening to this, turning on in response to cigarette
did a thought experiment and said, check out smoke that as far as they know
“What’s the least amount of food they’re reacting in the short-term
that I can eat and still maintain my Mark’s Daily Apple. Get the regular to an insult that over the long- term
muscle mass and my body weight email. It’s awesome for regular manifests itself in cancer.
and my energy and not get sick, content. And we love it here at the
and most important of all, not get Evolution of Medicine™. But there When you are predisposed to type
hungry? In other words, what’s the are definitely other things outside II diabetes, whether because you
least amount of food it takes me to of food. You talk about these have a slight, familial predisposition
sustain myself and not be hungry?” hidden genetic switches. Where are to it and you overdo the intake
And that’s a key element here. And the leverage points for people to be of sugar and you don’t exercise
maintain all of those other essential able to turn on the healthy genes enough, those aren’t bad genes.
aspects of my life. and turn off the unhealthy genes Those aren’t unhealthy genes.
with non-food factors? And I’m sure Those are your human genes
And I found that it was probably there’s some obvious ones. And I responding to the signals you’ve
30% fewer calories than I had been know that you have really found given them. And in this case, they’re
eating. It boggles my mind how few some non- obvious ones as well. So saying, “If this guy or this gal is
calories it takes me to get through what are some of your favorites in going to be taking in that much
a day and to sustain energy and that way? sugar and not exercising, then we
immunity, muscle mass, and once have to make these muscle cells
again still not be hungry. And I Mark: Well, first I want to back track resistant. We have to increase the
think if a lot of people did this same a little bit and talk about healthy amount of glucose that we store in
kind of thought experiment, and genes and unhealthy genes. The the fat cells because high levels of
literally for a while the experiment body doesn’t know that the recipe glucose are poisonous and we don’t
well, how little food can I eat and is healthy or unhealthy. It’s just want them floating around in the
take the edge off hunger, have my these genes do certain things. bloodstream. So we’re going to try
energy? They are predisposed to certain and store them in the fat cells.”
functions. And sometimes like if
I think that they’d start to come to a you talk about genes that cause All of this stuff is just your body
point where, once again, that those inflammation, you can’t really responding in a way that if it had a
extra ten pounds would fall away, label those as unhealthy genes. brain would be saying, “I think this
and the blood sugar would be even They’re just genes that are set up is healthy in the short-term. I think
better. And the lipid profile would to respond to certain stimulus that we need to do this to address the
improve. But it’s just an interesting might have been a life-saving event situation in the short-term in order
to maintain homeostasis, in order having had too much sun. expression.
to be healthy.” So it’s not necessarily
an issue of turning on unhealthy So why would that be? Well, sun is Mark: Well, just getting dirty. I
genes versus turning on healthy critical in, the UVB rays from sun, mean going outside and playing
genes. It’s just finding out what are critical in converting cholesterol in the dirt. Our GI tracts hold
those genes are and being able in the skin to vitamin D. Vitamin 100,000,000,000 bacteria that
to point them in one direction or D is a hormone-like vitamin (in our there for our benefit, for
another. Does that make sense? fact, it probably should have been the most part. There’s a balance
classified as a hormone rather than between good bacteria and the
James: Yea, thanks for clarifying a vitamin) critical to our immune unhealthy bacteria. But we have
that. And I would go a step further response. 100,000,000,000 residents within us
that thinking of anything within the that are not us.
body as, you know, anything innate So when we have low levels of
in the body as something as always vitamin D, our immune ability to And by the way, only 10,000,000,000
unhealthy is probably not a good fight infection decreases. It’s also to 15,000,000,000 that are us. So
plan any way. Honoring and respect involved in mood elevation. So low most of us, most of the cells in the
the amazingness that is your body levels of vitamin D are associated human body are not human cells
is probably a good starting point. with depression. And this can all but are bacteria.
be fixed so much more readily with
Mark: It’s an incredibly well- some sun exposure, five to fifteen But we need to feed those guys,
designed, efficient machine that minutes a day, two or three days a and we need to repopulate the gut
over millions of years has arrived week, of unprotected sun exposure with new strains. And historically
at this formula for developing and to create enough vitamin D. And for millions of years, that happened
building a strong, lean, fit, happy, that’s all, by the way, happening as as a result of just not bathing so
healthy, productive body. Where a result of genes being turned on much that we washed away all
we got in our own way is through or off. the bacteria off our hands and
processed foods, through inactivity, not rinsing or washing our food
through lack of sun exposure, So there are genes that cause so much or bleaching our food
through artificial light that allows us the transformation of cholesterol so much that it destroyed all the
to stay up late at night. into vitamin, and they do that bacteria that we would otherwise
through building proteins that be consuming and using to
And all these things kind of in some become enzymes that then make repopulate our gut.
regards add to the enjoyment of that conversion. So that’s just one
life. It’s kind of fun to stay up late example of the body’s perfect So one of the things we look is
and party and have television and setup for creating a very important just getting outside. Gardening,
go to clubs. It’s kind of fun to eat hormone in the body that we just for instance, in addition to being a
salty, crunchy, fatty food that’s not sort of, because we live indoors passive medicated experience, in
good for us. Even though it’s not or we work in buildings that have addition to being an opportunity
good for us, it’s kind of fun to eat windows that don’t let in the to grow your own herbs and spices
it at times. So really we have to burning rays, the UVB rays, thinking and vegetables also serves as a
dig down and understand how the we’re doing ourselves a favor when way to expose soil organisms to
body works and then find these in fact it’s almost quite the opposite. your skin. And presumably even
hidden genetic switches and direct pulling a carrot out of the ground
them through these behaviors James: That’s a huge, huge point. and then just brushing it off instead
including the foods we eat. That’s certainly something that of washing it off and taking a bite
I’ve come to see from all these of that, these are little things that
So that’s just as an overview. conferences. Obviously they’re the body, that its genetic recipe
the overview of what people are has come to expect from us, And
Now another example might be, told generally is slather on the yet we’ve denied it because we’ve
we don’t get enough sun exposure. sunscreen, stay out of the sun. And become so hygienic. And as a result
And even though the medical I don’t think it’s making us healthier of doing this, certain genes get
community has warned us to stay at all. What are some other areas, turned on.
out of the sun, I would argue that Mark? I know you’ve written on
more people get cancer as a result your blog of other areas in our There’s actually more genetic
of having aggressively avoided the lifestyle that have a significant and material in the bacteria that live in
sun than ever get skin cancer from sort of leveraged impact on genetic our gut than in our own genome
and in our own DNA. So there are a might be much more easy and cost- the cases with a dietary intervention
lot of genetic switches being turned effective to just start a new chronic combined with appropriate
on or off based on those sorts of disease management system from exercise. That’s just one example.
activities that place in the gut biome scratch. And so what I wanted to
that are then redirecting traffic do here at the summit was to bring Arthritis, bone density issues.
to make vitamin D12, take create people who not only have great Women in the United States are
serotonin that helps us feel better, ideas about how to create health, facing some bone density epidemic.
that help digest certain foods. but also who have managed to Well, it’s not because they have a
scale their impact with technology Fosamax deficiency. It’s that they
It’s crazy the amount of cool stuff sort of around a table and ask them don’t do enough weight-bearing
that happens in the gut that we about their thoughts. activity. And when you don’t do
take for granted and really take for this sort of weight-bearing activity,
granted when, for instance, we go So, Mark, we’ve got these people the bones have no reason to get
to our physician because we have together. We’re sitting around a stronger.
an upper respiratory tract infection table, and it comes around to your
and insist that they give turn to talk about what your unique If all you do is sit around all day,
contribution would be to starting the body goes, “Hey, I don’t need
us a Z-pack or some form of healthcare from scratch. What to build strong bones. That’s
antibiotic that’s not only going to would be your thought? ridiculous! Why do I need them?
work on the virus that we truly have I’m not using them.” Conversely, if
(because we don’t have a bacterial Mark: Well, I guess the first thing I’d you go to the gym and you do some
infection) but is also going to kill do is do whatever was possible to weight-bearing activity, the bones
off all the healthy bacteria in our educate not just citizens in general go, “Well, if she’s going to try this
gut and make us start over from but the medical community in again, we better get stronger.”
scratch. specific of the true nature of why
people get sick. If you set aside Now, what does that look like in
James: Absolutely, yeah. Well, for a minute all the trauma that the ordinary person’s life? Well, it
that’s exactly it and yea all the new happens—the auto accidents, the means that if you’ve worked on
citizen science projects like uBiome injuries, the swimming pool stuff, your muscle strength and your
and the American Gut Project are and all the traumatic stuff where balance then when you get up in
showing that getting your hands people show up in the emergency the middle of the night to go to the
dirty and maybe having a pet and room—you’d see that 90% of all bathroom and you trip over your
those kind of ways are significant hospital presents are a result of cat, now it’s a question of do you fall
increases in the microbiome, more lifestyle choices. They’re a result of and break a hip and then wind up
so than food and other things. So diet choices, exercise or not choices, in the hospital and get pneumonia
that’s a great point. smoking or not, and that if we could and then die because you couldn’t
understand the immense power clear your lungs because you hadn’t
So you said the words there, that just making other choices worked your lungs sufficiently?
starting from scratch, Mark, and would have over the alternative
throughout this summit what we’re choices over creating disease and All of this goes back to some
really talking about is my thought moving away from disease towards lifestyle choices that you could’ve
is that we have a medical system health. made. You could’ve done some
that was really designed for acute weight-bearing activity. You could’ve
disease. It was reactionary. It was Thirty million Americans and maintained a healthy body weight
designed to see a problem and then probably a half a billion around the and body mass. You could have
solve that problem. And potentially world have type II diabetes. Type supported your immune system
that system is being re-tooled for II diabetes is a stupid disease. I’m and not gotten pneumonia in the
chronic disease. But potentially that sorry to anybody out there who first place, all of which happens as a
system is not really designed for has it. But you don’t need to get result of turning on certain genetic
chronic disease. it. It is the body’s manifestation of switches, all of which is under our
a lifetime of not paying attention control because we can choose the
And so the cost of re-educating to your glucose load and not foods we eat. We can choose the
all the doctors, all the systems, all exercising appropriately to make types of exercise we do. We can
the hospitals, to try and get them sure that the muscle cells remain choose the amount of sleep we get.
to do things differently for chronic insulin sensitive. And yet this could We can choose the amount of sun
disease is so great that potentially it be prevented in probably 95% of exposure that we get.
So when you look at all of the things years if everybody embraced this and you’re either in range or out
that can go wrong in medicine, the way of living right now. of range. And then your personal
autoimmune diseases of which I physician says, “Well, we need to do
think there are seventy-five or so James: Absolutely. Well, it’s something about this one number
known autoimmune diseases, they interesting that you mention here because it’s out of range,”
probably have a dietary etiology. education because the root of or whatever. So much of this has
If you look at heart disease and doctor is teacher. But in a certain become mechanized and digitized
the millions of people in the way, why do we need doctors that I would submit that you could
United States, and again tens of to provide this education when take a smart kid out of college and
millions/hundreds of millions people like yourself have been they could become a physician in
around the world, there are dietary able to really cross that line. And two years if they were willing to
interventions that are far more instead of doing this on a one-to- train for a specialty right off the bat.
effective than statin drugs. one basis, that is really desperately
inefficient, you’ve been able to Almost more importantly, I think
The statin drugs just give you a reach thousands and hundreds of that there ought to be a level of
little bit of leeway to go about and thousands even maybe millions of physician that was just below an
continue. And this is the problem people with your message through MD but that (and PAs are taking this
with most drugs, by the way, is that the technology that’s now available. on right now) where there’s time
they’re a short- term alleviation, Could you see that potentially that spent educating the patients. So
a short-term bandage solution we don’t necessarily doctors to be you take the blood work and you
to a problem that needs to be educators if we could work on the take the scans. And you say, “Okay,
addressed at the base level. What is sophistication and proliferation of according to what I see here, here’s
causing this issue? What is causing some of the technology systems how you need to eat. Here’s the diet
this buildup of plague? What is that you’ve been a big part in that I’m going to prescribe for you,
causing this increase in sugar bringing out this message? and here’s the exercise regimen
accumulation in the bloodstream? that I’m going to prescribe to you
What is causing the deterioration Mark: Well, I’ve had a modest that will fix or that will reduce
of chondrocytes in the joints? What proposal that I’ve been circulating the risk factors that are currently
is causing the amyloid plague in for about ten years that suggests presenting themselves,” or that will
the brain? And it all comes back to that medicine today, there’s no fix the current problem which is
lifestyle choices. resemblance to what it ten years lightheadedness, depression, joint
ago let alone forty or fifty years ago. pain, stomach pain, whatever it is.
So if you can enter life, like in And you go to an orthopedist and
the school systems I’d say if we you say, “I got a bad knee,” and the We know that there’s a far more
started teaching a Paleo approach. orthopedist will say, “Well, I don’t do efficient and effective solution
Like in the old health class, you knees. I only do elbows.” That’s how through a lifestyle change—a diet
know, health education which was specialized medicine has become. and an exercise change, if you will—
typically taught by the phys ed than through prescribing a pill that
teacher who had to have one other And when you realize that when all it does is mask pain.
class to teach because no one else you find a knee person, when you
wanted to teach health. If you could go to have the knee operation, that James: Yeah, absolutely, Mark.
get this into kids’ heads early on, it’s physician knows most of what he That’s a key point. And I think
so much of what’s available to them knows from a twenty-eight year old certainly here on our point there
is a result of the choices they make. sales rep from a medical supply which is really that doctors
company who scrubs up with giving this education in whatever
If you can get the doctors to him and guides him through the model would be a very expensive
understand that if you spent more operation. You realize that medicine education for anyone. And I
time educating your patients on has become much more a) certainly see that.
ways to eat and less time just specialized and b) most diagnoses
writing the obligatory script for are done with algorithms that use You mentioned Pas. But we’re
the Nexium or for the Glucophage blood tests, urine tests, scat cans, seeing at the Functional Forum
or for the statin drug or for the MRIs. what we’ve been encouraging is
antipsychotic drug that has nothing this connection between doctors,
to do with an organic brain issue, It’s not like it takes a one extremely coaches, and technology to really
we could knock a trillion dollars off sage individual to read your blood be able to do that because there’s
the annual health budget in two work right now. You come up, a whole new level of coach coming
out. We’ve got health coaches. and some of the more developed and even military to embrace this
There’s nurse coaches. There’s countries with one individual because their physical performance
other people who what their goal taking on learning this what it takes is so critical to the safety and
is really to help to implement the to understand what’s going on protection of the cities that they’re
recommendations of the doctor, because it’s a tough way of living associated with. When we can get
who understands functional to enter blindly and go just on a couple of those large-scale, I’ll
medicine, understands food faith. “Well, I’ll just eat this way. I call them studies although they’re
as medicine And that’s a really don’t need to understand why it’s actually not studies anymore. It’s
powerful combination. happening.” been proven that they work. And
you start to see the results.
And then if you can synergize that What we’ve done and what I’ve
with technology that allows that to done is spent most of my career You start to see that the cities are
scale and also to provide support trying to educate people as to saving millions of dollars, tens of
in between visits, now I think we what’s going on at the level of millions of dollars on insurance
have some real structure to be able the cells, at the level of the gene premiums and on lost wages or
to help people to make behavior expression so that you really, truly disability and things like that. It’s a
changes, maintain those behavior understand why you’re taking on market-driven phenomenon when
changes which is, if you take out this otherwise bizarre behavior, it’s successful. At some point, it has
trauma, like you said, that’s the why you’re going outside and to leave the grass roots and become
crux of evolving medicine to a getting some unprotected sun in defensive and quantifiable in terms
point where it’s really successful the face all of the admonitions, of money saved. And when that
at chronic disease management. I why you’re increasing your intake happens—and it will happen fairly
really love some of your thoughts of saturated fat and decreasing soon—then I think corporations will
there. your intake of whole grains in the come on board and go, “Well, this
face of government advocating the is clearly what we have to do not
So, Mark, what do you see in the contrary. only to save money, but to offer a
next few years here? We started benefit to our employees.”
this conversation. Where do you I just want you to understand that
see the conversation going now? this stuff is really cool science. And James: Yeah, absolutely. If you’ve
You say in the last few years maybe if you can understand and then been following our content this
more focus on plants, maybe more if you can embrace it and if you year, if you’re listening to this,
focus on including certain things, can take it on yourself and get the definitely we’ve been focusing on
continuing increasing focus on results, then other people will see exactly that. We had a podcast
individualization and just seeing what you’re doing. And this has earlier in the year from a business
what works for you. Where do been happening. This is the way the owner in Lubbock, Texas who
you, if you were to look into your movement’s growing. It’s basically a started with chiropractic then
ancestral crystal ball, where do you grass roots movement. nutrition and exercise and
see things moving in the next little eventually put a functional medicine
while here? “Hey, how did you lose fifty pounds? clinic in his factory and prescription
And you look great. What’s going drug usage went down 62% in the
Mark: I think everything’s trending on? You’re off the meds and your first year. The numbers just start
toward a larger population of skin cleared up. How’d you do looking really good.
healthy people. The problem is that that?” It’s one person telling another
it’s still a small subset of the overall person how they did it and then And I think companies like Safeway
world population. In the United saying, “Here’s a book on exactly and Parker Hannifin are taking this
States, we become myopic when we what’s going on. And here’s a up to prove this out as a money-
consider our own issues and then couple of cookbooks on how to eat saving model. And I’ve said since
however many 1.2 billion people in this way.” And you’ll find that not we’ve started this journey that it’s
India and so on, many of whom are only are these meals great, they’re going to be when that kicks in and
starving and living a subsistence healthy for you too. That’s the grass businesses start demanding this
lifestyle. So we can talk about roots movement. en masse, that’s when we’re really
worldwide problems. going to see an acceleration in this
But then at the next level up, evolution of medicine.
But the solution sort of has to if Robb Wolf is working on City
start at home and has to start with Zero, his project here to get Mark, I really, really value
us in the United States anyway municipalities with police, fire, everything that you’ve shared today.
And I know that the people that are about, Mark, would just be really
listening will, as well. I really want to significant. So this has been The
share my appreciation from myself Evolution of Medicine™ Summit.
and all the team for the work that I’m your host James Maskell. We’ve
you’ve done to be able to bring this been with Mark Sisson. And we’ll
to the masses thus far. And we look see you next time.
forward to working more together
to engage doctors and other health
professionals into some of these
topics.

It’s a big part of the evolution


of medicine to look at these
evolutionary type of concepts,
particularly with nutrition. And I
really feel like it’s a strong team
that’s coming together to make it.
And I feel like you’ve done so much
to add so far. And I know you’re just
getting started too with some of
your bigger goals there. So thank
you.

Mark: My pleasure, James. Thanks


for having me.

James: So this has been a great


start to the ancestral, Paleo
day here at The Evolution of
Medicine™ Summit. If you want
to find out more about Mark
Sisson and his work, you can go
to MarksDailyApple.com. Sign up
there.

Mark, where’s the best place to go


for physicians who are interested in
learning more about your work?

Mark: Well, MarksDailyApple.com.


PrimalBlueprint.com we have a
certification. We have an expert
certification program there that
a lot of physicians have taken
already and are just raving about
the education that they’ve gotten
there and how they’ve been able
to deploy it in their practices.
So Primal Blueprint Expert
Certification.

James: Great. Go and check those


two things out. I think that most
patients and physicians if we could
get the word out to that, the ripple
effects that you were speaking
Genetic Defects and MTHFR
Wendy Myers, FDN-P with Sterling Hill
Click here to watch this interview!
The purpose of this presentation is to convey information.
It is not intended to diagnose, treat, or cure your condition or to be a substitute
for advice from your physician or other healthcare professional.

everyone on the planet, often being Wendy: So let’s talk about MTHFR.
the proverbial stone that was left What is it and why is it important?
unturned in chronic illness of any
type. As a result, Sterling launched Sterling: Well, MTHFR provides
MTHFRsupport.com to learn and instructions for making
Wendy: Hello, everyone, and thank share the knowledge of genetic methylenetetrahydrofolate
you for joining us. My name is polymorphisms or SNPs and their reductase. Its catalytic
Wendy Myers and you can learn affect on health. activity for MTHFR is 5-
more about me at Liveto110.com. I methylenetetrahydrofolate, which
brought together all the top experts Her passion is to help educate is the active form of folate. This
in natural health for the Medicinal the world of the true root cause should not be mistaken with folic
Supplements Summit to help of chronic disease and link expert acid. And also, NAD is also part of
you learn about making the right healthcare providers with those the catalytic activity. It stands for
supplement choices, choices that in need. Since then, Sterling has nicotinamide adenine dinucleotide
can vastly improve your quality of created genetic apps for the phosphate.
life and prevent disease. alternative medicine community.
She helps people get to the root The cofactor for MTHFR is
Today, we are exploring the MTHFR cause when it comes to diet and FAD, that’s your flavin adenine
genetic SNP, which about 50% of environmental factors that impact dinucleotide, which consists of
the population have, and what DNA and teaches practitioners and riboflavin found in vitamin B2. And
supplements you may need by scientists around the world how its enzyme regulation for the MTHFR
looking at your genetics. Today, to pinpoint pathways that maybe gene is S-Adenosylmethionine,
our guest is Sterling Hill Erdei, the compromised in their most difficult better known as SAMe, which is a
founder of MTHFRsupport.com. patients. Sterling teaches them common co-substrate involved in
how to manipulate compromised methyl group transfers.
She was a highly successful genetics with nutrition and
businesswoman for many years supplementation. When someone does have a defect
until 11 years ago when she of one of these genetic MTHFR
became ill with clotting issues. She MTHFR Support has come a long SNPs, he or she can have an array of
went from physician to physician way and Sterling is now researching problem related to folate deficiency
but her condition progressively with MIT’s Stephanie Seneff, such as neural tube defects, spina
deteriorated. She lost everything. realizing that one of the reasons bifida, elevated homocysteine, poor
And as traditional medical thinking that many people are chronically ill methylation issues, miscarriage,
was failing, she reached out to the is because of glyphosate, Roundup cancers, and autoimmune diseases.
alternative medicine community Ready pesticide. Her knowledge
and the world of epigenetics. of this area has grown immensely Wendy: So what percent of the
and she’s now become one of the population carries MTHFR defects?
She learned that the basis of leading researchers and advocates
her clotting issue resided in the speaking out about the dangers of Sterling: Well, actually, the only
sulfation and methylation cycle. glyphosate and how it impacts DNA. ones that they really do study
After regaining her life, Sterling and bring out there are C677T
realized that the medical and lay Sterling, thank you so much for and A1298C. But believe it or not,
community knew very little of joining us on this summit. 98% of the population does have
epigenetics and nutrigenomics. She another defect with peer-reviewed
realized that these subjects were Sterling: Oh, you’re welcome. research attached that is impacted
of vast importance to the health of in some way.
Wendy: Okay. And so, what exactly it off. Six weeks later, you get back is possible deficiency by looking at
does this impact? When someone your results and then you can run their DNA.
has MTHFR, one of the MTHFR it through your app and it’s called
defects, what kind of supplements Sterling’s App, correct? Wendy: And so what can one do if
does someone need? they find out they have this MTHFR
Sterling: Yes, it is. And I never ever mutation?
Sterling: Well, it depends on which turn anyone away. I believe a true
way it goes. For instance, the C677T healer doesn’t turn people away, Sterling: Well, the most important
is going to be more the elevated so we get a lot of people that can’t thing is, if they’re chronically ill, to
homocysteine issue. Now, the even afford the $30 to run my kind of look at the entire pathway,
A1298C is probably going to be app. And they contact me through methylation pathway, but also look
more on the need for methionine. customer’s support. I never turn at other pathways such sulfation
So when you have a C677T and anyone away. first. That’s really important
it is impacted, sometimes you’ll because without sulfation working,
see more of an elevation of Wendy: Wow, that’s amazing. Yeah, methylation cannot work.
homocysteine and the need for and so you run it through your
methylfolate to bring it down. app and then you get a printout. Wendy: And so explain a little bit
It’s about a 50-page printout that about what sulfation is and the
And then on the other end, basically gives you the raw data that consequences if you’re not sulfating
sometimes with the A1298C, the you need about your genetic SNPs properly.
BH4 deficiency, tetrahydrobiopterin that’s not provided by 23andme.
deficiency, comes with that as well com. Sterling: Okay. Poor sulfation
as homocysteine and sometimes basically is hyperoxaluria. Oxalates
the need for methionine. And then Sterling: Yeah. Well, right now, it are nasty little buggers. They come
also, B2, being the cofactor for it, is is about 60 pages, because we’ve from GMOs, genetically modified
very important as well. added in new pathways like the foods. Glyphosate actually converts
cannabinoid pathway and now into glyoxylate. It does a lot more.
People always just think folate the iron metabolism pathway and It’s quite dangerous and there’s no
because that’s what they’re taught. thiamine pathway. And we have safe levels of it. And with oxalates,
There are so many other things that coming, I believe, also the glyoxylate what they do is they share the same
come into play with this gene. pathway because of glyphosate transport system as sulfation, and
GMOs. they start hogging up this transport
Wendy: So what can one do to system. And when they do, you
find out if they have an MTHFR Wendy: Great. Fantastic. can no longer sulfate your D3, you
mutation? shut down phase 2 liver detox
Sterling: Yeah. methionine synthase.
Sterling: They can ask their doctor
to run a test to check for MTHFR Wendy: Yes. And so when someone So, sometimes giving folate
defects, which I do not care for, gets his report, obviously, it’s quite supplements, you’d have to give
because you really need to look complex. Do you have practitioners them in massively high doses
at the larger picture, the whole on your site that help people to because even the smallest dose
methylation pathway. So it’s really interpret it and what it means for on certain people with other
good to go out there and do them and what kind of supplements mutations, you can actually backfire
something like 23andMe or DNA they need based on the report? and make them sicker because you
Ancestry. Then you can run through
a map, like the one I have created Sterling: Yes, I do. It’s always best haven’t opened that sulfation
in MTHFR Support, and we pull out not to treat the SNP, but treat the pathway up. And it’s crucial because
raw data that’s on the back end of person. So when, for instance, if it’s also, again, the sulfation of
23andMe and DNA Ancestry. And we see multiple HFE hereditary D3 plays a role in it when these
we generate reports and show hemochromatosis SNPs along with oxalates get too high.
different pathways. G6PD, SOD2, all we have to do, for
example, with our metabolism, we Healing the gut is really important
Wendy: Yes. So when you go in say, “Hey, big red flag,” check for because you cannot–all leaky gut is
23andme.com, you just do a simple ferritin and so forth. But we kind of hyperoxaluria. You cannot heal the
saliva test. I’ve done it. It’s very point them in the direction where gut if you have poor sulfation. You’d
inexpensive, it’s like $100. And send they should be testing where there have to get this open. And once
you open it, you’ll start sulfating carcinogen to people with DHFR Wendy: Yeah. And what is the
your D3, then you’ll make GcMAF, defects, which is another gene problem with a lot of these
and then that GcMAF has attacks that my app, MTHFR Support App processed foods that are enriched
on cancer or viruses, disease, of 23andME and DNA Ancestry’s with folic acid? What is that doing to
pathogens. It’s amazing. But raw data. And the dihydrofolate the population and people eating a
sulfation, basically, is one of the first receptor is directly linked to standard American diet that’s all of
pathways you look at before you colorectal cancer, because when it, all the grains, are all fortified with
even go in to get folate for MTHFR. impaired folic acid has a hard folic acid?
time converting into folate, which
Wendy: Yeah. Because I think a you get from certain foods like Sterling: I think, initially, what they
lot of people mistake that they— pastured eggs, leafy greens, beans, saw was it was an easy way to
whenever they get diagnosed and berries. And it becomes a effectively get folate into people.
by their physician or they do the carcinogen. But what they didn’t realize is
23andMe, and they see they one of that most of the population has
the mutation SNPs or maybe more. Also, folic acid has been found to trouble converting. For example,
And then automatically think, “Okay, prevent folate from crossing the we didn’t keep an eye on it here in
I have an increased need for folate blood -brain barrier. The FOLR gene America, but when Mexico started
or methylfolate and to take that.” is critical here, and many people synthetically fortifying their food
But many people, it can give them have it impaired. with folic acid, colorectal cancer
anxiety or negative issues, because tripled.
, like you said, their sulfation FOLR actually stands for folate
pathways are blocked. receptors, which are found in your Wendy: Oh.
brain. Many children with autism
Sterling: Yeah. And then also have cerebral folate deficiency, so Sterling: Yeah. So it’s very, very
COMT. You never ever give we know they have this defect. hard for many people to convert.
somebody with COMT V158M Within a year, colorectal cancer had
and H62H homozygous and then So, as for women trying to conceive, tripled in Mexico from folic acid
also having VDR Taq homozygous folate is very important. And if fortification. And sadly once you
vitamin D receptor, you never ever you are having trouble converting get something through the FDA
give them high doses of methyl the folic acid into the active form put in food as a supplementation,
donors, that’s like giving somebody of folate, your red blood cells can and it’s very cheap, the folic versus
methamphetamines. become misshapen. And your the folate. But once you get that
uterus is made up of capillaries, put in, you know it takes many
Wendy: Yeah. so to feed the uterus, your folate years, decades sometimes, to get it
levels must be optimal in order to removed.
Sterling: You can actually kill have healthy red blood cells that
somebody. are shaped right to get into the Wendy: Yeah. And probably very
capillaries to feed the uterus. difficult to prove that a vitamin is
Wendy: Yeah. And so it just causing cancer.
begs the importance of finding a And folate also plays a huge role in
qualified healthcare practitioner the development of your fetus. This Sterling: Yeah.
before you start supplementing just is why neural tube defects like spina
amateurly based on your genetic bifida are directly linked to folate Wendy: Next to impossible. So,
SNPs or printout of your MTHFR deficiency. So when your fetus when there’s a chronically ill patient,
Support Sterling’s App printout is developing, in every trimester, why is it so important to look at
from 23andMe. It could be very, it’s crucial to have accurate levels their DNA?
very complex. of folate to prevent the neural
tube defects. It is also important Sterling: Well, because other
So why should women, trying to to make sure you’re taking factors come into play here.
conceive, take folate and not folic your prenatal that contains L-5- For instance, let’s say, you have
acid? methyltetrahydrofolate. somebody chronically ill and
they come in and they say, “Hey,
Sterling: Okay. Folic acid is very And it is also crucial that you are I have this MTHFR defect,” they
hard for many people to convert consuming a diet rich in folate, not don’t realize other things can be
into the active bioavailable to be mistaken again with folic acid. hindering it. For instance, MTHFR
form folate. It can actually be a is impacted by G6PD deficiency,
which is the most common enzyme We look into all the genetic eating the food. It’s catastrophic.
deficiency in the world. G6PD is components on many v ariant
part of the pentose phosphate reports at MTHFR Support. Sterling: It’s awful. Brazil is really
pathway, and it is responsible for bad. And Zika virus has been
the production of NADPH, which Wendy: Yeah. You’re doing a lot around for 45 years. They’re trying
is required for the MTHFR gene to of work in this area and raising to blame all the brain inflammation
function properly. And over 400 red flags about the danger of the on the children being born to
million people worldwide have had glyphosate. Can you talk a little bit Zika virus and we kind of think
G6PD deficiency, and many do not about that and the fact that you’re it’s their overuse of glyphosate.
even know that they have it. So this going to Capitol Hill to discuss They have corn and soy there in
is approximately, I’d say, one-in- this very grave issue that, clearly, Brazil, including their larvicide and
sixteen people in the world do have is negatively impacting people’s then they just upped their vaccine
this deficiency and it’s sad how it’s health? schedule.
never tested.
Sterling: Yeah. It’s scary and many And for them to say that, all of a
Now, when somebody is G6PD of the facets, how it impacts DNA. sudden, after 45 years, for instance,
deficient, they’ll shut down phase 1 For one, glyphosate, the actual the Zika virus is now causing
liver detox because the red blood name for it is N-phosphonomethyl problems 45 years later and it’s
cells literally start exploding and glycine, okay? And you hear that been around for 45 years, that’s
your cytochrome P450 genes, word methyl in it. So people with false. I truly believe it’s all the
which make up phase 1 liver detox, this COMT down regulation, the glyphosate and the larvicide from
are heme dependent as well as COMT mutation is impaired, COMT, Monsanto and, also, the moving,
NADPH electron transport pathway they can’t handle an overload of adding in more to the vaccine
dependent. methyl donors, so we know it’s schedule on these children in Brazil.
bad there. And also you hear the
And GMOs actually have been word N-phosphonomethyl glycine. Wendy: Yeah. I absolutely 100%
found to reduce the G6PD enzyme, Glyphosate is replacing the amino agree with you. It’s just a corporate
avoiding beans and taking food acid, glycine, in the body, that’s cover-up. So let’s talk about when
source Cs instead of ascorbic acid pretty scary in itself. someone has–like why can’t
is better, much better way to go someone just look at a genetic SNP,
when somebody does have G6PD Then also, glyphosate, when it single nucleotide polymorphism,
deficiency. Also vitamin K, at this attacks the shikimate pathway, it such as, say, MTFHR, C677T, and
time, can also harm the individual destroys your microbial, your gut then supplement with folate?
when deficient of the G6PD enzyme. microbiome gets destroyed and
your oxalates take over, because Sterling: Well, again, many factors
Then there’s Vitamin B1, it’s needed the microbial that it does destroy come into play here. For instance,
for the production of NADPH, which actually do break down oxalate. if someone has a non-secretor
is also required for the MTHFR gene FUT2 status–I don’t know if you’ve
to function properly, and can hinder And when this happens, you can no ever heard of the blood type diet,
your phase 1 live detox. Then longer sulfate your D3. When you they’re the secretors and the non-
there’s sulfation, many people have can no longer sulfate your D3, you secretors. On my variant report,
sulfation impaired. I truly believe can no longer make GcMAF, which we look at three critical FUT2 SNPs,
that the biggest thing out there has 20 attacks on disease and six and when all three of these are
impairing sulfation is Roundup attacks on cancer alone, including homozygous—and that’s 20% of
Ready GMO seeds and Roundup the cannabinoid pathway. the population, they cannot make
weed killer, because glyphosate H antigen and are chronically low in
converts into glyoxylates, and Wendy: Yeah. And it’s amazing beta-glucan and galactosaccharides,
oxalates do share the same what’s happening, and we see in which are what we know to be class
transport system with sulfation. other countries where they’re just of prebiotics that are needed for
And when oxalates start hogging using a ton of glyphosate. They’re essential probiotics to stick in the
up this transport system, you have using a ton in the U.S. but there’s gut. Without these beta-glucans
impaired sulfation and you’ll see other countries where there’s–I’ve and galactosaccharides, you’ll
sulfate waste in your own urine. read reports of the farmers that always be fighting an uphill battle
This is what we call hyperoxaluria, are using this just becomes so ill so with someone trying heal their
which will also cause poor function quickly because they’re exposed to leaky gut in order to assimilate their
of the MTHFR gene. it so much more than, say, someone food and absorb supplements like
folate, which is needed for MTHFR. And when you see high glutamate Levaquin, I started having pains
and low GABA, which then will shut down both my arms and legs,
Then there are two other genes, down phase 2 liver detox, where screaming, and then I went blind
DAO and ABP1. They are part of MTHFR resides. in my left eye temporarily because
this glyoxylate metabolic process I had a TIA from it. So, apparently,
and help breakdown dopamine and And then on another note, taking I clot seriously when I have
histamine in the gut. DAO is also fluoroquinolone such as Cipro fluoroquinolones.
easily replaceable. When deficient and Levaquin along with NSAIDs
of the DAO enzyme, you prevent or steroid can permanently burn Wendy: Wow. So you said you had
sulfation of vitamin D3. You will see out these GABA A receptors, a problem with clotting. Can you
these people, who have optimal D3 we call these people, injured by tell us exactly what that is and how
levels, with high levels of D-1-25, fluoroquinolones, “Floxies.” I’m one you can tell if you’re susceptible to
which is also known as parathyroid of them. clotting based on your genetics?
disease. And when D3 is not
sulfating and it is staying in D-1-25, Wendy: Yes. So, based on your Sterling: Well, also, besides
it cannot breakdown into GcMAF, genetics, you can find out what genetics, it’s really good to look
which does have 20 attacks on kind of medications that you should at things like C- reactive protein,
disease, viruses, stealth pathogens, absolutely be avoiding. fibrinogen, platelet counts. But
and six attacks on cancer including when I was lying in the hospital with
the cannabinoid pathway. And Sterling: Yes. my first major clot, where I was
this must be addressed MTHFR to there, critical, for two and a half
function. This is what we call poor Wendy: Yeah. And so, you months, pulmonary embolisms,
sulfation or hyperoxaluria and it said there are fluoroquinolone internal bleeding, septic shock,
should stay on the methionine antibiotics? everything because the clot has
synthase, which is where MTHFR laid there for so long, I got a gram-
resides. Sterling: Yeah: Cipro, Levaquin, negative infection.
Tequin, Avelox, ofloxacin.
Then there’s another one. It And as I was lying in the hospital,
is the GAD gene. This gene is Wendy: Yeah. And that you told me a geneticist had started doing,
responsible for breaking down the at one time that you nearly died and also a hematologist, had
cytotoxin glutamate into calming from taking these, because you started doing a series of testing
neurotransmitter GABA. And its have that “Floxie” pattern on your on me, where that’s when I found
cofactor is P5P, which is the active genetic SNPs, and that you became out I had MTHFR. And they saw
form of B6. And P5P requires lysine extremely ill after being given a my homocysteine was high and
to help the receptors to be utilized dose of fluoroquinolone antibiotic. that was probably causing my
in the body. Now, when the body clotting because my red blood
is running low on B6, the body will Sterling: Yeah, on two different cells were misshapen. Then also,
make endogenous oxalate and occasions and I really didn’t see it I had hyperplatelet function. So
hinder sulfation, which then in turn until I went back on my medical they discovered I had factor VIII
shuts down methionine synthase, records. I had to have a series with hyperplatelet function and
that are known as phase 2 liver of surgeries because I broke my also factor XII with hyperplatelet
detox, where MTHFR resides. neck, and it was misdiagnosed as function.
whiplash years ago, over 21 years
So if you see high glutamate and ago. And I’ve had to have a series And what I realized later on,
low GABA on a neurotransmitter of surgeries since that serious studying all this, while going to all
test, you know that there is mechanical issues. these hematologists and specialists
something going on with the that had me on all of these things
patient’s sulfation pathway, such And on two occasions, I had life- like Coumadin and Lovenox, I had
as a diet full of GMOs, MSG, or B6 threatening pulmonary embolisms. to argue a point with one of the
deficiency, P5P deficiency, and/or And when we went back, they were hematologist because she told me
lysine deficiency. And we have the giving me IV Levaquin. And then I I would always be on Lovenox and
GAD gene on our genetic variant had another occasion where I had also Coumadin for life. And I said,
report in MTHFRsuport.com, the a UTI and my now ex-fiancée, who “That’s not true.” If that was true,
body’s, most likely, when you see is a cardiovascular surgeon, had I would’ve been on it when I was
this, making endogenous oxalate, given me Levaquin for the UTI. born. Something triggered this.
which is a fancy word for leaky gut. Within 10 minutes of taking the
And going back and looking at going on. This is the problem: it’s and you have discovered you have
sulfation, fatty acids, also getting always more than one thing going MTHFR, if you—take caution when
inflammatory foods and GMOs out on with chronically ill people. I try to using methylfolate.
of my life, I had been, now three tell people, “You’re not going to get
years, just on things like krill oil to well overnight, because you didn’t So, what are some of the other
keep my blood flowing well, and I’m get sick overnight. This took years.” genes and genetic pathways that
doing great. And it may take years to uncover people should look into when
it. I’m still uncovering stuff in my they’re chronically ill and trying to
Wendy: Wow, that simple. I love it. health. So I learn something new supplement?
every day.
Sterling: Mm-hmm. Sterling: Well, again, the COMT
Wendy: Yes. And I’m the say way, I gene, which stands for Catechol-O-
Wendy: Yes. And so, going back to learn something new every single methyltransferase, and people
talking about folate, I know that a day. I love it. So you think that who are homozygous for the
lot of people are probably thinking, anyone who has MTHFR or who’s COMT V158M mutation or H62H
“What type of folate should I chronically ill, that it’s perfectly okay mutation with the VDR Taq,
be taking?” What is the kind of for them to take like the synthetic which is the vitamin D receptor
problems or differences between, B vitamins that are methylated, SNP, who are homozygous, they
say, a food-based vitamin B and a that had been converted into this have trouble breaking down
synthetic vitamin B, because the methylated form. carcinogenic estrogens, methyls,
methylfolate is synthetic, correct? amines, dopamine, epinephrine,
Sterling: No. I, for one, don’t, and norepinephrine. So these
Sterling: Yes, it is. But the folate because of my COMT V158M and individuals should never be given
in our food does not convert, and H62H. I’m homozygous. And if I high doses of methylfolate and
it’s not the converted form. What was to take the synthetic converted never, really, should be given
scientists have done is converted it form of L-5- methylfolate, I would methyl B12.
to the next step for people that are take it extremely low dose. But I’ve
having problems getting folate from managed to heal my gut. And in the I’ve had many a phone call, like I
food sources to convert. I think that beginning, when I found out the said, form suicidal people who are
once you truly get these pathways true methylation pathway and stuff, in full- blown panic attacks because
established, to see where you’re I was taking about 200 micrograms their practitioners gave them
deficient, start eating right, staying a day, but I don’t even need that high doses of methylfolate along
away from things that inflame you anymore. And it’s really hard on the with high doses of methyl B12,
and getting your gut healed, you people who have this homozygous these mutations. And I compare
can get, for the most part, folate on COMT mutations and they’re down it giving the methyl B12 to this
your own. regulating their catecholamines. population with giving someone
Because you go in and give them methamphetamines. These people
There are those exceptions where, very high doses of methylfolate, do better on hydroxy B12 and/or
yes, methylfolate is going to help you can make them insane. You can adenosyl B12 when looking at their
them. actually cause heart attacks. I’ve had other SNPs and labs.
people call me like I’m the suicide
Wendy: Yeah. So do you think hotline at 03:00 in the morning, I’ve And then some other important
that – a lot of people are going to had to stay on the phone with them genes, two other ones, genetic
say, they’re listening right now, and for hours until I got them help that SNPs, are APOE2 and APOE4. We
they’re taking a food-based vitamin they needed from over-methylation call these people grain brain. Grains
B that’s produced from yeast. So with this COMT mutation. are not the best things for these
you think, for a lot of people, their individuals. And two things that we
body is not able to convert it to a Wendy: Yeah. see in common with the people
form that’s usable? who have these APOE mutations
Sterling: So, yeah, it can be kind of are elevated homocysteine and
Sterling: Some aren’t, especially dangerous for some people with elevated A1c, which are both
the chronically ill that keep on certain mutations to take high-dose hindered by poor sulfation and
taking one step forward and two methylfolate. hyperoxaluria. And GcMAF actually
steps back. They might need a little regulates A1c. So it’s important
support until somebody comes Wendy: Yeah. So it just goes to for these people to have optimally
in and figures out what is exactly show, if you are listening at home functioning sulfation pathway
along with adequate levels of D3 see that mutation. familiar with genetic SNPs?
to be sulfated into GcMAF to keep
Alzheimer’s at bay. There’s another one to do Sterling: Okay. Well, we call a
with clotting and it’s called F2 minus and a minus–we call that
GMOs are not meant for anyone prothrombin 20210A. Again, like good. That’s a good SNP. And
and really crucial for people to factor V Leiden, it is extremely rare then we call a plus/minus, kind of
stay away from that have APOE2 to find someone homozygous. you’re halfway cut off and we call
or APOE4, since glyphosate does it heterozygous. And a plus/plus,
convert into glyoxylate. Also, they Heterozygous people are at a higher we call homozygous, that you’re
really need to keep an eye on their risk of developing the clotting all the way cut off. I like to look at
fatty acids too, their 20s and 6s sometime in their lives when it like this, pretend you’re running
become very out of range from not monitored. And the F2 gene water down a sink and water is just
one another. And you know you provides instructions for making flowing fine, those people are great
need to have those balanced, a protein called prothrombin, also and they’re flowing well.
they need to be aligned with one called coagulation factor II. This
another to prevent inflammation. gene is also related to miscarriage Pretend you’re running water down
And then also, again, with the APOE as the uterus is fed with capillaries. a sink and somebody has thrown
mutations when you see tumor bacon grease down there and it’s
necrosis factor, TNF, mutations, Thrombin is also thought to be kind of draining a little bit slower, I
only once you get sulfation open involved in cell birth, division, call that heterozygous. Now, when
turmeric should be in their diet for proliferation, tissue repair, and the the water backs up and overflows,
life. But only when sulfation is open. formation of new blood vessels, I call it homozygous. And your
angiogenesis. And 2% to 5% of parents, you get a SNP from mom,
Then there’s factor V Leiden, FVL. Caucasian and 0.3% of African- you get a SNP from dad, you’re
That is another important genetic Americans are heterozygous for either going to grab the plus or the
mutation to look at. When factor V G20210A. It’s very serious and minus. And that what’s makes us all
is found heterozygous, the odds of these are things we can look at now different, it’s the way we’re made up
factor V Leidens having a clotting and make sure that people don’t genetically.
event in their lifetime are much have those clotting events, we can
greater than someone without thin their bloods with fish oils and Wendy: And so this affect how
the mutation. Factor V Leiden other fatty acids. It is important enzymes work and proteins work
is sometimes called activated to be monitored throughout your and various functions work in the
protein C resistance, because lifetime if you have this mutation. body or don’t work?
this mutation leads to protein C These people are at higher risk of
resistance. And when pregnant, developing DVT, especially when on Sterling: Yes.
the uterus is fed with capillaries, hormone therapy or birth control.
so the miscarriage is related to this Wendy: Yes. So when you run your
particular mutation. And you need There is another one, HFE, that one app, Sterlings App, and look at the
to remember that this is a gene is known as the hereditary SNPBits Compendium, which I’m
where you’ll rarely see someone assuming that’s the report.
homozygous, because it is usually hemochromatosis gene. These
not caught before a major clotting people, when dealing with long- Sterling: That’s the book that goes
event first. term elevated ferritin issues, with the report.
have T-cell excitotoxicity and are
Factor V Leiden can be serious more prone to Lyme disease and Wendy: Oh, okay, that’s the book
even when heterozygous. So autoimmune diseases like MS. It is that goes with the report. So
when someone knows that he or best for them to avoid ascorbic acid how can that help someone with
she has FVL, it is best for them and focus on taking C cofactors and supplementation?
to have a physician run their vitamin C foods rather than the out
platelet, C-reactive protein, and of shelf that we know is ascorbic Sterling: Okay. Well, I created this
fibrinogen. It is easily manageable. acid. app for people with chronic health
These people are at high risk of issues. So it doesn’t matter what
developing DVTs, especially when Wendy: Yes. And can you explain they take as far as supplements,
on hormone therapy or birth exactly what you mean by you have that one difficult patient
control. And they need to really homozygous and heterozygous, all the time, and they take one
speak with their practitioner if they just for anyone out there who’s not step forward and two steps back.
And we’ve got this report so Wendy: But you get that consult with me or cannot afford to
practitioners can get to the root complimentary if you run your pay for my apps. I truly believe that
cause and help their patients. And genes through the Sterling’s App? if you are a true healer, you do not
we never ever put in our variant turn anyone away. And I also like,
reports what to take because I Sterling: No. This book was the fecal uBiome testing. Have you
call this, treating the SNP and not extremely—I mean it’s huge. It’s an ever heard of uBiome?
the person. I want practitioners eight by eleven, 350-page book that
to learn this, I do teach this to the took about five years of research Wendy: Oh, yeah.
practitioners. from three different people to put
together in here. And Cynthia Smith Sterling: Yes. They’re great. And I’m
I also get told by some practitioners at Life Zone Wellness had to put it hoping, because everything’s kind
that there are so many SNPs, that it all together and it was pretty pricey of jumbled on there, kind of like
is complicated. Well, I mean, that’s for her to put this book together raw data with 23andME. I’m having,
what makes us all different. Like our and self-publish. in the next year, me and my team,
fingerprints, our DNA is all different. that works on my apps constantly
And should I leave out a SNP that Wendy: How much does that book all year-round, round the clock, that
can be crucial to some of them cost? we can kind of put together an easy
because practitioners want easy, I guide for practitioners.
don’t think that’s right to the person Sterling: I believe it’s $49.95, but
who’s ill, so I’ll never do that. we do give out promo codes and So they don’t have to go into
discounts quite often. And when, people’s uBiomes and just say,
So many factors do come into like I said, somebody does not have “Oh, okay I got to go research this.
play in a person’s gut health. money, we do our best. Now that It’s low, where do I get this? How
Diet, lifestyle, stress, genetics, I’m not in complete ownership with can I replace this microbial in this
and environmental factors this book and she is. She will give person?” And we’re going to try to
are important to look at as a discounts to people who really want make it easier in the near future
whole. So you just can’t look it even at her cost if possible. for people. The gut one, I think, is
at the report, you need to put the most important one, because
everything together. And I do Wendy: Where can you get the healing that is so important for
teach doctors, scientists, and I’ve book? anybody to detox, for anybody
even taught a Nobel laureate how to assimilate their food, and get
nutrigenomics can heal people and Sterling: You can get at my store at nutrition.
get people off of their prescription MTHFRsupport.com.
medications by manipulating their And then one of the most important
DNA with nutritional food and Wendy: And what other tests test is The Great Plains Lab Organic
supplementation. are good to look at regarding Acid Test, because it is most reliable
supplementation? when testing for poor sulfation and
And then, I also, with the help of hyperoxaluria. 90% of chronically
Cynthia Smith, she’s a colleague of Sterling: Well, I believe, the ill people have this issue and I truly
mine, the Lifezonewellness.com. genetic profile like I have at MTHFR believe GMO is one of the reasons
Amazing lady. She helped me get Support, I would also like to tell why 90% of the population who are
this book together, I gave her my people that are wary of doing chronically ill have this issue. And
data and she put in her data as their DNA with 23andME or DNA one of the reason that many cannot
well as Carolyn Ledowsky from Ancestry, use a fake name. I prefer heal is because of poor sulfation
MTHFRsupport.com Australia. And 23andMe over the DNA Ancestry and hyperoxaluria, which must be
we made a 350-page book—it’s because it has much more raw data addressed before you can work on
huge—to show people what we on the back end. We are always methylation.
found to go as a user guide with updating our variant report, which
the variant report. So I helped is stored and secure and does not These tests along with our variant
compile much of the research go out to any third parties. We report can go a long way in
and our SNPBits Compendium for now have an excipient report for someone’s recovery. I absolutely
practitioners to better understand children who have been vaccine cringe when I see practitioners
genetic function, which we sell at damaged. doing the same protocol on
our store at MTHFR Support. everyone, because we must always
Again, like I said, I never turn remember that one man’s food is
anyone away that cannot afford to indeed another man’s poison.
Wendy: Yes, absolutely, absolutely. My name is Wendy Myers. And my
So where can listeners learn more hope is that you and your family
about you? And there’s a podcast experience abundant health, and
also on your website as well, that all begins with taking the right
correct? supplements.

Sterling: Yeah. And we’re also


starting DNAedu.org, kind of
working with Steven Fox. He left
the CDC and has been a big person
trying to get glyphosate out of food.
And people like Stephanie Seneff
from MIT are where we’re going
to shoot off with this DNAedu.
org, where we really want to
teach people, have classes that
practitioners can join, and teach
how toxins are damaging DNA
and what can we do to avoid them
and repair it and fix it. And I think
that’s big.

And then MTHFRsupport.com,


you know of course. I have a lot of
interviews coming up in the very
near future, of course, with this
Washington, D.C. thing I’m headed
out to. And all the interviews and
stuff, I will be putting at MTHFR
Support. And also, I’ll have a section
at DNAedu.org, once I have that site
up and running. But I think that site
is very important that we can start
giving classes two to four times a
month and teaching practitioners,
because this is really difficult to
learn but it is so important.

Wendy: Absolutely. Well, as far as I


know, you guys definitely an earful
today, definitely an education on
your DNA. But thank you so much,
again, for joining the Medicinal
Supplements Summit. And you
can’t get more laser-light focus
in your supplementation regime
than supplementing based on your
genetic.

So, please, take home this life-


changing information home with
you by clicking on the banner
beside or below our talk. And
please share it with your loved
ones.
Express the Power in
Your DNA
Alicia Lynn Diaz, MA, AHP with Charan Surdhar,
BSc, MSc
Click here to watch this interview!
The purpose of this presentation is to convey information.
It is not intended to diagnose, treat, or cure your condition or to be a substitute
for advice from your physician or other healthcare professional.

She’s been featured on The Hidden family, then the thing is, you’re just
Science, TV show, and in the thinking, well, there’s no choice. If
Alicia: Welcome, everyone! Alicia upcoming movie, Punk Science. someone’s got breast cancer in their
Lynn here, from AliciaLynnDiaz. She’s also a book author and she family, and then they’re thinking,
com. And I’m really excited to has a huge passion for creating well, I’ve got no choice, this is the
welcome you to this very special animated videos to explain in a way my life is going to be. Or, if it’s
section of The Soul of Healing simple way, these big concepts diabetes or heart disease, and you
Summit, because today we’re such as epigenetics, which you can can name quite a few conditions.
talking with Charan Surdhar. And find on her YouTube channel. She’s
as you all know, I felt really called also endorsed by the renowned So, the epigenetics aspect is
to put this summit together to help Dr. Bruce Lipton and Dr. Christiane basically taking people out of that
you harness the power of your Northrup. paradigm of, I’m a victim to my
mind and spirit to create radical genes, to a completely empowering
self-healing. And, Charan’s topic So, again, Charan, I’m so honored aspect of being, which is to say
that she’ll be sharing with us today, to have you hear today. Thank you that actually, you are in control of
is, how you can express the power for joining us. how your DNA and your genes are
in your DNA. expressed.
Charan: Thank you, Alicia. It’s such
And Charan Surdhar is a geneticist a pleasure to be here. And the reason, because the word
turned epigeneticist, from her epigenetics, epi means above,
innermost desire to reveal the truth Alicia: Yeah. So, I think a great the genes. Whereas genes is just
about our human potential. She first start would be how would you everything, the genes contribute
has a Bachelor in Science degree define epigenetics? Because, I think to everything. And if you inherit a
in Microbiology, and a Master in this is going to be a new topic for particular gene, then it’s just the
Science degree in Human Genetics. a lot of our viewers and make sure way it is. Epigenetics suggests, and
And she has worked in the field of that we start off all on the same says that epi is above to gene, so
genetics for 13 years, identifying page. everything that is contributing to
genetic mutations for a whole how those genes are expressed, is
host of genetic diseases. And she’s Charan: Yes. So, it would be a great above the genes. So, that’s a really
contributed to scientific papers and one to start off with. So, genetics, very, very important different there.
textbooks. a lot of people are familiar with
genes, DNA, and genetics being And epi itself, when you think
So today, she works specifically the study of genes, and how the about it, above the genes, then
with genetic diseases, assisting to genes function and all that. But the question is, well, what is it that
release the energy in the forms of the genetics aspect of things has contributes to the genes then, if it’s
emotions, beliefs, and perception shifted to the epigenetics. And let not the DNA? If you think about it,
that ends up getting in the way me explain how and why. if you’re having a building built, and
of the natural flow of the body. you know you have the architect
And this brings about positive So, genetics is more about if you draw out a blueprint, that blueprint
gene expression. Charan truly is have something going on in your is not going to build the house. It’s
leading edge in this paradigm shift family, if there’s any diseases or going to be the people that come
in the revolutionary new field of conditions passed down in your in and decide where those bricks
epigenetics.
are going to be laid, how they’re hear in that, if you’ve got conditions, that vision, that vision is that light,
going to be laid, how they’re going you’ve got situations going on. that beauty that exists within all of
to decorate, and that whole aspect. us. And really it’s just about being
So, using that analogy, this is how And I get that. But, the important able to get to that, and express it.
epigenetics becomes a new way of thing here to realize is that there is
being. And that it takes us out of this inner perfection already there. Alicia: Wow! That’s such a beautiful
that place of being a victim to our It’s like that diamond that already imagery. I just want to invite you
biology, into being empowered in exists within us. And this light all to take that, what Charan just
our life. switch for the Christmas lights, as said, really just take that into your
soon as we embody into this body, mind for a moment and really feel
Alicia: Wow! Charan, this is a where we’re in, we have that power what she just said. It sounds like
really powerful topic. So, what within us. you’re suggesting that the architect,
you’re suggesting is that our genes who created the DNA, has been
oftentimes, for all of you that are And, I always say to my clients and something that has been passed
listening, we hear, we see our family say to people, the DNA is listening down.
history, and then there’s a tendency to everything you’re saying,
to think like, we essentially give everything you’re being. And not But the person who wrote up
ourselves a life sentence to this just you, but all that energy that we those architectural designs, it can
gene expression. have inherited from our parents, be implemented in different ways,
that point of conception which and that person who created it,
But, what you’re suggesting is that comes from our ancestors, it’s had a vision to create it. So, you’re
the genes themselves, the blueprint there. It’s there and it’s around this actually suggesting that we can
that you’re handed down from diamond. And it’s affecting how the have that vision for our health, and
your lineage, from your family, is light shines from the diamond. But our DNA responds in such a way
just that. It’s just the blueprint. And it doesn’t mean that the diamond’s that it’s actually creating a new way
so, we actually through our diet, not there. of being.
lifestyle, maybe there are some
things that you’re going to share And so, the work that I do is really Charan: Absolutely. I’ve never
with us, but there’s a way to express to allow for that diamond to just really expressed it in that way, it
the genes that is really reclaiming be able to shine. And it’s to those came through. So, it’s perfect for
our power in the process. layers that are there, to just begin whichever way it comes through.
to allow for the client, I don’t do And that’s absolutely it.
Charan: Yes, absolutely. And, while anything, it’s to allow people to
I was saying all that, what came into actually begin to release that, in Because consciousness is that, the
my head was another analogy, and order to then be able to be who architect, the person that had that
this is going to how we can express we’re here to be. creative inspiration, not a person,
the power in our DNA. Maybe I’m but had that perfection. It’s that
jumping the gun here, but it’s just And that is what then the DNA perfection that exists within us. It’s
come to me. So, if you have some can listen to and express. Because that creative force that’s within us.
Christmas lights, so if you imagine every gene can be expressed 30,000 And when we can touch that, and
the analogy of Christmas lights. different ways, 30,000 different be that, that’s when our DNA begins
And, Christmas lights are just the ways! And when we have this stuff to express itself in a way that’s just
way they are. But it needs that around the DNA, it’s what the DNA magnificent.
switch to allow for those lights to is listening to, it’s shifting. It’s a
come on. blueprint. If you have an architect And I know that the way I say it, it
come in, and the builders come in, sounds like it’s really easy, but then
DNA is very similar. And we’re and then they say, “Well, I want it when you’re going through things
talking about the power behind, this way.” And then one of them in your life, it’s difficult. And I totally
the essence of how we can express goes, “I want it this way,” and so on get that.
our DNA. Each one of us has that and so forth.
internal power, that soul power, And, I can say that it’s not
which is within us, from spirit, from And you have all that kind of something that happens, it can
consciousness, that is within us. coming in. But the original person have moments where you express
We are perfection already. There is who made the blueprint, who had that, when you have moments of
nothing to change, nothing to shift, the creative inspiration to do that, being creative yourself, moments
and that maybe hard for people to it’s all a vision. And when you have of joy, moments of gratitude, all of
that, it comes through you in those science because I heard you also that can then shift the way that the
moments. But, a lot of my clients say a few things like, every gene can DNA’s expressed.
have things like, say for instance, be expressed 30,000 different ways,
I get clients with lots of issues, and all these different switches that So this is where that, every gene
whether it’s genetic, or whether it’s allows a DNA gene to be expressed can be expressed 30,000 different
emotional issues, or other things or to maybe remain dormant. And ways, if we’re not in tune with that,
like that. so, I’m curious how you’ve seen in or if we don’t allow ourselves to
the lab, so to speak, these things tune into those sensations without
And if it’s an issue where self- show up that you’re speaking of. judgement, we continue to allow
confidence or self-love, and for the body to manifest or express
they’ll push through life, and Charan: I’m glad you asked that the genes in a way that it has
keep pushing, and pushing, and question, because yes, it’s very been doing, or continues to do,
pushing, and think, well, I just can’t important. Just to backtrack, when I and that can be a continuation of
seem to get to that self-love. I just said about joy and gratitude, those inflammation, all that.
can’t seem to have that. As I keep two things, whether it’s compassion,
pushing, and I keep trying, and I joy, love, I felt this was important But when we do that, it can allow
just can’t get it. And then when I to mention before answering your for the DNA to be expressed in a
work with them, we uncover the question, that we are always taught way that decreases inflammation.
layers that are over that diamond, that you’ve got to stay in joy, you’ve So, these sensations, like I said
and you see that, and each person’s got to be that way. before, it’s very important to also
different, so this is just one specific say that they may not just be from
example, but you have that energy But, I want to clarify that it’s very you, it’s a collective. It could be a
that’s been passed on. important to recognize, to be collective, it could be ancestral. Is it
present to exactly what you’re okay if I mention a study?
Say there was an emotion that’s feeling because when we’re present
been passed on, of self-abuse. to that, when we’re present to Alicia: Please. Great.
Self-abuse meaning mentally what we’re feeling, and we go into
abusing yourself constantly, from the body because we have the Charan: There was a study done in
generations back. And it could be tendency to leave the body at that Northern Europe, where they have
11, 20 generations. And this person time because it’s just too much, records of many generations ago,
is feeling this and is trying to move to feel into the sensations, this is of all the people that lived, what
through it, thinking it’s all their fault, where the science meets the spirit they went through, and everything
they’re trying to move through it, or the soul. And that is, that those that they experienced in their lives.
but it’s actually this inherited energy sensations that we can feel in our And what they wanted to do was,
that’s there, that once shifted, body, is exactly what the DNA is to look at what they’d experienced
allows for that diamond to show up. listening to. and what impact it had on their
grandchildren, who are alive now.
And it’s moments, just going back So, when we can tune into those
to what I was saying, we have these sensations, we then move into a And what they found was that,
moments where we can shine. And place of bringing that awareness or I always get goosebumps when
then we have moments where we consciousness to it, the switch to I talk about this one, they said
recognize that I’m not feeling that the Christmas lights, and it allows what they found was, they had the
great right now. But, it’s in those that to shift, in the way that the individuals that were living then, the
moments also that we’re being DNA is expressed. So, if we run grandparents of these individuals
shown that there’s another aspect away from our sensations, the body now, when they went through
to us that we can then just tune into will continue to hold on to that. It’s draught, or famine, at particular
and allow for that to shift. Yeah, I a gift. times in their life, for males it was
could go on and on. more, if they were impacted, if they
And it will begin to manifest as pain, were going through that at puberty.
Alicia: Yeah, this is great. And it’s or you’ll have other things show up And for females, it was when they
a very empowering position. And in your life. It’s a message from our were in the womb, because that’s
I’m curious where the intersection body, without judgement, to go in when the eggs form, and that’s
point is with this sort of creative and be present to those sensations when the sperm form for the men.
consciousness, spiritual things that allow us to then tune into what And, what they found was that the
that you’re expressing right now, the DNA is listening to, allow us grandchildren of those individuals
and where that intersects with the to bring consciousness to it. And had diabetes. So, that’s one study.
There’s a very popular study that’s and collective and all that, that can kind of energetic field of, above
been going on around social media, influence us. Just to illustrate how the DNA, that kind of somewhat
as well, which is to do with mice we can collectively feel things, The controls the gene expression. So, I
and the cherry blossom. What they HeartMath Institute has been doing would just love for you to talk a little
found was that initially they did the some really amazing research. bit about that, how our viewers can
experiment where they shocked harness that power themselves.
these mice every time they smelled And they have these instruments
the cherry blossom. And, Alicia, around the planet where they Charan: Yes. You said it beautifully.
we always think things like panic measure, I’m not pretty sure how A lot of people say, “Well, I can’t
attacks and people think that, oh they measure, what they do, but feel the sensations.” And that’s
that’s got to be something I’ve done, they measure the energy understandable because we’re so
or it’s something I need to deal with. of the collective. And what they did geared up to be receptive to the
was, they had these instruments in outside, that there’s so much going
Something must have happened place before 9/11, for the purpose on, on the outside with the internet,
and it’s there. And, I’ve done a of what I’m trying to say here, and and social media and everything in
lot of techniques and things, and they were measuring what the our lives, the whole thing. So, we
what works really is the fact that, energy was like. And what they saw rarely get time to just tune in.
to go back to that analogy of those was that before 9/11 happened,
Christmas lights with a switch, if there was a peak in the chart. And And this is really where science
we can get back to that, it allows it was significant to suggest that meets spirit because they really
for that DNA to shift in a way that everyone felt something before it weren’t ever, ever separate. And,
allows you to move in a way that happened. So, my point here is that, one of the things when I was
it allows you to express the DNA we as the collective pick up more working in the laboratory many
to not have those reactions again. than we even know. years ago was, it was always the
And I’ll explain that with the cherry debate of, is it nurture or nature.
blossom experiment. Alicia: Wow! So, what do you And in my mind, there was always
attribute this energetic to, if it’s this thing about I can never see how
So, these mice were having the beyond the DNA, if it’s beyond that could be different. And I just
smell of this cherry blossom. And even the physical kind of genetic knew it. I just knew in my head that
every time they did that, they would expression? Is there a way that our there was no versus in that. It was
shock them. I don’t always agree viewers can learn how to harness actually together.
with these experiments with mice, some of this power?
but then, there we go. So, every And so this is where it really does
time they were shocked, obviously I think, to clarify my question, you come together in that when we
they, it was that Pavlov’s response were sharing about this idea that can feel those sensations. So, like I
kind of thing, where they just didn’t it’s a misconception to think, well, said, many people find it difficult to
want to smell it. we always just have to feel good, tune into those sensations, and if
that we should always be enjoying you say to people, to the audience,
Now, what they did was, then the gratitude, and compassion. And if you’re sitting on a chair, can you
children of those mice, and the then there ends up being a feeling feel yourself on that chair. They’ll
next generation, and then the next of, well, when I’m feeling bad, that say, “Yeah. Well, yes I can.” Okay, so,
generation, what they found was means I’m doing something wrong. if you eat something, can you feel
that those generations were not So, I have to just get back to feeling that sensation in your mouth?
actually shocked or they’d never good, which can really create like a Yes. If you touch your forehead, you
smelled cherry blossom, but when bypass situation. could feel that.
they were introduced to the smell
of cherry blossom, they did not So, I really loved what you shared, So, it’s about beginning to train
want to smell it. It was just an and I’m really glad that you ourselves again, to begin to feel
instant reaction that they just didn’t clarified that. So, what you’re these sensations. And it’s really
want to. actually suggesting is that all of critical, it’s really truly, I can’t begin
human emotion actually creates to even say how critical and so
So, this is really important because, sensation in the physical body. And magnificently beautiful it is, that
this goes to show that, we think something around this sensation when we can begin to touch that
that a lot of everything we feel and and being just honest and truthful space, how it begins to impact how
be, is us, but there’s frequencies about where you are in any given our genes are expressed.
behind that, frequencies, ancestral moment, is how you access this
So, with regards to harnessing it, the opportunity to just simply be there is a lot that’s happened. And
it is in every moment being aware with that and feel that, without just in our own history, that we’re
of what sensations you’re feeling. needing to make that mean aware of, we know that World War
And at times, it can be so intense anything or change it, you’re just II and the gassings and all this stuff,
that we don’t want to. If you’re allowing yourself to come into the there’s so much. And it does affect,
going through some trauma, or here and now, with what’s present like the study I mentioned.
something going on in our lives, it’s for you, and what you’re feeling in
difficult, because the mind goes off any given moment. Another study that they did with
on its own tangent. But if we can 9/11 survivors, was with pregnant
really go inside and say, well, if I And then that is actually, it sounds women. And what they found was
had mentioned 9/11, I was doing a so simple, but from a scientific that these women that were in their
Facebook live post the other day, standpoint, from an epigeneticist third trimester, during 9/11, gave
and I was just saying, okay, feel it. standpoint, this is the space birth to children whose cortisol
Everyone was saying, well, yeah, that creates radical shifts, that levels were much higher.
I feel it, 9/11. I can feel that. And creates the retraining of the gene So, that means that basically
where do you feel it? expression so that you’re not they have more susceptibility to
sentenced to what your ancestors, heart disease and other chronic
Someone would say, I felt it in my what your previous generations conditions as a result of that. And
chest. I was there, and this and that. have experienced in their health. this is just because the mother was
Okay, well, let’s feel that. And, as we exposed to that in her environment.
were feeling it, everyone was tuning I think it really brings up, Charan, So, there is a lot more to that.
into these sensations. I was getting this idea of the environment as
them to give a rating from zero to well, for gene expression. And And when you were saying all that,
10 on it, where they were at. And when we think of our parents, what came to me to say, and add
the numbers shifted dramatically our grandparents, our great- to this, is that, yes, that’s all doom
because we were just tuning into grandparents, and knowing that and gloom, and yes, it all happened.
that sensation. And of course they had certain maybe disease But the other empowering thing
there’s other ways that I work with processes that they dealt with, to know here, is that when you
people, but this is a critical, very, there was also an environment that tune into yourself and begin to,
very empowering way that people contributed to that disease process. moment to moment recognize
can begin to shift their biology. the sensations and allow that
For example, the environment consciousness, the awareness
Alicia: This is a really great of stress, environments that are that’s within you…Because when
takeaway practice for all of you creating stress on the body and you’re in that moment, that’s what
listening, what Charan is sharing. creating that shutdown-ness, or the you’re doing, you’re allowing that
Even just where you are right now, environmental aspects of toxins awareness to come through and
you can tune into the physical that they were exposed to. Or the shine its light inside. And then
sensation of the chair that you’re way that they had to eat, based on the DNA then responds to that.
sitting in. You can tune into the the current knowledge that they But when you’re doing that for
physical sensation of you putting had about diet and nutrition at that yourself, what happens is that you
your hands on different areas of time. Or, based on their financial shift things not only for yourself,
your body, saying that, “Okay, I feel status of what they could afford to but you’re shifting things for the
that.” eat, or not to eat. whole planet. And why? And how?
So, the environment that you’re Because, it happens. I’ve seen that.
And then, what she’s suggesting in right now, is there anything
is, when you tune into different that you want to speak to from an I have permission to share this
life events for yourself, for society, environmental influence? from a client whose daughter has
and just feel the, more subtle, it’s cystic fibrosis or had. She’s got the
a more subtle sensation, but allow Charan: Yes. There is so much. genes for it. And cystic fibrosis is a
yourself to just intuitively go to, When I’m working with clients and condition where children don’t live
well, what area of your body do we release the energy that’s from very long. And they continuously
you feel that subtle sensation. And past generations, it’s incredible get a lot of mucous production in
that’s an emotional sensation. what things that have happened their lungs. It’s a genetic disorder.
in our past: hangings, guillotines. And they have a very short life. And
And so, what I’m hearing is that, I don’t go into all those specifics the prognosis is not good.
moment to moment, giving yourself with clients but the thing is that
When their daughter was diagnosed and doing some work with wave Alicia: This is mind blowing. And I’m
with that, mom and dad decided genetics. I went to a conference so grateful to you and your work.
that they were not going to go into where he was presenting 2 years It’s making me increasingly curious
that belief system of believing that ago. And, he was presenting where about your story, which I was going
she was going to die. And they did there was a child who was brought to ask you in the beginning and
not talk about cystic fibrosis in the to him, who had a genetic disorder. then we just went on this whole
house. They treated her normally. And her prognosis as well wasn’t beautiful conversation and went
And she was well. But there came very good. And she was only given a deeper.
a point where she began to cough little while to live.
and having some regular infections. But, like you have such a passion
This is fascinating. This is truly, for this, and such a gift for this. And
And so, they got in touch with me. truly fascinating. This is where I’m just curious what really got you
And we did some work. And there we’re moving in powerful ways of from being a geneticist, to pursuing
was a lot of inherited energy that being. And we know that this is why epigenetics with the passion that
needed to be released, from many, epigenetics works, this is where you have. Was there something in
many generations back. And, that we can be empowered with all this your personal life or something that
was released and she is normal. information. He has a machine that you saw in your work that propelled
She’s going to school. She’s gone he reads energy off people. this desire?
past the age that they said that she
would. And she’s doing well. So, what he did was, he had this Charan: When I was a child, when I
machine. He got the girl’s cousin, was about 11, I think it was around
But the other thing that happened who was normal. And he recorded then that AIDS actually came
in the family, was that not only did this energy frequency of her cousin. about on the planet. And when I
she benefit, but her sister who had And he put it into an mp3 file. And heard that on the news, there was
eczema, that eczema disappeared he played this to her. Well, he got something that just got ignited in
because when we released it from the parents to do it. And she then me. I was listening to news and
her, these energies which were in manifested in physical symptoms everything. People were saying,
her sister, as well, and obviously that were normal. So, she “We’ve got to find a cure for this.
from one of the parents, and the absolutely began to manifest like a We’ve got to find this. We’ve got to
ancestors, it releases all of it. It’s normal child. So that was powerful. do this.”
like a domino effect. And, if you
imagine that, if that energy went And another study that he had And there was something that just
back 20 generations, there’s many done—and I can never remember ignited in me and said, there’s got
individuals that live now that are which way around it was—but he to be another way. And, I wrote
ancestors of that one individual. And had frog eggs and salamander eggs. down a list. And one of the things
they possibly have inherited it too. And I can’t remember which way on the list was to cure AIDS. I’m not
around he did it. But he took the doing that, and nor do I actually
So, when you’re doing this work for frequency of, let’s say it was the frog claim to cure anything.
yourself, you’re not just releasing it eggs. And we’ll have to check it out. But, as a child, there was a passion
for yourself, but you’re releasing it But let’s say for example, he took that came through there that I
for the whole, like I said. And when the frequency of frog eggs. And he wanted to be able to do this. And I
I do this work and test it, it is being played it to the salamander eggs. saw myself in a laboratory, working
released from the whole of those And when the salamander eggs and doing that. So, that’s how I
individuals. And the intention is hatched, they were frogs. Isn’t that ended up in the laboratory. And
there for it to be released from the just amazing? that passion stayed with me.
planet. So, this work, it’s powerful.
It’s totally powerful. There’s another Alicia: What?! That’s incredible! And, as I was working in the
study, can I just mention that? laboratory with DNA, with the
Charan: It’s incredible! And so, different genetic disorders, there
Alicia: Please. I was going to ask this is why, your question with was still something in there that
you, please share more studies, regards to the environment, this is wasn’t complete. It just wasn’t
stories. These are so captivating epigenetics, this is the energy above complete. And, when I heard about
and so powerful. the genes. We can influence that by epigenetics, and the impact that
tuning into our sensations. This is the thoughts, and beliefs, and
Charan: Peter Gariaev, who is a the impact that you can have. everything else that we’ve talked
Russian scientist, living in Russia, about today, that can impact our
biology, it was like I had just come of science and spirit, in a really, it is that frequency. It is that,
full circle. From that little girl to truly empowering way for others, being in that space of awareness,
now, just that was it. I just knew. and your work is powerful, and consciousness, that itself does the
I just knew that this is it. And, so fascinating. work.
that’s where that passion comes
from. And I’ve seen it in my clients. And I’m curious, so, is there Alicia: Yes. And that’s really tying
anything like, I hear you referring back to, my last question was going
And just another example, again I to some of these clients that you’re to be do you have any additional
have permission to share this, there working with. What does the words of encouragement or
was a girl that I worked on just a process look like, of actually finding “advice” to our listeners on how
couple of days ago, an 11 year old those inherited emotions within they can apply all the beautiful
with anemia. someone, these energies, and like things you just shared, into their
what you just said, finding some of own life. And I think you just started
And she had all the tests done, these even physiological markers speaking to that. But, I give you the
they couldn’t find anything. And we of cortisol or things like that? And floor, if there is anything else you
worked on her. And I was on Skype. then, what does the process of want to share with us.
And I could see, her face was pale, clearing that look like when you’re
lips blue. And we found inherited working with someone? Or is that Charan: Well, I’ll go back to what
emotions in her, going back many too much? we started off with, which is really
generations, that were influencing to trust and know that you have
her in such a way to, initially it was Charan: Well, no. I use muscle this perfection already within you,
actually creating an energetically testing in order to be able to tune speaking to the audience. That that
broken heart. into my client, and also obviously is already there. That diamond,
as more and more I’ve been doing you’re there. It’s there.
Another thing that one of the that, it’s the intuition. But a lot
emotions was contributing to was of my work is intention. And it’s And how do we access it? We allow
actually an excess of cortisol in holding the intention of seeing and ourselves, this is very important,
the body. So, really, at point of knowing that that diamond exists in we allow ourselves to feel every
conception, she had inherited this everyone. sensation in our body. Allow
from one of her parents, and it was ourselves to be with ourselves.
contributing to her having an excess There’s the quantum physics aspect And, as we do that, it allows for that
of cortisol. And it was contributing of it. When I first started this work, consciousness to encompass us in
to the anemia. And then also the I’ve grown in this work myself. And such a beautiful way that it begins
broken heart. it was that there’s layers and layers to clear things in our life, our body,
and layers and layers. And let’s clear allows the DNA expression to move
So, by clearing that, Alicia, right them, there must be another layer into the alignment that it’s meant
after the session on Skype, her face here. There’s something wrong. to be.
is pink, her lips are pink, and she’s Let’s keep going. No, I don’t do that
smiling. And the mom’s looking at anymore, because that’s what we And, it allows everyone on the
her, I’ve never seen her glowing will keep seeing. And this is why I planet to shift, as with the examples
like this. It’s things like that just started the call off in that way, that we’ve already shared. We’re all
warm my heart. And it’s that what there is that perfection, and this powerful. We’re so powerful,
continues to feed my passion, to be is why we can express the power beyond belief. We need to
able to let people know that, like in our DNA. Because that already recognize that now.
you said, we’re not sentenced to the exists within.
way that things are showing up for Alicia: Yes, it’s time.
us. And things can shift. And, when I tune into clients, that’s
what I see. And it’s just holding that Charan: Yeah.
Alicia: Wow! What a perfect space for them that then allows for
illustration, what you just shared. things to bubble up. And it’s not Alicia: Thank you. Such an honor
And it’s so beautiful that your me. It’s not me, Alicia. And it never to have you, Charan. Gosh! I really
passion was born from such a has been, never will be. And it’s just encourage every single one of you
young age. I can really relate to being present to that awareness to visit Charan’s website, www.
that. And so, your path has been within myself that allows the client CharanSurdhar.com. And you’ll see
so beautiful. And the merging to be in that energy to allow them her name’s spelling on the main
of this, really like intersection to then recognize that because page.
So, Charan, thank you. Thank you,
thank you, thank you. This was
profound wisdom that you shared.
Thank you for all of the studies and
case studies you shared as well. I
really, truly value your contribution
today.

Charan: Thank you, Alicia. Thank


you. It’s just a pleasure to be able to
share my passion.

Alicia: Yes. Many blessings to all


of you. And go ahead and visit
Charan’s website, CharanSurdhar.
com, to learn more about how she
can support you throughout this
healing journey, and creating radical
self-healing. So, lots of love. Again,
this has been Charan Surdhar and
Alicia Lynn Diaz with the Soul of
Healing Summit. Take care.
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